ERK
ERK is a key protein in the MAPK (Mitogen-Activated Protein Kinase) signaling pathway, which is involved in transmitting signals from cell surface receptors to the DNA in the cell nucleus. ERK plays a crucial role in the regulation of various cellular processes, including proliferation, differentiation, and survival. Dysregulation of ERK signaling is associated with the development of cancer and other diseases, making it an important target for therapeutic intervention. At CymitQuimica, we offer a selection of high-quality ERK inhibitors and modulators to support your research in cell signaling, oncology, and therapeutic development.
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Ulixertinib
CAS:869886-67-9
Ulixertinib (VRT752271) (BVD-523, VRT752271) is an effective and reversible ERK1/ERK2 inhibitor. The IC50 of Ulixertinib …
Formula:
C21H22Cl2N4O2
Purity:
99.41% - 99.95%
Color and Shape:
Solid
Molecular weight:
433.33
Ref: TM-T7005
| 2mg | 40.00 € | ||
| 5mg | 59.00 € | ||
| 10mg | 96.00 € | ||
| 25mg | 138.00 € | ||
| 50mg | 183.00 € | ||
| 100mg | 347.00 € | ||
| 200mg | 503.00 € | ||
| 500mg | 796.00 € | ||
| 1mL*10mM (DMSO) | 67.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
MRTX1133
CAS:2621928-55-8
View and buy MRTX1133 from TargetMol.MRTX1133 is a potent, selective, and noncovalent inhibitor of KRAS …
Formula:
C33H31F3N6O2
Purity:
97.39% - 99.10%
Color and Shape:
Solid
Molecular weight:
600.63
Ref: TM-T9303
| 1mg | 185.00 € | ||
| 5mg | 397.00 € | ||
| 10mg | 607.00 € | ||
| 25mg | 932.00 € | ||
| 50mg | 1,318.00 € | ||
| 100mg | 1,794.00 € | ||
| 1mL*10mM (DMSO) | 523.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
ERK-IN-3
CAS:2055597-12-9
ERK-IN-3 (ASN007 free base) is a potent and orally active inhibitor of ERK.
Formula:
C22H25ClFN7O2
Purity:
99.55% - 99.76%
Color and Shape:
Solid
Molecular weight:
473.93
Ref: TM-T9141
| 1mg | 60.00 € | ||
| 5mg | 122.00 € | ||
| 10mg | 172.00 € | ||
| 25mg | 280.00 € | ||
| 50mg | 457.00 € | ||
| 1mL*10mM (DMSO) | 124.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Sophocarpine
CAS:6483-15-4
Sophocarpine, a major ingredient of Sophora alopecuroides, has a wide range of pharmacological effects.
Formula:
C15H22N2O
Purity:
98.67%
Color and Shape:
Solid
Molecular weight:
246.35
Ref: TM-T6677
| 5mg | 49.00 € | ||
| 10mg | 78.00 € | ||
| 25mg | 141.00 € | ||
| 50mg | 200.00 € | ||
| 100mg | 300.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
VX-11e
CAS:896720-20-0
VX-11e (TCS ERK 11e) is a potent, selective, and orally bioavailable ERK(Extracellular Signal-Regulated Kinase) inhibitor; …
Formula:
C24H20Cl2FN5O2
Purity:
98.92% - ≥98%
Color and Shape:
Solid
Molecular weight:
500.35
Ref: TM-T3166
| 2mg | 54.00 € | ||
| 5mg | 87.00 € | ||
| 10mg | 120.00 € | ||
| 25mg | 222.00 € | ||
| 50mg | 351.00 € | ||
| 100mg | 544.00 € | ||
| 1mL*10mM (DMSO) | 95.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Methylnissolin
CAS:73340-41-7
Methylnissolin (3-Hydroxy-9,10-dimethoxyptercarpan) is derived from Astragalus and has antibacterial and anti-cancer effects.
