Ras
Ras proteins are small GTPases that act as molecular switches in the MAPK signaling pathway, controlling cell growth, differentiation, and survival. Activated Ras initiates a signaling cascade that includes Raf, MEK, and ERK, leading to various cellular responses. Mutations in Ras genes are common in cancers, making Ras an important focus of cancer research. At CymitQuimica, we offer a range of Ras modulators to support your research in cancer biology, signal transduction, and therapeutic development.
Found 155 products of "Ras"
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Adagrasib
CAS:View and buy Adagrasib (MRTX849) from TargetMol.MRTX849 is a potent, selective and covalent KRASG12C inhibitor with potential antineoplastic activity. Cited in 2 publications.Formula:C32H35ClFN7O2Purity:99.10% - 99.9%Color and Shape:SolidMolecular weight:604.12MLS000532223
CAS:MLS000532223 is a selectiveRho family GTPases inhibitor(EC50 : 16 μM to 120 μM).Formula:C15H9NO3Purity:98.6%Color and Shape:SolidMolecular weight:251.24Ref: TM-T8473
1mg105.00€5mg250.00€1mL*10mM (DMSO)301.00€10mg401.00€25mg685.00€50mg982.00€100mg1,341.00€MRTX1133
CAS:View and buy MRTX1133 from TargetMol.MRTX1133 is a potent, selective, and noncovalent inhibitor of KRAS G12D.Formula:C33H31F3N6O2Purity:97.39% - 99.6%Color and Shape:SolidMolecular weight:600.63Ref: TM-T9303
1mg177.00€5mg379.00€1mL*10mM (DMSO)502.00€10mg580.00€25mg893.00€50mg1,251.00€100mg1,639.00€200mg2,215.00€ML-097
CAS:ML-097 (CID-2160985) is a pan activator of Ras-related GTPasesFormula:C14H11BrO3Purity:99.12%Color and Shape:SolidMolecular weight:307.139Ref: TM-T21970
5mg62.00€1mL*10mM (DMSO)67.00€10mg90.00€25mg133.00€50mg192.00€100mg286.00€500mg687.00€ZCL278
CAS:ZCL278 is a selective Cdc42 GTPase inhibitor.Formula:C21H19BrClN5O4S2Purity:96.29% - 99.72%Color and Shape:SolidMolecular weight:584.89Ref: TM-T1855
5mg52.00€10mg74.00€1mL*10mM (DMSO)74.00€25mg129.00€50mg210.00€100mg294.00€200mg470.00€500mg763.00€EHop-016
CAS:EHop-016 is a specific Rac GTPase inhibitor with IC50 of 1.1 μM for Rac1 in MDA-MB-231 and MDA-MB-435 cells, equally effective inhibition for Rac3.Formula:C25H30N6OPurity:98.99% - >99.99%Color and Shape:SolidMolecular weight:430.55Ref: TM-T2427
5mg46.00€1mL*10mM (DMSO)49.00€10mg70.00€25mg120.00€50mg202.00€100mg316.00€200mg467.00€500mg747.00€1-(4-methansulfinylphenyl)ethanone
CAS:The compound inhibits Ras function and therefore inhibits the abnormal growth of cells.Formula:C9H10O2SPurity:99.48%Color and Shape:SolidMolecular weight:182.24Ref: TM-T8870
1mg49.00€1mL*10mM (DMSO)96.00€5mg144.00€10mg195.00€25mg273.00€50mg383.00€100mg532.00€200mg718.00€ARS-853
CAS:ARS-853 is an inhibitor of K-RASG12C(IC50 : 2.5 μM), a mutant form of K-RAS that accumulates in the active GTP-bound state in certain cancer cellsFormula:C22H29ClN4O3Purity:97.43% - 98.4%Color and Shape:SolidMolecular weight:432.94Ref: TM-T7414
