CymitQuimica logo
JAK

JAK

JAK (Janus kinase) inhibitors are compounds that target the JAK-STAT signaling pathway, which is involved in cell growth, immune response, and angiogenesis. By inhibiting JAK, these compounds can reduce the signaling that leads to the formation of new blood vessels in tumors, thereby inhibiting tumor growth. JAK inhibitors are important in the treatment of cancers and inflammatory diseases. At CymitQuimica, we offer a diverse range of high-quality JAK inhibitors to support your research in oncology, immunology, and angiogenesis.

Found 245 products of "JAK"

Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
products per page.
  • Thi-DPPY
    Targetmol
    + Info

    Thi-DPPY

    CAS:
    <p>Thi-DPPY: Potent JAK3/BTK inhibitor (IC50: 1.38/62.4 nM), anti-proliferative, anti-inflammatory, potential in IPF research.</p>
    Formula:C28H28ClN5O4S
    Color and Shape:Solid
    Molecular weight:566.07

    Ref: TM-T64008

  • PF-00956980
    Targetmol
    + Info

    PF-00956980

    CAS:
    <p>PF-00956980: reversible JAK inhibitor, IC50: JAK1 (2.2μM), JAK2 (23.1μM), JAK3 (59.9μM), for lung/skin inflammation research.</p>
    Formula:C18H26N6O
    Color and Shape:Solid
    Molecular weight:342.44

    Ref: TM-T71089

  • SYK/JAK-IN-1
    Targetmol
    + Info

    SYK/JAK-IN-1

    CAS:
    <p>SYK/JAK-IN-1 is a dual SYK/JAK inhibitor with IC50 values of less than 5 nM for both SYK and JAK2.</p>
    Formula:C24H26N8O3
    Color and Shape:Solid
    Molecular weight:474.52

    Ref: TM-T63086

  • JAK3-IN-1
    Targetmol
    + Info

    JAK3-IN-1

    CAS:
    <p>JAK3-IN-1 is an orally active, selective and potent JAK3 inhibitor for the study of immune system disorders.</p>
    Formula:C26H30ClN7O2
    Color and Shape:Solid
    Molecular weight:508.02

    Ref: TM-T15607

  • JAK-IN-10
    Targetmol
    + Info

    JAK-IN-10

    CAS:
    <p>JAK-IN-10 is a JAK inhibitor. JAK-IN-10 can be used for the research of dry eye disorders.</p>
    Formula:C20H18FN5O3S
    Purity:99.53%
    Color and Shape:Solid
    Molecular weight:427.45

    Ref: TM-T13571

  • JAK-IN-28
    Targetmol
    + Info

    JAK-IN-28

    CAS:
    <p>JAK-IN-28 (Compound 111) is a Janus kinase (JAK) inhibitor potentially applicable in the research of cancer and inflammatory diseases [1].</p>
    Formula:C20H18ClN7O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:407.86

    Ref: TM-T79116

  • JAK-IN-30
    Targetmol
    + Info

    JAK-IN-30

    CAS:
    <p>JAK-IN-30 (compound 31) is a water-soluble inhibitor of Janus kinases (JAKs), demonstrating inhibitory potency with half-maximal inhibitory concentration (IC50</p>
    Formula:C19H26N8S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:398.53

    Ref: TM-T79235

  • JAK1-IN-4
    Targetmol
    + Info

    JAK1-IN-4

    CAS:
    <p>JAK1-IN-4 selectively blocks JAK1 (IC50 = 85 nM) over JAK2/JAK3 and halts STAT3 phosphorylation in NCI-H 1975 cells (IC50 = 227 nM).</p>
    Formula:C26H32FN9O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:521.59

    Ref: TM-T15606

  • JAK3/BTK-IN-2
    Targetmol
    + Info

    JAK3/BTK-IN-2

    CAS:
    <p>JAK3/ BTk-in-2 is a potent JAK3/BTK inhibitor.</p>
    Formula:C25H32N8O2
    Purity:99.64% - 99.87%
    Color and Shape:Solid
    Molecular weight:476.57