Formula:
C17H16O5
Purity:
99.68% - 99.98%
Color and Shape:
Solid
Molecular weight:
300.31
Ref: TM-TN2354
| 1mg | 87.00 € | ||
| 5mg | 198.00 € | ||
| 10mg | 305.00 € | ||
| 25mg | 513.00 € | ||
| 50mg | 732.00 € | ||
| 1mL*10mM (DMSO) | 185.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
EF24
CAS:342808-40-6
EF24 treatment boosts caspase 3/9 activity, hinders MEK1/ERK phosphorylation, and exhibits strong anti-tumor effects in …
Formula:
C19H15F2NO
Purity:
98.47%
Color and Shape:
Solid
Molecular weight:
311.33
Ref: TM-T27242
| 1g | 1,491.00 € | ||
| 1mg | 40.00 € | ||
| 5mg | 84.00 € | ||
| 10mg | 131.00 € | ||
| 25mg | 232.00 € | ||
| 50mg | 349.00 € | ||
| 100mg | 527.00 € | ||
| 500mg | 1,116.00 € | ||
| 1mL*10mM (DMSO) | 92.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Tauroursodeoxycholate dihydrate
CAS:117609-50-4
Tauroursodeoxycholate dihydrate is an endoplasmic reticulum stress inhibitor.
Formula:
C26H49NO8S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
535.73
Ref: TM-T16998
| 25mg | To inquire | ||
| 50mg | To inquire | ||
| 100mg | To inquire |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Deltonin
CAS:55659-75-1
Deltonin inhibits ERK1/2 & AKT; toxic to HepG2 (IC50: 7.66μM), C26 (IC50: 1.22μM), MDA-MB-231 cells …
Formula:
C45H72O17
Purity:
99.79%
Color and Shape:
Solid
Molecular weight:
885.04
Ref: TM-T3844
| 1mg | 121.00 € | ||
| 5mg | 292.00 € | ||
| 50mg | 932.00 € | ||
| 1mL*10mM (DMSO) | 450.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
trans-Zeatin
CAS:1637-39-4
trans-Zeatin ((E)-Zeatin) is the member of the plant growth hormone family known as cytokinins, which …
Formula:
C10H13N5O
Purity:
97.13% - 98%
Color and Shape:
White To Light Yellow Crystal Powder
Molecular weight:
219.24
Ref: TM-TMS2181
| 25mg | 54.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Corynoxeine
CAS:630-94-4
Corynoxeine inhibits ERK1/2, curbs VSMC growth induced by PDGF-BB, and may prevent vascular diseases and …
Formula:
C22H26N2O4
Purity:
98.61% - 99.73%
Color and Shape:
Solid
Molecular weight:
382.45
Ref: TM-T6S0655
| 1mg | 47.00 € | ||
| 5mg | 94.00 € | ||
| 10mg | 172.00 € | ||
| 25mg | 276.00 € | ||
| 50mg | 420.00 € | ||
| 100mg | 606.00 € | ||
| 500mg | 1,252.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Avicularin
CAS:572-30-5
Avicularin reduces inflammation via ERK pathway in RAW 264.7 cells and hinders lipid buildup in …
Formula:
C20H18O11
Purity:
97.02% - 99.43%
Color and Shape:
White Powder
Molecular weight:
434.35
Ref: TM-T6S0117
| 1mg | 56.00 € | ||
| 5mg | 93.00 € | ||
| 10mg | 155.00 € | ||
| 25mg | 272.00 € | ||
| 1mL*10mM (DMSO) | 107.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Sauchinone
CAS:177931-17-8
Sauchinone: Treats infections, prevents liver fibrosis, reduces oxidative stress, and protects skin and vascular cells.
