CXCR
CXCRs are a subset of GPCRs that bind to chemokines, small signaling proteins that guide the movement of immune cells towards sites of inflammation, infection, or injury. CXCRs play crucial roles in immune responses, cancer metastasis, and inflammatory diseases. Modulators of CXCRs are being investigated for their potential in treating autoimmune diseases, cancer, and chronic inflammatory conditions. At CymitQuimica, we offer a range of high-quality CXCR modulators to support your research in immunology, oncology, and inflammation.
Found 154 products of "CXCR"
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ITIC
CAS:"ITIC, a non-fullerene acceptor with high Tg of 180°C, shows excellent thermal stability and a low glass-crystal transition, plus unique crystallization."Formula:C94H82N4O2S4Purity:98%Color and Shape:SolidMolecular weight:1427.96CXCR7 modulator 1
CAS:CXCR7 modulator 1 is an effective and orally bioavailable peptoid hybrid CXCR7 modulator with Ki of 9 nM.Formula:C48H57F2N7O7SPurity:98%Color and Shape:SolidMolecular weight:914.07CTCE-9908
CAS:CXCR4 blocker; triggers cell division failure in ovarian cancer, boosts taxol and docetaxel treatment effects, proven in mice.Formula:C86H147N27O23Purity:98%Color and Shape:SolidMolecular weight:1927.27RCP168
RCP168 is a highly selective and potent CXCR4 receptor antagonist with an IC50 of 5 nM. It exhibits superior capacity to inhibit HIV-1 (Human Immunodeficiency Virus type 1) from entering host cells via the CXCR4 receptor compared to natural chemokines. RCP168 suppresses HIV-1 infection by blocking viral binding sites or inducing receptor internalization. It can be utilized in research to study interactions between the CXCR4 receptor and other chemokine receptors.Formula:C365H585N105O95S5Molecular weight:8119.27766PS372424 hydrochloride
CAS:PS372424 hydrochloride,CXCR3 agonist. Anti-inflammatory. Inhibits T-cell migration.Formula:C33H45ClN6O4Purity:95.03%Color and Shape:SolidMolecular weight:625.2ATI-2341
CAS:ATI-2341, pepducin targeting the CXCR4, is an allosteric agonist activating the Gi to promote inhibition of cAMP production and induce calcium mobilization.Formula:C104H178N26O25S2Color and Shape:SolidMolecular weight:2256.82ACT-1004-1239
CAS:ACT-1004-1239 is a CXCR7 antagonist with immunomodulatory and myelination-promoting effects, used for research on inflammatory demyelinating diseases.
Formula:C27H28F2N6O3Purity:98.31%Color and Shape:SolidMolecular weight:522.55CXCR2 antagonist 8
CAS:CXCR2 antagonist 8 is a selective CXCR2 antagonist, which can be used for the treatment and prevention of insulin resistance.Formula:C14H13N3O5Color and Shape:SolidMolecular weight:303.27LY2510924
CAS:LY2510924 is an effective and selective CXCR4 antagonist. It blocks SDF-1 binding to CXCR4 (IC50: 0.079 nM).Formula:C62H88N14O10Color and Shape:SolidMolecular weight:1189.45Peptide R TFA
Peptide R (TFA) is a synthetic and specific CXCR4 antagonist. It demonstrates excellent tumor stroma remodeling capabilities and is applicable in research on solid tumors, such as glioblastoma.Formula:C39H57N13O8S2·xC2HF3O2Color and Shape:SolidMolecular weight:900.08 (free base)Motixafortide
CAS:Motixafortide (BKT140 4-fluorobenzoyl) is an antagonist of CXCR4 (IC50: 1 nM).Formula:C97H144FN33O19S2Purity:98%Color and Shape:SolidMolecular weight:2159.52Navarixin
CAS:Navarixin (MK-7123)(SCH527123) is a novel, selective CXC chemokine receptor 2(CXCR2) antagonist that inhibits neutrophil activation and modulates neutrophilFormula:C21H23N3O5Purity:98% - 99.51%Color and Shape:SolidMolecular weight:397.42Ref: TM-T7130
1mg38.00€5mg80.00€10mg114.00€25mg200.00€50mg299.00€100mg442.00€500mg973.00€1mL*10mM (DMSO)88.00€ML339
CAS:ML339 a selective inhibitor of CXCR6(IC50 = 140 nM) with no response when screened against CXCR5 and CXCR4.
Formula:C26H32ClN3O5Purity:99.9%Color and Shape:SolidMolecular weight:502WZ811
CAS:WZ811 is a novel and effective small molecular CXCR4 antagonist (EC50: 0.3 nM).Formula:C18H18N4Purity:99.42% - ≥95%Color and Shape:SolidMolecular weight:290.36AMD-070 hydrochloride
CAS:AMD-070 hydrochloride is a CXCR4 antagonist, is useful for Anti HIV.Formula:C21H28ClN5Purity:98.38% - 98.57%Color and Shape:SolidMolecular weight:385.93JMS-17-2 hydrochloride
CAS:JMS-17-2 hydrochloride: potent CX3CR1 blocker, IC50 of 0.32 nM, hinders breast cancer metastasis.Formula:C25H27Cl2N3OColor and Shape:SolidMolecular weight:456.41USL311
CAS:USL311 blocks CXCR4/SDF-1 interaction, inhibits tumor cell growth and migration.Formula:C24H34N6OPurity:98.46% - 99.56%Color and Shape:SolidMolecular weight:422.57Ref: TM-T17208
1mg42.00€5mg88.00€10mg127.00€25mg250.00€50mg393.00€100mg628.00€500mg1,304.00€1mL*10mM (DMSO)87.00€UNBS5162
CAS:UNBS5162 (UNBS-5162) is a novel naphthalimide that decreases CXCL chemokine expression in experimental prostate cancers.Formula:C17H18N4O3Purity:98.37% - 99.97%Color and Shape:SolidMolecular weight:326.35Ref: TM-T2477
1mg39.00€5mg81.00€10mg116.00€25mg215.00€50mg340.00€100mg540.00€200mg787.00€1mL*10mM (DMSO)89.00€SB225002
CAS:SB225002 is a potent and selective CXCR2 antagonist inhibiting interleukin IL-8 binding to CXCR2.Formula:C13H10BrN3O4Purity:98.16% - 99.85%Color and Shape:SolidMolecular weight:352.14Ref: TM-T1955
5mg48.00€10mg63.00€25mg120.00€50mg213.00€100mg383.00€200mg585.00€500mg888.00€1mL*10mM (DMSO)50.00€MSX-122
CAS:MSX-122 is a novel small molecule and partial CXCR4 antagonist, with potent inhibition of CXCR4/CXCL12 actions(IC50 = 10 nM).Formula:C16H16N6Purity:98.31% - 98.94%Color and Shape:SolidMolecular weight:292.34
