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CXCR

CXCR

CXCRs are a subset of GPCRs that bind to chemokines, small signaling proteins that guide the movement of immune cells towards sites of inflammation, infection, or injury. CXCRs play crucial roles in immune responses, cancer metastasis, and inflammatory diseases. Modulators of CXCRs are being investigated for their potential in treating autoimmune diseases, cancer, and chronic inflammatory conditions. At CymitQuimica, we offer a range of high-quality CXCR modulators to support your research in immunology, oncology, and inflammation.

Found 147 products of "CXCR"

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  • SCH 563705
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    SCH 563705

    CAS:
    <p>SCH 563705 is a CXCR2 and CXCR1 antagonist used in the study of acute respiratory syndrome, chronic obstructive pulmonary disease, and inflammation.</p>
    Formula:C23H27N3O5
    Purity:98.03%
    Color and Shape:Solid
    Molecular weight:425.48

    Ref: TM-T16864

  • SLW131
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    SLW131

    CAS:
    <p>SLW131 (Compound 10) is a CCR7 antagonist with strong affinity, showing a Ki of 9.85 nM. It inhibits CCL19-induced Go protein activation with an IC50 of 29.4 μM and β-arrestin2 recruitment with an IC50 of 6.0 μM. SLW131 also suppresses CCL19-induced morphological changes in primary BMDC cells and CCR7-mediated migration of mouse CD4+ T cells.</p>
    Formula:C21H27N5O5S
    Color and Shape:Solid
    Molecular weight:461.535

    Ref: TM-T205065

  • CCX662
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    CCX662

    CAS:
    <p>CCX662 is a CXCR7 antagonist. It inhibits the binding of 125I-CXCL12 to CXCR7 with an IC50 of 9 nM. This compound is suitable for use in cancer research.</p>
    Formula:C28H37N5O4S
    Color and Shape:Solid
    Molecular weight:539.69

    Ref: TM-T201863

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    CXCR2 antagonist 7

    <p>CXCR2 antagonist 7 is a powerful blocker with IC50s: 0.044 μM for binding, 0.66 μM for calcium mobilization.</p>
    Formula:C14H14F2N6OS
    Color and Shape:Solid
    Molecular weight:352.36

    Ref: TM-T61236

  • ACT-672125
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    ACT-672125

    CAS:
    <p>ACT-672125: Potent CXCR3 blocker, may treat autoimmunity, safe with dose-dependent efficacy in lung inflammation.</p>
    Formula:C25H25F3N10O2S
    Color and Shape:Solid
    Molecular weight:586.59

    Ref: TM-T70616

  • VUF11207 trifluoroacetate salt
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    VUF11207 trifluoroacetate salt

    CAS:
    <p>VUF11207 trifluoroacetate salt is a useful organic compound for research related to life sciences. The catalog number is T66657 and the CAS number is 1378524-41-4.</p>
    Formula:C29H36F4N2O6
    Color and Shape:Solid
    Molecular weight:584.609

    Ref: TM-T66657

    ne
    Discontinued
    Discontinued product
  • CXCR4-IN-1
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    CXCR4-IN-1

    CAS:
    <p>CXCR4-IN-1 (Example C5), with an IC50 of 20 nM, is a potent inhibitor of CXCR4, applicable for the research of various conditions such as cancer, HIV, diabetic</p>
    Formula:C23H32N6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:392.54

    Ref: TM-T79059

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    Discontinued product