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MLK

MLK

MLKs are a group of kinases that can activate multiple MAPK pathways, including JNK and p38, by phosphorylating upstream MAP kinase kinases (MAP2Ks). MLKs are involved in cellular responses to stress, apoptosis, and neuroinflammation. Dysregulation of MLK activity is associated with neurodegenerative diseases and certain cancers. At CymitQuimica, we offer a range of high-quality MLK modulators to support your research in neurobiology, stress response, and signal transduction.

Found 22 products of "MLK"

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  • MBA-m1
    Targetmol
    + Info

    MBA-m1

    CAS:
    <p>MBA-m1 is an MLKL inhibitor that suppresses necroptosis in Mlkl−/−NIH-3T3 cells. Additionally, MBA-m1 alleviates disease conditions in mouse models of dermatitis and abdominal aortic aneurysm induced by MLKL.</p>
    Formula:C27H21ClN2O2
    Color and Shape:Solid
    Molecular weight:440.92

    Ref: TM-T207139

  • MLK-IN-1
    Targetmol
    + Info

    MLK-IN-1

    CAS:
    <p>MLK-IN-1 (US20140256733A1, compound 68) is a highly potent and selective inhibitor of mixed lineage kinase 3 (MLK-3). It exhibits excellent brain penetration and specifically targets MLK-3.</p>
    Formula:C23H20N4O3S
    Color and Shape:Solid
    Molecular weight:432.5

    Ref: TM-T39102

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    Discontinued
    Discontinued product