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CXCR

CXCR

CXCRs are a subset of GPCRs that bind to chemokines, small signaling proteins that guide the movement of immune cells towards sites of inflammation, infection, or injury. CXCRs play crucial roles in immune responses, cancer metastasis, and inflammatory diseases. Modulators of CXCRs are being investigated for their potential in treating autoimmune diseases, cancer, and chronic inflammatory conditions. At CymitQuimica, we offer a range of high-quality CXCR modulators to support your research in immunology, oncology, and inflammation.

Found 147 products of "CXCR"

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  • ML 145
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    ML 145

    CAS:
    <p>ML 145 is a selective antagonist of GPR35/CXCR8 (IC50/EC50 of 20.1 nM)</p>
    Formula:C24H22N2O5S2
    Purity:97.74%
    Color and Shape:Solid
    Molecular weight:482.57

    Ref: TM-T12074

  • HF51116
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    HF51116

    CAS:
    <p>HF51116 blocks XCR4, hinders SDF-1α cell effects &amp; HIV-1; potential for HIV, stem cells, cancer spread.</p>
    Formula:C29H46N8O
    Color and Shape:Solid
    Molecular weight:522.73

    Ref: TM-T63661

  • CXCR3 Antagonist 6c
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    CXCR3 Antagonist 6c

    CAS:
    <p>CXCR3 antagonist 6c blocks CXCR3 and inhibits Ca2+ movement and T-cell migration (IC50: 0.06 µM &amp; 100 nM) with selectivity over 14 other GPCRs.</p>
    Formula:C30H32Cl3N5O3
    Color and Shape:Solid
    Molecular weight:616.97

    Ref: TM-T36982

  • CXCR4 antagonist 9
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    CXCR4 antagonist 9

    CAS:
    <p>CXCR4 antagonist 9, with IC50s of 15 nM &amp; 1.3 nM against CXCR4 &amp; Ca²⁺ rise by CXCL12 respectively.</p>
    Formula:C21H27FN6
    Color and Shape:Solid
    Molecular weight:382.48

    Ref: TM-T61650

  • VUF10132
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    VUF10132

    CAS:
    <p>VUF10132 is a full inverse CXCR3 N3.35A agonist.</p>
    Formula:C19H13BrCl4N2O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:523.03

    Ref: TM-T24949

  • AMG 487 (S-enantiomer)
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    AMG 487 (S-enantiomer)

    CAS:
    <p>AMG 487 S-enantiomer is the S enantiomer of AMG 487. AMG 487 is an CXCR3 antagonist.</p>
    Formula:C32H28F3N5O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:603.59

    Ref: TM-T10297

  • HF50731
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    HF50731

    CAS:
    <p>HF50731 is a CXCR4 antagonist with high binding affinity (IC50: 19.8 nM) and inhibits calcium mobilization, cell migration, and HIV-1 (IC50: 1.5 nM).</p>
    Formula:C26H46N4
    Color and Shape:Solid
    Molecular weight:414.67

    Ref: TM-T62140

  • SRT3190
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    SRT3190

    CAS:
    <p>SRT3190 is an antagonist of CXCR2.</p>
    Formula:C18H23F2N5O4S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:475.53

    Ref: TM-T16933

  • CXCR4 modulator-2
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    CXCR4 modulator-2

    CAS:
    <p>CXCR4 modulator-2 (Z7R) has high potency (IC50: 1.25 nM), stable in mouse serum (t1/2=77.1 min), and anti-inflammatory in mice.</p>
    Formula:C21H32N8O2
    Color and Shape:Solid
    Molecular weight:428.53

    Ref: TM-T62352

  • ICT5040
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    ICT5040

    CAS:
    <p>ICT5040 is a CXCR4 antagonist.</p>
    Formula:C10H8F3N3OS
    Color and Shape:Solid
    Molecular weight:275.25

    Ref: TM-T25523

  • SB-332235
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    SB-332235

    CAS:
    <p>SB-332235 is an effective specific CXCR2 antagonist. And it is effectively inhibited CS-induced neutrophilia in a dose-dependent manner.</p>
    Formula:C13H10Cl3N3O4S
    Color and Shape:Solid
    Molecular weight:410.66

    Ref: TM-T34544

  • VUF11211
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    VUF11211

    CAS:
    <p>VUF11211 is an effective antagonist of CXCR3 that acts by extending from the minor pocket into the major pocket of the transmembrane domains.</p>
    Formula:C26H35Cl2N5O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:504.49

    Ref: TM-T23656

  • TN-14003
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    TN-14003

    CAS:
    <p>TN-14003 is a synthetic antagonist 14-mer peptide inhibiting metastasis in an animal model.</p>
    Formula:C90H141N33O18S2
    Color and Shape:Solid
    Molecular weight:2037.42

    Ref: TM-T69347

  • CXCR4 antagonist 8
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    CXCR4 antagonist 8

    CAS:
    <p>CXCR4 antagonist 8 (Compound 3) blocks CXCR4, IC50 of 57 nM; stops CXCL12-induced Ca2+ increase, IC50 of 0.24 nM; hinders cell migration.</p>
    Formula:C21H26N6
    Color and Shape:Solid
    Molecular weight:362.47

    Ref: TM-T61363

  • CXCR4 antagonist 5
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    CXCR4 antagonist 5

    CAS:
    <p>CXCR4 antagonist with IC50 of 8.8 nM, inhibits CXCL12-induced calcium increase and chemotaxis, with good safety and minimal CYP, hERG impact.</p>
    Formula:C21H30N6
    Color and Shape:Solid
    Molecular weight:366.5

    Ref: TM-T61419

  • SX-517
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    SX-517

    CAS:
    <p>SX-517 is a non-competitive dual antagonist of CXCR1/2, demonstrating anti-inflammatory effects, inhibits CXCL-1-induced Ca²⁺ flux.</p>
    Formula:C19H16BFN2O3S
    Color and Shape:Solid
    Molecular weight:382.22

    Ref: TM-T28893

  • KRH-1636
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    KRH-1636

    CAS:
    <p>KRH-1636: potent, selective CXCR4 antagonist; orally active; inhibits X4 HIV-1 by blocking viral entry and membrane fusion.</p>
    Formula:C32H37N7O2
    Color and Shape:Solid
    Molecular weight:551.68

    Ref: TM-T69081

  • IT1t
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    IT1t

    CAS:
    <p>IT1t inhibits CXCL12/CXCR4 interaction with an IC50 of 2.1 nM. is a potent CXCR4 antagonist.</p>
    Formula:C21H34N4S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:406.65

    Ref: TM-T11693

  • Burixafor hydrobromide
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    Burixafor hydrobromide

    CAS:
    <p>Burixafor hydrobromide is an oral CXCR4 blocker with anti-angiogenic properties, potentially treating choroid neovascularization.</p>
    Formula:C27H52BrN8O3P
    Purity:98%
    Color and Shape:Solid
    Molecular weight:647.644

    Ref: TM-T10635

  • VUF5834
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    VUF5834

    CAS:
    <p>VUF5834 is a full inverse agonist of CXCR3 N3.35A.</p>
    Formula:C31H41N5O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:515.69

    Ref: TM-T29147