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CFTR

CFTR

CFTR is a chloride channel protein that regulates the transport of chloride and bicarbonate ions across epithelial cell membranes, playing a crucial role in maintaining fluid balance in tissues. Mutations in the CFTR gene lead to cystic fibrosis, a genetic disorder characterized by the production of thick mucus that can clog airways and lead to severe respiratory and digestive problems. At CymitQuimica, we provide a selection of CFTR modulators to support your research in cystic fibrosis, ion transport, and genetic disorders.

Found 64 products of "CFTR"

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  • Glibenclamide potassium
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    Glibenclamide potassium

    CAS:
    <p>Glibenclamide potassium, a more soluble form of Glibenclamide, exists as anhydrous and hydrate salts.</p>
    Formula:C23H27ClKN3O5S
    Color and Shape:Solid
    Molecular weight:532.09

    Ref: TM-T72272

  • CFTR corrector 2
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    CFTR corrector 2

    CAS:
    <p>CFTR corrector 2 (FDL169) is a novel and potent CFTR corrector for treating cystic fibrosis (CF) patients who carry the F508del mutation.</p>
    Formula:C27H23FN4O4
    Purity:99.66%
    Color and Shape:Solid
    Molecular weight:486.49

    Ref: TM-T5312

  • Lubiprostone
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    Lubiprostone

    CAS:
    <p>Lubiprostone (RU-0211), an activator of ClC-2 chloride channels, is used in the therapy of idiopathic chronic constipation.</p>
    Formula:C20H32F2O5
    Purity:97.31% - 98.54%
    Color and Shape:White Odorless Crystals Or Crystalline Powder
    Molecular weight:390.46

    Ref: TM-T6307

  • IOWH-032
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    IOWH-032

    CAS:
    <p>IOWH-032 (IOWH032) , a synthetic CFTR inhibitor, has been investigated for the treatment of cholera, diarrhea, and secretory diarrhea.</p>
    Formula:C22H15Br2N3O4
    Purity:98.92% - ≥95%
    Color and Shape:Solid
    Molecular weight:545.18

    Ref: TM-T2486

  • KM11060
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    KM11060

    CAS:
    <p>KM11060 is a novel corrector of the F508del-CFTR trafficking defect, Correcting F508del-CFTR trafficking, increasing the amount of functional CFTR at the plasma</p>
    Formula:C19H17Cl2N3O2S
    Purity:98.86%
    Color and Shape:Solid
    Molecular weight:422.33

    Ref: TM-T3135

  • Icenticaftor
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    Icenticaftor

    CAS:
    <p>Icenticaftor (QBW251) is an orally active potentiator of CFTR channel.</p>
    Formula:C12H13F6N3O3
    Purity:99.76%
    Color and Shape:Solid
    Molecular weight:361.24

    Ref: TM-T9499

  • CFTR(inh)-172
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    CFTR(inh)-172

    CAS:
    <p>CFTR(inh)-172 (CFTR Inhibitor-172) is a voltage-independent, selective CFTR inhibitor.</p>
    Formula:C18H10F3NO3S2
    Purity:98% - 99.72%
    Color and Shape:Solid
    Molecular weight:409.4

    Ref: TM-T2355

  • Nesolicaftor
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    Nesolicaftor

    CAS:
    <p>Nesolicaftor (PTI-428) specifically enhances cystic fibrosis transmembrane conductance regulator protein synthesis.</p>
    Formula:C18H18N4O4
    Purity:99.79%
    Color and Shape:Solid
    Molecular weight:354.36

    Ref: TM-T16681

  • Tezacaftor
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    Tezacaftor

    CAS:
    <p>Tezacaftor (VX661) is a small molecule that can be used as a corrector of the cystic fibrosis transmembrane conductance regulator (CFTR) gene function.</p>
    Formula:C26H27F3N2O6
    Purity:98.84% - >99.99%
    Color and Shape:Solid
    Molecular weight:520.5

    Ref: TM-T2263

  • SRI-41315
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    SRI-41315

    CAS:
    <p>SRI-41315 is an eRF1 degrader that acts as a molecular glue at the ribosomal decoding center.SRI-41315 induces extended pauses at the termination codon.</p>
    Formula:C22H19N3O2
    Purity:99.87%
    Color and Shape:Solid
    Molecular weight:357.41

    Ref: TM-T61306

  • Steviol
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    Steviol

    CAS:
    <p>1.</p>
    Formula:C20H30O3
    Purity:98% - 99.92%
    Color and Shape:Solid
    Molecular weight:318.45

    Ref: TM-T2S1837

  • GLPG-3221
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    GLPG-3221

    CAS:
    <p>GLPG-3221, a potent oral CFTR corrector for cystic fibrosis treatment, has an EC50 of 105 nM.</p>
    Formula:C30H37F3N2O6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:578.62

    Ref: TM-T13704

  • CFTR corrector 9
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    CFTR corrector 9

    CAS:
    <p>CFTR corrector 9 is a CF modulator used to research cystic fibrosis and related disorders.</p>
    Formula:C16H14N2O4
    Purity:98.24%
    Color and Shape:Solid
    Molecular weight:298.29

    Ref: TM-T60653

  • Posenacaftor
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    Posenacaftor

    CAS:
    <p>Posenacaftor (PTI-801) regulates CFTR protein for cystic fibrosis research.</p>
    Formula:C27H27NO5
    Color and Shape:Solid
    Molecular weight:445.51

    Ref: TM-T62630

  • Posenacaftor sodium
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    Posenacaftor sodium

    CAS:
    <p>Posenacaftor (PTI-801) sodium, a CFTR modulator for CF research, corrects CFTR protein folding and trafficking.</p>
    Formula:C27H27NNaO5
    Color and Shape:Solid
    Molecular weight:468.505

    Ref: TM-T36519

  • Corrector C4
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    Corrector C4

    CAS:
    <p>Corrector C4, a corrector commonly used to study cystic fibrosis mutants, works by alleviating the interaction between CFTR transmembrane domain mutants and</p>
    Formula:C21H17ClN4O2S2
    Purity:98.36%
    Color and Shape:Solid
    Molecular weight:456.97

    Ref: TM-T31014

  • Galicaftor
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    Galicaftor

    CAS:
    <p>ABBV-2222 is a CFTR corrector which is studied for the treatment of cystic fibrosis (CF).</p>
    Formula:C28H21F4NO7
    Purity:98%
    Color and Shape:Solid
    Molecular weight:559.46

    Ref: TM-T22252

  • (R)-Posenacaftor sodium
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    (R)-Posenacaftor sodium

    CAS:
    <p>(R)-Posenacaftor sodium is a modulator for correcting cystic fibrosis protein folding.</p>
    Formula:C27H27NNaO5
    Color and Shape:Solid
    Molecular weight:468.505

    Ref: TM-T35925

  • (R)-Olacaftor
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    (R)-Olacaftor

    CAS:
    <p>(R)-Olacaftor (VX-440) is a CFTR modulator with promise for researching cystic fibrosis.</p>
    Formula:C29H34FN3O4S
    Color and Shape:Solid
    Molecular weight:539.66

    Ref: TM-T72860

  • Ivacaftor-D9
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    Ivacaftor-D9

    CAS:
    <p>CTP-656, a cystic fibrosis transmembrane conductance regulator (CFTR) channel activator, is used potentially for the treatment of cystic fibrosis.</p>
    Formula:C24H19D9N2O3
    Color and Shape:Solid
    Molecular weight:401.55

    Ref: TM-T27098