JAK
JAK (Janus kinase) inhibitors are compounds that target the JAK-STAT signaling pathway, which is involved in cell growth, immune response, and angiogenesis. By inhibiting JAK, these compounds can reduce the signaling that leads to the formation of new blood vessels in tumors, thereby inhibiting tumor growth. JAK inhibitors are important in the treatment of cancers and inflammatory diseases. At CymitQuimica, we offer a diverse range of high-quality JAK inhibitors to support your research in oncology, immunology, and angiogenesis.
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Momelotinib Mesylate
CAS:1056636-07-7
Momelotinib Mesylate is an ATP-competitive JAK1/JAK2 inhibitor (IC50: 11 nM/18 nM). It has 10-fold selectivity …
Formula:
C24H26N6O5S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
510.57
Ref: TM-T15037
| 25mg | 1,410.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
JAK3/BTK-IN-2
CAS:2674036-93-0
JAK3/ BTk-in-2 is a potent JAK3/BTK inhibitor.
Formula:
C25H32N8O2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
476.57
Ref: TM-T9813
| 25mg | 1,234.00 € | ||
| 50mg | 1,605.00 € | ||
| 100mg | 2,419.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
JAK3/BTK-IN-1
CAS:2674036-91-8
JAK3/ BTk-in-1 is a dual JAK3/BTK inhibitor that specifically targets and inhibits Janus kinase 3 …
Formula:
C25H28N8O
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
456.54
Ref: TM-T9814
| 1mg | 225.00 € | ||
| 5mg | 560.00 € | ||
| 10mg | 797.00 € | ||
| 25mg | 1,234.00 € | ||
| 50mg | 1,561.00 € | ||
| 100mg | 2,350.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
Lorpucitinib
CAS:2230282-02-5
Lorpucitinib (JNJ-64251330) is a JAK kinase inhibitor used in the study of inflammatory and gastrointestinal …
Formula:
C22H28N6O2
Purity:
99.72%
Color and Shape:
Liquid
Molecular weight:
408.5
Ref: TM-T62053
| 1mg | 212.00 € | ||
| 5mg | 531.00 € | ||
| 10mg | 848.00 € | ||
| 25mg | 1,606.00 € | ||
| 50mg | 2,589.00 € | ||
| 100mg | 3,498.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
Izencitinib
CAS:2051918-33-1
Izencitinib (JNJ-8398) is a JAK inhibitor with potential anti-inflammatory activity for the study of ulcerative …
Formula:
C22H26N8
Purity:
99.82%
Color and Shape:
Liquid
Molecular weight:
402.50
Ref: TM-T35898
| 1mg | 88.00 € | ||
| 5mg | 185.00 € | ||
| 10mg | 294.00 € | ||
| 25mg | 590.00 € | ||
| 50mg | 925.00 € | ||
| 100mg | 1,490.00 € | ||
| 200mg | 2,042.00 € | ||
| 1mL*10mM (DMSO) | 204.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
JAK3i
CAS:1918238-72-8
JAK3i selectively inhibits JAK3 kinase, targeting the second, vital wave of STAT5 phosphorylation for T …
Formula:
C18H15FN4O3
Purity:
98.61% - 99.81%
Color and Shape:
Solid
Molecular weight:
354.34
Ref: TM-T27650
| 1mg | 326.00 € | ||
| 5mg | 769.00 € | ||
| 10mg | 1,050.00 € | ||
| 25mg | 1,476.00 € | ||
| 50mg | 1,850.00 € | ||
| 1mL*10mM (DMSO) | 658.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
JAK-IN-11
CAS:916742-11-5
JAK-IN-11 (R-348) is a potent and selective inhibitor of JAK, has the potential for the …
Formula:
C23H22FN5O4S
Purity:
99.57%
Color and Shape:
Solid
Molecular weight:
483.52
Ref: TM-T12549
| 1mg | 273.00 € | ||
| 5mg | 547.00 € | ||
| 10mg | 890.00 € | ||
| 25mg | 1,620.00 € | ||
| 50mg | 2,177.00 € | ||
| 1mL*10mM (DMSO) | 621.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
JAK1-IN-8
CAS:1973485-18-5
JAK1-IN-8, a specific inhibitor of Janus kinase 1 (JAK1, IC50<500 nM).
Formula:
C22H23FN4O3S
Purity:
98.36%
Color and Shape:
Liquid
Molecular weight:
442.51
Ref: TM-T35899
| 5mg | 46.00 € | ||
| 10mg | 80.00 € | ||
| 25mg | 145.00 € | ||
| 50mg | 251.00 € | ||
| 100mg | 426.00 € | ||
| 200mg | 569.00 € | ||
| 1mL*10mM (DMSO) | 52.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
Jaspamycin
CAS:22242-96-2
Jaspamycin (7-CN-7-C-Ino) does not bind with purified human PKARIα.
