JAK
JAK (Janus kinase) inhibitors are compounds that target the JAK-STAT signaling pathway, which is involved in cell growth, immune response, and angiogenesis. By inhibiting JAK, these compounds can reduce the signaling that leads to the formation of new blood vessels in tumors, thereby inhibiting tumor growth. JAK inhibitors are important in the treatment of cancers and inflammatory diseases. At CymitQuimica, we offer a diverse range of high-quality JAK inhibitors to support your research in oncology, immunology, and angiogenesis.
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JAK1-IN-10
CAS:2416858-88-1
JAK1-IN-10 (compound 9), a cyano-substituted cyclic hydrazine derivative, functions as a potent and selective inhibitor …
Formula:
C15H17N7
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
295.34
Ref: TM-T79078
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 3 Feb 2025
Brepocitinib
CAS:1883299-62-4
Brepocitinib (PF-06700841) is a potent dual JAK1/TYK2 inhibitor (IC50s: 17 nM/23 nM). Brepocitinib also inhibits …
Formula:
C18H21F2N7O
Purity:
98%
Color and Shape:
Solid
Molecular weight:
389.4
Ref: TM-TQ0010
| 1mg | 35.00 € | ||
| 5mg | 69.00 € | ||
| 10mg | 102.00 € | ||
| 25mg | 212.00 € | ||
| 50mg | 383.00 € | ||
| 100mg | 614.00 € | ||
| 200mg | 859.00 € | ||
| 500mg | 1,270.00 € | ||
| 1mL*10mM (DMSO) | 117.00 € |
Estimated delivery in United States, on Monday 3 Feb 2025
QL-1200186
CAS:2848664-42-4
QL-1200186 is an orally active, selective TYK2 inhibitor that, upon dose-dependent oral administration, suppresses interferon-γ …
Formula:
C26H27N7O3
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
485.54
Ref: TM-T81331
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 3 Feb 2025
STAT3-IN-18
CAS:2668267-41-0
STAT3-IN-18 (compound SPP), a platinum (IV) complex featuring an axial ligand from sandalwood, suppresses the …
Formula:
C18H24Cl2N2O6Pt
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
630.38
Ref: TM-T79609
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 3 Feb 2025
JAK-IN-34
CAS:2068766-90-3
JAK-IN-34 (compound 11n) is a potent inhibitor of Janus kinases (JAKs), demonstrating IC50 values of …
Formula:
C27H26N6O
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
450.53
Ref: TM-T82017
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 3 Feb 2025
JAK-IN-3
CAS:1400876-94-9
JAK-IN-3 is a potent JAK inhibitor that inhibits JAK3, JAK1, TYK2, and JAK2, and can …
Formula:
C18H20N4O3
Purity:
98.04% - 98.04%
Color and Shape:
Solid
Molecular weight:
340.38
Ref: TM-T11704
| 1mg | 176.00 € | ||
| 25mg | 1,688.00 € | ||
| 50mg | 2,228.00 € | ||
| 100mg | 2,902.00 € |
Estimated delivery in United States, on Monday 3 Feb 2025
JAK-IN-5
CAS:2096999-92-5
JAK-IN-5 is a JAK inhibitor.
Formula:
C27H31FN6O
Purity:
97.78% - 98.78%
Color and Shape:
Solid
Molecular weight:
474.57
Ref: TM-T11710
| 1mg | 183.00 € | ||
| 5mg | 385.00 € | ||
| 10mg | 570.00 € | ||
| 25mg | 907.00 € | ||
| 50mg | 1,230.00 € | ||
| 100mg | 1,660.00 € | ||
| 500mg | 3,316.00 € | ||
| 1mL*10mM (DMSO) | 564.00 € |
Estimated delivery in United States, on Monday 3 Feb 2025
JAK-IN-31
CAS:2597016-88-9
JAK-IN-31 (Example 75), a JAK inhibitor, demonstrates IC50 values of ≤0.01 µM for JAK1, ≤0.01 …
Formula:
C21H19N7O2S2
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
465.55
Ref: TM-T79882
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 3 Feb 2025
JAK kinase-IN-1
CAS:2698389-43-2
JAK kinase-IN-1 (Example 1) functions as a potent inhibitor targeting the JAK family, which includes …
Formula:
C17H19F2N7OS
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
407.44
Ref: TM-T79807
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 3 Feb 2025
Lepzacitinib
CAS:2321488-47-3
Lepzacitinib, a Janus kinase inhibitor, specifically targets JAK 1/3.
