TLR
Toll-like receptors (TLRs) are a class of proteins that play a critical role in the innate immune system by recognizing pathogen-associated molecular patterns (PAMPs) and initiating immune responses. TLRs are involved in detecting a wide range of pathogens, including bacteria, viruses, and fungi, and are essential for the activation of inflammatory signaling pathways. Dysregulation of TLR signaling is associated with chronic inflammatory diseases, autoimmune disorders, and cancer. At CymitQuimica, we offer a variety of high-quality TLR modulators to support your research in innate immunity, inflammation, and infectious disease.
Found 74 products of "TLR"
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C29
CAS:C29 inhibits TLR2/1 and TLR2/6 in human cells, but only TLR2/1 in mouse macrophages.Formula:C16H15NO4Purity:96.34% - 97.37%Color and Shape:SolidMolecular weight:285.29TLR3-IN-1
CAS:TLR3-IN-1 (CU CPT 4a) is a selective TLR3 inhibitor. It can inhibit TLR3/dsRNA complex-mediated downstream signaling pathways and inhibit the TNF-α and IL-1β.Formula:C18H13ClFNO3SPurity:98.56%Color and Shape:SolidMolecular weight:377.82Ref: TM-T22698
1mg52.00€5mg103.00€10mg168.00€25mg353.00€50mg504.00€100mg708.00€1mL*10mM (DMSO)113.00€RS09 2TFA (1449566-36-2 free base)
RS09 2TFA is a TLR4 agonist enhancing NF-κB and cytokines in macrophages; it's an adjuvant that boosts X-15 antibodies.Formula:C35H51F6N9O13Purity:>99.99%Color and Shape:SolidMolecular weight:919.82CU-CPT-9a
CAS:CU-CPT-9a is a potent TLR8 inhibitor (IC50 : 0.5 nM), that suppresses TLR8-mediated proinflammatory signaling in various cell lines and human primary cells-Formula:C17H15NO2Purity:99.01%Color and Shape:SolidMolecular weight:265.31Ref: TM-T7317
1mg38.00€2mg50.00€5mg84.00€10mg119.00€25mg225.00€50mg409.00€100mg605.00€1mL*10mM (DMSO)93.00€TLR7/8/9-IN-1
CAS:TLR7/8/9-IN-1 is a potent inhibitor of Toll-like receptors 7/8/9 (TLR7/8/9) with an IC50 of 43 nM.Formula:C27H37N3O2Purity:99.56%Color and Shape:SolidMolecular weight:435.6Ref: TM-T39669
1mg49.00€2mg70.00€5mg111.00€10mg178.00€25mg290.00€50mg424.00€100mg577.00€200mg825.00€1mL*10mM (DMSO)166.00€Pam3CSK4 TFA (112208-00-1 free base)
CAS:Pam3CSK4 TFA (Pam3Cys-Ser-(Lys)4 TFA) is a Toll-like receptor 1/2 agonist with EC50 of 0.47 ng/mL for human TLR1/2.Cost-effective and quality-assured.
Formula:C87H159F9N10O19SPurity:96.4% - 99.01%Color and Shape:SolidMolecular weight:1852.33TLR4-IN-C34
CAS:TLR4-IN-C34 is an inhibitor of TLR4, and reduces systemic inflammation in models of endotoxemia and necrotizing enterocolitisFormula:C17H27NO9Purity:99.69%Color and Shape:SolidMolecular weight:389.4Bropirimine
CAS:Bropirimine (U-54461) (U-54461) is a biological response modifier that is thought to act through the induction of lymphokines.Formula:C10H8BrN3OPurity:99.01%Color and Shape:SolidMolecular weight:266.091V209
CAS:1V209 (TLR7 agonist T7) is a Toll-like receptor 7 (TLR7) agonist and has anti-tumor effects.Formula:C16H17N5O5Purity:99.61%Color and Shape:SolidMolecular weight:359.34TLR7/8 agonist 1 dihydrochloride
CAS:TLR7/8 agonist 1 dihydrochloride (TLR7/8 agonist-5d) is a TLR7/8 agonist which shows prominent immunostimulatory activities.Formula:C22H27Cl2N5Purity:98.33%Color and Shape:SolidMolecular weight:432.39Ref: TM-T5561
1mg57.00€5mg120.00€10mg187.00€25mg406.00€50mg630.00€100mg898.00€200mg1,216.00€1mL*10mM (DMSO)133.00€Robinin
CAS:Robinin: a kaempferol-derived flavone glycoside with antibacterial, diuretic traits; minimal effect on Colo 320 MDR1/LRP resistance; detected in MCF-7 cells.Formula:C33H40O19Purity:98.78% - 99.13%Color and Shape:SolidMolecular weight:740.66Paridiprubart
CAS:Paridiprubart (NI-0101) is a humanised monoclonal antibody targeting TLR4, ameliorative effects in COVID-19 patients with ARDS and rheumatoid arthritis.Purity:95% - 96.9% (SDS-PAGE); 98.5% (SEC-HPLC)Color and Shape:LiquidMolecular weight:145.16 kDaTLR7 agonist 1
CAS:TLR7 agonist 1 is a selective and oral TLR7 agonist (IC50: 90 nM).Formula:C21H25N5OPurity:98%Color and Shape:SolidMolecular weight:363.46AXC-715 trihydrochloride
CAS:AXC-715 trihydrochloride is a TLR7/8 agonist used to make PD-L1 adjuvanted antibody immunocouplings.Formula:C18H28Cl3N5Purity:99.87%Color and Shape:SolidMolecular weight:420.81CL264
CAS:CL264, a selective agonist of TLR7, can be used in studies about innate immune signals.Formula:C19H23N7O4Purity:98.01% - 99.87%Color and Shape:SolidMolecular weight:413.43Ref: TM-T10833
1mg49.00€5mg110.00€10mg182.00€25mg289.00€50mg399.00€100mg530.00€200mg715.00€1mL*10mM (DMSO)122.00€DSR-6434
CAS:DSR-6434 is a selective agonist of TLR7 with antitumor effect. DSR-6434 exhibits EC50s of 7.2 nM and 4.6 nM for human and mouse.Formula:C19H28N8O2Purity:99.78%Color and Shape:SolidMolecular weight:400.48AZD8848
CAS:AZD8848 is a selective antedrug agonist of toll-like receptor 7 (TLR7). It is developed for the research of asthma and allergic rhinitis.Formula:C29H43N7O5Color and Shape:SolidMolecular weight:569.7TLR7/8-IN-1
CAS:TLR7/8-IN-1, a crystalline TLR7/TLR8 inhibitor, is a valuable compound for autoimmune disease research.Cost-effective and quality-assured.Formula:C29H40N8O2Purity:99.99%Color and Shape:SolidMolecular weight:532.68M62812
CAS:TLR4 inhibitor blocks LPS-induced NF-κB (IC50=2.4μg/mL), cytokines in PBMCs/HUVECs, and extends life in septic shock mice.Formula:C13H13Cl2N3OSPurity:99.07%Color and Shape:SolidMolecular weight:330.23AT791
CAS:AT791 is an orally available TLR7 and TLR9 inhibitor, suppressing TLR7 and TLR9 signaling, used in autoimmune lupus research.Formula:C23H31N3O3Purity:99.88%Color and Shape:SolidMolecular weight:397.51Ref: TM-T61882
1mg72.00€5mg156.00€10mg235.00€25mg378.00€50mg540.00€100mg747.00€200mg1,035.00€1mL*10mM (DMSO)167.00€
