CXCR
CXCRs are a subset of GPCRs that bind to chemokines, small signaling proteins that guide the movement of immune cells towards sites of inflammation, infection, or injury. CXCRs play crucial roles in immune responses, cancer metastasis, and inflammatory diseases. Modulators of CXCRs are being investigated for their potential in treating autoimmune diseases, cancer, and chronic inflammatory conditions. At CymitQuimica, we offer a range of high-quality CXCR modulators to support your research in immunology, oncology, and inflammation.
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WZ811
CAS:55778-02-4
WZ811 is a novel and effective small molecular CXCR4 antagonist (EC50: 0.3 nM).
Formula:
C18H18N4
Purity:
99.58% - ≥95%
Color and Shape:
Solid
Molecular weight:
290.36
Ref: TM-T1739
| 5mg | 34.00 € | ||
| 10mg | 43.00 € | ||
| 25mg | 72.00 € | ||
| 50mg | 106.00 € | ||
| 100mg | 147.00 € | ||
| 200mg | 181.00 € | ||
| 1mL*10mM (DMSO) | 39.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Plerixafor octahydrochloride
CAS:155148-31-5
Plerixafor octahydrochloride mobilizes HSCs by blocking SDF-1alpha/CXCR4 interaction, facilitating their release into circulation.
Formula:
C28H62Cl8N8
Purity:
98.01% - 99.96%
Color and Shape:
Solid
Molecular weight:
794.46
Ref: TM-T1776L
| 5mg | 49.00 € | ||
| 10mg | 63.00 € | ||
| 25mg | 102.00 € | ||
| 50mg | 167.00 € | ||
| 100mg | 303.00 € | ||
| 200mg | 480.00 € | ||
| 500mg | 763.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
MSX-127
CAS:6616-56-4
MSX-127 elicites positive response in peptide CXCR4.
Formula:
C16H24N2O4
Purity:
99.61%
Color and Shape:
Solid
Molecular weight:
308.37
Ref: TM-T4032
| 5mg | 74.00 € | ||
| 10mg | 108.00 € | ||
| 25mg | 185.00 € | ||
| 50mg | 297.00 € | ||
| 100mg | 445.00 € | ||
| 1mL*10mM (DMSO) | 87.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Plerixafor
CAS:110078-46-1
Plerixafor (AMD-3329), a chemokine receptor antagonist, blocks the binding of stromal cell-derived factor (SDF-1alpha) to …
Formula:
C28H54N8
Purity:
100% - ≥95%
Color and Shape:
Solid
Molecular weight:
502.78
Ref: TM-T1776
| 5mg | 49.00 € | ||
| 10mg | 68.00 € | ||
| 25mg | 109.00 € | ||
| 50mg | 172.00 € | ||
| 100mg | 302.00 € | ||
| 200mg | 476.00 € | ||
| 500mg | 763.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Decursin
CAS:5928-25-6
Decursin: potential antiepileptic, hepatoprotective, anti-cancer, anti-amnesic; affects NOX activation, PKCα/MAPK/NF-κB pathways, AChE.
Formula:
C19H20O5
Purity:
100% - 97.22%
Color and Shape:
Solid
Molecular weight:
328.36
Ref: TM-T3S1416
| 1mg | 42.00 € | ||
| 5mg | 86.00 € | ||
| 10mg | 118.00 € | ||
| 25mg | 253.00 € | ||
| 50mg | 453.00 € | ||
| 100mg | 649.00 € | ||
| 500mg | 1,328.00 € | ||
| 1mL*10mM (DMSO) | 87.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
LIT927
CAS:2172879-52-4
LIT927 (LIT-927) is an orally active CXCL12 neutraligand (Ki: 267 nM for CXCL12 binding to …
Formula:
C17H13ClN2O3
Purity:
99.57% - 99.73%
Color and Shape:
Solid
Molecular weight:
328.75
Ref: TM-T5207
| 2mg | 41.00 € | ||
| 5mg | 61.00 € | ||
| 10mg | 96.00 € | ||
| 25mg | 152.00 € | ||
| 50mg | 226.00 € | ||
| 100mg | 330.00 € | ||
| 500mg | 779.00 € | ||
| 1mL*10mM (DMSO) | 68.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
SB-265610
CAS:211096-49-0
SB-265610 (GSK-CXCR2) is a nonpeptide and allosteric CXCR2 antagonist.
