CXCR
CXCRs are a subset of GPCRs that bind to chemokines, small signaling proteins that guide the movement of immune cells towards sites of inflammation, infection, or injury. CXCRs play crucial roles in immune responses, cancer metastasis, and inflammatory diseases. Modulators of CXCRs are being investigated for their potential in treating autoimmune diseases, cancer, and chronic inflammatory conditions. At CymitQuimica, we offer a range of high-quality CXCR modulators to support your research in immunology, oncology, and inflammation.
Found 154 products of "CXCR"
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MSX-130
CAS:MSX-130 is CXCR4 Antagonist.Formula:C36H26N4Purity:99.19%Color and Shape:SolidMolecular weight:514.62JMS-17-2
CAS:JMS-17-2 is a potent and selective antagonist of CX3CR1( IC50 : 0.32 nM).Formula:C25H26ClN3OPurity:98.7% - 99.44%Color and Shape:SolidMolecular weight:419.95Ref: TM-T5849
1mg35.00€5mg78.00€10mg117.00€25mg198.00€50mg310.00€100mg460.00€200mg665.00€1mL*10mM (DMSO)87.00€SB-265610
CAS:SB-265610 (GSK-CXCR2) is a nonpeptide and allosteric CXCR2 antagonist.Formula:C14H9BrN6OPurity:99.5%Color and Shape:SolidMolecular weight:357.16Ref: TM-T16850
1mg52.00€5mg113.00€10mg177.00€25mg356.00€50mg530.00€100mg758.00€500mg1,558.00€1mL*10mM (DMSO)124.00€Danirixin
CAS:Danirixin (GSK1325756) is a potent antagonist of CXCR2 that inhibits IL-8 binding to CXCR2 (IC50: 12.5 nM).Formula:C19H21ClFN3O4SPurity:99.78% - >99.99%Color and Shape:SolidMolecular weight:441.9Ref: TM-T5193
1mg58.00€5mg105.00€10mg170.00€25mg318.00€50mg505.00€100mg713.00€200mg982.00€1mL*10mM (DMSO)102.00€Nicotinamide N-oxide
CAS:Nicotinamide N-oxide, a metabolite of nicotinamide and precursor to NAD+, is reduced by liver enzyme xanthine oxidase.Formula:C6H6N2O2Purity:99.66% - 99.9%Color and Shape:SolidMolecular weight:138.12WZ811
CAS:WZ811 is a novel and effective small molecular CXCR4 antagonist (EC50: 0.3 nM).Formula:C18H18N4Purity:99.42% - ≥95%Color and Shape:SolidMolecular weight:290.36SX-682
CAS:SX-682 is an orally available allosteric inhibitor of CXCR1 and CXCR2.Cost-effective and quality-assured.Formula:C19H14BF4N3O4SPurity:98.19% - 99.61%Color and Shape:SolidMolecular weight:467.2SRT3109
CAS:SRT3109 is a CXCR2 ligand used in the treatment of chemokine mediated diseases and conditions.Formula:C18H23F2N5O4S2Purity:99.65% - 99.92%Color and Shape:SolidMolecular weight:475.53Elubrixin HCl
CAS:Elubrixin is a interleukin 8 inhibitor and CXCR2 selective antagonist.Formula:C17H18Cl3FN4O4SColor and Shape:SolidMolecular weight:499.77Baohuoside I
CAS:Baohuoside I (Icariside-II) is a component of Epimedium koreanum, exhibits anti-inflammatory activity and anti-osteoporosis activities.Formula:C27H30O10Purity:97.64% - 98.14%Color and Shape:SolidMolecular weight:514.52Ref: TM-T3396
2mg43.00€5mg63.00€10mg92.00€25mg170.00€50mg268.00€100mg447.00€200mg623.00€1mL*10mM (DMSO)123.00€Mavorixafor trihydrochloride
CAS:Mavorixafor trihydrochloride blocks CXCR4 (IC50: 13 nM) and suppresses T-tropic HIV-1 replication (IC50: 1-9 nM). It's orally active.Formula:C21H30Cl3N5Purity:98.00%Color and Shape:SolidMolecular weight:458.86Plerixafor octahydrochloride
CAS:Plerixafor octahydrochloride mobilizes HSCs by blocking SDF-1alpha/CXCR4 interaction, facilitating their release into circulation.Formula:C28H62Cl8N8Purity:98.01% - 99.79%Color and Shape:SolidMolecular weight:794.46SB225002
CAS:SB225002 is a potent and selective CXCR2 antagonist inhibiting interleukin IL-8 binding to CXCR2.Formula:C13H10BrN3O4Purity:98.16% - 99.85%Color and Shape:SolidMolecular weight:352.14Ref: TM-T1955
5mg48.00€10mg63.00€25mg120.00€50mg213.00€100mg383.00€200mg585.00€500mg888.00€1mL*10mM (DMSO)50.00€USL311
CAS:USL311 blocks CXCR4/SDF-1 interaction, inhibits tumor cell growth and migration.Formula:C24H34N6OPurity:98.46% - 99.56%Color and Shape:SolidMolecular weight:422.57Ref: TM-T17208
1mg42.00€5mg88.00€10mg127.00€25mg250.00€50mg393.00€100mg628.00€500mg1,304.00€1mL*10mM (DMSO)87.00€UNBS5162
CAS:UNBS5162 (UNBS-5162) is a novel naphthalimide that decreases CXCL chemokine expression in experimental prostate cancers.Formula:C17H18N4O3Purity:98.37% - 99.97%Color and Shape:SolidMolecular weight:326.35Ref: TM-T2477
1mg39.00€5mg81.00€10mg116.00€25mg215.00€50mg340.00€100mg540.00€200mg787.00€1mL*10mM (DMSO)89.00€JMS-17-2 hydrochloride
CAS:JMS-17-2 hydrochloride: potent CX3CR1 blocker, IC50 of 0.32 nM, hinders breast cancer metastasis.Formula:C25H27Cl2N3OColor and Shape:SolidMolecular weight:456.41MSX-122
CAS:MSX-122 is a novel small molecule and partial CXCR4 antagonist, with potent inhibition of CXCR4/CXCL12 actions(IC50 = 10 nM).Formula:C16H16N6Purity:98.31% - 98.94%Color and Shape:SolidMolecular weight:292.34AZD-5069
CAS:AZD-5069 is an chemokine receptor 2 antagonist (CXCR2; IC50 = 0.79 nM).Formula:C18H22F2N4O5S2Purity:98.38% - 98.63%Color and Shape:SolidMolecular weight:476.52Ref: TM-T7681
1mg34.00€2mg47.00€5mg66.00€10mg98.00€25mg190.00€50mg295.00€100mg447.00€200mg623.00€1mL*10mM (DMSO)73.00€Reparixin
CAS:Reparixin inhibits CXCR1 (IC50=1 nM) strongly, CXCR2 weakly (IC50=100 nM), and it's a CXCL8 receptor blocker.Formula:C14H21NO3SPurity:98% - 99.89%Color and Shape:SolidMolecular weight:283.39Ref: TM-T4163
5mg48.00€10mg62.00€25mg120.00€50mg187.00€100mg301.00€200mg449.00€1mL*10mM (DMSO)111.00€TAK-779
CAS:TAK-779 (Takeda 779) is an antagonist of chemokine receptor 5 (CCR5), CCR2b, and CXC chemokine receptor 3 (CXCR3).Formula:C33H39ClN2O2Purity:99.21%Color and Shape:SolidMolecular weight:531.13
