CXCR
CXCRs are a subset of GPCRs that bind to chemokines, small signaling proteins that guide the movement of immune cells towards sites of inflammation, infection, or injury. CXCRs play crucial roles in immune responses, cancer metastasis, and inflammatory diseases. Modulators of CXCRs are being investigated for their potential in treating autoimmune diseases, cancer, and chronic inflammatory conditions. At CymitQuimica, we offer a range of high-quality CXCR modulators to support your research in immunology, oncology, and inflammation.
Found 147 products of "CXCR"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Navarixin
CAS:<p>Navarixin (MK-7123)(SCH527123) is a novel, selective CXC chemokine receptor 2(CXCR2) antagonist that inhibits neutrophil activation and modulates neutrophil</p>Formula:C21H23N3O5Purity:98% - 99.51%Color and Shape:SolidMolecular weight:397.42MSX-127
CAS:<p>MSX-127 elicites positive response in peptide CXCR4.</p>Formula:C16H24N2O4Purity:98.43%Color and Shape:SolidMolecular weight:308.37MSX-130
CAS:<p>MSX-130 is CXCR4 Antagonist.</p>Formula:C36H26N4Purity:99.19%Color and Shape:SolidMolecular weight:514.62JMS-17-2 hydrochloride
CAS:<p>JMS-17-2 hydrochloride: potent CX3CR1 blocker, IC50 of 0.32 nM, hinders breast cancer metastasis.</p>Formula:C25H27Cl2N3OColor and Shape:SolidMolecular weight:456.41CTCE 9908 acetate
<p>CTCE 9908 acetate is an antagonist of CXCR4 and inhibits migration in CXCR4-expressing ovarian cancer cells.</p>Formula:C88H151N27O25Purity:98.47%Color and Shape:SolidMolecular weight:1987.31ATI-2341 acetate(1337878-62-2 free base)
<p>ATI-2341 acetate is an effective allosteric agonist of CXCR4, it activates Gα1 instead of Gα13.</p>Formula:C106H182N26O27S2Purity:97.14%Color and Shape:SolidMolecular weight:2316.87Elubrixin HCl
CAS:<p>Elubrixin is a interleukin 8 inhibitor and CXCR2 selective antagonist.</p>Formula:C17H18Cl3FN4O4SColor and Shape:SolidMolecular weight:499.77NUCC-390 dihydrochloride
CAS:<p>NUCC-390, a selective CXCR4 agonist, promotes nerve repair by inducing CXCR4 internalization, opposite to AMD3100.</p>Formula:C23H35Cl2N5OColor and Shape:SolidMolecular weight:468.46Decursin
CAS:<p>Decursin: potential antiepileptic, hepatoprotective, anti-cancer, anti-amnesic; affects NOX activation, PKCα/MAPK/NF-κB pathways, AChE.</p>Formula:C19H20O5Purity:97.22% - 99.84%Color and Shape:SolidMolecular weight:328.36FC131 TFA (606968-52-9 free base)
CAS:<p>FC131 TFA (606968-52-9 free base) (FC131 TFA) is an antagonist of CXCR4 that inhibits the binding of [125I] -sdf-1 to CXCR4(IC50 : 4.5 nM ), and has anti-hiv</p>Formula:C38H48F3N11O8Purity:99.39% - 99.67%Color and Shape:SolidMolecular weight:843.85AZD-5069
CAS:<p>AZD-5069 is an chemokine receptor 2 antagonist (CXCR2; IC50 = 0.79 nM).</p>Formula:C18H22F2N4O5S2Purity:98.38% - 98.63%Color and Shape:SolidMolecular weight:476.52ML339
CAS:<p>ML339 a selective inhibitor of CXCR6(IC50 = 140 nM) with no response when screened against CXCR5 and CXCR4.</p>Formula:C26H32ClN3O5Purity:99.9%Color and Shape:SolidMolecular weight:502AMD 3465 hexahydrobromide
CAS:<p>AMD 3465 hexahydrobromide (GENZ-644494 (hexahydrobromide)) is a CXCR4 receptor antagonist with potential anticancer and anti-HIV activity.</p>Formula:C24H44Br6N6Purity:99.39%Color and Shape:SolidMolecular weight:896.07SB-265610
CAS:<p>SB-265610 (GSK-CXCR2) is a nonpeptide and allosteric CXCR2 antagonist.</p>Formula:C14H9BrN6OPurity:99.5%Color and Shape:SolidMolecular weight:357.16Danirixin
CAS:<p>Danirixin (GSK1325756) is a potent antagonist of CXCR2 that inhibits IL-8 binding to CXCR2 (IC50: 12.5 nM).</p>Formula:C19H21ClFN3O4SPurity:99.78% - >99.99%Color and Shape:SolidMolecular weight:441.9SX-682
CAS:<p>SX-682 is an orally available allosteric inhibitor of CXCR1 and CXCR2.Cost-effective and quality-assured.</p>Formula:C19H14BF4N3O4SPurity:98.19% - 99.57%Color and Shape:SolidMolecular weight:467.2Nicotinamide N-oxide
CAS:<p>Nicotinamide N-oxide, a metabolite of nicotinamide and precursor to NAD+, is reduced by liver enzyme xanthine oxidase.</p>Formula:C6H6N2O2Purity:99.66% - 99.9%Color and Shape:SolidMolecular weight:138.12Plerixafor octahydrochloride
CAS:<p>Plerixafor octahydrochloride mobilizes HSCs by blocking SDF-1alpha/CXCR4 interaction, facilitating their release into circulation.</p>Formula:C28H62Cl8N8Purity:98.01% - 99.79%Color and Shape:SolidMolecular weight:794.46TAK-779
CAS:<p>TAK-779 (Takeda 779) is an antagonist of chemokine receptor 5 (CCR5), CCR2b, and CXC chemokine receptor 3 (CXCR3).</p>Formula:C33H39ClN2O2Purity:99.21%Color and Shape:SolidMolecular weight:531.13AMD-070 hydrochloride
CAS:<p>AMD-070 hydrochloride is a CXCR4 antagonist, is useful for Anti HIV.</p>Formula:C21H28ClN5Purity:98.38% - 98.57%Color and Shape:SolidMolecular weight:385.93
