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Ras

Ras

Ras proteins are small GTPases that act as molecular switches in the MAPK signaling pathway, controlling cell growth, differentiation, and survival. Activated Ras initiates a signaling cascade that includes Raf, MEK, and ERK, leading to various cellular responses. Mutations in Ras genes are common in cancers, making Ras an important focus of cancer research. At CymitQuimica, we offer a range of Ras modulators to support your research in cancer biology, signal transduction, and therapeutic development.

Found 155 products of "Ras"

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  • KRAS G12C inhibitor 17
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    KRAS G12C inhibitor 17

    CAS:
    <p>KRAS G12C inhibitor 17 is a potent KRAS G12C inhibitor.</p>
    Formula:C24H20ClF2N3O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:471.88

    Ref: TM-T11771

  • CCG-232964
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    CCG-232964

    CAS:
    <p>CCG-232964 is an orally active Rho/MRTF/SRF inhibitor that suppresses LPA-induced CTGF gene expression [1].</p>
    Formula:C15H15ClN2O3S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:338.81

    Ref: TM-T82766

  • ML-099
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    ML-099

    CAS:
    <p>ML-099 is a pan Ras-related GTPases activator that activates Rac1, Ras, GTP-binding protein (Rab7), Rab2A and cell division cycle 42.</p>
    Formula:C14H13NO2S
    Purity:99.73%
    Color and Shape:Solid
    Molecular weight:259.32

    Ref: TM-T22991

  • KRAS G12C inhibitor 13
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    KRAS G12C inhibitor 13

    CAS:
    <p>KRAS G12C inhibitor 13 is a KRAS G12C inhibitor .</p>
    Formula:C40H46F3N7O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:745.83

    Ref: TM-T11767

  • ARS-1323
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    ARS-1323

    CAS:
    <p>ARS-1323 is the racemate of ARS-1620 and a mutant K-ras G12C inhibitor.</p>
    Formula:C21H17ClF2N4O2
    Purity:99.53%
    Color and Shape:Solid
    Molecular weight:430.84

    Ref: TM-T10375

  • pan-KRAS-IN-4
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    pan-KRAS-IN-4

    CAS:
    <p>Pan-KRAS-IN-4 (compound 5) is a potent KRAS inhibitor, demonstrating IC50 values of 0.37 nM for Kras G12C and 0.19 nM for Kras G12V [1].</p>
    Formula:C36H34F2N6O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:636.69

    Ref: TM-T79799

  • BDP9066
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    BDP9066

    CAS:
    <p>BDP9066 is a potent and selective MRCK inhibitor, inhibits MRCKβ and MRCKα/β, and can be used for the prevention and treatment of skin cancer.</p>
    Formula:C20H24N6
    Purity:98.18%
    Color and Shape:Solid
    Molecular weight:348.44

    Ref: TM-T14521

  • Pan-RAS-IN-1
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    Pan-RAS-IN-1

    CAS:
    <p>Pan-RAS-IN-1 is an inhibitor of pan-Ras. It disrupts the interaction of Ras proteins and their effectors.</p>
    Formula:C36H41Cl2F3N6O2
    Purity:99.77%
    Color and Shape:Solid
    Molecular weight:717.65

    Ref: TM-T16432

  • Rho GTPase inhibitor 1
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    Rho GTPase inhibitor 1

    CAS:
    <p>Rho GTPase inhibitor 1 (compound 7) is a potent inhibitor of Rho GTPase. It exhibits high affinity for Cdc42, Rac1, and RhoA, with dissociation constants (KDs) of 151 μM, 352 μM, and 232 μM, respectively. Additionally, Rho GTPase inhibitor 1 reduces cell migration in glioblastoma cell lines.</p>
    Formula:C18H16N2O
    Color and Shape:Solid
    Molecular weight:276.33

    Ref: TM-T207196

  • SOS2 ligand 1
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    SOS2 ligand 1

