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Ras

Ras

Ras proteins are small GTPases that act as molecular switches in the MAPK signaling pathway, controlling cell growth, differentiation, and survival. Activated Ras initiates a signaling cascade that includes Raf, MEK, and ERK, leading to various cellular responses. Mutations in Ras genes are common in cancers, making Ras an important focus of cancer research. At CymitQuimica, we offer a range of Ras modulators to support your research in cancer biology, signal transduction, and therapeutic development.

Found 155 products of "Ras"

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  • AM-001

    CAS:
    <p>AM-001 is a non-competitive inhibitor of Epac1, preventing the activation of its downstream effector Rap1 in cultured cells. This compound is utilized in research related to cardiac diseases.</p>
    Formula:C24H16FN3OS2
    Color and Shape:Solid
    Molecular weight:445.53
  • KRAS inhibitor-35

    CAS:
    <p>KRAS inhibitor-35 (compound 72) is a KRAS inhibitor with an IC50 of 2 nM, utilized in tumor research.</p>
    Formula:C38H32F4N6O3S
    Color and Shape:Solid
    Molecular weight:728.76
  • KRAS inhibitor-41

    CAS:
    <p>KRAS inhibitor-41 is a KRAS inhibitor with an IC50 value of less than 0.01 μM for both KRAS G12D and KRAS G12V mutations. It effectively inhibits RAS mutant cell lines GP2D (KRAS-G12D) and SW620 (KRAS-G12V). KRAS inhibitor-41 is applicable for cancer research.</p>
    Formula:C30H37FN10OS
    Color and Shape:Solid
    Molecular weight:604.745
  • Sosimerasib

    CAS:
    <p>Sosimerasib is an inhibitor of the kirsten rat sarcoma viral oncogene homolog (KRAS) and exhibits antitumor activity.</p>
    Formula:C36H39ClFN7O4
    Color and Shape:Solid
    Molecular weight:688.191
  • KRAS G12D inhibitor 28

    CAS:
    <p>KRAS G12D inhibitor 28 (Compound 1) is an inhibitor of KRAS G12D and can be utilized in cancer research.</p>
    Formula:C35H32Cl2FN5O
    Color and Shape:Solid
    Molecular weight:628.57