TRP/TRPV Channel
TRP (Transient Receptor Potential) channels, including the TRPV subfamily, are a group of ion channels involved in various sensory processes, such as temperature sensation, pain perception, and osmoregulation. TRP channels are widely expressed in different tissues and play a role in physiological responses to environmental stimuli. The TRPV channels, in particular, are involved in detecting temperature changes and are implicated in conditions such as chronic pain, inflammation, and cancer. At CymitQuimica, we offer a comprehensive range of TRP/TRPV channel modulators to support your research in sensory biology, pain management, and signal transduction.
Found 96 products of "TRP/TRPV Channel"
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AC1903
CAS:AC1903 is a specific inhibitor of TRPC5 channel, and has been shown to suppress severe proteinuria and prevent podocyte loss.Formula:C19H17N3OPurity:98.45%Color and Shape:SolidMolecular weight:303.36JNJ-28583113
CAS:JNJ-28583113 is a TRPM2 antagonist, inducing phosphorylation of GSK3α and β subunits, protecting cells from oxidative stress-induced cell death.Formula:C19H21F3N2O2Purity:98.57%Color and Shape:SolidMolecular weight:366.38Ref: TM-T74779
1mg89.00€5mg204.00€10mg254.00€25mg409.00€50mg624.00€100mg795.00€200mg1,103.00€1mL*10mM (DMSO)225.00€SAR7334
CAS:SAR7334 (TRCP6-IN-1) is a potent and specific inhibitor of TRPC6(IC50 of 7.9 nM).Formula:C21H22ClN3OPurity:99.62% - 99.71%Color and Shape:SolidMolecular weight:367.87Ref: TM-T12849
1mg67.00€2mg88.00€5mg152.00€10mg236.00€25mg295.00€50mg349.00€100mg439.00€200mg628.00€1mL*10mM (DMSO)166.00€JYL 1421
CAS:JYL 1421 (SC 0030) is an antagonist of TRPV1 receptor (IC50 = 8 nM).Formula:C20H26FN3O2S2Purity:98.83%Color and Shape:SolidMolecular weight:423.57Ref: TM-T15634
1mg66.00€5mg177.00€10mg289.00€25mg580.00€50mg888.00€100mg1,414.00€200mg1,882.00€1mL*10mM (DMSO)170.00€Asivatrep
CAS:Asivatrep (PAC14028) is a selective and potent antagonist of transient receptor potential vanilloid subtype 1 (TRPV1) for the study of atopic dermatitis.Formula:C21H22F5N3O3SPurity:95.13%Color and Shape:SolidMolecular weight:491.48TRPV4 agonist-1
CAS:TRPV4 agonist-1 is an agonist of TRPV4 (EC50: 60 nM in the hTRPV4 Ca2+ assay).Formula:C25H23ClF2N4O2Purity:98%Color and Shape:SolidMolecular weight:484.93TRPC6-PAM-C20
CAS:TRPC6-PAM-C20, a selective enhancer for TRPC6, boosts calcium in HEK cells and OAG-related platelet clumping, EC50: 2.37μM.Formula:C22H21NO4Purity:98.16%Color and Shape:SolidMolecular weight:363.41D-3263 hydrochloride
CAS:D-3263 hydrochloride (D3263 HCl salt) is enteric-coated, orally bioavailable transient receptor potential melatonin member 8 (TRPM8) agonist.
Formula:C21H32ClN3O3Purity:99.93%Color and Shape:SolidMolecular weight:409.95TRPV3 antagonist 74a
CAS:TRPV3 antagonist 74a (TRPV3 74a) is a specific TRPV3 antagonist for the study of neurological disorders.Formula:C17H17F3N2O2Purity:≥98.0%Color and Shape:SolidMolecular weight:338.32GSK1702934A
CAS:GSK1702934A is a TRPC3 agonist with pro-arrhythmic and positive inotropic effects and is used in the study of diabetes mellitus.Formula:C22H25N3O2SPurity:98.15%Color and Shape:SolidMolecular weight:395.52N-Oleoyl Valine
CAS:N-Oleoyl valine, an N-acyl amine, antagonizes TRPV3 for thermoregulation; rises post-cold exposure; elevates in mouse lung injury.Formula:C23H43NO3Molecular weight:381.59TRPM4-IN-2
CAS:NBA, or TRPM4-IN-2, is a potent TRPM4 inhibitor with IC50 of 0.16 μM, used in prostate and colorectal cancer research.Formula:C19H14ClNO4Purity:99.21%Color and Shape:SolidMolecular weight:355.77AM12
CAS:AM12 inhibits Lanthanide-evoked TRPC5 activity (IC50: 0.28 μM).Formula:C15H9BrO5Purity:98%Color and Shape:SolidMolecular weight:349.13RN9893
CAS:RN9893 is a selective and potent TRPV4 receptor antagonist with IC50 values of 320, 420 and 660 nM for TRPV4 receptors in mouse, human and rat, respectively.Formula:C21H23F3N4O5SPurity:99.99%Color and Shape:SolidMolecular weight:500.49HC-070
CAS:HC-070 is a TRPC5 and TRPC4 antagonist (IC50 = 9.3 nM and 46 nM).Formula:C22H20Cl2N4O4Purity:98.48%Color and Shape:SolidMolecular weight:475.32Ref: TM-T15465
1mg84.00€5mg160.00€10mg236.00€25mg406.00€50mg572.00€100mg772.00€200mg1,035.00€1mL*10mM (DMSO)165.00€ABT 102
CAS:ABT 102 (CHEMBL398338) is a selective antagonist of transient receptor potential vanilloid 1 (TRPV1) receptor.Formula:C21H24N4OPurity:98.38% - 99.86%Color and Shape:SolidMolecular weight:348.44Ref: TM-T29522
1mg109.00€5mg235.00€10mg349.00€25mg532.00€50mg745.00€100mg999.00€200mg1,333.00€1mL*10mM (DMSO)245.00€Olvanil
CAS:Olvanil (N-Vannilyloleoylamide) is a vanilloid receptor agonist with EC50 of 0.7nM.Formula:C26H43NO3Purity:99.58%Color and Shape:SolidMolecular weight:417.62Ref: TM-T23106
2mg34.00€5mg49.00€10mg75.00€25mg145.00€50mg236.00€100mg385.00€200mg560.00€1mL*10mM (DMSO)50.00€Elismetrep
CAS:Elismetrep (MT-8554) is an orally available TRPM8 inhibitor with potential analgesic activity for the study of vasomotor symptoms in postmenopausal women.Formula:C27H21F3N2O5SPurity:99.37% - 99.93%Color and Shape:SolidMolecular weight:542.53TC-I 2014
CAS:TC-I 2014 shows antiallodynic properties in pain models.Formula:C23H19F6N3OPurity:99.07%Color and Shape:SolidMolecular weight:467.41Ref: TM-T17006
1mg57.00€5mg120.00€10mg192.00€25mg385.00€50mg620.00€100mg1,018.00€200mg1,378.00€1mL*10mM (DMSO)126.00€MSP3
CAS:MSP3 is an agonist of TRPV1 (EC50 = 0.87 μM) and shows antinociceptive and neuroprotective effects.Formula:C16H19NO3SPurity:99.89%Color and Shape:SolidMolecular weight:305.39Ref: TM-T28118
2mg33.00€5mg50.00€10mg80.00€25mg161.00€50mg243.00€100mg358.00€200mg505.00€1mL*10mM (DMSO)71.00€