1mg142.00€1mL*10mM (DMSO)338.00€5mg353.00€10mg525.00€25mg843.00€50mg1,144.00€100mg1,549.00€500mg3,087.00€ML-098
CAS:ML-098 (CID-7345532) is an activator of the GTP-binding protein Rab7 (EC50: 77.6 nM).Formula:C19H19NO3Purity:99.06% - 99.23%Color and Shape:SolidMolecular weight:309.36Ref: TM-T4619
1mg37.00€2mg50.00€5mg66.00€1mL*10mM (DMSO)84.00€10mg94.00€25mg190.00€50mg268.00€100mg374.00€500mg884.00€Antineoplaston A10
CAS:Antineoplaston A10 (NSC-648539) is a Ras inhibitor potentially for the treatment of glioma, lymphoma, astrocytoma and breast cancer.Formula:C13H14N2O3Purity:99.42%Color and Shape:SolidMolecular weight:246.26Ref: TM-T7131
2mg44.00€5mg67.00€1mL*10mM (DMSO)73.00€10mg103.00€25mg193.00€50mg295.00€100mg425.00€200mg595.00€Lonafarnib
CAS:Lonafarnib (Sch66336) is an orally bioavailable FPTase inhibitor for H-ras, K-ras-4B, and N-ras (IC50: 1.9/5.2/2.8 nM).Formula:C27H31Br2ClN4O2Purity:98% - 99.94%Color and Shape:SolidMolecular weight:638.82Phellodendrine chloride
CAS:Phellodendrine chloride combats kidney inflammation by blocking macrophage and T cell activity in glomeruli.Formula:C20H24ClNO4Purity:98.85% - 99.05%Color and Shape:SolidMolecular weight:377.86Ref: TM-T5S0777
5mg50.00€1mL*10mM (DMSO)58.00€10mg71.00€25mg101.00€50mg150.00€100mg215.00€200mg318.00€Y16
CAS:Y16 is a G protein-coupled Rho GEFs inhibitor and also a specific inhibitor of LARG with a Kd of 76 nM.Cost-effective and quality-assured.Formula:C24H20N2O3Purity:98.26% - 99.85%Color and Shape:SolidMolecular weight:384.43Ref: TM-T3553
1mg34.00€2mg48.00€5mg70.00€1mL*10mM (DMSO)77.00€10mg109.00€25mg177.00€50mg263.00€100mg389.00€NSC 23766 trihydrochloride
CAS:NSC 23766 trihydrochloride (Rac1 Inhibitor) is an inhibitor of Rac GTPase targeting Rac activation by GEFs; no inhibitory for RhoA or Cdc42.Formula:C24H35N7·3HClPurity:96.48% - 99.54%Color and Shape:SolidMolecular weight:530.96CID-1067700
CAS:CID-1067700 is one of the first identified competitive inhibitors of nucleotide binding by Ras-related GTPases（Rab7 with a Ki of 13 nM).Formula:C18H18N2O4S2Purity:99.46%Color and Shape:SolidMolecular weight:390.48Ref: TM-T7558
1mg34.00€2mg49.00€5mg71.00€1mL*10mM (DMSO)78.00€10mg105.00€25mg178.00€50mg234.00€100mg303.00€Oncrasin-1
CAS:Oncrasin 1 is a potent inhibitor of anticancer that kills various human lung cancer cells with K-Ras mutations at low or submicromolar concentrationsFormula:C16H12ClNOPurity:99.75%Color and Shape:SolidMolecular weight:269.73MLS-573151
CAS:MLS-573151 is a selective inhibitor of GTPase Cdc42(EC50 of 2 μM).Formula:C21H19N3O2SPurity:98.80%Color and Shape:SolidMolecular weight:377.46Ref: TM-T22106
2mg34.00€5mg50.00€1mL*10mM (DMSO)55.00€10mg86.00€25mg161.00€50mg245.00€100mg363.00€200mg515.00€CCG-222740
