Ras
Ras proteins are small GTPases that act as molecular switches in the MAPK signaling pathway, controlling cell growth, differentiation, and survival. Activated Ras initiates a signaling cascade that includes Raf, MEK, and ERK, leading to various cellular responses. Mutations in Ras genes are common in cancers, making Ras an important focus of cancer research. At CymitQuimica, we offer a range of Ras modulators to support your research in cancer biology, signal transduction, and therapeutic development.
Found 155 products of "Ras"
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FTI-277 hydrochloride
CAS:<p>FTI-277 HCl: potent FTase inhibitor, IC50 500 pM, 100x more selective than GGTase I.</p>Formula:C22H30ClN3O3S2Purity:97.57% - 97.61%Color and Shape:SolidMolecular weight:484.07(S)-AMG-510
CAS:<p>(S)-AMG-510 is the S-type compound of AMG-510 (Sotorasib), which effectively and selectively inhibits KRASG12C.Cost-effective and quality-assured.</p>Formula:C30H30F2N6O3Purity:99.05% - 99.76%Color and Shape:SolidMolecular weight:560.594K-Ras(G12C) inhibitor 12
CAS:<p>K-Ras(G12C) inhibitor 12 is an allosteric inhibitor of oncogenic K-Ras(G12C).</p>Formula:C15H17ClIN3O3Purity:97.16%Color and Shape:SolidMolecular weight:449.67ERK-IN-3
CAS:<p>ERK-IN-3 (ASN007 free base) is a potent and orally active inhibitor of ERK.</p>Formula:C22H25ClFN7O2Purity:99.55% - 99.76%Color and Shape:SolidMolecular weight:473.93ASP2453
CAS:<p>ASP2453 is a potent, selective and covalent inhibitor of KRAS G12C.</p>Formula:C40H48F3N7O4Purity:99.71%Color and Shape:SolidMolecular weight:747.85CCG-1423
CAS:<p>CCG-1423, a selective RhoA pathway inhibitor, suppresses SRF-mediated transcription.</p>Formula:C18H13ClF6N2O3Purity:99.80%Color and Shape:SolidMolecular weight:454.756H05 (TFA)
CAS:<p>6H05 TFA (6H05 trifluoroacetate) is a selective, and allosteric oncogenic mutant K-Ras(G12C) inhibitor.</p>Formula:C22H31ClF3N3O4S3Purity:98.83%Color and Shape:SolidMolecular weight:590.14SCH54292
CAS:<p>SCH-54292 is a GDP exchange inhibitor.</p>Formula:C24H28N2O9SPurity:95.65%Color and Shape:SolidMolecular weight:520.55ZT-12-037-01
CAS:<p>Zt-12-037-01 is a ATP competitive STK19 inhibitor（IC50 values of 23.96 nM and 27.94 nM for STK19 (WT) and STK19 (D89N),respectively).</p>Formula:C21H31N5O2Purity:99.56%Color and Shape:SolidMolecular weight:385.5BAY-293
CAS:<p>BAY-293 is a potent, cell-active SOS1 inhibitor that disrupts the KRAS-SOS1 interaction (IC50: 21 nM).</p>Formula:C25H28N4O2SPurity:97.16%Color and Shape:SolidMolecular weight:448.58(Rac)-Antineoplaston A10
CAS:<p>Antineoplaston A10 is the first identified human antineoplaston, naturally occurring with anti-proliferative properties.</p>Formula:C13H14N2O3Purity:98.41%Color and Shape:SolidMolecular weight:246.261A-116
CAS:<p>1A-116 is a specific Rac1 inhibitor.</p>Formula:C16H16F3N3Purity:99.71%Color and Shape:SolidMolecular weight:307.31K-Ras(G12C) inhibitor 9
CAS:<p>K-Ras(G12C) inhibitor 9 is an allosteric inhibitor of oncogenic K-Ras(G12C).</p>Formula:C16H21ClIN3O4SPurity:97.33% - 97.45%Color and Shape:SolidMolecular weight:513.78RBC8
CAS:<p>RBC8 is a specific GTPases RalA/RalB inhibitor by inhibiting the binding of Ral to its effector RALBP1, no inhibition on the GTPases RhoA and Ras.</p>Formula:C25H20N4O3Purity:98.44% - 99.81%Color and Shape:SolidMolecular weight:424.45Adagrasib
CAS:<p>View and buy Adagrasib (MRTX849) from TargetMol.MRTX849 is a potent, selective and covalent KRASG12C inhibitor with potential antineoplastic activity. Cited in 2 publications.</p>Formula:C32H35ClFN7O2Purity:99.10% - 99.9%Color and Shape:SolidMolecular weight:604.12MLS000532223
