CXCR
CXCRs are a subset of GPCRs that bind to chemokines, small signaling proteins that guide the movement of immune cells towards sites of inflammation, infection, or injury. CXCRs play crucial roles in immune responses, cancer metastasis, and inflammatory diseases. Modulators of CXCRs are being investigated for their potential in treating autoimmune diseases, cancer, and chronic inflammatory conditions. At CymitQuimica, we offer a range of high-quality CXCR modulators to support your research in immunology, oncology, and inflammation.
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Reparixin L-lysine salt
CAS:266359-93-7
Reparixin L-lysine salt (Repertaxin L-lysine salt) is an allosteric chemokine receptor 1/2 (CXCR1/2) activation inhibitor.
Formula:
C20H35N3O5S
Purity:
99%
Color and Shape:
Solid
Molecular weight:
429.57
Ref: TM-T12705
| 5mg | 46.00 € | ||
| 10mg | 59.00 € | ||
| 25mg | 118.00 € | ||
| 50mg | 185.00 € | ||
| 1mL*10mM (DMSO) | 51.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
VUF11207 fumarate
CAS:1785665-61-3
VUF11207 fumarate is an agonist of CXCR7 and a high-potency ligand of CXCR7 (pKi: 8.1).
Formula:
C31H39FN2O8
Purity:
99.5%
Color and Shape:
Solid
Molecular weight:
586.65
Ref: TM-T13324
| 1mg | 42.00 € | ||
| 2mg | 55.00 € | ||
| 5mg | 87.00 € | ||
| 10mg | 135.00 € | ||
| 25mg | 270.00 € | ||
| 50mg | 467.00 € | ||
| 100mg | 672.00 € | ||
| 200mg | 934.00 € | ||
| 1mL*10mM (DMSO) | 96.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
AMG 487
CAS:473719-41-4
AMG 487: potent CXCR3 antagonist, blocks CXCL10/CXCL11 binding, IC50s: 8.0/8.2 nM.
Formula:
C32H28F3N5O4
Purity:
99.89%
Color and Shape:
Solid
Molecular weight:
603.59
Ref: TM-T10297L
| 1mg | 52.00 € | ||
| 2mg | 75.00 € | ||
| 5mg | 113.00 € | ||
| 10mg | 161.00 € | ||
| 25mg | 262.00 € | ||
| 50mg | 391.00 € | ||
| 100mg | 577.00 € | ||
| 1mL*10mM (DMSO) | 153.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
Delmetacin
CAS:16401-80-2
Delmetacin: a non-steroidal anti-inflammatory drug with analgesic properties, inhibits CXCR1.
Formula:
C18H15NO3
Purity:
99.42%
Color and Shape:
Liquid
Molecular weight:
293.32
Ref: TM-T68052
| 1mg | 81.00 € | ||
| 5mg | 172.00 € | ||
| 10mg | 251.00 € | ||
| 25mg | 472.00 € | ||
| 50mg | 636.00 € | ||
| 100mg | 925.00 € | ||
| 500mg | 1,839.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
ITIC-4F
CAS:2097998-59-7
ITIC-4F: a postfullerene IDTT electron acceptor for high-efficiency PSCs, relevant in binary, ternary, and tandem …
Formula:
C94H78F4N4O2S4
Purity:
98%
Color and Shape:
Solid
Molecular weight:
1499.92
Ref: TM-T19385
| 50mg | To inquire | ||
| 100mg | To inquire |
Estimated delivery in United States, on Thursday 5 Dec 2024
VUF-11222
CAS:1414376-84-3
VUF-11222 is an agonist of high affinity non-peptide CXCR3 agonist (pKi = 7.2).
