CXCR
CXCRs are a subset of GPCRs that bind to chemokines, small signaling proteins that guide the movement of immune cells towards sites of inflammation, infection, or injury. CXCRs play crucial roles in immune responses, cancer metastasis, and inflammatory diseases. Modulators of CXCRs are being investigated for their potential in treating autoimmune diseases, cancer, and chronic inflammatory conditions. At CymitQuimica, we offer a range of high-quality CXCR modulators to support your research in immunology, oncology, and inflammation.
Found 158 products of "CXCR"
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SX-682
CAS:SX-682 is an orally available allosteric inhibitor of CXCR1 and CXCR2.Cost-effective and quality-assured.Formula:C19H14BF4N3O4SPurity:98.19% - 99.61%Color and Shape:SolidMolecular weight:467.2SRT3109
CAS:SRT3109 is a CXCR2 ligand used in the treatment of chemokine mediated diseases and conditions.Formula:C18H23F2N5O4S2Purity:99.65% - 99.92%Color and Shape:SolidMolecular weight:475.53Baohuoside I
CAS:Baohuoside I (Icariside-II) is a component of Epimedium koreanum, exhibits anti-inflammatory activity and anti-osteoporosis activities.Formula:C27H30O10Purity:97.64% - 98.14%Color and Shape:SolidMolecular weight:514.52Ref: TM-T3396
2mg43.00€5mg63.00€10mg92.00€25mg170.00€50mg268.00€100mg447.00€200mg623.00€1mL*10mM (DMSO)123.00€Reparixin
CAS:Reparixin inhibits CXCR1 (IC50=1 nM) strongly, CXCR2 weakly (IC50=100 nM), and it's a CXCL8 receptor blocker.Formula:C14H21NO3SPurity:98% - 99.89%Color and Shape:SolidMolecular weight:283.39Ref: TM-T4163
5mg48.00€10mg62.00€25mg120.00€50mg187.00€100mg301.00€200mg449.00€1mL*10mM (DMSO)111.00€TAK-779
CAS:TAK-779 (Takeda 779) is an antagonist of chemokine receptor 5 (CCR5), CCR2b, and CXC chemokine receptor 3 (CXCR3).Formula:C33H39ClN2O2Purity:99.21%Color and Shape:SolidMolecular weight:531.13MSX-130
CAS:MSX-130 is CXCR4 Antagonist.Formula:C36H26N4Purity:99.19%Color and Shape:SolidMolecular weight:514.62ML 145
CAS:ML 145 is a selective antagonist of GPR35/CXCR8 (IC50/EC50 of 20.1 nM)Formula:C24H22N2O5S2Purity:97.74%Color and Shape:SolidMolecular weight:482.57Ref: TM-T12074
1mg52.00€5mg100.00€10mg149.00€25mg250.00€50mg408.00€100mg572.00€1mL*10mM (DMSO)109.00€rac-NBI-74330
CAS:rac-NBI-74330 is an effective and selective CXCR3 antagonist.Formula:C32H27F4N5O3Purity:99.6%Color and Shape:SolidMolecular weight:605.58CXCR4 modulator-2
CAS:CXCR4 modulator-2 (Z7R) has high potency (IC50: 1.25 nM), stable in mouse serum (t1/2=77.1 min), and anti-inflammatory in mice.Formula:C21H32N8O2Color and Shape:SolidMolecular weight:428.53SRT3190
CAS:SRT3190 is an antagonist of CXCR2.Formula:C18H23F2N5O4S2Purity:98%Color and Shape:SolidMolecular weight:475.53AMG 487 (S-enantiomer)
CAS:AMG 487 S-enantiomer is the S enantiomer of AMG 487. AMG 487 is an CXCR3 antagonist.Formula:C32H28F3N5O4Purity:98%Color and Shape:SolidMolecular weight:603.59ICT5040
CAS:ICT5040 is a CXCR4 antagonist.Formula:C10H8F3N3OSColor and Shape:SolidMolecular weight:275.25VUF10132
CAS:VUF10132 is a full inverse CXCR3 N3.35A agonist.Formula:C19H13BrCl4N2O2Purity:98%Color and Shape:SolidMolecular weight:523.03CXCR4 antagonist 9
CAS:CXCR4 antagonist 9, with IC50s of 15 nM & 1.3 nM against CXCR4 & Ca²⁺ rise by CXCL12 respectively.Formula:C21H27FN6Color and Shape:SolidMolecular weight:382.48SB-332235
CAS:SB-332235 is an effective specific CXCR2 antagonist. And it is effectively inhibited CS-induced neutrophilia in a dose-dependent manner.Formula:C13H10Cl3N3O4SColor and Shape:SolidMolecular weight:410.66VUF5834
CAS:VUF5834 is a full inverse agonist of CXCR3 N3.35A.Formula:C31H41N5O2Purity:98%Color and Shape:SolidMolecular weight:515.69IT1t
CAS:IT1t inhibits CXCL12/CXCR4 interaction with an IC50 of 2.1 nM. is a potent CXCR4 antagonist.Formula:C21H34N4S2Purity:98%Color and Shape:SolidMolecular weight:406.65CXCR3 Antagonist 6c
CAS:CXCR3 antagonist 6c blocks CXCR3 and inhibits Ca2+ movement and T-cell migration (IC50: 0.06 µM & 100 nM) with selectivity over 14 other GPCRs.Formula:C30H32Cl3N5O3Color and Shape:SolidMolecular weight:616.97CXCR4 antagonist 5
CAS:CXCR4 antagonist with IC50 of 8.8 nM, inhibits CXCL12-induced calcium increase and chemotaxis, with good safety and minimal CYP, hERG impact.Formula:C21H30N6Color and Shape:SolidMolecular weight:366.5ACT-660602
CAS:ACT-660602: Oral CXCR3 blocker, T-cell migration inhibitor, effective in acute lung injury models, potential for autoimmune research. IC50: 204 nM.Formula:C20H20F6N8OSColor and Shape:SolidMolecular weight:534.48