Formula:
C12H12N4O5
Color and Shape:
Solid
Molecular weight:
292.25
Ref: TM-T11711
| 5mg | 278.00 € | ||
| 25mg | 916.00 € | ||
| 50mg | 1,273.00 € | ||
| 100mg | 1,741.00 € | ||
| 1mL*10mM (DMSO) | 301.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
SD-1029
CAS:118372-34-2
SD-1029 is a JAK2 inhibitor and a novel Stat3 activation inhibitor that inhibits Stat3 phosphorylation …
Formula:
C25H32Br2Cl2N2O3
Color and Shape:
Solid
Molecular weight:
639.25
Ref: TM-T24774
| 1mg | 89.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
JBJ-04-125-02
CAS:2060610-53-7
JBJ-04-125-02: Oral EGFR inhibitor, targets EGFRL858R/T790M with 0.26 nM IC50, halts cancer growth, anti-tumor.
Formula:
C29H26FN5O3S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
543.61
Ref: TM-T11714
| 25mg | 1,406.00 € | ||
| 50mg | 1,851.00 € | ||
| 100mg | 2,337.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
JAK-IN-10
CAS:916741-98-5
JAK-IN-10 is a JAK inhibitor. JAK-IN-10 can be used for the research of dry eye …
Formula:
C20H18FN5O3S
Purity:
98.88%
Color and Shape:
Solid
Molecular weight:
427.45
Ref: TM-T13571
| 1mg | 85.00 € | ||
| 5mg | 174.00 € | ||
| 10mg | 255.00 € | ||
| 25mg | 420.00 € | ||
| 50mg | 592.00 € | ||
| 100mg | 799.00 € | ||
| 500mg | 1,591.00 € | ||
| 1mL*10mM (DMSO) | 187.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
JAK-IN-28
CAS:2445500-22-9
JAK-IN-28 (Compound 111) is a Janus kinase (JAK) inhibitor potentially applicable in the research of …
Formula:
C20H18ClN7O
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
407.86
Ref: TM-T79116
| 25mg | 1,410.00 € | ||
| 50mg | 1,851.00 € | ||
| 100mg | 2,337.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
JAK-IN-27
CAS:2673176-36-6
JAK-IN-27, also known as compound 1, is an orally active, potent inhibitor of the JAKS …
Formula:
C20H21F2N7O
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
413.42
Ref: TM-T79110
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 3 Feb 2025
JAK2-IN-4
CAS:1438284-00-4
JAK2-IN-4 is a selective JAK2/JAK3 inhibitor, with IC50 values of 0.7 nM and 23.2 nM …
Formula:
C23H27N5O4S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
469.56
Ref: TM-T11708
| 25mg | 1,827.00 € | ||
| 50mg | 2,413.00 € | ||
| 100mg | 3,180.00 € |
Estimated delivery in United States, on Monday 3 Feb 2025
JAK-IN-25
CAS:2127110-22-7
JAK-IN-25 (compound 19), a potent JAK inhibitor, exhibits IC50 values of 6 nM for TYK2, …
Formula:
C19H17N5O4
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
379.37
Ref: TM-T78175
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 3 Feb 2025
Ginsenoside Rk1
CAS:494753-69-4
Ginsenoside Rk1 is a component created by processing the ginseng plant at high temperatures.
Formula:
C42H70O12
Purity:
99.13%
Color and Shape:
Solid
Molecular weight:
767
Ref: TM-T4S1499
| 5mg | 91.00 € |
Estimated delivery in United States, on Monday 3 Feb 2025
TCS 21311
CAS:1260181-14-3
TCS 21311 (NIBR3049) selectively inhibits JAK3 (IC50: 8 nM) and PKCα/θ & GSK3β; >100x selective …
Formula:
C27H25F3N4O4
Purity:
≥98%
Color and Shape:
Solid
Molecular weight:
526.51
Ref: TM-T17019
| 1mg | 96.00 € |
Estimated delivery in United States, on Monday 3 Feb 2025
JAK-IN-26
CAS:2417134-93-9
JAK-IN-26 (compound 2) is an orally active inhibitor of the Janus kinase (JAK) enzyme with …
Formula:
C22H24N6O3
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
420.46
Ref: TM-T78189
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 3 Feb 2025
DPP
CAS:2668267-47-6
DPP, a Platinum(IV) complex with a pterostilbene-derived axial ligand, inhibits the JAK2-STAT3 pathway in breast …
Formula:
C36H40Cl2N2O10Pt
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
926.7
Ref: TM-T79608
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 3 Feb 2025
