JAK
JAK (Janus kinase) inhibitors are compounds that target the JAK-STAT signaling pathway, which is involved in cell growth, immune response, and angiogenesis. By inhibiting JAK, these compounds can reduce the signaling that leads to the formation of new blood vessels in tumors, thereby inhibiting tumor growth. JAK inhibitors are important in the treatment of cancers and inflammatory diseases. At CymitQuimica, we offer a diverse range of high-quality JAK inhibitors to support your research in oncology, immunology, and angiogenesis.
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SHR0302
CAS:1445987-21-2
SHR0302 (ARQ252) is a JAK inhibitor that binds JAK1 with stronger affinity than others (Selectivity …
Formula:
C18H22N8O2S
Purity:
99.11%
Color and Shape:
Solid
Molecular weight:
414.48
Ref: TM-T9195
| 1mg | 157.00 € | ||
| 5mg | 384.00 € | ||
| 10mg | 606.00 € | ||
| 25mg | 1,012.00 € | ||
| 50mg | 1,447.00 € | ||
| 100mg | 1,837.00 € | ||
| 1mL*10mM (DMSO) | 445.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
AG490
CAS:133550-30-8
AG490 inhibits EGFR (0.1 μM IC50), 135x >selective than ErbB2, blocks JAK2, spares Lyn, Lck, …
Formula:
C17H14N2O3
Purity:
98.6% - 99.7%
Color and Shape:
Yellow Solid
Molecular weight:
294.3
Ref: TM-T2600
| 10mg | 55.00 € | ||
| 25mg | 74.00 € | ||
| 50mg | 90.00 € | ||
| 100mg | 100.00 € | ||
| 200mg | 162.00 € | ||
| 500mg | 278.00 € | ||
| 1mL*10mM (DMSO) | 53.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Fedratinib hydrochloride hydrate
CAS:1374744-69-0
Fedratinib hydrochloride hydrate (SAR 302503 hydrochloride hydrate) is a potent, selective, ATP-competitive and orally active …
Formula:
C27H40Cl2N6O4S
Purity:
98.96%
Color and Shape:
Solid
Molecular weight:
615.61
Ref: TM-T9251
| 5mg | 46.00 € | ||
| 10mg | 60.00 € | ||
| 25mg | 84.00 € | ||
| 50mg | 98.00 € | ||
| 100mg | 118.00 € | ||
| 200mg | 184.00 € | ||
| 1mL*10mM (DMSO) | 67.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
BMS-911543
CAS:1271022-90-2
BMS-911543 is a potent and selective inhibitor of JAK2 with IC50 of 1.1 nM, ~350-, …
Formula:
C23H28N8O
Purity:
97.69% - 99.98%
Color and Shape:
Solid
Molecular weight:
432.52
Ref: TM-T6790
| 1mg | 56.00 € | ||
| 2mg | 78.00 € | ||
| 5mg | 114.00 € | ||
| 10mg | 181.00 € | ||
| 25mg | 372.00 € | ||
| 50mg | 557.00 € | ||
| 1mL*10mM (DMSO) | 110.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
FM-381
CAS:2226521-65-7
FM381, a JAK3 inhibitor with 127 pM IC50, is 410-3600x more selective over JAK1/2/TYK2.
Formula:
C24H24N6O2
Purity:
99.33%
Color and Shape:
Solid
Molecular weight:
428.49
Ref: TM-T5091
| 1mg | 52.00 € | ||
| 5mg | 110.00 € | ||
| 10mg | 157.00 € | ||
| 25mg | 315.00 € | ||
| 50mg | 458.00 € | ||
| 100mg | 672.00 € | ||
| 1mL*10mM (DMSO) | 123.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
TG101209
CAS:936091-14-4
TG101209 is a selective JAK2 inhibitor with IC50 of 6 nM.
Formula:
C26H35N7O2S
Purity:
100% - 99%
Color and Shape:
Solid
Molecular weight:
509.67
Ref: TM-T3065
| 2mg | 47.00 € | ||
| 5mg | 66.00 € | ||
| 10mg | 92.00 € | ||
| 25mg | 104.00 € | ||
| 50mg | 122.00 € | ||
| 100mg | 193.00 € | ||
| 1mL*10mM (DMSO) | 73.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
RO495
CAS:1258296-60-4
RO495 (CS-2667), a potent inhibitor of TYK2, inhibits TYK2 with IC50 of 1.5nM as tested …
Formula:
C17H14Cl2N6O
Purity:
99.4%
Color and Shape:
Solid
Molecular weight:
389.24
Ref: TM-T22416
| 1mg | 61.00 € | ||
| 2mg | 83.00 € | ||
| 5mg | 112.00 € | ||
| 10mg | 176.00 € | ||
| 25mg | 340.00 € | ||
| 50mg | 499.00 € | ||
| 100mg | 672.00 € | ||
| 200mg | 904.00 € | ||
| 1mL*10mM (DMSO) | 135.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Curculigoside
CAS:85643-19-2
1.
