Ras
Ras proteins are small GTPases that act as molecular switches in the MAPK signaling pathway, controlling cell growth, differentiation, and survival. Activated Ras initiates a signaling cascade that includes Raf, MEK, and ERK, leading to various cellular responses. Mutations in Ras genes are common in cancers, making Ras an important focus of cancer research. At CymitQuimica, we offer a range of Ras modulators to support your research in cancer biology, signal transduction, and therapeutic development.
Found 155 products of "Ras"
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ARS-1323
CAS:ARS-1323 is the racemate of ARS-1620 and a mutant K-ras G12C inhibitor.Formula:C21H17ClF2N4O2Purity:99.53%Color and Shape:SolidMolecular weight:430.84Ref: TM-T10375
2mg38.00€5mg56.00€1mL*10mM (DMSO)63.00€10mg94.00€25mg129.00€50mg168.00€100mg235.00€200mg350.00€KRAS G12C inhibitor 13
CAS:KRAS G12C inhibitor 13 is a KRAS G12C inhibitor .Formula:C40H46F3N7O4Purity:98%Color and Shape:SolidMolecular weight:745.83KRAS G12C inhibitor 32
CAS:KRAS G12C Inhibitor 32, an eight-membered heterocyclic compound with nitrogen, acts as a potent inhibitor of KRAS G12C [1].Formula:C29H30Cl3FN6O3Purity:98%Color and Shape:SolidMolecular weight:635.94SOS1/KRAS-IN-1
CAS:SOS1/KRAS-IN-1 (Compound 2) serves as an inhibitor of SOS1/KRAS, with potential application in the study of diseases mediated by SOS1/KRAS [1].Formula:C24H26F3N5OPurity:98%Color and Shape:SolidMolecular weight:457.49KRas G12C inhibitor 1
CAS:KRas G12C inhibitor 1 is a compound that inhibits KRas G12C.Formula:C31H38N6O3Purity:98%Color and Shape:SolidMolecular weight:542.67BDP9066
CAS:BDP9066 is a potent and selective MRCK inhibitor, inhibits MRCKβ and MRCKα/β, and can be used for the prevention and treatment of skin cancer.Formula:C20H24N6Purity:98.18%Color and Shape:SolidMolecular weight:348.44Ref: TM-T14521
1mg54.00€5mg114.00€1mL*10mM (DMSO)126.00€10mg178.00€25mg409.00€50mg708.00€100mg1,224.00€500mg2,448.00€Pan-RAS-IN-1
CAS:Pan-RAS-IN-1 is an inhibitor of pan-Ras. It disrupts the interaction of Ras proteins and their effectors.Formula:C36H41Cl2F3N6O2Purity:99.77%Color and Shape:SolidMolecular weight:717.65Ref: TM-T16432
1mg75.00€2mg92.00€5mg137.00€10mg205.00€1mL*10mM (DMSO)210.00€25mg416.00€50mg625.00€100mg888.00€500mg1,783.00€Rho GTPase inhibitor 1
CAS:Rho GTPase inhibitor 1 (compound 7) is a potent inhibitor of Rho GTPase. It exhibits high affinity for Cdc42, Rac1, and RhoA, with dissociation constants (KDs) of 151 μM, 352 μM, and 232 μM, respectively. Additionally, Rho GTPase inhibitor 1 reduces cell migration in glioblastoma cell lines.Formula:C18H16N2OColor and Shape:SolidMolecular weight:276.33ADT-1004
CAS:ADT-1004 is an inhibitor of RAS. It can be used for research involving Ras-mediated diseases.Formula:C33H36FN3O6Color and Shape:SoildMolecular weight:589.65(+)-Perillyl alcohol
CAS:(+)-Perillyl alcohol (0.25-1 mM) inhibits cell growth in SW480 cells. At a concentration of 1 mM and a duration of 24 hours, (+)-Perillyl alcohol increases the number of cells in the G0/G1 phase and reduces the number in the S phase in SW480 cells.Formula:C10H16OColor and Shape:SolidMolecular weight:152.23PAT-IN-1
CAS:PAT-IN-1, a protein acyl transferases (PAT) inhibitor, competitively inhibits Erf2 autopalmitoylation (WO2017011518A1; compound 13) [1].Formula:C45H68N4OColor and Shape:SolidMolecular weight:681.05KRAS G12C inhibitor 15
CAS:KRAS G12C inhibitor 15 is a potent KRAS G12C inhibitor .Formula:C25H21ClF2N4O3Purity:98%Color and Shape:SolidMolecular weight:498.91J-104871
CAS:J-104871 (UNII-6137X5QNJF) is an FTase inhibitor that inhibits tumor growth in nude mice transplanted with activated H-ras-transformed NIH3T3 cells.Formula:C38H32N2O12Purity:99.03%Color and Shape:SolidMolecular weight:708.67KRAS inhibitor-35
CAS:KRAS inhibitor-35 (compound 72) is a KRAS inhibitor with an IC50 of 2 nM, utilized in tumor research.Formula:C38H32F4N6O3SColor and Shape:SolidMolecular weight:728.76SOF-436
CAS:SOF-436 is a KRAS inhibitor that can suppress SOS1-mediated KRAS nucleotide exchange (IC50 = 60 μM) and inhibit the interaction between KRAS and the effector protein RAF. SOF-436 is applicable to cancer research.Formula:C15H13F2NO4S2Color and Shape:SolidMolecular weight:373.395KRAS inhibitor-34
CAS:KRAS inhibitor-34 (compound 27) is a KRAS inhibitor with an IC50 of 6.4 nM and is utilized in oncological research.Formula:C43H41F3N6O3Color and Shape:SolidMolecular weight:746.82pan-KRAS degrader 1
CAS:Pan-KRAS degrader 1 (Compound 1) is a broad-spectrum KRAS degrader, exhibiting an inhibitory constant Ki value of 25 nM against KRASG12V as determined by surface plasmon resonance (SPR). Additionally, this compound demonstrates antitumor activity.Formula:C22H26N8OSColor and Shape:SolidMolecular weight:450.56KRAS inhibitor-37
CAS:KRAS inhibitor-37 (compound 2) is a potent inhibitor of KRAS, exhibiting low dissociation constants (KD) with various KRAS mutations: wild type (0.004 nM), G12D (0.041 nM), G12C (0.019 nM), and G12V (0.144 nM). This compound effectively inhibits cell proliferation, demonstrating half-maximal inhibitory concentrations (IC50) ranging from <2 nM to 14 nM in H358, SW620, and PANC08.13 cell lines. KRAS inhibitor-37 holds potential for cancer research applications.Formula:C32H33ClFN7O3Color and Shape:SolidMolecular weight:618.10BMS-214662
CAS:BMS-214662 is a selective farnesyl transferase inhibitor with anti-tumor activity, used in research on pancreatic cancer, head and neck cancer, and lung cancer.Formula:C25H23N5O2S2Purity:99.58% - 99.58%Color and Shape:SolidMolecular weight:489.61AM-001
CAS:AM-001 is a non-competitive inhibitor of Epac1, preventing the activation of its downstream effector Rap1 in cultured cells. This compound is utilized in research related to cardiac diseases.Formula:C24H16FN3OS2Color and Shape:SolidMolecular weight:445.53
