
MALT
Mucosa-associated lymphoid tissue (MALT) is an essential component of the immune system that protects mucosal surfaces from pathogens. MALT includes structures such as the tonsils, Peyer's patches, and the appendix, which are involved in the initiation of immune responses to antigens encountered at mucosal surfaces. Research on MALT is critical for understanding the mechanisms of mucosal immunity and the development of vaccines and treatments for mucosal infections. At CymitQuimica, we provide a range of reagents and tools to support your research in mucosal immunology, inflammation, and infectious diseases.
Found 25 products of "MALT"
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(S)-MALT1-IN-5
CAS:(S)-MALT1-IN-5: Potent MALT1 protease inhibitor, may help in abnormal T/B-cell signalling and MALT1-linked diseases.Formula:C17H17ClF2N6O3Color and Shape:SolidMolecular weight:426.80(S,R,S)-AHPC-Boc derivative 1
CAS:(S,R,S)-AHPC-Boc derivative 1 (Compound 80-9; VH032-Boc derivative 1) is a selective proteasomal degrader targeting MALT1, which recruits the E3 ubiquitin ligase CRBN to form a ternary complex with MALT1. This interaction leads to the ubiquitination and subsequent proteasomal degradation of MALT1. By disrupting the CBM complex, (S,R,S)-AHPC-Boc derivative 1 inhibits the NF-κB signaling pathway and shows potential in inducing apoptosis in ABC-DLBCL cells. It holds promise for research into MALT1-dependent cancers, such as diffuse large B-cell lymphoma (DLBCL).Formula:C28H40N4O6SColor and Shape:SolidMolecular weight:560.705MALT1-IN-11
CAS:MALT1-IN-11: MALT1 inhibitor, IC50 <10-100 nM, reduces IL10, for cancer/autoimmune research.Formula:C20H16F4N8OColor and Shape:SolidMolecular weight:460.39RGT-068A
CAS:RGT-068A is a potent, selective and oral bioavailable MALT1 inhibitor .Formula:C17H16ClN9O2Color and Shape:SolidMolecular weight:413.82Ocipumaltib
CAS:Ocipumaltib (Example 2) is an inhibitor of mucosa-associated lymphoid tissue protein 1 (MALT1). It functions as an antineoplastic agent and is utilized in the study of cancer, infections, neurological disorders, and hematological diseases.Formula:C20H16ClF3N8O2Color and Shape:SolidMolecular weight:492.84