Formula:
C22H26O11
Purity:
99.85%
Color and Shape:
Solid
Molecular weight:
466.44
Ref: TM-T6S1966
| 1mg | 46.00 € | ||
| 5mg | 69.00 € | ||
| 10mg | 94.00 € | ||
| 25mg | 156.00 € | ||
| 50mg | 221.00 € | ||
| 100mg | 333.00 € | ||
| 1mL*10mM (DMSO) | 71.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Pacritinib
CAS:937272-79-2
Pacritinib (SB1518) (SB1518) is an effective and specific inhibitor of JAK2 and FLT3 (IC50: 23/22 …
Formula:
C28H32N4O3
Purity:
99.27% - ≥95%
Color and Shape:
Solid
Molecular weight:
472.58
Ref: TM-T6020
| 2mg | 40.00 € | ||
| 5mg | 59.00 € | ||
| 10mg | 96.00 € | ||
| 25mg | 148.00 € | ||
| 50mg | 222.00 € | ||
| 100mg | 368.00 € | ||
| 500mg | 866.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Fedratinib
CAS:936091-26-8
Fedratinib (TG-101348) (TG101348) is an ATP-competitive inhibitor of JAK2 (IC50: 3 nM) with significantly less …
Formula:
C27H36N6O3S
Purity:
98.23% - 99.96%
Color and Shape:
Solid
Molecular weight:
524.68
Ref: TM-T1995
| 1g | 613.00 € | ||
| 5mg | 49.00 € | ||
| 10mg | 68.00 € | ||
| 50mg | 111.00 € | ||
| 100mg | 132.00 € | ||
| 200mg | 213.00 € | ||
| 500mg | 463.00 € | ||
| 1mL*10mM (DMSO) | 57.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Ruxolitinib (S enantiomer)
CAS:941685-37-6
Ruxolitinib S enantiomer (INCB18424) is the S-enantiomer of Ruxolitinib. Ruxolitinib is the first potent, selective …
Formula:
C17H18N6
Purity:
99.5% - 99.79%
Color and Shape:
Solid
Molecular weight:
306.36
Ref: TM-T6156
| 5mg | 63.00 € | ||
| 10mg | 74.00 € | ||
| 50mg | 113.00 € | ||
| 100mg | 151.00 € | ||
| 1mL*10mM (DMSO) | 64.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
SC99
CAS:882290-02-0
SC99 inhibits JAK2-STAT3, reducing STAT3 genes, platelet activity, and has anti-myeloma, anti-thrombotic effects.
Formula:
C15H8Cl2FN3O
Purity:
99.56%
Color and Shape:
Solid
Molecular weight:
336.15
Ref: TM-T8719
| 1mg | 44.00 € | ||
| 5mg | 90.00 € | ||
| 10mg | 136.00 € | ||
| 25mg | 232.00 € | ||
| 50mg | 350.00 € | ||
| 100mg | 436.00 € | ||
| 200mg | 608.00 € | ||
| 1mL*10mM (DMSO) | 96.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Cucurbitacin I
CAS:2222-07-3
Cucurbitacin I (JSI-124), a natural compound, is a selective inhibitor of JAK2/STAT3 with anti-cancer activity.