CAS:<p>MLS000532223 is a selectiveRho family GTPases inhibitor(EC50 : 16 μM to 120 μM).</p>Formula:C15H9NO3Purity:98.6%Color and Shape:SolidMolecular weight:251.24ML-097
CAS:<p>ML-097 (CID-2160985) is a pan activator of Ras-related GTPases</p>Formula:C14H11BrO3Purity:99.12%Color and Shape:SolidMolecular weight:307.139ZCL278
CAS:<p>ZCL278 is a selective Cdc42 GTPase inhibitor.</p>Formula:C21H19BrClN5O4S2Purity:96.29% - 99.72%Color and Shape:SolidMolecular weight:584.89EHop-016
CAS:<p>EHop-016 is a specific Rac GTPase inhibitor with IC50 of 1.1 μM for Rac1 in MDA-MB-231 and MDA-MB-435 cells, equally effective inhibition for Rac3.</p>Formula:C25H30N6OPurity:98.99% - >99.99%Color and Shape:SolidMolecular weight:430.551-(4-methansulfinylphenyl)ethanone
CAS:<p>The compound inhibits Ras function and therefore inhibits the abnormal growth of cells.</p>Formula:C9H10O2SPurity:99.48%Color and Shape:SolidMolecular weight:182.24ARS-853
CAS:<p>ARS-853 is an inhibitor of K-RASG12C(IC50 : 2.5 μM), a mutant form of K-RAS that accumulates in the active GTP-bound state in certain cancer cells</p>Formula:C22H29ClN4O3Purity:97.43% - 98.4%Color and Shape:SolidMolecular weight:432.94Antineoplaston A10
CAS:<p>Antineoplaston A10 (NSC-648539) is a Ras inhibitor potentially for the treatment of glioma, lymphoma, astrocytoma and breast cancer.</p>Formula:C13H14N2O3Purity:99.42%Color and Shape:SolidMolecular weight:246.26Phellodendrine chloride
CAS:<p>Phellodendrine chloride combats kidney inflammation by blocking macrophage and T cell activity in glomeruli.</p>Formula:C20H24ClNO4Purity:98.85% - 99.05%Color and Shape:SolidMolecular weight:377.86NSC 23766 trihydrochloride
CAS:<p>NSC 23766 trihydrochloride (Rac1 Inhibitor) is an inhibitor of Rac GTPase targeting Rac activation by GEFs; no inhibitory for RhoA or Cdc42.</p>Formula:C24H35N7·3HClPurity:96.48% - 99.54%Color and Shape:SolidMolecular weight:530.96CID-1067700
CAS:<p>CID-1067700 is one of the first identified competitive inhibitors of nucleotide binding by Ras-related GTPases（Rab7 with a Ki of 13 nM).</p>Formula:C18H18N2O4S2Purity:99.46%Color and Shape:SolidMolecular weight:390.48MLS-573151
CAS:<p>MLS-573151 is a selective inhibitor of GTPase Cdc42(EC50 of 2 μM).</p>Formula:C21H19N3O2SPurity:98.80%Color and Shape:SolidMolecular weight:377.46CCG-222740
CAS:<p>CCG-222740 is an inhibitor of Rho/MRTF pathway</p>Formula:C23H19ClF2N2O3Purity:98.76%Color and Shape:SolidMolecular weight:444.86Salirasib
CAS:<p>Salirasib: Competitive PPMTase inhibitor, blocks Ras methylation, potential cancer treatment, Ki=2.6 μM.</p>Formula:C22H30O2SPurity:99.45%Color and Shape:SolidMolecular weight:358.54Kobe2602
CAS:<p>Kobe 2602 is an inhibitor of Ras that exhibits anticancer chemotherapeutic activities.</p>Formula:C14H9F4N5O4SPurity:98.36% - 99.39%Color and Shape:SolidMolecular weight:419.31Arglabin
CAS:<p>Arglabin ((+)-Arglabin) is a natural product isolated from Artemisia glabella, is a NLRP3 inflammasome inhibitor, has anti-atherogenic and anticancer effects.</p>Formula:C15H18O3Purity:98.97% - 99.62%Color and Shape:SolidMolecular weight:246.3BQU57
CAS:<p>BQU57 shows selective inhibition for Ral relative to Ras or Rho and inhibit xenograft tumor growth.</p>Formula:C16H13F3N4OPurity:97.45% - 98.72%Color and Shape:SolidMolecular weight:334.3Sotorasib
CAS:<p>Sotorasib (AMG-510) is an orally active and selective covalent inhibitor of KRAS G12C.</p>Formula:C30H30F2N6O3Purity:98% - 99.95%Color and Shape:SolidMolecular weight:560.594KRAS inhibitor-9
CAS:<p>KRAS inhibitor-9 (DUN09716) hinders GTP-KRAS formation, with a Kd of 92 μM, causes G2/M arrest, and induces apoptosis in mutated NSC-LC cells.</p>Formula:C13H9ClN2S2Purity:99.66%Color and Shape:SolidMolecular weight:292.81CID44216842
