MAPK
MAPKs are a family of protein kinases involved in a variety of cellular processes, including growth, proliferation, differentiation, and stress responses. The MAPK signaling pathway consists of several tiers, including ERK, JNK, and p38 MAPKs, each playing distinct roles in cellular function. Dysregulation of MAPK signaling is linked to cancer, inflammatory diseases, and metabolic disorders. At CymitQuimica, we offer a wide array of MAPK inhibitors and activators to support your research in cell biology, signal transduction, and disease mechanisms.
Found 881 products of "MAPK"
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K-Ras-IN-1
CAS:<p>K-Ras-IN-1 is a K-Ras inhibitor.</p>Formula:C11H13NOSPurity:98.72%Color and Shape:SolidMolecular weight:207.29JNK-IN-8
CAS:<p>JNK-IN-8 (JNK Inhibitor XVI) is an irreversible JNK1/2/4 inhibitor (IC50: 4.7/18.7/1 nM).</p>Formula:C29H29N7O2Purity:99.24% - >99.99%Color and Shape:SolidMolecular weight:507.59Neflamapimod
CAS:<p>Neflamapimod (VX-745) , a specific and effective inhibitor of p38α(IC50=10 nM), is 22-fold greater specificity against p38β and no inhibition activity to p38γ.</p>Formula:C19H9Cl2F2N3OSPurity:97.88% - 99.75%Color and Shape:SolidMolecular weight:436.26SB 239063
CAS:<p>SB 239063 (SB239063) is a potent and selective p38 MAPKα/β inhibitor with IC50 of 44 nM, showing no activity against the γ- and δ-kinase isoforms.</p>Formula:C20H21FN4O2Purity:99.42% - 99.81%Color and Shape:SolidMolecular weight:368.4KRPEP-2D acetate
<p>KRPEP-2D acetate: inhibitor targeting K-Ras(G12D) mutant, a crucial cancer-related protein.</p>Formula:C110H186N44O27S2Purity:98.94%Color and Shape:SolidMolecular weight:2621.06I-49 free base
I-49 free base (Pyrido[4,3-d]pyrimidin-7(6H)-one, 2-methyl-4-[[(1R)-1-[2-methyl-3-(trifluoromethyl)phenyl]ethyl]amino]-6-(tetrahydro-2H-pyran-4-yl)-) is a novelFormula:C23H26ClF3N4O2Purity:99.64% - 99.88%Color and Shape:SolidMolecular weight:482.92PH-797804
CAS:<p>PH-797804 is a pyridinone inhibitor of p38α (IC50: 26 nM, in a cell-free assay); 4-fold more selective versus p38β and does not inhibit JNK2.</p>Formula:C22H19BrF2N2O3Purity:97.90% - 98.27%Color and Shape:SolidMolecular weight:477.3SUN11602
CAS:<p>SUN11602, an aniline compound, mimics the neuroprotective mechanisms of basic fibroblast growth factor.</p>Formula:C26H37N5O2Purity:99.36%Color and Shape:SolidMolecular weight:451.66H05 (TFA)
CAS:<p>6H05 TFA (6H05 trifluoroacetate) is a selective, and allosteric oncogenic mutant K-Ras(G12C) inhibitor.</p>Formula:C22H31ClF3N3O4S3Purity:98.83%Color and Shape:SolidMolecular weight:590.14ML-098
CAS:<p>ML-098 (CID-7345532) is an activator of the GTP-binding protein Rab7 (EC50: 77.6 nM).</p>Formula:C19H19NO3Purity:99.06% - 99.23%Color and Shape:SolidMolecular weight:309.36IACS-13909
CAS:<p>IACS-13909 (BBP-398), a specific and potent allosteric inhibitor of SHP2, that suppresses signaling through the MAPK pathway.</p>Formula:C17H18Cl2N6Purity:98.8%Color and Shape:SolidMolecular weight:377.271-(4-methansulfinylphenyl)ethanone
CAS:<p>The compound inhibits Ras function and therefore inhibits the abnormal growth of cells.</p>Formula:C9H10O2SPurity:99.48%Color and Shape:SolidMolecular weight:182.24CC-90001
CAS:<p>CC-90001 is an orally administered c-Jun N-terminal kinase (JNK) inhibitor with bias for JNK1 over JNK2.</p>Formula:C16H27N5O2Purity:99.96%Color and Shape:SolidMolecular weight:321.42CMPD1
CAS:<p>CMPD1 is a non-ATP-competitive p38 MAPK-mediated MK2 phosphorylation inhibitor(apparent Ki (Kiapp): 330 nM).</p>Formula:C22H20FNO2Purity:99.8%Color and Shape:SolidMolecular weight:349.4L-779450
CAS:L-779450, an effective, ATP-competitive Raf kinase inhibitor (IC50: 10 nM) , displays >7, >30 and >70-fold selectivity over p38α, GSK3β and Lck respectively.Formula:C20H14ClN3OPurity:≥95%Color and Shape:SolidMolecular weight:347.8MK2-IN-3
CAS:<p>MK2-IN-3 is a potent MK-2 inhibitor, cell-permeable, for rheumatoid arthritis treatment.</p>Formula:C21H16N4OPurity:99.01%Color and Shape:SolidMolecular weight:340.38SD 0006
CAS:<p>SD 0006 (SD-06) is a MAPK p38 alpha inhibitor( IC50 : 110 nM) for the treatment of arthritis.</p>Formula:C20H20ClN5O2Purity:98.32%Color and Shape:SolidMolecular weight:397.86TAK-632
CAS:<p>TAK-632 is a potent pan-Raf inhibitor.</p>Formula:C27H18F4N4O3SPurity:98% - 99.5%Color and Shape:SolidMolecular weight:554.52TAK-715
CAS:<p>TAK-715 is a p38 MAPK inhibitor for p38α.</p>Formula:C24H21N3OSPurity:99.83%Color and Shape:SolidMolecular weight:399.51Encorafenib
CAS:Encorafenib (LGX818) is an orally available mutated BRaf V600E inhibitor(IC50=0.3 nM) with potential antineoplastic activity.Formula:C22H27ClFN7O4SPurity:99.51% - 99.83%Color and Shape:SolidMolecular weight:540.01