Formula:
C18H21N5O3
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
355.39
Ref: TM-T78207
| 2mg | 91.00 € |
Estimated delivery in United States, on Monday 3 Feb 2025
JAK1-IN-11
CAS:2427608-43-1
JAK1-IN-11 (compound 11) serves as a potent inhibitor of Janus kinases, exhibiting nanomolar inhibitory concentrations …
Formula:
C26H36N6O4S
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
528.67
Ref: TM-T79079
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 3 Feb 2025
ABBV-712
CAS:2368945-27-9
ABBV-712 is a selective Tyrosine Kinase 2 (TYK2) inhibitor, demonstrating an IC50 value of 0.195 …
Formula:
C24H28N4O5
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
452.5
Ref: TM-T83218
| 5mg | 1,354.00 € | ||
| 10mg | 1,824.00 € | ||
| 25mg | 2,435.00 € | ||
| 50mg | 3,070.00 € |
Estimated delivery in United States, on Monday 3 Feb 2025
CP-352664
CAS:1097883-05-0
CP-352664 is a JAK inhibitor with potency against JAK3, exhibiting an EC50 value of 210 …
Formula:
C18H18N4
Color and Shape:
Liquid
Molecular weight:
290.36
Ref: TM-T200202
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 3 Mar 2025
AJI-214
CAS:1395886-20-0
AJI-214 functions as a dual-target inhibitor that specifically blocks Aurora kinase A and JAK2. By …
Formula:
C17H13ClFN5O
Color and Shape:
Liquid
Molecular weight:
357.77
Ref: TM-T200387
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 3 Mar 2025
JDTic dihydrochloride
CAS:785835-79-2
JDTic is a powerful antagonist of kappa-opioid receptors (KOR), effectively inhibiting the antinociceptive effects induced …
Formula:
C28H41Cl2N3O3
Purity:
98%
Color and Shape:
Solid
Molecular weight:
538.55
Ref: TM-T11721L
| 2mg | 102.00 € | ||
| 25mg | 620.00 € | ||
| 50mg | 813.00 € | ||
| 100mg | 1,208.00 € |
Estimated delivery in United States, on Monday 3 Mar 2025
MM-589 TFA
CAS:2097887-21-1
MM-589 TFA is a potent WD repeat domain 5 (WDR5)inhibitor and mixed lineage leukemia (MLL) …
Formula:
C30H45F3N8O7
Purity:
98%
Color and Shape:
Solid
Molecular weight:
686.72
Ref: TM-T12091L
| 25mg | 2,801.00 € | ||
| 50mg | 3,720.00 € | ||
| 100mg | 5,140.00 € |
Estimated delivery in United States, on Monday 3 Mar 2025
MM-589
CAS:2097887-20-0
MM-589 is a potent WD repeat domain 5 (WDR5) inhibitor and mixed lineage leukemia (MLL) …
Formula:
C28H44N8O5
Purity:
98%
Color and Shape:
Solid
Molecular weight:
572.7
Ref: TM-T12091
| 25mg | 2,801.00 € | ||
| 50mg | 3,722.00 € | ||
| 100mg | 5,144.00 € |
Estimated delivery in United States, on Monday 3 Mar 2025
ITK inhibitor 2
CAS:1309784-09-5
ITK inhibitor 2 is a interleukin-2-inducible T-cell kinase (ITK) inhibitor , with an IC50 of …
Formula:
C25H33N5O2
Color and Shape:
Solid
Molecular weight:
435.56
Ref: TM-T11690
| 50mg | 738.00 € | ||
| 100mg | 1,105.00 € |
Estimated delivery in United States, on Monday 3 Mar 2025
Londamocitinib
CAS:2241039-81-4
Londamocitinib (JAK1-IN-7) is a selective and potent JAK1 inhibitor with anti-inflammatory activity.
Formula:
C28H31F2N7O4S
Purity:
99.47%
Color and Shape:
Solid
Molecular weight:
599.65
Ref: TM-T11706
| 1mg | 176.00 € | ||
| 5mg | 430.00 € | ||
| 10mg | 584.00 € | ||
| 25mg | 884.00 € | ||
| 50mg | 1,141.00 € | ||
| 100mg | 1,531.00 € | ||
| 1mL*10mM (DMSO) | 554.00 € |
Estimated delivery in United States, on Monday 3 Mar 2025
AZ-3
CAS:2228908-91-4
AZ-3 is a potent and selective JAK1 inhibitor (IC50: 34 nM).
Formula:
C20H28FN7
Purity:
98%
Color and Shape:
Solid
Molecular weight:
385.48
Ref: TM-T10424
| 25mg | 2,384.00 € | ||
| 50mg | 3,159.00 € | ||
| 100mg | 4,299.00 € |
Estimated delivery in United States, on Monday 3 Mar 2025
