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Ras

Ras

Ras proteins are small GTPases that act as molecular switches in the MAPK signaling pathway, controlling cell growth, differentiation, and survival. Activated Ras initiates a signaling cascade that includes Raf, MEK, and ERK, leading to various cellular responses. Mutations in Ras genes are common in cancers, making Ras an important focus of cancer research. At CymitQuimica, we offer a range of Ras modulators to support your research in cancer biology, signal transduction, and therapeutic development.

Found 155 products of "Ras"

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  • MLS000532223
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    MLS000532223

    CAS:
    <p>MLS000532223 is a selectiveRho family GTPases inhibitor(EC50 : 16 μM to 120 μM).</p>
    Formula:C15H9NO3
    Purity:98.6%
    Color and Shape:Solid
    Molecular weight:251.24

    Ref: TM-T8473

  • K-Ras(G12C) inhibitor 9
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    K-Ras(G12C) inhibitor 9

    CAS:
    <p>K-Ras(G12C) inhibitor 9 is an allosteric inhibitor of oncogenic K-Ras(G12C).</p>
    Formula:C16H21ClIN3O4S
    Purity:97.33% - 97.45%
    Color and Shape:Solid
    Molecular weight:513.78

    Ref: TM-T6556

  • ARS-853
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    ARS-853

    CAS:
    <p>ARS-853 is an inhibitor of K-RASG12C(IC50 : 2.5 μM), a mutant form of K-RAS that accumulates in the active GTP-bound state in certain cancer cells</p>
    Formula:C22H29ClN4O3
    Purity:97.43% - 98.4%
    Color and Shape:Solid
    Molecular weight:432.94

    Ref: TM-T7414

  • Antineoplaston A10
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    Antineoplaston A10

    CAS:
    <p>Antineoplaston A10 (NSC-648539) is a Ras inhibitor potentially for the treatment of glioma, lymphoma, astrocytoma and breast cancer.</p>
    Formula:C13H14N2O3
    Purity:99.42%
    Color and Shape:Solid
    Molecular weight:246.26

    Ref: TM-T7131

  • ZCL278
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    ZCL278

    CAS:
    <p>ZCL278 is a selective Cdc42 GTPase inhibitor.</p>
    Formula:C21H19BrClN5O4S2
    Purity:96.29% - 99.72%
    Color and Shape:Solid
    Molecular weight:584.89

    Ref: TM-T1855

  • EHop-016
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    EHop-016

    CAS:
    <p>EHop-016 is a specific Rac GTPase inhibitor with IC50 of 1.1 μM for Rac1 in MDA-MB-231 and MDA-MB-435 cells, equally effective inhibition for Rac3.</p>
    Formula:C25H30N6O
    Purity:98.99% - >99.99%
    Color and Shape:Solid
    Molecular weight:430.55

    Ref: TM-T2427

  • Phellodendrine chloride
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    Phellodendrine chloride

    CAS:
    <p>Phellodendrine chloride combats kidney inflammation by blocking macrophage and T cell activity in glomeruli.</p>
    Formula:C20H24ClNO4
    Purity:98.85% - 99.05%
    Color and Shape:Solid
    Molecular weight:377.86

    Ref: TM-T5S0777

  • Y16
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    Y16

    CAS:
    <p>Y16 is a G protein-coupled Rho GEFs inhibitor and also a specific inhibitor of LARG with a Kd of 76 nM.Cost-effective and quality-assured.</p>
    Formula:C24H20N2O3
    Purity:98.26% - 99.32%
    Color and Shape:Solid
    Molecular weight:384.43

    Ref: TM-T3553

  • CID-1067700
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    CID-1067700

    CAS:
    <p>CID-1067700 is one of the first identified competitive inhibitors of nucleotide binding by Ras-related GTPases（Rab7 with a Ki of 13 nM).</p>
    Formula:C18H18N2O4S2
    Purity:99.46%
    Color and Shape:Solid
    Molecular weight:390.48

