CFTR
CFTR is a chloride channel protein that regulates the transport of chloride and bicarbonate ions across epithelial cell membranes, playing a crucial role in maintaining fluid balance in tissues. Mutations in the CFTR gene lead to cystic fibrosis, a genetic disorder characterized by the production of thick mucus that can clog airways and lead to severe respiratory and digestive problems. At CymitQuimica, we provide a selection of CFTR modulators to support your research in cystic fibrosis, ion transport, and genetic disorders.
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PG01
CAS:853138-65-5
PG01 is a potent CFTR Cl-channel potentiator, effective against ΔF508 (Ka 0.3 μM), and also …
Formula:
C28H29N3O2
Purity:
99.87%
Color and Shape:
Solid
Molecular weight:
439.55
Ref: TM-T16516
| 1mg | 121.00 € | ||
| 5mg | 351.00 € | ||
| 10mg | 527.00 € | ||
| 25mg | 852.00 € | ||
| 50mg | 1,143.00 € | ||
| 100mg | 1,559.00 € | ||
| 500mg | 3,121.00 € | ||
| 1mL*10mM (DMSO) | 348.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
UCCF-853
CAS:625458-06-2
UCCF-853 is a small-molecule CFTR modulator that can be used to study cystic fibrosis.
Formula:
C14H8ClF3N2O
Purity:
100%
Color and Shape:
Solid
Molecular weight:
312.67
Ref: TM-T29041
| 1mg | 38.00 € | ||
| 2mg | 49.00 € | ||
| 5mg | 80.00 € | ||
| 10mg | 111.00 € | ||
| 25mg | 179.00 € | ||
| 50mg | 267.00 € | ||
| 100mg | 396.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
VRT-532
CAS:38214-71-0
VRT-532 (CFpot-532) is an effective modulator of CFTR and is commonly used in studies of …
Formula:
C16H14N2O
Purity:
100% - 99.89%
Color and Shape:
Solid
Molecular weight:
250.3
Ref: TM-T29114
| 1mg | 150.00 € | ||
| 5mg | 363.00 € | ||
| 10mg | 546.00 € | ||
| 25mg | 904.00 € | ||
| 50mg | 1,235.00 € | ||
| 100mg | 1,625.00 € | ||
| 1mL*10mM (DMSO) | 327.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
CFTR corrector 8
CAS:1918142-35-4
CFTR corrector 8: potent for cystic fibrosis research, modulates CFTR protein.
Formula:
C29H27F2NO7
Purity:
99.58%
Color and Shape:
Solid
Molecular weight:
539.52
Ref: TM-T63806
| 1mg | 80.00 € | ||
| 5mg | 172.00 € | ||
| 10mg | 258.00 € | ||
| 25mg | 522.00 € | ||
| 50mg | 820.00 € | ||
| 100mg | 1,345.00 € | ||
| 1mL*10mM (DMSO) | 216.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
Bamocaftor
CAS:2204245-48-5
Bamocaftor corrects CFTR in CF, restoring F508del-CFTR function, used with tezacaftor and VX-561 for F508del/MF …
Formula:
C28H32F3N5O4S
Purity:
99.85%
Color and Shape:
Solid
Molecular weight:
591.65
Ref: TM-T30293
| 1mg | 347.00 € | ||
| 5mg | 828.00 € | ||
| 10mg | 1,138.00 € | ||
| 25mg | 1,662.00 € | ||
| 50mg | 2,270.00 € | ||
| 100mg | 3,047.00 € | ||
| 1mL*10mM (DMSO) | 1,218.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
DNDS
CAS:3709-43-1
DNDS is a channel blocker of voltage-dependent cystic fibrosis transmembrane conductance regulator (CFTR).
Formula:
C14H8N2Na2O10S2
Purity:
99.88%
Color and Shape:
Physical Description White Powder (Ntp 1992)
Molecular weight:
474.33
Ref: TM-T20341
| 1g | 34.00 € | ||
| 1mL*10mM (DMSO) | 47.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
BPO-27 racemate
CAS:1314873-02-3
BPO-27 racemate (BPO-27 (racemate)) is an effective CFTR inhibitor with IC50 of 8 nM.
Formula:
C26H18BrN3O6
Purity:
98.19%
Color and Shape:
Solid
Molecular weight:
548.34
Ref: TM-T10591
| 1mg | 45.00 € | ||
| 5mg | 113.00 € | ||
| 10mg | 169.00 € | ||
| 25mg | 271.00 € | ||
| 50mg | 395.00 € | ||
| 100mg | 545.00 € | ||
| 200mg | 731.00 € | ||
| 1mL*10mM (DMSO) | 130.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
CRF1 receptor antagonist-1
CAS:2635364-30-4
CRF1 Receptor Antagonist-1 (Compound 2), a CRF1 receptor antagonist, is utilized in research pertaining to …
Formula:
C27H28ClFN2O2S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
499.04
Ref: TM-T79793
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 7 Jan 2025
(R)-Elexacaftor
CAS:2229860-99-3
(R)-Elexacaftor, an enantiomer of Elexacaftor, functions as a modulator of the cystic fibrosis transmembrane conductance …
Formula:
C26H34F3N7O4S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
597.65
Ref: TM-T78240
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 7 Jan 2025
CFTR corrector 12
CAS:958941-60-1
CFTR corrector 12 is a CFTR corrector that rescues all mutant proteins except M760R ABCA3 …
Formula:
C19H21ClN4O2S2
Purity:
99.78%
Color and Shape:
Solid
Molecular weight:
436.98
Ref: TM-T79578
| 1mg | 182.00 € | ||
| 5mg | 451.00 € | ||
| 10mg | 646.00 € | ||
| 25mg | 1,007.00 € | ||
| 50mg | 1,390.00 € | ||
| 100mg | 1,837.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
CFTR corrector 4
CAS:1918142-34-3
Potent, oral CFTR corrector 4 targets cystic fibrosis, increasing cell surface CFTR levels.
Formula:
C29H27F2NO7
Purity:
98.43%
Color and Shape:
Solid
Molecular weight:
539.52
Ref: TM-T10776
| 1mg | 74.00 € | ||
| 5mg | 171.00 € | ||
| 10mg | 258.00 € | ||
| 25mg | 523.00 € | ||
| 50mg | 737.00 € | ||
| 100mg | 1,049.00 € | ||
| 500mg | 2,097.00 € | ||
| 1mL*10mM (DMSO) | 201.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
