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Ras

Ras

Ras proteins are small GTPases that act as molecular switches in the MAPK signaling pathway, controlling cell growth, differentiation, and survival. Activated Ras initiates a signaling cascade that includes Raf, MEK, and ERK, leading to various cellular responses. Mutations in Ras genes are common in cancers, making Ras an important focus of cancer research. At CymitQuimica, we offer a range of Ras modulators to support your research in cancer biology, signal transduction, and therapeutic development.

Found 155 products of "Ras"

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  • BQU57

    CAS:
    <p>BQU57 shows selective inhibition for Ral relative to Ras or Rho and inhibit xenograft tumor growth.</p>
    Formula:C16H13F3N4O
    Purity:97.45% - 98.72%
    Color and Shape:Solid
    Molecular weight:334.3
  • Sotorasib

    CAS:
    <p>Sotorasib (AMG-510) is an orally active and selective covalent inhibitor of KRAS G12C.</p>
    Formula:C30H30F2N6O3
    Purity:98% - 99.95%
    Color and Shape:Solid
    Molecular weight:560.594
  • KRAS inhibitor-9

    CAS:
    <p>KRAS inhibitor-9 (DUN09716) hinders GTP-KRAS formation, with a Kd of 92 μM, causes G2/M arrest, and induces apoptosis in mutated NSC-LC cells.</p>
    Formula:C13H9ClN2S2
    Purity:99.66%
    Color and Shape:Solid
    Molecular weight:292.81
  • CID44216842

    CAS:
    <p>CID44216842 is a potent Cdc42-selective inhibitor with EC50: 1.0μM (WT), 1.2μM (Q61L) in GTP assay; 0.3μM (WT), 0.5μM (Q61L) in GDP assay. Use as a probe.</p>
    Formula:C22H20BrN3O3S
    Purity:99.66%
    Color and Shape:Solid
    Molecular weight:486.38
  • Eicosapentaenoic Acid

    CAS:
    <p>Eicosapentaenoic Acid is an ω-3 fatty acid and an inhibitor of fatty acid synthase (FASN). High-Quality, Low-Cost!</p>
    Formula:C20H30O2
    Purity:97.03% - 99.83%
    Color and Shape:Liquid
    Molecular weight:302.45
  • K-Ras-IN-1

    CAS:
    <p>K-Ras-IN-1 is a K-Ras inhibitor.</p>
    Formula:C11H13NOS
    Purity:98.72%
    Color and Shape:Solid
    Molecular weight:207.29
  • MRTX1133

    CAS:
    <p>View and buy MRTX1133 from TargetMol.MRTX1133 is a potent, selective, and noncovalent inhibitor of KRAS G12D.</p>
    Formula:C33H31F3N6O2
    Purity:97.39% - 99.6%
    Color and Shape:Solid
    Molecular weight:600.63
  • ML-098

    CAS:
    <p>ML-098 (CID-7345532) is an activator of the GTP-binding protein Rab7 (EC50: 77.6 nM).</p>
    Formula:C19H19NO3
    Purity:99.06% - 99.23%
    Color and Shape:Solid
    Molecular weight:309.36
  • Lonafarnib

    CAS:
    <p>Lonafarnib (Sch66336) is an orally bioavailable FPTase inhibitor for H-ras, K-ras-4B, and N-ras (IC50: 1.9/5.2/2.8 nM).</p>
    Formula:C27H31Br2ClN4O2
    Purity:98% - 99.94%
    Color and Shape:Solid
    Molecular weight:638.82
  • Oncrasin-1

    CAS:
    <p>Oncrasin 1 is a potent inhibitor of anticancer that kills various human lung cancer cells with K-Ras mutations at low or submicromolar concentrations</p>
    Formula:C16H12ClNO
    Purity:99.75%
    Color and Shape:Solid
    Molecular weight:269.73
  • Z62954982

    CAS:
    <p>Z62954982 (ZINC08010136) is a Rac1 inhibitor that inhibits Rac1 activation and reduces proliferation, p38 phosphorylation, and IL-6 levels in pulmonary arteries</p>
    Formula:C20H21N3O5S
    Purity:98.28%
    Color and Shape:Solid
    Molecular weight:415.46
  • AZD0022

    CAS:
    <p>AZD0022 is a selective, reversible, and orally active KRAS G12D inhibitor, exhibits tumour marker inhibition in PDAC and NSCLC models.</p>
    Formula:C34H30F4N6O
    Purity:98.73%
    Color and Shape:Soild
    Molecular weight:614.64
  • Deltarasin

    CAS:
    <p>Deltarasin is a small molecular inhibitor of KRAS-PDEδ interaction with Kd of 38 nM for binding to purified PDEδ.</p>
    Formula:C40H37N5O
    Purity:99.4%
    Color and Shape:Solid
    Molecular weight:603.75
  • 6H05

    CAS:
    <p>6H05 (K-Ras inhibitor) is a selective, allosteric inhibitor of oncogenic mutant K-Ras(G12C).</p>
    Formula:C20H30ClN3O2S3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:476.12
  • KRas G12C inhibitor 3

    CAS:
    <p>KRas G12C inhibitor 3 is a compound that inhibits KRas G12C.</p>
    Formula:C32H36ClN7O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:586.13
  • KRas G12C inhibitor 4

    CAS:
    <p>KRas G12C inhibitor 4 is a compound that inhibits KRas G12C.</p>
    Formula:C33H38ClN7O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:600.15
  • CCG-257081

    CAS:
    <p>CCG-257081 blocks Rho/MRTF/SRF pathway; prevents fibrosis in mice; useful in cancer and fibrosis research.</p>
    Formula:C24H19ClF3N3O2
    Purity:99.76% - 99.94%
    Color and Shape:Solid
    Molecular weight:473.87
  • Digeranyl bisphosphonate

    CAS:
    <p>Digeranyl bisphosphonate (DGBP) is a potent geranylgeranyl pyrophosphate (GGPP) synthase inhibitor that inhibits geranyl pyrophosphorylation of Rac1.Digeranyl</p>
    Formula:C21H34Na4O6P2
    Purity:98.5%
    Color and Shape:Solid
    Molecular weight:536.4
  • Nexinhib20

    CAS:
    <p>Nexinhib20 is an inhibitor of exosome synthesis and transport with anti-inflammatory activity, inhibits RAB27A and neutral sphingomyelinase 2 (nSMase2) nsMase2.</p>
    Formula:C15H16N4O3
    Purity:99.89%
    Color and Shape:Solid
    Molecular weight:300.31
  • KRAS inhibitor-7

    CAS:
    <p>KRAS inhibitor-7 is a potent KRAS G12C inhibitor.</p>
    Formula:C26H27ClF2N6O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:528.98