    Ref: TM-T9813

  • Lorpucitinib
    Targetmol
    + Info

    Lorpucitinib

    CAS:
    <p>Lorpucitinib (JNJ-64251330) is a JAK kinase inhibitor used in the study of inflammatory and gastrointestinal diseases.</p>
    Formula:C22H28N6O2
    Purity:99.72%
    Color and Shape:Solid
    Molecular weight:408.5

    Ref: TM-T62053

  • JAK3i
    Targetmol
    + Info

    JAK3i

    CAS:
    <p>JAK3i selectively inhibits JAK3 kinase, targeting the second, vital wave of STAT5 phosphorylation for T cell growth.</p>
    Formula:C18H15FN4O3
    Purity:98.61% - 99.81%
    Color and Shape:Solid
    Molecular weight:354.34

    Ref: TM-T27650

  • Jaspamycin
    Targetmol
    + Info

    Jaspamycin

    CAS:
    <p>Jaspamycin (7-CN-7-C-Ino) does not bind with purified human PKARIα.</p>
    Formula:C12H12N4O5
    Color and Shape:Solid
    Molecular weight:292.25

    Ref: TM-T11711

  • JAK3/BTK-IN-1
    Targetmol
    + Info

    JAK3/BTK-IN-1

    CAS:
    <p>JAK3/ BTk-in-1 is a dual JAK3/BTK inhibitor that specifically targets and inhibits Janus kinase 3 (JAK3) and Bruton's tyrosine kinase (BTK), two important</p>
    Formula:C25H28N8O
    Purity:97.89%
    Color and Shape:Solid
    Molecular weight:456.54

    Ref: TM-T9814

  • Izencitinib
    Targetmol
    + Info

    Izencitinib

    CAS:
    <p>Izencitinib (JNJ-8398) is a JAK inhibitor with potential anti-inflammatory activity for the study of ulcerative colitis and Crohn;s disease.</p>
    Formula:C22H26N8
    Purity:99.82%
    Color and Shape:Solid
    Molecular weight:402.50

    Ref: TM-T35898

  • STS-E412
    Targetmol
    + Info

    STS-E412

    CAS:
    <p>STS-E412 is a tissue-protective and selective EPOR/CD131 receptor activator for the study of neurological disorders.</p>
    Formula:C15H15ClN4O2
    Purity:99.01%
    Color and Shape:Solid
    Molecular weight:318.76

    Ref: TM-T24840

  • JAK1-IN-8
    Targetmol
    + Info

    JAK1-IN-8

    CAS:
    <p>JAK1-IN-8, a specific inhibitor of Janus kinase 1 (JAK1, IC50&lt;500 nM).</p>
    Formula:C22H23FN4O3S
    Purity:98.4%
    Color and Shape:Solid
    Molecular weight:442.51

    Ref: TM-T35899

  • JAK-STAT-IN-1
    Targetmol
    + Info

    JAK-STAT-IN-1

    CAS:
    <p>JAK-STAT-IN-1 is a specific JAK-STAT inhibitor indicated for the study of autoimmune diseases.</p>
    Formula:C21H21N5O2
    Purity:99.59%
    Color and Shape:Solid
    Molecular weight:375.42

    Ref: TM-T78607

  • Butyzamide
    Targetmol
    + Info

    Butyzamide

    CAS:
    <p>Butyzamide: oral Mpl activator, non-peptide, antagonizes TPO receptors, boosts hMpl, Ba/F3 cells, and enhances platelets in mice.</p>
    Formula:C29H32Cl2N2O5S
    Purity:99.51% - 99.83%
    Color and Shape:Soild
    Molecular weight:591.55

    Ref: TM-T67894

  • JAK-IN-25
    Targetmol
    + Info

    JAK-IN-25

    CAS:
    <p>JAK-IN-25 (compound 19), a potent JAK inhibitor, exhibits IC50 values of 6 nM for TYK2, 21 nM for JAK1, 8 nM for JAK2, and 1051 nM for JAK3.</p>
    Formula:C19H17N5O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:379.37

    Ref: TM-T78175

  • Nezulcitinib
    Targetmol
    + Info

    Nezulcitinib

    CAS:
    <p>Nezulcitinib (TD-0903) is an inhaled pan-JAK inhibitor targeting COVID-19-related acute lung injury.</p>
    Formula:C30H37N7O2
    Color and Shape:Solid
    Molecular weight:527.66

    Ref: TM-T63709