CAS:CCG-222740 is an inhibitor of Rho/MRTF pathwayFormula:C23H19ClF2N2O3Purity:98.76%Color and Shape:SolidMolecular weight:444.86Ref: TM-T7764
2mg39.00€5mg62.00€1mL*10mM (DMSO)66.00€10mg94.00€25mg172.00€50mg260.00€100mg371.00€200mg530.00€Salirasib
CAS:Salirasib: Competitive PPMTase inhibitor, blocks Ras methylation, potential cancer treatment, Ki=2.6 μM.Formula:C22H30O2SPurity:99.45%Color and Shape:SolidMolecular weight:358.54Ref: TM-T6163
5mg34.00€10mg50.00€1mL*10mM (DMSO)56.00€25mg90.00€50mg150.00€100mg210.00€200mg344.00€500mg567.00€CCG-100602
CAS:CCG-100602 inhibits RhoA/C-mediated, SRF-driven luciferase expression in PC-3 prostate cancer cells (IC50 :9.8 μM).Formula:C21H17ClF6N2O2Purity:99.58%Color and Shape:SolidMolecular weight:478.82Ref: TM-T22062
5mg35.00€1mL*10mM (DMSO)40.00€10mg54.00€25mg108.00€50mg178.00€100mg286.00€200mg425.00€Kobe2602
CAS:Kobe 2602 is an inhibitor of Ras that exhibits anticancer chemotherapeutic activities.Formula:C14H9F4N5O4SPurity:98.36% - 99.39%Color and Shape:SolidMolecular weight:419.31Arglabin
CAS:Arglabin ((+)-Arglabin) is a natural product isolated from Artemisia glabella, is a NLRP3 inflammasome inhibitor, has anti-atherogenic and anticancer effects.Formula:C15H18O3Purity:98.97% - 99.62%Color and Shape:SolidMolecular weight:246.3Ref: TM-TQ0165
1mg84.00€2mg123.00€5mg227.00€1mL*10mM (DMSO)294.00€10mg341.00€25mg492.00€50mg655.00€100mg982.00€200mg1,314.00€CCG-203971
CAS:CCG-203971 is an inhibitor of SRE activation in the prostate cancer cell line PC-3 (IC50: 6.4 μM), with 87% inhibition of SRE activation achieved at 100 μM.Formula:C23H21ClN2O3Purity:98.82% - 99.50%Color and Shape:SolidMolecular weight:408.88ML141
CAS:ML141 (CID-2950007) is an effective, specific and reversible non-competitive inhibitor of Rho family GTPase cdc42 (IC50: 200 nM).Formula:C22H21N3O3SPurity:99.36% - 99.56%Color and Shape:SolidMolecular weight:407.49Ref: TM-T2463
1mg37.00€2mg52.00€5mg69.00€1mL*10mM (DMSO)71.00€10mg101.00€25mg200.00€50mg321.00€100mg515.00€ARS-1620
CAS:ARS-1620 is a covalent inhibitor of K-RASG12C.Formula:C21H17ClF2N4O2Purity:98.86%Color and Shape:SolidMolecular weight:430.84Rasarfin
CAS:Rasarfin inhibits Ras and ARF6.Formula:C23H24ClN3O3Purity:97.98%Color and Shape:SolidMolecular weight:425.91Ref: TM-T9407
1mg38.00€5mg75.00€1mL*10mM (DMSO)84.00€10mg110.00€25mg193.00€50mg323.00€100mg460.00€200mg620.00€Atranorin
CAS:Atranorin has antinociceptive, anti-inflammatory, can be pro-oxidant or antioxidant, and protects cells from H(2)O(2)-induced oxidative stress.Formula:C19H18O8Purity:98.76% - 99.57%Color and Shape:SolidMolecular weight:374.34CASIN
CAS:CASIN (Pirl1-related Compound 2) is a specific inhibitor of GTPase Cdc42 (IC50: 2 uM).Formula:C20H22N2OPurity:98.18% - >99.99%Color and Shape:SolidMolecular weight:306.4Ref: TM-T3971