CAS:<p>CID44216842 is a potent Cdc42-selective inhibitor with EC50: 1.0μM (WT), 1.2μM (Q61L) in GTP assay; 0.3μM (WT), 0.5μM (Q61L) in GDP assay. Use as a probe.</p>Formula:C22H20BrN3O3SPurity:99.66%Color and Shape:SolidMolecular weight:486.38Eicosapentaenoic Acid
CAS:<p>Eicosapentaenoic Acid is an ω-3 fatty acid and an inhibitor of fatty acid synthase (FASN). High-Quality, Low-Cost!</p>Formula:C20H30O2Purity:97.03% - 99.83%Color and Shape:LiquidMolecular weight:302.45K-Ras-IN-1
CAS:<p>K-Ras-IN-1 is a K-Ras inhibitor.</p>Formula:C11H13NOSPurity:98.72%Color and Shape:SolidMolecular weight:207.29MRTX1133
CAS:<p>View and buy MRTX1133 from TargetMol.MRTX1133 is a potent, selective, and noncovalent inhibitor of KRAS G12D.</p>Formula:C33H31F3N6O2Purity:97.39% - 99.6%Color and Shape:SolidMolecular weight:600.63ML-098
CAS:<p>ML-098 (CID-7345532) is an activator of the GTP-binding protein Rab7 (EC50: 77.6 nM).</p>Formula:C19H19NO3Purity:99.06% - 99.23%Color and Shape:SolidMolecular weight:309.36Lonafarnib
CAS:<p>Lonafarnib (Sch66336) is an orally bioavailable FPTase inhibitor for H-ras, K-ras-4B, and N-ras (IC50: 1.9/5.2/2.8 nM).</p>Formula:C27H31Br2ClN4O2Purity:98% - 99.94%Color and Shape:SolidMolecular weight:638.82Oncrasin-1
CAS:<p>Oncrasin 1 is a potent inhibitor of anticancer that kills various human lung cancer cells with K-Ras mutations at low or submicromolar concentrations</p>Formula:C16H12ClNOPurity:99.75%Color and Shape:SolidMolecular weight:269.73Z62954982
CAS:<p>Z62954982 (ZINC08010136) is a Rac1 inhibitor that inhibits Rac1 activation and reduces proliferation, p38 phosphorylation, and IL-6 levels in pulmonary arteries</p>Formula:C20H21N3O5SPurity:98.28%Color and Shape:SolidMolecular weight:415.46AZD0022
CAS:<p>AZD0022 is a selective, reversible, and orally active KRAS G12D inhibitor, exhibits tumour marker inhibition in PDAC and NSCLC models.</p>Formula:C34H30F4N6OPurity:98.73%Color and Shape:SoildMolecular weight:614.64Deltarasin
CAS:<p>Deltarasin is a small molecular inhibitor of KRAS-PDEδ interaction with Kd of 38 nM for binding to purified PDEδ.</p>Formula:C40H37N5OPurity:99.4%Color and Shape:SolidMolecular weight:603.756H05
CAS:<p>6H05 (K-Ras inhibitor) is a selective, allosteric inhibitor of oncogenic mutant K-Ras(G12C).</p>Formula:C20H30ClN3O2S3Purity:98%Color and Shape:SolidMolecular weight:476.12KRas G12C inhibitor 3
CAS:<p>KRas G12C inhibitor 3 is a compound that inhibits KRas G12C.</p>Formula:C32H36ClN7O2Purity:98%Color and Shape:SolidMolecular weight:586.13KRas G12C inhibitor 4
CAS:<p>KRas G12C inhibitor 4 is a compound that inhibits KRas G12C.</p>Formula:C33H38ClN7O2Purity:98%Color and Shape:SolidMolecular weight:600.15CCG-257081
CAS:<p>CCG-257081 blocks Rho/MRTF/SRF pathway; prevents fibrosis in mice; useful in cancer and fibrosis research.</p>Formula:C24H19ClF3N3O2Purity:99.76% - 99.94%Color and Shape:SolidMolecular weight:473.87Digeranyl bisphosphonate
CAS:<p>Digeranyl bisphosphonate (DGBP) is a potent geranylgeranyl pyrophosphate (GGPP) synthase inhibitor that inhibits geranyl pyrophosphorylation of Rac1.Digeranyl</p>Formula:C21H34Na4O6P2Purity:98.5%Color and Shape:SolidMolecular weight:536.4Nexinhib20
CAS:<p>Nexinhib20 is an inhibitor of exosome synthesis and transport with anti-inflammatory activity, inhibits RAB27A and neutral sphingomyelinase 2 (nSMase2) nsMase2.</p>Formula:C15H16N4O3Purity:99.89%Color and Shape:SolidMolecular weight:300.31KRAS inhibitor-7
CAS:<p>KRAS inhibitor-7 is a potent KRAS G12C inhibitor.</p>Formula:C26H27ClF2N6O2Purity:98%Color and Shape:SolidMolecular weight:528.98
