CymitQuimica logo
ERK

ERK

ERK is a key protein in the MAPK (Mitogen-Activated Protein Kinase) signaling pathway, which is involved in transmitting signals from cell surface receptors to the DNA in the cell nucleus. ERK plays a crucial role in the regulation of various cellular processes, including proliferation, differentiation, and survival. Dysregulation of ERK signaling is associated with the development of cancer and other diseases, making it an important target for therapeutic intervention. At CymitQuimica, we offer a selection of high-quality ERK inhibitors and modulators to support your research in cell signaling, oncology, and therapeutic development.

Found 204 products of "ERK"

Sort by

Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
products per page.
  • Ravoxertinib hydrochloride

    CAS:
    <p>Ravoxertinib hydrochloride is an orally bioavailable and selective inhibitor for ERK kinase activity (IC50: 6.1 nM and 3.1 nM for ERK1 and ERK2, respectively).</p>
    Formula:C21H19Cl2FN6O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:477.32

    Ref: TM-T15377

    1mg
    Discontinued
    Discontinued product
  • Omtriptolide

    CAS:
    Omtriptolide, triptolide purified from the Chinese herb, is a water-soluble derivative prodrug.
    Formula:C24H28O9
    Purity:98%
    Color and Shape:Solid
    Molecular weight:460.479

    Ref: TM-T16390

    1mg
    Discontinued
    Discontinued product
  • Pamoic acid

    CAS:
    <p>Pamoic acid is the orphan G protein-coupled receptor GPR35 agonist. Pamoic acid activates ERK and beta-arrestin2 and causes antinociceptive activity.</p>
    Formula:C23H16O6
    Purity:99.99%
    Color and Shape:Fine Yellow Powder
    Molecular weight:388.37

    Ref: TM-T8353

    1g
    Discontinued
    1ml*10 (DMSO)
    Discontinued
    Discontinued product
  • WQ-C-401

    CAS:
    <p>WQ-C-401 is an orally active inhibitor of the platelet-derived growth factor receptor (PDGFR). It inhibits cell proliferation by blocking PDGFR auto-phosphorylation in a concentration-dependent manner, with EC50 values of 3.5 nM for PDGFRαY849 and 5.8 nM for PDGFRβY1021. Additionally, WQ-C-401 suppresses the proliferation and migration of PASMCs by inhibiting PDGF-BB-induced phosphorylation of ERK1/2, reduces collagen I synthesis, and increases α-SMA expression, thereby preventing pulmonary vascular remodeling. This compound shows promise for research in the field of pulmonary arterial hypertension.</p>
    Formula:C24H26N4O3
    Color and Shape:Solid
    Molecular weight:418.49

    Ref: TM-T200766

    10mg
    Discontinued
    25mg
    Discontinued
    50mg
    Discontinued
    100mg
    Discontinued
    Discontinued product