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Ras

Ras

Ras proteins are small GTPases that act as molecular switches in the MAPK signaling pathway, controlling cell growth, differentiation, and survival. Activated Ras initiates a signaling cascade that includes Raf, MEK, and ERK, leading to various cellular responses. Mutations in Ras genes are common in cancers, making Ras an important focus of cancer research. At CymitQuimica, we offer a range of Ras modulators to support your research in cancer biology, signal transduction, and therapeutic development.

Found 155 products of "Ras"

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  • Sosimerasib
    Targetmol
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    Sosimerasib

    CAS:
    Sosimerasib is an inhibitor of the kirsten rat sarcoma viral oncogene homolog (KRAS) and exhibits antitumor activity.
    Formula:C36H39ClFN7O4
    Color and Shape:Solid
    Molecular weight:688.191

    Ref: TM-T206171

    10mg
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    50mg
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  • KRAS inhibitor-31
    Targetmol
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    KRAS inhibitor-31

    CAS:
    KRAS inhibitor-31 (compound 33), a potent agent targeting KRAS, exhibits K D (SPR) values of 0.019 nM for KRas G12D, 0.019 nM for KRas G12C, and 0.096 nM for KRas G12V, illustrating its efficacy across these variants.
    Formula:C33H30F3N5O4
    Color and Shape:Solid
    Molecular weight:617.62

    Ref: TM-T200064

    25mg
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    100mg
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  • XMU-MP-9
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    XMU-MP-9

    CAS:
    XMU-MP-9, a bifunctional compound, targets the C2 domain of Nedd4-1 and the allosteric site of K-Ras. It enhances the interaction and induces conformational changes within the Nedd4-1/K-Ras complex. Furthermore, XMU-MP-9 facilitates the ubiquitination and degradation of various K-Ras mutants and inhibits the proliferation of cells with these mutants. This compound is useful in cancer research.
    Formula:C19H13ClFN3OS
    Color and Shape:Solid
    Molecular weight:385.84

    Ref: TM-T200189

    25mg
    1,458.00€
    50mg
    1,839.00€
    100mg
    2,322.00€
  • KRas G12C inhibitor 2
    Targetmol
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    KRas G12C inhibitor 2

    CAS:
    KRas G12C inhibitor 2 is a compound that inhibits KRas G12C.
    Formula:C32H37N7O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:567.68

    Ref: TM-T11777

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • ZCL279
    Targetmol
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    ZCL279

    CAS:
    ZCL279 is a small molecule modulator (SMM) that inhibits the interaction between CDC42 and intersectin (ITSN). At lower concentrations (<10 μM), ZCL279 activates Cdc42, a cytoplasmic small GTPase in the Ras superfamily, while at higher concentrations (<10 μM) it significantly inhibits it.
    Formula:C24H18N2O7S2
    Color and Shape:Solid
    Molecular weight:510.539

    Ref: TM-T204446

    10mg
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    50mg
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