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MALT

MALT

Mucosa-associated lymphoid tissue (MALT) is an essential component of the immune system that protects mucosal surfaces from pathogens. MALT includes structures such as the tonsils, Peyer's patches, and the appendix, which are involved in the initiation of immune responses to antigens encountered at mucosal surfaces. Research on MALT is critical for understanding the mechanisms of mucosal immunity and the development of vaccines and treatments for mucosal infections. At CymitQuimica, we provide a range of reagents and tools to support your research in mucosal immunology, inflammation, and infectious diseases.

Found 25 products of "MALT"

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  • (S)-MALT1-IN-5

    CAS:
    (S)-MALT1-IN-5: Potent MALT1 protease inhibitor, may help in abnormal T/B-cell signalling and MALT1-linked diseases.
    Formula:C17H17ClF2N6O3
    Color and Shape:Solid
    Molecular weight:426.80

    Ref: TM-T62322

    25mg
    1,927.00€
    50mg
    2,507.00€
    100mg
    3,168.00€
  • (S,R,S)-AHPC-Boc derivative 1

    CAS:
    (S,R,S)-AHPC-Boc derivative 1 (Compound 80-9; VH032-Boc derivative 1) is a selective proteasomal degrader targeting MALT1, which recruits the E3 ubiquitin ligase CRBN to form a ternary complex with MALT1. This interaction leads to the ubiquitination and subsequent proteasomal degradation of MALT1. By disrupting the CBM complex, (S,R,S)-AHPC-Boc derivative 1 inhibits the NF-κB signaling pathway and shows potential in inducing apoptosis in ABC-DLBCL cells. It holds promise for research into MALT1-dependent cancers, such as diffuse large B-cell lymphoma (DLBCL).
    Formula:C28H40N4O6S
    Color and Shape:Solid
    Molecular weight:560.705

    Ref: TM-T206790

    10mg
    To inquire
    50mg
    To inquire
  • MALT1-IN-11

    CAS:
    MALT1-IN-11: MALT1 inhibitor, IC50 <10-100 nM, reduces IL10, for cancer/autoimmune research.
    Formula:C20H16F4N8O
    Color and Shape:Solid
    Molecular weight:460.39

    Ref: TM-T73019

    25mg
    2,583.00€
    50mg
    3,402.00€
    100mg
    4,680.00€
  • RGT-068A

    CAS:
    RGT-068A is a potent, selective and oral bioavailable MALT1 inhibitor .
    Formula:C17H16ClN9O2
    Color and Shape:Solid
    Molecular weight:413.82

    Ref: TM-T73389

    25mg
    2,583.00€
    50mg
    3,402.00€
    100mg
    4,680.00€
  • Ocipumaltib

    CAS:
    Ocipumaltib (Example 2) is an inhibitor of mucosa-associated lymphoid tissue protein 1 (MALT1). It functions as an antineoplastic agent and is utilized in the study of cancer, infections, neurological disorders, and hematological diseases.
    Formula:C20H16ClF3N8O2
    Color and Shape:Solid
    Molecular weight:492.84

    Ref: TM-T211708

    10mg
    To inquire
    50mg
    To inquire