Nrf2
Nrf2 is a transcription factor that regulates the expression of antioxidant proteins and detoxification enzymes, playing a pivotal role in cellular defense against oxidative stress and inflammation. Activation of Nrf2 signaling provides protection against various diseases, including cancer, neurodegeneration, and cardiovascular disorders. Nrf2 modulators are being explored for their potential therapeutic applications in reducing oxidative damage and inflammation. At CymitQuimica, we provide a range of high-quality Nrf2 pathway modulators to support your research in oxidative stress, inflammation, and disease prevention.
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AEM1
CAS:1030123-90-0
AEM1 is an inhibitor of deregulated NRF2 transcriptional activity in cancer.
Formula:
C20H14FN3O2S
Purity:
97.87%
Color and Shape:
Solid
Molecular weight:
379.41
Ref: TM-T8979
| 5mg | 51.00 € | ||
| 10mg | 90.00 € | ||
| 25mg | 171.00 € | ||
| 50mg | 291.00 € | ||
| 100mg | 499.00 € | ||
| 1mL*10mM (DMSO) | 89.00 € |
Estimated delivery in United States, on Friday 21 Feb 2025
4-Octyl itaconate
CAS:3133-16-2
4-Octyl Itaconate is a cell-permeable derivative of Itaconate, an anti-inflammatory metabolite.
Formula:
C13H22O4
Purity:
99.3% - 99.87%
Color and Shape:
Solid
Molecular weight:
242.31
Ref: TM-T4580
| 25mg | 36.00 € | ||
| 50mg | 48.00 € | ||
| 100mg | 64.00 € | ||
| 1mL*10mM (DMSO) | 52.00 € |
Estimated delivery in United States, on Friday 21 Feb 2025
Trilobatin
CAS:4192-90-9
Trilobatin (P-Phlorizin) has anti-oxidant effect, can increase superoxide dismutase (SOD) activity.Trilobatin has anti-inflammatory effect, it …
Formula:
C21H24O10
Purity:
97.16%
Color and Shape:
Solid
Molecular weight:
436.41
Ref: TM-T2S0731
| 1mg | 63.00 € | ||
| 5mg | 122.00 € | ||
| 10mg | 162.00 € | ||
| 25mg | 316.00 € | ||
| 50mg | 477.00 € | ||
| 100mg | 694.00 € | ||
| 1mL*10mM (DMSO) | 136.00 € |
Estimated delivery in United States, on Friday 21 Feb 2025
Brusatol
CAS:14907-98-3
Brusatol (NSC-172924) is a natural product isolated from the Brucea javanica plant. It inhibits Nrf2.
Formula:
C26H32O11
Purity:
99.35% - 99.82%
Color and Shape:
Solid
Molecular weight:
520.53
Ref: TM-TQ0211
| 1mg | 41.00 € | ||
| 5mg | 97.00 € | ||
| 10mg | 166.00 € | ||
| 25mg | 323.00 € | ||
| 50mg | 521.00 € | ||
| 100mg | 741.00 € | ||
| 200mg | 971.00 € | ||
| 1mL*10mM (DMSO) | 111.00 € |
Estimated delivery in United States, on Friday 21 Feb 2025
K67
CAS:2046250-48-8
K67 competitively inhibits the interaction between Nrf2-ETGE and Keap1 and can be used to study …
Formula:
C29H30N2O7S2
Purity:
98.43%
Color and Shape:
Solid
Molecular weight:
582.69
Ref: TM-T27709
| 2mg | 133.00 € |
Estimated delivery in United States, on Friday 4 Apr 2025
![(E)-[6]-Dehydroparadol](https://static.cymitquimica.com/products/TM/thumb/T13436.jpg)
(E)-[6]-Dehydroparadol
CAS:878006-06-5
(E)-[6]-Dehydroparadol ((6)-Dehydroparadol), an oxidative metabolite of [6]-Shogaol, is a potent Nrf2 activator.
