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Ras

Ras

Ras proteins are small GTPases that act as molecular switches in the MAPK signaling pathway, controlling cell growth, differentiation, and survival. Activated Ras initiates a signaling cascade that includes Raf, MEK, and ERK, leading to various cellular responses. Mutations in Ras genes are common in cancers, making Ras an important focus of cancer research. At CymitQuimica, we offer a range of Ras modulators to support your research in cancer biology, signal transduction, and therapeutic development.

Found 155 products of "Ras"

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  • ESI-08
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    ESI-08

    CAS:
    <p>ESI-08 is an effective antagonist of EPAC2 with an IC50 of 8.4 μM. ESI-08 selectively blocks cAMP-induced EPAC activation but not cAMP-mediated PKA activation.</p>
    Formula:C20H23N3OS
    Purity:97.17%
    Color and Shape:Solid
    Molecular weight:353.48

    Ref: TM-T11234

  • KRAS inhibitor-6
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    KRAS inhibitor-6

    CAS:
    <p>KRAS inhibitor-6 is a potent KRAS G12C inhibitor.</p>
    Formula:C27H30ClF2N5O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:546.01

    Ref: TM-T11773

  • Methylophiopogonanone B
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    Methylophiopogonanone B

    CAS:
    <p>1. Methylophiopogonanone B (MOPB) induces cell morphological change and Rho activation via melanocyte dendrite retraction and stress fiber formation.</p>
    Formula:C19H20O5
    Purity:99.24% - 99.83%
    Color and Shape:Solid
    Molecular weight:328.36

    Ref: TM-T5S1261

  • MCP110
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    MCP110

    CAS:
    <p>MCP110 is an inhibitor of the interaction of Ras with Raf-1 and can be used in studies about the treatment of human tumors.</p>
    Formula:C33H36N2O3
    Purity:97.23%
    Color and Shape:Oil
    Molecular weight:508.65

    Ref: TM-T24437

  • BI-2852
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    BI-2852

    CAS:
    <p>BI-2852: nanomolar affinity KRAS switch I/II pocket inhibitor; blocks signaling, halts KRAS mutant cell growth.</p>
    Formula:C31H28N6O2
    Purity:98.98%
    Color and Shape:Solid
    Molecular weight:516.59

    Ref: TM-T10533

  • PROTAC KRAS G12C degrader-3
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    PROTAC KRAS G12C degrader-3

    CAS:
    <p>PROTAC KRAS G12C Degrader-3 (Comp 283) serves as a potent degrader of KRAS G12C, utilized in cancer research [1].</p>
    Formula:C63H75ClN14O6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1159.81

    Ref: TM-T79148

  • KRAS G12C inhibitor 58
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    KRAS G12C inhibitor 58

    CAS:
    <p>KRAS G12C inhibitor 58 is utilized in cancer research as an inhibitor of the KRAS G12C mutation [1].</p>
    Formula:C51H64ClF4N9O8S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1074.62

    Ref: TM-T79057

  • KRAS G12C inhibitor 5
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    KRAS G12C inhibitor 5

    CAS:
    <p>KRAS G12C inhibitor 5 is a KRas G12C inhibitor.</p>
    Formula:C32H37N7O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:551.68

    Ref: TM-T11780

  • KRAS G12D modulator-1
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    KRAS G12D modulator-1

    CAS:
    <p>KRAS G12D modulator-1 (compound 6), a potent modulator of KRAS G12D, exhibits IC50 values ranging from 1-10 μM against NEA-G12D, PPI-G12D, and p ERK-AGS, and is</p>
    Formula:C30H36FN5O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:549.64

    Ref: TM-T79072

  • Rac1-IN-3
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    Rac1-IN-3

    CAS:
    <p>Rac1-IN-3 (Compound 2) is a Rac1 inhibitor exhibiting an inhibitory concentration 50 (IC50) of 46.1 μM [1].</p>
    Formula:C21H23N7O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:405.45

    Ref: TM-T79869

  • TH-Z827
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    TH-Z827

    CAS:
    <p>TH-Z827 is a mutant-selective inhibitor targeting KRAS(G12D) with an IC50 of 2.4 μM, demonstrating specificity by not binding to KRAS(WT) or KRAS(G12C).</p>
    Formula:C30H38N6O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:498.66

    Ref: TM-T79092

  • KRAS G12C inhibitor 32
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    KRAS G12C inhibitor 32

    CAS:
    <p>KRAS G12C Inhibitor 32, an eight-membered heterocyclic compound with nitrogen, acts as a potent inhibitor of KRAS G12C [1].</p>
    Formula:C29H30Cl3FN6O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:635.94

    Ref: TM-T72335

  • SOS1/KRAS-IN-1
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    SOS1/KRAS-IN-1

    CAS:
    <p>SOS1/KRAS-IN-1 (Compound 2) serves as an inhibitor of SOS1/KRAS, with potential application in the study of diseases mediated by SOS1/KRAS [1].</p>
    Formula:C24H26F3N5O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:457.49

    Ref: TM-T79162

  • pan-KRAS-IN-2
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    pan-KRAS-IN-2

    CAS:
    <p>Pan-KRAS-IN-2 (compound 6) is a broad-spectrum KRAS inhibitor exhibiting potent activity with IC50 values of ≤10 nM against KRAS wild type and its mutants (G12D</p>
    Formula:C34H34F2N4O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:584.66

    Ref: TM-T79800

  • pan-KRAS-IN-3
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    pan-KRAS-IN-3

    CAS:
    <p>Pan-KRAS-IN-3 (Example 84) is a pan-KRAS inhibitor suitable for cancer research [1].</p>
    Formula:C33H32F3N5O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:587.63

    Ref: TM-T79814

  • KRas G12C inhibitor 1
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    KRas G12C inhibitor 1

    CAS:
    <p>KRas G12C inhibitor 1 is a compound that inhibits KRas G12C.</p>
    Formula:C31H38N6O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:542.67

    Ref: TM-T11776

  • XRP44X
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    XRP44X

    CAS:
    <p>XRP44X (XRP 44X) is a potent inhibitor of Ras-Net (Elk-3) pathway.</p>
    Formula:C21H21ClN4O
    Purity:99.67%
    Color and Shape:Solid
    Molecular weight:380.87

    Ref: TM-T20759

  • KRAS G12C inhibitor 59
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    KRAS G12C inhibitor 59

    CAS:
    <p>KRAS G12C Inhibitor 59 is a compound with anticancer properties.</p>
    Formula:C32H39F6N7O5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:715.69

    Ref: TM-T79150

  • RBC10
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    RBC10

    CAS:
    <p>RBC10 inhibits the binding of Ral to its effector RALBP1, as well as inhibiting Ral-mediated cell spreading of murine embryonic fibroblasts and anchorage-</p>
    Formula:C24H25ClN2O2
    Purity:99.71%
    Color and Shape:Solid
    Molecular weight:408.92

    Ref: TM-T24706

  • KRAS G12C inhibitor 14
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    KRAS G12C inhibitor 14

    CAS:
    <p>KRAS G12C inhibitor 14 is a potent KRAS G12C inhibitor with an IC 50 of 18 nM [1].</p>
    Formula:C24H19ClF2N4O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:484.88

    Ref: TM-T11768