1mg35.00€2mg50.00€5mg71.00€1mL*10mM (DMSO)71.00€10mg114.00€25mg178.00€50mg268.00€100mg413.00€500mg888.00€EHT 1864 2HCl
CAS:EHT 1864 (EHT 1864 2HCl) is a Rac family GTPase inhibitor that blocks activation by direct binding to Rac1, Rac1b, Rac2, and Rac3. Cost effective and quality assured.Formula:C25H29Cl2F3N2O4SPurity:98.39% - 99.42%Color and Shape:SolidMolecular weight:581.47Rhosin hydrochloride
CAS:Rhosin hydrochloride is a specific inhibitor of the RhoA subfamily Rho GTPases.Cost-effective and quality-assured.Formula:C20H20Cl2N6OPurity:97.33% - 98.92%Color and Shape:SolidMolecular weight:431.318Kobe0065
CAS:Kobe0065: novel small-molecule, inhibits Ras–Raf, Ki=46±13 μM, blocks H-Ras·GTP/c-Raf-1 RBD binding.Formula:C15H11ClF3N5O4SPurity:98% - >99.99%Color and Shape:SolidMolecular weight:449.79Sotorasib
CAS:Sotorasib (AMG-510) is an orally active and selective covalent inhibitor of KRAS G12C.Formula:C30H30F2N6O3Purity:98% - 99.95%Color and Shape:SolidMolecular weight:560.594Ref: TM-T8684
1mg37.00€2mg52.00€5mg79.00€1mL*10mM (DMSO)87.00€10mg126.00€25mg225.00€50mg374.00€100mg459.00€500mg1,026.00€1g1,359.00€FTI-277 hydrochloride
CAS:FTI-277 HCl: potent FTase inhibitor, IC50 500 pM, 100x more selective than GGTase I.Formula:C22H30ClN3O3S2Purity:97.57% - 97.61%Color and Shape:SolidMolecular weight:484.07Ref: TM-T2700
1mg50.00€2mg70.00€5mg90.00€1mL*10mM (DMSO)102.00€10mg158.00€25mg304.00€50mg497.00€100mg708.00€200mg964.00€(S)-AMG-510
CAS:(S)-AMG-510 is the S-type compound of AMG-510 (Sotorasib), which effectively and selectively inhibits KRASG12C.Cost-effective and quality-assured.Formula:C30H30F2N6O3Purity:99.05% - 99.76%Color and Shape:SolidMolecular weight:560.594Ref: TM-T22258
2mg34.00€5mg50.00€1mL*10mM (DMSO)73.00€10mg80.00€25mg147.00€50mg259.00€100mg404.00€500mg888.00€K-Ras(G12C) inhibitor 12
CAS:K-Ras(G12C) inhibitor 12 is an allosteric inhibitor of oncogenic K-Ras(G12C).Formula:C15H17ClIN3O3Purity:97.16%Color and Shape:SolidMolecular weight:449.67KRAS inhibitor-9
CAS:KRAS inhibitor-9 (DUN09716) hinders GTP-KRAS formation, with a Kd of 92 μM, causes G2/M arrest, and induces apoptosis in mutated NSC-LC cells.Formula:C13H9ClN2S2Purity:99.66%Color and Shape:SolidMolecular weight:292.81Ref: TM-T8756
1mg57.00€2mg81.00€5mg113.00€1mL*10mM (DMSO)136.00€10mg178.00€25mg334.00€50mg485.00€100mg622.00€ERK-IN-3
CAS:ERK-IN-3 (ASN007 free base) is a potent and orally active inhibitor of ERK.Formula:C22H25ClFN7O2Purity:99.55% - 99.76%Color and Shape:SolidMolecular weight:473.93ASP2453
CAS:ASP2453 is a potent, selective and covalent inhibitor of KRAS G12C.Formula:C40H48F3N7O4Purity:99.71%Color and Shape:SolidMolecular weight:747.85CCG-1423
CAS:CCG-1423, a selective RhoA pathway inhibitor, suppresses SRF-mediated transcription.Formula:C18H13ClF6N2O3Purity:99.80%Color and Shape:SolidMolecular weight:454.75Ref: TM-T2014