Formula:
C20H20O6
Purity:
100%
Color and Shape:
Solid
Molecular weight:
356.37
Ref: TM-T6S1572
| 1mg | 35.00 € | ||
| 5mg | 69.00 € | ||
| 10mg | 110.00 € | ||
| 25mg | 182.00 € | ||
| 50mg | 298.00 € | ||
| 100mg | 444.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Ravoxertinib
CAS:1453848-26-4
Ravoxertinib (GDC-0994) is an effective and orally available ERK1/2 inhibitor (IC50: 1.1/0.3 nM).
Formula:
C21H18ClFN6O2
Purity:
98% - 99.87%
Color and Shape:
Solid
Molecular weight:
440.86
Ref: TM-T6511
| 1mg | 40.00 € | ||
| 2mg | 51.00 € | ||
| 5mg | 83.00 € | ||
| 10mg | 94.00 € | ||
| 25mg | 171.00 € | ||
| 50mg | 276.00 € | ||
| 100mg | 412.00 € | ||
| 1mL*10mM (DMSO) | 93.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Bohemine
CAS:189232-42-6
Bohemine is a cyclin-dependent kinase inhibitor.
Formula:
C18H24N6O
Purity:
99.09% - 99.53%
Color and Shape:
Solid
Molecular weight:
340.42
Ref: TM-T2029
| 5mg | 34.00 € | ||
| 10mg | 50.00 € | ||
| 25mg | 83.00 € | ||
| 50mg | 136.00 € | ||
| 100mg | 204.00 € | ||
| 200mg | 301.00 € | ||
| 1mL*10mM (DMSO) | 34.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Tizaterkib
CAS:2097416-76-5
Tizaterkib (AZD-0364) is a potent and selective ERK2 inhibitor.
Formula:
C24H24F2N8O2
Purity:
99.24% - 99.6%
Color and Shape:
Solid
Molecular weight:
494.5
Ref: TM-T10429
| 1mg | 93.00 € | ||
| 2mg | 135.00 € | ||
| 5mg | 216.00 € | ||
| 10mg | 365.00 € | ||
| 25mg | 615.00 € | ||
| 50mg | 876.00 € | ||
| 1mL*10mM (DMSO) | 229.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Prosaptide TX14(A) acetate
Prosaptide TX14(A) acetate is a potent GPR37L1 and GPR37 agonist. Prosaptide Tx14(A) TFA increases both …
Formula:
C71H114N16O28
Purity:
95.29%
Color and Shape:
Solid
Molecular weight:
1639.76
Ref: TM-TP1970L
| 1mg | 144.00 € | ||
| 5mg | 343.00 € | ||
| 10mg | 512.00 € | ||
| 25mg | 824.00 € | ||
| 50mg | 1,116.00 € | ||
| 100mg | 1,529.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
AZD8330
CAS:869357-68-6
AZD8330 (ARRY-704) is a novel, selective, non-ATP competitive MEK 1/2 inhibitor with IC50 of 7 …
Formula:
C16H17FIN3O4
Purity:
98.72%
Color and Shape:
Solid
Molecular weight:
461.23
Ref: TM-T6083
| 1mg | 38.00 € | ||
| 5mg | 79.00 € | ||
| 10mg | 119.00 € | ||
| 25mg | 198.00 € | ||
| 50mg | 299.00 € | ||
| 1mL*10mM (DMSO) | 80.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
β,β-Dimethylacrylshikonin
CAS:24502-79-2
β,β-Dimethylacrylshikonin (Dimethylacrylshikonin) is a promising agent for developing an improved strategy for radiotherapy against tumors.
Formula:
C21H22O6
Purity:
93.42% - 98.86%
Color and Shape:
Solid
Molecular weight:
370.4
Ref: TM-T3S2344
| 20mg | 126.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Gypenoside L
CAS:94987-09-4
Gypenoside L inhibits autophagic flux and induces cell death in human esophageal cancer cells through …
Formula:
C42H72O14
Purity:
99.42% - 99.65%
Color and Shape:
Solid
Molecular weight:
801.01
Ref: TM-TN1721
| 1mg | 124.00 € | ||
| 5mg | 290.00 € | ||
| 10mg | 369.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