Formula:
C17H24O3
Purity:
99.87%
Color and Shape:
Solid
Molecular weight:
276.37
Ref: TM-T13436
| 1mg | 43.00 € | ||
| 5mg | 91.00 € | ||
| 10mg | 114.00 € | ||
| 25mg | 203.00 € | ||
| 50mg | 276.00 € | ||
| 100mg | 397.00 € | ||
| 500mg | 898.00 € | ||
| 1mL*10mM (DMSO) | 92.00 € |
Estimated delivery in United States, on Friday 4 Apr 2025
DDO-7263
CAS:2254004-96-9
DDO-7263, a 1,2,4-Oxadiazole, boosts Nrf2 by binding Rpn6, blocking 26S proteasome assembly, and has anti-inflammatory …
Formula:
C14H9F2N3O
Purity:
99.75%
Color and Shape:
Liquid
Molecular weight:
273.24
Ref: TM-T60487
| 1mg | 60.00 € | ||
| 5mg | 131.00 € | ||
| 10mg | 209.00 € | ||
| 25mg | 347.00 € | ||
| 50mg | 460.00 € | ||
| 100mg | 602.00 € | ||
| 1mL*10mM (DMSO) | 96.00 € |
Estimated delivery in United States, on Friday 4 Apr 2025
CDDO-EA
CAS:932730-51-3
CDDO-EA (CDDO ethyl amide) is an activator of the Nrf2/antioxidant response element.
Formula:
C33H46N2O3
Purity:
98.54%
Color and Shape:
Solid
Molecular weight:
518.73
Ref: TM-T10733
| 1mg | 88.00 € | ||
| 5mg | 169.00 € | ||
| 10mg | 307.00 € | ||
| 25mg | 528.00 € | ||
| 50mg | 756.00 € | ||
| 100mg | 974.00 € | ||
| 200mg | 1,305.00 € | ||
| 1mL*10mM (DMSO) | 194.00 € |
Estimated delivery in United States, on Friday 4 Apr 2025
Dihydrolipoic acid
CAS:462-20-4
Dihydrolipoic acid (USAF XR-12), a dithiol carboxylic acid, is a potent antioxidant active against various …
Formula:
C8H16O2S2
Purity:
≥98%
Color and Shape:
Yellow To Orange Liquid
Molecular weight:
208.34
Ref: TM-T21233
| 25mg | 137.00 € | ||
| 50mg | 211.00 € |
Estimated delivery in United States, on Friday 4 Apr 2025
Nrf2-IN-1
CAS:1610022-76-8
Nrf2-IN-1 is an nuclear factor-erythroid 2-related factor 2 (Nrf2) inhibitor. Nrf2-IN-1 is developed for the …
Formula:
C21H22ClN3O2
Purity:
95.00% - 99.68%
Color and Shape:
Solid
Molecular weight:
383.87
Ref: TM-T12253
| 1mg | 113.00 € | ||
| 5mg | 271.00 € | ||
| 10mg | 372.00 € | ||
| 25mg | 616.00 € | ||
| 50mg | 857.00 € | ||
| 100mg | 1,173.00 € | ||
| 500mg | 2,301.00 € | ||
| 1mL*10mM (DMSO) | 298.00 € |
Estimated delivery in United States, on Monday 21 Apr 2025
Nrf2-IN-3
CAS:6325-13-9
Nrf2-IN-3 is an NRF2 inhibitor that selectively sensitizes xenografts of mouse mKEAP1 cancer cells to …
Formula:
C22H26N4O4S
Color and Shape:
Liquid
Molecular weight:
442.53
Ref: TM-T78841
| 1mg | 94.00 € | ||
| 5mg | 197.00 € | ||
| 10mg | 321.00 € | ||
| 25mg | 637.00 € | ||
| 50mg | 1,007.00 € | ||
| 100mg | 1,644.00 € |
Estimated delivery in United States, on Monday 21 Apr 2025
VVD-130037
CAS:3034880-93-5
VVD-130037 is a KEAP1 activator with potential antitumor activity.VVD-130037 inhibits tumor growth in advanced solid …
Formula:
C17H17ClN4O2
Color and Shape:
Liquid
Molecular weight:
344.8
Ref: TM-T88838
| 1mg | 164.00 € | ||
| 5mg | 388.00 € | ||
| 10mg | 564.00 € | ||
| 25mg | 910.00 € | ||
| 50mg | 1,238.00 € |
Estimated delivery in United States, on Friday 16 May 2025
KI696
CAS:1799974-70-1
KI696 is a high-affinity probe that potently inhibits the interaction of Keap1 and NRF2.
Formula:
C28H30N4O6S
Purity:
98.42%
Color and Shape:
Solid
Molecular weight:
550.63
Ref: TM-T11758L
| 1mg | 143.00 € | ||
| 5mg | 343.00 € | ||
| 10mg | 547.00 € | ||
| 25mg | 1,003.00 € | ||
| 50mg | 1,374.00 € | ||
| 100mg | 1,828.00 € | ||
| 1mL*10mM (DMSO) | 446.00 € |
Estimated delivery in United States, on Friday 16 May 2025