5mg35.00€1mL*10mM (DMSO)52.00€10mg54.00€25mg90.00€50mg154.00€100mg248.00€200mg385.00€500mg625.00€6H05 (TFA)
CAS:6H05 TFA (6H05 trifluoroacetate) is a selective, and allosteric oncogenic mutant K-Ras(G12C) inhibitor.Formula:C22H31ClF3N3O4S3Purity:98.83%Color and Shape:SolidMolecular weight:590.14Ref: TM-T7326
1mg65.00€2mg90.00€5mg127.00€1mL*10mM (DMSO)166.00€10mg217.00€25mg358.00€50mg538.00€100mg765.00€Z62954982
CAS:Z62954982 (ZINC08010136) is a Rac1 inhibitor that inhibits Rac1 activation and reduces proliferation, p38 phosphorylation, and IL-6 levels in pulmonary arteriesFormula:C20H21N3O5SPurity:98.28%Color and Shape:SolidMolecular weight:415.46Ref: TM-T37113
1mg35.00€5mg75.00€1mL*10mM (DMSO)87.00€10mg105.00€25mg173.00€50mg255.00€100mg371.00€200mg530.00€AZD0022
CAS:AZD0022 is a selective, reversible, and orally active KRAS G12D inhibitor, exhibits tumour marker inhibition in PDAC and NSCLC models.Formula:C34H30F4N6OPurity:98.73%Color and Shape:SoildMolecular weight:614.64Deltarasin
CAS:Deltarasin is a small molecular inhibitor of KRAS-PDEδ interaction with Kd of 38 nM for binding to purified PDEδ.Formula:C40H37N5OPurity:99.4%Color and Shape:SolidMolecular weight:603.756H05
CAS:6H05 (K-Ras inhibitor) is a selective, allosteric inhibitor of oncogenic mutant K-Ras(G12C).Formula:C20H30ClN3O2S3Purity:98%Color and Shape:SolidMolecular weight:476.12KRAS inhibitor-6
CAS:KRAS inhibitor-6 is a potent KRAS G12C inhibitor.Formula:C27H30ClF2N5O3Purity:98%Color and Shape:SolidMolecular weight:546.01Methylophiopogonanone B
CAS:1. Methylophiopogonanone B (MOPB) induces cell morphological change and Rho activation via melanocyte dendrite retraction and stress fiber formation.Formula:C19H20O5Purity:99.24% - 99.83%Color and Shape:SolidMolecular weight:328.36Ref: TM-T5S1261
1mg84.00€5mg178.00€1mL*10mM (DMSO)192.00€10mg295.00€25mg497.00€50mg708.00€100mg964.00€200mg1,288.00€Digeranyl bisphosphonate
CAS:Digeranyl bisphosphonate (DGBP) is a potent geranylgeranyl pyrophosphate (GGPP) synthase inhibitor that inhibits geranyl pyrophosphorylation of Rac1.DigeranylFormula:C21H34Na4O6P2Purity:98.5%Color and Shape:SolidMolecular weight:536.4KRAS inhibitor-7
CAS:KRAS inhibitor-7 is a potent KRAS G12C inhibitor.Formula:C26H27ClF2N6O2Purity:98%Color and Shape:SolidMolecular weight:528.98CCG-257081
CAS:CCG-257081 blocks Rho/MRTF/SRF pathway; prevents fibrosis in mice; useful in cancer and fibrosis research.Formula:C24H19ClF3N3O2Purity:99.60% - 99.94%Color and Shape:SolidMolecular weight:473.87ESI-08
CAS:ESI-08 is an effective antagonist of EPAC2 with an IC50 of 8.4 μM. ESI-08 selectively blocks cAMP-induced EPAC activation but not cAMP-mediated PKA activation.Formula:C20H23N3OSPurity:97.17%Color and Shape:SolidMolecular weight:353.48