Formula:
C25H31BrIN
Purity:
99.82%
Color and Shape:
Solid
Molecular weight:
552.33
Ref: TM-T35085
| 1mg | 140.00 € | ||
| 2mg | 187.00 € | ||
| 5mg | 329.00 € | ||
| 10mg | 491.00 € | ||
| 25mg | 796.00 € | ||
| 50mg | 1,095.00 € | ||
| 100mg | 1,482.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
ITIC
CAS:1664293-06-4
"ITIC, a non-fullerene acceptor with high Tg of 180°C, shows excellent thermal stability and a …
Formula:
C94H82N4O2S4
Purity:
98%
Color and Shape:
Solid
Molecular weight:
1427.96
Ref: TM-T19386
| 25mg | 1,435.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
NUCC-390 dihydrochloride (1060524-97-1 free base)
NUCC-390 dihydrochloride is selective agonist of small-molecule CXCR4 receptor.
Formula:
C23H35Cl2N5O
Purity:
98%
Color and Shape:
Solid
Molecular weight:
468.46
Ref: TM-T12269L
| 100mg | To inquire | ||
| 500mg | To inquire |
Estimated delivery in United States, on Thursday 5 Dec 2024
CXCR4-IN-2
CXCR4-IN-2 (compound A1), a potent bifunctional fluorinated small molecule, inhibits CXCR4 and exhibits anticancer properties …
Formula:
C21H20F6N4S
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
474.47
Ref: TM-T78879
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Thursday 5 Dec 2024
CXCL-CXCR1/2-IN-1
CAS:2415653-55-1
CXCL-CXCR1/2-IN-1 is an ELR+CXCL-CXCR1/2 pathway inhibitor with anticancer activity and can be used in the …
Formula:
C14H8Cl2N4O3S
Purity:
99.40%
Color and Shape:
Soild
Molecular weight:
383.21
Ref: TM-T84325
| 5mg | 47.00 € | ||
| 10mg | 69.00 € | ||
| 25mg | 124.00 € | ||
| 50mg | 198.00 € | ||
| 100mg | 295.00 € | ||
| 500mg | 705.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
CXCR7 antagonist-1
CAS:1613021-99-0
CXCR7 antagonist-1 is a specific antagonist of the binding of the SDF-1 chemokine or I-TAC …
Formula:
C21H19FN6O
Purity:
99.51%
Color and Shape:
Liquid
Molecular weight:
390.41
Ref: TM-T39078
| 1mg | 175.00 € | ||
| 5mg | 444.00 € | ||
| 10mg | 643.00 € | ||
| 25mg | 1,003.00 € | ||
| 50mg | 1,380.00 € | ||
| 100mg | 1,831.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
ATI-2341
CAS:1337878-62-2
ATI-2341, pepducin targeting the CXCR4, is an allosteric agonist activating the Gi to promote inhibition …
Formula:
C104H178N26O25S2
Color and Shape:
Solid
Molecular weight:
2256.82
Ref: TM-T6764
| 1mg | 115.00 € | ||
| 2mg | 205.00 € | ||
| 5mg | 371.00 € | ||
| 10mg | 593.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
USL311
CAS:1373268-67-7
USL311 blocks CXCR4/SDF-1 interaction, inhibits tumor cell growth and migration.
Formula:
C24H34N6O
Purity:
99.56% - 99.73%
Color and Shape:
Solid
Molecular weight:
422.57
Ref: TM-T17208
| 1mg | 42.00 € | ||
| 5mg | 88.00 € | ||
| 10mg | 126.00 € | ||
| 25mg | 247.00 € | ||
| 50mg | 388.00 € | ||
| 100mg | 621.00 € | ||
| 500mg | 1,288.00 € | ||
| 1mL*10mM (DMSO) | 87.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
UNBS5162
CAS:956590-23-1
UNBS5162 (UNBS-5162) is a novel naphthalimide that decreases CXCL chemokine expression in experimental prostate cancers.
