CAS 71203-35-5

Formula: C22H21N3O3S

InChI: InChI=1S/C22H21N3O3S/c1-28-19-11-7-17(8-12-19)22-15-21(16-5-3-2-4-6-16)24-25(22)18-9-13-20(14-10-18)29(23,26)27/h2-14,22H,15H2,1H3,(H2,23,26,27)

InChI key: QBNZBMVRFYREHK-UHFFFAOYSA-N

SMILES: COC1=CC=C(C=C1)C2CC(=NN2C3=CC=C(C=C3)S(=O)(=O)N)C4=CC=CC=C4

ML141

CAS: 71203-35-5

ML141

Formula: C₂₂H₂₁N₃O₃S

Purity: ≥98%

Molecular weight: 407.49

Ref: 54-BUP07931

ML141

CAS: 71203-35-5

Formula: C₂₂H₂₁N₃O₃S

Purity: 98%

Color and Shape: Solid

Molecular weight: 407.4854

Ref: IN-DA00FC1N

ML141

CAS: 71203-35-5

4-(5-(4-Methoxyphenyl)-3-phenyl-4,5-dihydro-1H-pyrazol-1-yl)benzenesulfonamide

Formula: C₂₂H₂₁N₃O₃S

Purity: 98%

Molecular weight: 407.49

Ref: IN-DG335141

ML141

CAS: 71203-35-5

ML141 (CID-2950007) is an effective, specific and reversible non-competitive inhibitor of Rho family GTPase cdc42 (IC50: 200 nM).

Formula: C₂₂H₂₁N₃O₃S

Purity: 99.36% - 99.56%

Color and Shape: Solid

Molecular weight: 407.485

Ref: TM-T2463

4-(5-(4-Methoxyphenyl)-3-phenyl-4,5-dihydro-1H-pyrazol-1-yl)benzenesulfonamide

CAS: 71203-35-5

Purity: 98%

Molecular weight: 407.4899902

Ref: 10-F869651

ML141

Controlled Product

CAS: 71203-35-5

Applications ML141 is a potent selective reversible non-competitive inhibitor of Rho family GTPase use in the treatment of bacterial infections.
References Hong, L. et al.: J. Biol. Chem., 288, 8531 (2013)

Formula: C₂₂H₂₁N₃O₃S

Color and Shape: Neat

Molecular weight: 407.485

Ref: TR-M425250

Cdc42/Rac1 GTPase Inhibitor, ML141

CAS: 71203-35-5

Cdc42/Rac1 GTPase Inhibitor, ML141, is a small molecule inhibitor, which is a synthetic compound specifically designed to interfere with cellular processes. Originating from high-throughput screening and medicinal chemistry optimization, this inhibitor functions by selectively targeting the Rho family of GTPases, specifically Cdc42 and Rac1. These GTPases play crucial roles in regulating the actin cytoskeleton, cell movement, and growth signaling pathways.

Formula: C₂₂H₂₁N₃O₃S

Purity: Min. 95%

Molecular weight: 407.49 g/mol

Ref: 3D-WCA20335