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CFTR

CFTR

CFTR is a chloride channel protein that regulates the transport of chloride and bicarbonate ions across epithelial cell membranes, playing a crucial role in maintaining fluid balance in tissues. Mutations in the CFTR gene lead to cystic fibrosis, a genetic disorder characterized by the production of thick mucus that can clog airways and lead to severe respiratory and digestive problems. At CymitQuimica, we provide a selection of CFTR modulators to support your research in cystic fibrosis, ion transport, and genetic disorders.

Found 66 products of "CFTR"

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  • CFTR corrector 18
    Targetmol
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    CFTR corrector 18

    CAS:
    CFTRcorrector 18 (Compound I-99) acts as a modulator of the cystic fibrosis transmembrane conductance regulator (CFTR). It enhances the processing and trafficking of CFTR, thereby increasing the amount of CFTR present on the cell surface. CFTRcorrector 18 holds potential for research in cystic fibrosis (CF).
    Formula:C38H40N6O5S
    Color and Shape:Solid
    Molecular weight:692.826

    Ref: TM-T206874

    10mg
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  • Crinecerfont tosylate
    Targetmol
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    Crinecerfont tosylate

    CAS:
    Crinecerfont tosylate is an effective oral CRF1 receptor antagonist. It is applicable to studies involving congenital adrenal hyperplasia (CAH).
    Formula:C34H36ClFN2O4S2
    Color and Shape:Solid
    Molecular weight:655.242

    Ref: TM-T205414

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  • CFTR corrector 15
    Targetmol
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    CFTR corrector 15

    CAS:
    CFTR Corrector 15 (Compound 4172) serves as a corrector for cystic fibrosis transmembrane conductance regulator (CFTR). When used in combination with VX-809, it addresses the folding defects of F508del-CFTR. CFTR Corrector 15 is also applicable in the research of cystic fibrosis.
    Formula:C24H22ClN5O2S
    Color and Shape:Solid
    Molecular weight:479.98

    Ref: TM-T89966

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    50mg
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  • CFTR corrector 16
    Targetmol
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    CFTR corrector 16

    CAS:
    CFTRcorrector 16 (Compound 39) is a corrector of the cystic fibrosis transmembrane conductance regulator (CFTR), utilized in the research of cystic fibrosis disease.
    Formula:C27H26ClN5O2S
    Color and Shape:Solid
    Molecular weight:520.05

    Ref: TM-T200113

    25mg
    1,969.00€
    50mg
    2,582.00€
    100mg
    3,436.00€
  • CFTR corrector 17
    Targetmol
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    CFTR corrector 17

    CAS:
    CFTRcorrector 17 (example 17) is a regulator of the cystic fibrosis transmembrane conductance regulator (CFTR). It is utilized in the study of diseases mediated by CFTR.
    Formula:C18H15FN2O2
    Color and Shape:Solid
    Molecular weight:310.32

    Ref: TM-T201013

    25mg
    1,458.00€
    50mg
    1,839.00€
    100mg
    2,322.00€
  • ARN23765
    Targetmol
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    ARN23765

    CAS:
    ARN23765 is an F508del-CFTR corrector with an EC50 of 38 pM in human bronchial epithelial cells. It enhances the maturation and function of F508del-CFTR at the cell membrane, influencing ion transport and secretion, thereby addressing the pathological mechanisms of cystic fibrosis (CF).
    Formula:C30H22F5N3O6
    Color and Shape:Solid
    Molecular weight:615.504

    Ref: TM-T205032

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