Formula:
C17H18N4O3
Purity:
98.37% - 99.97%
Color and Shape:
Solid
Molecular weight:
326.35
Ref: TM-T2477
| 1mg | 39.00 € | ||
| 5mg | 81.00 € | ||
| 10mg | 115.00 € | ||
| 25mg | 213.00 € | ||
| 50mg | 336.00 € | ||
| 100mg | 534.00 € | ||
| 200mg | 778.00 € | ||
| 1mL*10mM (DMSO) | 89.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
MSX-122
CAS:897657-95-3
MSX-122 is a novel small molecule and partial CXCR4 antagonist, with potent inhibition of CXCR4/CXCL12 …
Formula:
C16H16N6
Purity:
97.02% - 98.78%
Color and Shape:
Solid
Molecular weight:
292.34
Ref: TM-T3992
| 5mg | 63.00 € | ||
| 10mg | 96.00 € | ||
| 25mg | 186.00 € | ||
| 50mg | 325.00 € | ||
| 100mg | 481.00 € | ||
| 500mg | 1,003.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
AMD 3465 hexahydrobromide
CAS:185991-07-5
AMD 3465 hexahydrobromide (GENZ-644494 (hexahydrobromide)) is a CXCR4 receptor antagonist with potential anticancer and anti-HIV …
Formula:
C24H44Br6N6
Purity:
99.03%
Color and Shape:
Solid
Molecular weight:
896.07
Ref: TM-T7208
| 5mg | 36.00 € | ||
| 10mg | 50.00 € | ||
| 25mg | 90.00 € | ||
| 50mg | 139.00 € | ||
| 100mg | 211.00 € | ||
| 200mg | 314.00 € | ||
| 1mL*10mM (DMSO) | 43.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
ML339
CAS:2579689-83-9
ML339 a selective inhibitor of CXCR6(IC50 = 140 nM) with no response when screened against …
Formula:
C26H32ClN3O5
Purity:
99.46%
Color and Shape:
Solid
Molecular weight:
502
Ref: TM-T9721
| 1mg | 45.00 € | ||
| 5mg | 96.00 € | ||
| 10mg | 142.00 € | ||
| 25mg | 276.00 € | ||
| 50mg | 446.00 € | ||
| 100mg | 640.00 € | ||
| 1mL*10mM (DMSO) | 96.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
AMD-070 hydrochloride
CAS:880549-30-4
AMD-070 hydrochloride is a CXCR4 antagonist, is useful for Anti HIV.
Formula:
C21H28ClN5
Purity:
98.38% - 98.57%
Color and Shape:
Solid
Molecular weight:
385.93
Ref: TM-T22565
| 1mg | 49.00 € | ||
| 2mg | 68.00 € | ||
| 5mg | 92.00 € | ||
| 10mg | 138.00 € | ||
| 25mg | 267.00 € | ||
| 50mg | 400.00 € | ||
| 100mg | 592.00 € | ||
| 1mL*10mM (DMSO) | 104.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Navarixin
CAS:473727-83-2
Navarixin (MK-7123)(SCH527123) is a novel, selective CXC chemokine receptor 2(CXCR2) antagonist that inhibits neutrophil activation …
Formula:
C21H23N3O5
Purity:
98% - 98.63%
Color and Shape:
Solid
Molecular weight:
397.42
Ref: TM-T7130
| 1mg | 40.00 € | ||
| 5mg | 83.00 € | ||
| 10mg | 119.00 € | ||
| 25mg | 207.00 € | ||
| 50mg | 310.00 € | ||
| 100mg | 458.00 € | ||
| 500mg | 1,005.00 € | ||
| 1mL*10mM (DMSO) | 93.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
JMS-17-2
CAS:1380392-05-1
JMS-17-2 is a potent and selective antagonist of CX3CR1( IC50 : 0.32 nM).
Formula:
C25H26ClN3O
Purity:
98.70% - ≥98%
Color and Shape:
Solid
Molecular weight:
419.95
Ref: TM-T5849
| 1mg | 40.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 85.00 € | ||
| 10mg | 128.00 € | ||
| 25mg | 218.00 € | ||
| 50mg | 337.00 € | ||
| 100mg | 500.00 € | ||
| 1mL*10mM (DMSO) | 96.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
