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CXCR

CXCR

CXCRs are a subset of GPCRs that bind to chemokines, small signaling proteins that guide the movement of immune cells towards sites of inflammation, infection, or injury. CXCRs play crucial roles in immune responses, cancer metastasis, and inflammatory diseases. Modulators of CXCRs are being investigated for their potential in treating autoimmune diseases, cancer, and chronic inflammatory conditions. At CymitQuimica, we offer a range of high-quality CXCR modulators to support your research in immunology, oncology, and inflammation.

Found 147 products of "CXCR"

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  • rac-NBI-74330
    Targetmol
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    rac-NBI-74330

    CAS:
    <p>rac-NBI-74330 is an effective and selective CXCR3 antagonist.</p>
    Formula:C32H27F4N5O3
    Purity:99.6%
    Color and Shape:Solid
    Molecular weight:605.58

    Ref: TM-T26035

  • PS372424
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    PS372424

    CAS:
    <p>PS372424 is a specific agonist of human CXCR3, with anti-inflammatory activity.</p>
    Formula:C33H44N6O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:588.74

    Ref: TM-T12567

  • AZ10397767
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    AZ10397767

    CAS:
    <p>AZ10397767: Potent CXCR2 blocker (IC50=1nM); lowers neutrophil infiltration in tumors in vitro/in vivo.</p>
    Formula:C15H14ClFN4O2S2
    Color and Shape:Solid
    Molecular weight:400.88

    Ref: TM-T26699

  • AMD 3465
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    AMD 3465

    CAS:
    <p>AMD 3465 (GENZ-644494) blocks CXCR4, hinders X4 HIV replication (IC50: 1-10 nM), ineffective against R5 viruses, IC50: 0.75 nM (12G5 mAb), 18 nM (CXCL12AF647).</p>
    Formula:C24H38N6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:410.60

    Ref: TM-T14208

  • SCH 546738
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    SCH 546738

    CAS:
    <p>SCH 546738 is an orally available, selective and potent CXCR3 antagonist that attenuates the development of autoimmune diseases and delays graft rejection.</p>
    Formula:C23H31Cl2N7O
    Purity:98.67%
    Color and Shape:Solid
    Molecular weight:492.45

    Ref: TM-T16863

  • GPR35 agonist 1
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    GPR35 agonist 1

    CAS:
    <p>GPR35 agonist 1 is a highly effective and specific GPR35/CXCR8 agonist (EC50: 5.8 nM).</p>
    Formula:C10H4BrN5O5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:354.07

    Ref: TM-T11455

  • FC131
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    FC131

    CAS:
    <p>CXCR4 antagonist</p>
    Formula:C36H47N11O6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:729.83

    Ref: TM-T22777

  • SB02024
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    SB02024

    CAS:
    <p>SB02024 inhibits VPS34, boosts cGAS-STING, hinders autophagy, and shrinks breast cancer xenografts; enhances Sunitinib/Erlotinib efficacy.</p>
    Formula:C16H22F3N3O2
    Color and Shape:Solid
    Molecular weight:345.36

    Ref: TM-T69888

  • ACT-660602
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    ACT-660602

    CAS:
    <p>ACT-660602: Oral CXCR3 blocker, T-cell migration inhibitor, effective in acute lung injury models, potential for autoimmune research. IC50: 204 nM.</p>
    Formula:C20H20F6N8OS
    Color and Shape:Solid
    Molecular weight:534.48

    Ref: TM-T63761

  • IT1t dihydrochloride
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    IT1t dihydrochloride

    CAS:
    <p>IT1t dihydrochloride inhibits CXCL12/CXCR4 interaction with IC50 of 2.1 nM. IT1t dihydrochloride is an antagonist of CXCR4.</p>
    Formula:C21H36Cl2N4S2
    Purity:99.91%
    Color and Shape:Solid
    Molecular weight:479.57

    Ref: TM-T11693L

  • Mavorixafor
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    Mavorixafor

    CAS:
    <p>Mavorixafor (AMD-070) is an effective and selective antagonist of CXCR4, with an IC50 value of 13 nM against CXCR4 125I-SDF binding.</p>
    Formula:C21H27N5
    Purity:98.56%
    Color and Shape:Solid
    Molecular weight:349.47

    Ref: TM-TQ0174

  • NUCC-390
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    NUCC-390

    CAS:
    <p>NUCC-390, a novel small-molecule CXCR4 receptor agonist, selectively induces CXCR4 receptor internalization while acting antagonistically to AMD3100.</p>
    Formula:C23H33N5O
    Purity:97.08%
    Color and Shape:Solid
    Molecular weight:395.54

    Ref: TM-T12269

  • AZD8797
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    AZD8797

    CAS:
    <p>AZD8797 (KAND567) is a CX3CR1 antagonist with potential protective effects against neuronal damage and prevents nociceptive hypersensitivity in rats.</p>
    Formula:C19H25N5OS2
    Purity:98.73% - 99.68%
    Color and Shape:Solid
    Molecular weight:403.56

    Ref: TM-T14384

  • Elubrixin
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    Elubrixin

    CAS:
    <p>Elubrixin (SB-656933) inhibits neutrophil CD11b upregulation (IC50 of 260.7 nM) and shape change (IC50 of 310.5 nM).</p>
    Formula:C17H17Cl2FN4O4S
    Purity:98.65% - 99.78%
    Color and Shape:Solid
    Molecular weight:463.31

    Ref: TM-T11179

  • AZD8309
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    AZD8309

    CAS:
    <p>AZD8309 is an oral CXCR2 antagonist, curbing neutrophil movement, lowering MPO in lungs/pancreas, and trypsin/elastase activity.</p>
    Formula:C15H14F2N4O2S2
    Purity:98.35% - 99.67%
    Color and Shape:Solid
    Molecular weight:384.42

    Ref: TM-T25131

  • TIQ-15
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    TIQ-15

    CAS:
    <p>TIQ-15 is an effective and selective CXCR4 antagonist. It has good drug-like properties.</p>
    Formula:C23H32N4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:364.53

    Ref: TM-T24886

  • CXCR4 antagonist 6
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    CXCR4 antagonist 6

    CAS:
    <p>CXCR4 antagonist 6 blocks CXCR4 (IC50: 79 nM), hinders calcium flux (IC50: 0.25 nM), reduces cell migration, and is effective in cancer metastasis mice.</p>
    Formula:C21H30N6
    Color and Shape:Solid
    Molecular weight:366.5

    Ref: TM-T61420

  • Ladarixin Sodium
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    Ladarixin Sodium

    CAS:
    <p>Ladarixin Sodium, an Chemokine CXCR antagonist, is used potentially for the treatment of type I diabetes.</p>
    Formula:C11H12F3NNaO6S2
    Color and Shape:Solid
    Molecular weight:398.32

    Ref: TM-T27791

  • (±)-AMG 487
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    (±)-AMG 487

    <p>AMG 487 is an effective and selective antagonist of chemokine receptor 3.</p>
    Formula:C32H28F3N5O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:603.59

    Ref: TM-T22477

  • Pentixafor
    Targetmol
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    Pentixafor

    CAS:
    <p>Pentixafor is a peptide that selectively targets the CXCR4 receptor and can be labeled with Gallium-68 (68Ga) for visualization using positron emission</p>
    Formula:C60H80N14O14
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1221.36

    Ref: TM-T79070