Ras
Ras proteins are small GTPases that act as molecular switches in the MAPK signaling pathway, controlling cell growth, differentiation, and survival. Activated Ras initiates a signaling cascade that includes Raf, MEK, and ERK, leading to various cellular responses. Mutations in Ras genes are common in cancers, making Ras an important focus of cancer research. At CymitQuimica, we offer a range of Ras modulators to support your research in cancer biology, signal transduction, and therapeutic development.
Found 155 products of "Ras"
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KRASG12C IN-14
<p>KRASG12C IN-14 (compound 15), a potent inhibitor specifically designed for the KRAS G12C mutation, exhibits impressive efficacy in impeding CYPA-dependent KRAS-BRAF interaction and ERK phosphorylation in NCI-H358 cells, both with an IC 50 of 0.002 μM.</p>Formula:C51H65F4N9O9S2Color and Shape:SolidMolecular weight:1088.24MRTF-A-IN-1
<p>MRTF-A-IN-1 (compound 14) is an inhibitor of MRTF-A. It effectively suppresses cell proliferation and induces senescence in HCC cells.</p>Formula:C22H21N3Color and Shape:SolidMolecular weight:327.42BI1701963
<p>BI1701963 is an orally effective inhibitor that targets the SOS1 and KRAS interaction, specifically inhibiting the activation of KRAS by blocking its GTP loading. This compound is utilized in cancer research to explore potential therapeutic effects against KRAS-driven malignancies.</p>Formula:C47H62N8O4SColor and Shape:SolidMolecular weight:835.11Rapaprutug
CAS:<p>Rapaprutug is a monoclonal antibody that targets human KARS1 (lysyl-tRNA synthetase 1). It can block inflammation-related signaling pathways involving KARS1, thereby reducing the production and release of inflammatory factors. Rapaprutug shows potential for research into inflammatory diseases.</p>Color and Shape:LiquidKRAS inhibitor-33
<p>KRAS inhibitor-33 (compound 115a) is a pyrido[2,3-d]pyrimidine derivative that serves as an effective inhibitor of KRAS, exhibiting an IC50 value of ≤ 100nM.</p>Formula:C33H39ClF2N6O3Color and Shape:SolidMolecular weight:641.15KRpep-2d
CAS:<p>KRpep-2d, a potent inhibitor of K-Ras, effectively suppresses the proliferation of cancer cells driven by K-Ras.</p>Formula:C109H183N43O25S2Color and Shape:SolidMolecular weight:2560.02KRAS G12D inhibitor 20
<p>KRAS G12D inhibitor 20 (Compound 14) is a selective G12D KRAS inhibitor with antitumor activity.</p>Formula:C18H26N6OMolecular weight:342.21681ADT-007
CAS:<p>ADT-007 is a pan-RAS inhibitor with potent anticancer activity.</p>Formula:C26H24FNO5Purity:97.75%Color and Shape:SoildMolecular weight:449.47KRpep-2d TFA
<p>KRpep-2d (TFA) is a potent inhibitor of K-Ras, effectively hindering the proliferation of K-Ras-driven cancer cells, thereby serving as a valuable asset for</p>Formula:C110H183F3N44O27S2Color and Shape:SolidMolecular weight:2675.03MC 976
CAS:<p>MC 976 is a derivative of Vitamin D3.</p>Formula:C27H42O3Purity:98%Color and Shape:SolidMolecular weight:414.63GGTI298 Trifluoroacetate
CAS:<p>GGTI298 trifluoroacetate (GGTI298TFA salt) is a geranylgeranyltransferase I inhibitor that causes cell cycle arrest and induces apoptosis.</p>Formula:C27H33N3O3S·C2HF3O2Purity:98.07% - >99.99%Color and Shape:SolidMolecular weight:593.66Ras Inhibitory Peptide acetate
<p>Ras Inhibitory Peptide acetate, involved in cancer-related Ras signaling.</p>Formula:C55H95N19O13Purity:96.63%Color and Shape:SolidMolecular weight:1230.46pan-KRAS-IN-10
<p>Pan-KRAS-IN-10 (Compound 58) acts as an inhibitor of the human tumor mutant gene KRAS. It suppresses the proliferation of KRAS mutant cells, specifically AsPC-1 (G12D mutant) and SW480 (G12V mutant), with IC50 values of 0.7 and 0.24 nM, respectively.</p>Formula:C45H57N7O5SMolecular weight:807.41419G12 TFA
<p>G12 (Ras5-17) TFA is a wild-type Ras peptide comprising amino acids 5-17 (KLVVVGAGGVGKS). It serves as a control in studies involving mutant Ras peptides, such as V12.</p>Formula:C54H96F3N15O17Molecular weight:1283.70607KRAS inhibitor-38
CAS:<p>KRAS Inhibitor-38 (Example 18) is a potent inhibitor capable of effectively suppressing the activity of KRAS G12C, KRAS G12D, and KRAS G12V in vivo.</p>Formula:C53H68ClF2N9O8SColor and Shape:SolidMolecular weight:1064.68Pan-RAS-IN-7
CAS:<p>Pan-RAS-IN-7 (Compound D101) is a broad-spectrum RAS inhibitor used in the synthesis of antibody-drug conjugates (ADCs). It is also applicable in cancer research.</p>Formula:C59H76N8O8Color and Shape:SolidMolecular weight:1025.28Sevelamer Carbonate
CAS:<p>Sevelamer carbonate, a non-absorbed polymer, binds phosphate with carbonate instead of chloride.</p>Formula:(C3H7N·C3H5ClO)x·xCH2O3Purity:98%Color and Shape:SolidMolecular weight:211.64Rasarfin
CAS:<p>Rasarfin inhibits Ras and ARF6.</p>Formula:C23H24ClN3O3Purity:97.98%Color and Shape:SolidMolecular weight:425.91K-Ras(G12C) inhibitor 12
CAS:<p>K-Ras(G12C) inhibitor 12 is an allosteric inhibitor of oncogenic K-Ras(G12C).</p>Formula:C15H17ClIN3O3Purity:97.16%Color and Shape:SolidMolecular weight:449.67(Rac)-Antineoplaston A10
CAS:<p>Antineoplaston A10 is the first identified human antineoplaston, naturally occurring with anti-proliferative properties.</p>Formula:C13H14N2O3Purity:98.41%Color and Shape:SolidMolecular weight:246.26