Formula:
C14H9BrN6O
Purity:
97.67%
Color and Shape:
Solid
Molecular weight:
357.16
Ref: TM-T16850
| 1mg | 55.00 € | ||
| 5mg | 118.00 € | ||
| 10mg | 184.00 € | ||
| 25mg | 370.00 € | ||
| 50mg | 550.00 € | ||
| 100mg | 786.00 € | ||
| 500mg | 1,612.00 € | ||
| 1mL*10mM (DMSO) | 130.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Danirixin
CAS:954126-98-8
Danirixin (GSK1325756) is a potent antagonist of CXCR2 that inhibits IL-8 binding to CXCR2 (IC50: …
Formula:
C19H21ClFN3O4S
Purity:
100.00% - 99.78%
Color and Shape:
Solid
Molecular weight:
441.9
Ref: TM-T5193
| 1mg | 60.00 € | ||
| 5mg | 109.00 € | ||
| 10mg | 176.00 € | ||
| 25mg | 328.00 € | ||
| 50mg | 522.00 € | ||
| 100mg | 736.00 € | ||
| 1mL*10mM (DMSO) | 133.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Nicotinamide N-oxide
CAS:1986-81-8
Nicotinamide N-oxide, a metabolite of nicotinamide and precursor to NAD+, is reduced by liver enzyme …
Formula:
C6H6N2O2
Purity:
99.61% - 99.9%
Color and Shape:
Solid
Molecular weight:
138.12
Ref: TM-T0617
| 50mg | 39.00 € | ||
| 100mg | 57.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
SB225002
CAS:182498-32-4
SB225002 is a potent and selective CXCR2 antagonist inhibiting interleukin IL-8 binding to CXCR2.
Formula:
C13H10BrN3O4
Purity:
96.86% - 98.79%
Color and Shape:
Solid
Molecular weight:
352.14
Ref: TM-T1955
| 5mg | 50.00 € | ||
| 10mg | 66.00 € | ||
| 25mg | 124.00 € | ||
| 50mg | 220.00 € | ||
| 100mg | 395.00 € | ||
| 200mg | 603.00 € | ||
| 500mg | 922.00 € | ||
| 1mL*10mM (DMSO) | 53.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
AZD-5069
CAS:878385-84-3
AZD-5069 is an chemokine receptor 2 antagonist (CXCR2; IC50 = 0.79 nM).
Formula:
C18H22F2N4O5S2
Purity:
98.53% - 98.85%
Color and Shape:
Solid
Molecular weight:
476.52
Ref: TM-T7681
| 1mg | 50.00 € | ||
| 2mg | 64.00 € | ||
| 5mg | 83.00 € | ||
| 10mg | 122.00 € | ||
| 25mg | 224.00 € | ||
| 50mg | 344.00 € | ||
| 100mg | 513.00 € | ||
| 500mg | 1,111.00 € | ||
| 1mL*10mM (DMSO) | 88.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
SX-682
CAS:1648843-04-2
SX-682 is an orally available allosteric inhibitor of CXCR1 and CXCR2.Cost-effective and quality-assured.
Formula:
C19H14BF4N3O4S
Purity:
98.88% - 99.57%
Color and Shape:
Solid
Molecular weight:
467.2
Ref: TM-T8497
| 1mg | 40.00 € | ||
| 5mg | 87.00 € | ||
| 10mg | 118.00 € | ||
| 25mg | 213.00 € | ||
| 50mg | 353.00 € | ||
| 100mg | 470.00 € | ||
| 1mL*10mM (DMSO) | 87.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
SRT3109
CAS:1204707-71-0
SRT3109 is a CXCR2 ligand used in the treatment of chemokine mediated diseases and conditions.
Formula:
C18H23F2N5O4S2
Purity:
99.65% - 99.92%
Color and Shape:
Solid
Molecular weight:
475.53
Ref: TM-T3047
| 2mg | 41.00 € | ||
| 5mg | 60.00 € | ||
| 10mg | 96.00 € | ||
| 25mg | 170.00 € | ||
| 50mg | 299.00 € | ||
| 1mL*10mM (DMSO) | 64.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Baohuoside I
CAS:113558-15-9
Baohuoside I (Icariside-II) is a component of Epimedium koreanum, exhibits anti-inflammatory activity and anti-osteoporosis activities.