    CAS:
    <p>SOS2 ligand 1 (compound 2) is a selective ligand for son of sevenless 2 (SOS2), exhibiting a KD value of 4.6 µM.</p>
    Formula:C19H21N5O
    Color and Shape:Solid
    Molecular weight:335.403

    Ref: TM-T204872

  • (+)-Perillyl alcohol
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    (+)-Perillyl alcohol

    CAS:
    <p>(+)-Perillyl alcohol (0.25-1 mM) inhibits cell growth in SW480 cells. At a concentration of 1 mM and a duration of 24 hours, (+)-Perillyl alcohol increases the number of cells in the G0/G1 phase and reduces the number in the S phase in SW480 cells.</p>
    Formula:C10H16O
    Color and Shape:Solid
    Molecular weight:152.23

    Ref: TM-T88792

  • PAT-IN-1
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    PAT-IN-1

    CAS:
    <p>PAT-IN-1, a protein acyl transferases (PAT) inhibitor, competitively inhibits Erf2 autopalmitoylation (WO2017011518A1; compound 13) [1].</p>
    Formula:C45H68N4O
    Color and Shape:Solid
    Molecular weight:681.05

    Ref: TM-T87110

  • KRAS G12C inhibitor 15
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    KRAS G12C inhibitor 15

    CAS:
    <p>KRAS G12C inhibitor 15 is a potent KRAS G12C inhibitor .</p>
    Formula:C25H21ClF2N4O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:498.91

    Ref: TM-T11769

  • KRAS inhibitor-8
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    KRAS inhibitor-8

    CAS:
    <p>KRAS inhibitor-8 is a potent KRAS G12C inhibitor.</p>
    Formula:C26H24ClF4N5O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:565.95

    Ref: TM-T11775

  • KRAS G12D inhibitor 26
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    KRAS G12D inhibitor 26

    CAS:
    <p>KRAS G12D inhibitor 26 (Compound 64B) is an inhibitor of KRAS G12D with an IC50 ≤ 100 nM.</p>
    Formula:C35H44ClFN8O2
    Purity:99.93%
    Color and Shape:Solid
    Molecular weight:663.23

    Ref: TM-T205666

  • INCB159020
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    INCB159020

    CAS:
    <p>INCB159020 is an orally active inhibitor of KRAS G12D, exhibiting a KRAS G12D SPR value of 2.2 nM. It demonstrates anti-tumor activity.</p>
    Formula:C37H35ClFN7O2
    Color and Shape:Solid
    Molecular weight:664.171

    Ref: TM-T204240

  • pan-KRAS-IN-17
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    pan-KRAS-IN-17

    CAS:
    <p>pan-KRAS-IN-17 (Example 34) is an inhibitor that targets multiple forms of the KRAS protein.</p>
    Formula:C34H33F3N5O8P
    Color and Shape:Solid
    Molecular weight:727.623

    Ref: TM-T205570

  • KRAS inhibitor-34
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    KRAS inhibitor-34

    CAS:
    <p>KRAS inhibitor-34 (compound 27) is a KRAS inhibitor with an IC50 of 6.4 nM and is utilized in oncological research.</p>
    Formula:C43H41F3N6O3
    Color and Shape:Solid
    Molecular weight:746.82

    Ref: TM-T200670

  • SOF-436
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    SOF-436

    CAS:
    <p>SOF-436 is a KRAS inhibitor that can suppress SOS1-mediated KRAS nucleotide exchange (IC50 = 60 μM) and inhibit the interaction between KRAS and the effector protein RAF. SOF-436 is applicable to cancer research.</p>
    Formula:C15H13F2NO4S2
    Color and Shape:Solid
    Molecular weight:373.395

    Ref: TM-T206673

  • J-104871
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    J-104871

    CAS:
    <p>J-104871 (UNII-6137X5QNJF) is an FTase inhibitor that inhibits tumor growth in nude mice transplanted with activated H-ras-transformed NIH3T3 cells.</p>
    Formula:C38H32N2O12
    Purity:98%
    Color and Shape:Solid
    Molecular weight:708.67

    Ref: TM-T24188