    Ref: TM-T7558

  • FTI-277 hydrochloride
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    FTI-277 hydrochloride

    CAS:
    <p>FTI-277 HCl: potent FTase inhibitor, IC50 500 pM, 100x more selective than GGTase I.</p>
    Formula:C22H30ClN3O3S2
    Purity:97.57% - 97.61%
    Color and Shape:Solid
    Molecular weight:484.07

    Ref: TM-T2700

  • CCG-100602
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    CCG-100602

    CAS:
    <p>CCG-100602 inhibits RhoA/C-mediated, SRF-driven luciferase expression in PC-3 prostate cancer cells (IC50 :9.8 μM).</p>
    Formula:C21H17ClF6N2O2
    Purity:99.58%
    Color and Shape:Solid
    Molecular weight:478.82

    Ref: TM-T22062

  • ARS-1620
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    ARS-1620

    CAS:
    <p>ARS-1620 is a covalent inhibitor of K-RASG12C.</p>
    Formula:C21H17ClF2N4O2
    Purity:98.86%
    Color and Shape:Solid
    Molecular weight:430.84

    Ref: TM-T7609

  • (S)-AMG-510
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    (S)-AMG-510

    CAS:
    <p>(S)-AMG-510 is the S-type compound of AMG-510 (Sotorasib), which effectively and selectively inhibits KRASG12C.Cost-effective and quality-assured.</p>
    Formula:C30H30F2N6O3
    Purity:99.05% - 99.76%
    Color and Shape:Solid
    Molecular weight:560.594

    Ref: TM-T22258

  • BAY-293
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    BAY-293

    CAS:
    <p>BAY-293 is a potent, cell-active SOS1 inhibitor that disrupts the KRAS-SOS1 interaction (IC50: 21 nM).</p>
    Formula:C25H28N4O2S
    Purity:97.16%
    Color and Shape:Solid
    Molecular weight:448.58

    Ref: TM-T5418

  • ZT-12-037-01
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    ZT-12-037-01

    CAS:
    <p>Zt-12-037-01 is a ATP competitive STK19 inhibitor（IC50 values of 23.96 nM and 27.94 nM for STK19 (WT) and STK19 (D89N),respectively).</p>
    Formula:C21H31N5O2
    Purity:99.56%
    Color and Shape:Solid
    Molecular weight:385.5

    Ref: TM-T5597

  • SCH54292
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    SCH54292

    CAS:
    <p>SCH-54292 is a GDP exchange inhibitor.</p>
    Formula:C24H28N2O9S
    Purity:95.65%
    Color and Shape:Solid
    Molecular weight:520.55

    Ref: TM-T9198

  • APS6-45
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    APS6-45

    CAS:
    <p>APS6-45 inhibits RAS/MAPK signaling and exhibits anti-tumor activity.</p>
    Formula:C23H16F8N4O3
    Purity:99.39%
    Color and Shape:Solid
    Molecular weight:548.39

    Ref: TM-T8843

  • RBC8
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    RBC8

    CAS:
    <p>RBC8 is a specific GTPases RalA/RalB inhibitor by inhibiting the binding of Ral to its effector RALBP1, no inhibition on the GTPases RhoA and Ras.</p>
    Formula:C25H20N4O3
    Purity:98.44% - 99.81%
    Color and Shape:Solid
    Molecular weight:424.45

    Ref: TM-T6634

  • ML141
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    ML141

    CAS:
    <p>ML141 (CID-2950007) is an effective, specific and reversible non-competitive inhibitor of Rho family GTPase cdc42 (IC50: 200 nM).</p>
    Formula:C22H21N3O3S
    Purity:99.36% - 99.56%
    Color and Shape:Solid
    Molecular weight:407.49

    Ref: TM-T2463

  • 1A-116
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    1A-116

    CAS:
    <p>1A-116 is a specific Rac1 inhibitor.</p>
    Formula:C16H16F3N3
    Purity:99.71%
    Color and Shape:Solid
    Molecular weight:307.31

    Ref: TM-T14004