Formula:
C27H30O10
Purity:
97.02% - 98.85%
Color and Shape:
Solid
Molecular weight:
514.52
Ref: TM-T3396
| 1mg | 35.00 € | ||
| 5mg | 75.00 € | ||
| 10mg | 112.00 € | ||
| 25mg | 198.00 € | ||
| 50mg | 339.00 € | ||
| 100mg | 548.00 € | ||
| 500mg | 1,161.00 € | ||
| 1mL*10mM (DMSO) | 129.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Reparixin
CAS:266359-83-5
Reparixin inhibits CXCR1 (IC50=1 nM) strongly, CXCR2 weakly (IC50=100 nM), and it's a CXCL8 receptor …
Formula:
C14H21NO3S
Purity:
98% - 99.89%
Color and Shape:
Solid
Molecular weight:
283.39
Ref: TM-T4163
| 1mg | 52.00 € | ||
| 2mg | 78.00 € | ||
| 5mg | 118.00 € | ||
| 10mg | 183.00 € | ||
| 25mg | 384.00 € | ||
| 50mg | 578.00 € | ||
| 100mg | 817.00 € | ||
| 500mg | 1,626.00 € | ||
| 1mL*10mM (DMSO) | 111.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
TAK-779
CAS:229005-80-5
TAK-779 (Takeda 779) is an antagonist of chemokine receptor 5 (CCR5), CCR2b, and CXC chemokine …
Formula:
C33H39ClN2O2
Purity:
99.21%
Color and Shape:
Solid
Molecular weight:
531.13
Ref: TM-T7499
| 1mg | 45.00 € | ||
| 5mg | 96.00 € | ||
| 10mg | 135.00 € | ||
| 25mg | 235.00 € | ||
| 50mg | 400.00 € | ||
| 100mg | 594.00 € | ||
| 1mL*10mM (DMSO) | 95.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
MSX-130
CAS:4051-59-6
MSX-130 is CXCR4 Antagonist.
Formula:
C36H26N4
Purity:
99.44%
Color and Shape:
Solid
Molecular weight:
514.62
Ref: TM-T4033
| 1mg | 36.00 € | ||
| 5mg | 74.00 € | ||
| 10mg | 110.00 € | ||
| 25mg | 223.00 € | ||
| 50mg | 362.00 € | ||
| 100mg | 580.00 € | ||
| 200mg | 822.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Burixafor hydrobromide
CAS:1191450-19-7
Burixafor hydrobromide is an oral CXCR4 blocker with anti-angiogenic properties, potentially treating choroid neovascularization.
Formula:
C27H52BrN8O3P
Purity:
98%
Color and Shape:
Solid
Molecular weight:
647.644
Ref: TM-T10635
| 25mg | To inquire | ||
| 50mg | To inquire | ||
| 100mg | To inquire |
Estimated delivery in United States, on Wednesday 22 Jan 2025
AZD8797
CAS:911715-90-7
AZD8797 (KAND567) is a CX3CR1 antagonist with potential protective effects against neuronal damage and prevents …
Formula:
C19H25N5OS2
Purity:
98.73% - 99.68%
Color and Shape:
Solid
Molecular weight:
403.56
Ref: TM-T14384
| 1mg | 91.00 € | ||
| 5mg | 184.00 € | ||
| 10mg | 346.00 € | ||
| 25mg | 733.00 € | ||
| 50mg | 918.00 € | ||
| 100mg | 1,329.00 € | ||
| 1mL*10mM (DMSO) | 216.00 € |
Estimated delivery in United States, on Wednesday 22 Jan 2025
SRT3190
CAS:1204707-73-2
SRT3190 is an antagonist of CXCR2.
Formula:
C18H23F2N5O4S2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
475.53
Ref: TM-T16933
| 2mg | 137.00 € | ||
| 5mg | 231.00 € | ||
| 25mg | 619.00 € | ||
| 50mg | 821.00 € | ||
| 100mg | 1,213.00 € | ||
| 1mL*10mM (DMSO) | 402.00 € |
Estimated delivery in United States, on Wednesday 22 Jan 2025