Formula:
C30H42O7
Purity:
96.69% - 98.2%
Color and Shape:
Solid
Molecular weight:
514.65
Ref: TM-TQ0196
| 1mg | 83.00 € | ||
| 5mg | 172.00 € | ||
| 10mg | 222.00 € | ||
| 25mg | 367.00 € | ||
| 50mg | 546.00 € | ||
| 1mL*10mM (DMSO) | 184.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
![WDR5-0103 hydrochloride[890190-22-4(free base)]](https://static.cymitquimica.com/products/TM/thumb/T5140.jpg)
WDR5-0103 hydrochloride[890190-22-4(free base)]
WDR5-0103 hydrochloride[890190-22-4(free base)] (WD-Repeat Protein 5-0103) is an effective and specific WD repeat-containing protein 5 …
Formula:
C21H26ClN3O4
Purity:
99.81%
Color and Shape:
Solid
Molecular weight:
419.9
Ref: TM-T5140
| 2mg | 35.00 € | ||
| 5mg | 46.00 € | ||
| 10mg | 78.00 € | ||
| 25mg | 124.00 € | ||
| 50mg | 208.00 € | ||
| 100mg | 261.00 € | ||
| 200mg | 382.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Tofacitinib Citrate
CAS:540737-29-9
Tofacitinib Citrate (CP-690550 citrate) is a a potent, cell-permeable inhibitor of JAK1/2/3 (IC50s: 1/20/112 nM).
Formula:
C22H28N6O8
Purity:
99.19% - 99.75%
Color and Shape:
Solid
Molecular weight:
504.49
Ref: TM-T2398
| 5mg | 38.00 € | ||
| 10mg | 54.00 € | ||
| 50mg | 69.00 € | ||
| 100mg | 90.00 € | ||
| 200mg | 124.00 € | ||
| 500mg | 204.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
SAR-20347
CAS:1450881-55-6
SAR-20347 is an inhibitor of TYK2, JAK1/2/3 (IC50: 0.6/23/26/41 nM).
Formula:
C21H18ClFN4O4
Purity:
99.35% - 99.77%
Color and Shape:
Solid
Molecular weight:
444.84
Ref: TM-T4210
| 1mg | 36.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 113.00 € | ||
| 25mg | 221.00 € | ||
| 50mg | 344.00 € | ||
| 100mg | 573.00 € | ||
| 200mg | 808.00 € | ||
| 1mL*10mM (DMSO) | 86.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Ruxolitinib phosphate
CAS:1092939-17-7
Ruxolitinib phosphate (INCB18424 phosphate) is a JAK1/2 inhibitor with IC50 of 3.3 nM/2.8 nM. Cost-effective …
Formula:
C17H21N6O4P
Purity:
100% - 99.91%
Color and Shape:
Solid
Molecular weight:
404.36
Ref: TM-T3043
| 1g | 604.00 € | ||
| 5mg | 52.00 € | ||
| 10mg | 64.00 € | ||
| 25mg | 81.00 € | ||
| 50mg | 95.00 € | ||
| 100mg | 144.00 € | ||
| 200mg | 223.00 € | ||
| 500mg | 408.00 € | ||
| 1mL*10mM (DMSO) | 59.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
GLPG0634 analog
CAS:1206101-20-3
GLPG0634 analog (GLPG0634 analogue) is a specific JAK1 inhibitor with IC50 of 10/28/810/116 nM for …
Formula:
C23H18N6O2
Purity:
100% - 99.22%
Color and Shape:
Solid
Molecular weight:
410.43
Ref: TM-T3076
| 1mg | 40.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 87.00 € | ||
| 10mg | 143.00 € | ||
| 25mg | 260.00 € | ||
| 50mg | 460.00 € | ||
| 100mg | 650.00 € | ||
| 500mg | 1,352.00 € | ||
| 1mL*10mM (DMSO) | 87.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
RO8191
CAS:691868-88-9
RO8191 (CDM-3008) (CDM-3008) is an agonist of interferon (IFN) receptor.
Formula:
C14H5F6N5O
Purity:
98.85% - ≥98%
Color and Shape:
Solid
Molecular weight:
373.21
Ref: TM-T22142
| 1mg | 45.00 € | ||
| 2mg | 58.00 € | ||
| 5mg | 96.00 € | ||
| 10mg | 142.00 € | ||
| 25mg | 301.00 € | ||
| 50mg | 478.00 € | ||
| 100mg | 698.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
ZM39923 hydrochloride
CAS:1021868-92-7
ZM39923 hydrochloride (JAK3 Inhibitor IV) is an JAK1/3 inhibitor, almost no activity to JAK2 and …
Formula:
C23H25NO·HCl
Purity:
98.05%
Color and Shape:
Solid
Molecular weight:
367.91
Ref: TM-T6145
| 5mg | 58.00 € | ||
| 10mg | 93.00 € | ||
| 25mg | 168.00 € | ||
| 50mg | 304.00 € | ||
| 100mg | 455.00 € | ||
| 1mL*10mM (DMSO) | 95.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
