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Potassium Channel

Potassium Channel

Potassium channels are a diverse group of membrane proteins that facilitate the flow of potassium ions (K+) across the cell membrane. These channels play a crucial role in maintaining the resting membrane potential, regulating cell volume, and controlling the excitability of neurons and muscle cells. Potassium channels are involved in various physiological processes, including cardiac rhythm regulation, insulin secretion, and neurotransmitter release. Dysregulation of potassium channels is linked to conditions such as arrhythmias, epilepsy, and hypertension. At CymitQuimica, we offer a wide range of potassium channel modulators to support your research in electrophysiology, cardiovascular health, and neurobiology.

Found 276 products of "Potassium Channel"

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  • MK-0448

    CAS:
    <p>MK-0448 is a novel and selective blocker of the Kv1.5 (KCNA5) channel, a key channel involved in cardiac repolarization current I Kur.</p>
    Formula:C24H21FN4O2S
    Purity:99.25% - 99.79%
    Color and Shape:Solid
    Molecular weight:448.51
  • CyPPA

    CAS:
    <p>CyPPA enhances SK channels, reducing firing rate and extending apamin-sensitive afterhyperpolarization.</p>
    Formula:C16H23N5
    Purity:99.88%
    Color and Shape:Solid
    Molecular weight:285.39
  • Sipatrigine

    CAS:
    <p>Sipatrigine (619C89) is an inhibitor of glutamate release, TREK ion channels, TRESK channels, sodium channels, and calcium channels.</p>
    Formula:C15H16Cl3N5
    Purity:98.64% - 99.77%
    Color and Shape:Solid
    Molecular weight:372.68
  • RL648_81

    CAS:
    <p>RL648_81 is a selective activator of KCNQ2/3 channels (EC50 = 190 nM). RL648_81 can be used in studies about neuronal hyperexcitability neurologic disorders.</p>
    Formula:C17H17F4N3O2
    Purity:99.82%
    Color and Shape:Solid
    Molecular weight:371.33
  • SKA-111

    CAS:
    <p>SKA-111 activates KCa3.1 potassium channels, modulates membrane potential in endothelial cells, and dilates rat coronary arteries.</p>
    Formula:C12H10N2S
    Purity:99.9%
    Color and Shape:Solid
    Molecular weight:214.29
  • ZTZ240

    CAS:
    <p>ZTZ240 is a KCNQ2 channel activator used in the study of epilepsy.</p>
    Formula:C12H8ClFN2O
    Purity:99.89%
    Color and Shape:Solid
    Molecular weight:250.66
  • ZM 226600

    CAS:
    <p>ZM 226600 is an ATP-sensitive potassium channel opener with an EC50 value of 500 nM. ZM226600 has an inhibitory effect on spontaneous bladder activity.</p>
    Formula:C16H14F3NO4S
    Purity:99.87%
    Color and Shape:Solid
    Molecular weight:373.35
  • PD-118057

    CAS:
    <p>PD-118057, a potent hERG activator, may treat long QT syndrome and heart failure without hERG activity inhibition.</p>
    Formula:C21H17Cl2NO2
    Purity:99.16% - 99.97%
    Color and Shape:Solid
    Molecular weight:386.27
  • UK 66914

    CAS:
    <p>UK 66914 is a K(+) channel blocker for the study of cardiac arrhythmias.</p>
    Formula:C18H24N4O3S
    Purity:99.75%
    Color and Shape:Solid
    Molecular weight:376.47
  • (+)-KCC2 blocker 1

    CAS:
    <p>(+)-KCC2 blocker 1 is a selective blocker of KCC2 (IC50 = 0.4 μM).</p>
    Formula:C22H25NO5S
    Purity:99.88%
    Color and Shape:Solid
    Molecular weight:415.5
  • GW 542573X

    CAS:
    <p>GW 542573X is a potent and selective small molecule Ca2+-activated K+ 2 (SK2) channel activator.GW 542573X induces a leftward shift in the Ca2+ response curve</p>
    Formula:C19H28N2O5
    Purity:99.91%
    Color and Shape:Solid
    Molecular weight:364.44
  • XE991

    CAS:
    <p>XE991 is a Kv7 (KCNQ) channel blocker.XE 991 dihydrochloride inhibits Kv7.1 (KCNQ1) and M-current and can be used in the study of neurological disorders.</p>
    Formula:C26H20N2O
    Purity:98.87%
    Color and Shape:Solid
    Molecular weight:376.45
  • TWIK-1/TREK-1-IN-3

    CAS:
    <p>TWIK-1/TREK-1-IN-3 is a potassium channel TREK-1 inhibitor TWIK-1/TREK-1-IN-3 has antidepressant activity and can be used to study depression.</p>
    Formula:C19H27F3N2O2
    Purity:99.04%
    Color and Shape:Solid
    Molecular weight:372.43
  • IKs124

    CAS:
    <p>IKs124 is a KCNE2/KCNQ1 potassium channel blocker, for hKCNE1 and hKCNE3, and can be used to study peptic ulcers.</p>
    Formula:C18H26N2O3S
    Purity:99.53%
    Color and Shape:Solid
    Molecular weight:350.48
  • KT-362 fumarate

    CAS:
    <p>KT-362 fumarate, a novel antagonist of Ca, K, and Na channels, induces vasodilation and relaxes rabbit arterial strips.</p>
    Formula:C26H32N2O7S
    Purity:99.75% - 99.98%
    Color and Shape:Solid
    Molecular weight:516.61
  • JNJ-26489112

    CAS:
    <p>JNJ-26489112 is a CNS-active agent and an inhibitor of voltage-gated Na+ channels and N-type Ca2+ channels.</p>
    Formula:C9H11ClN2O4S
    Purity:99.31%
    Color and Shape:Solid
    Molecular weight:278.71
  • Linaprazan

    CAS:
    <p>Linaprazan (AZD0865) inhibits gastric H+,K+-ATPase by K+-competitive binding with an IC50 of 1.0 μM.</p>
    Formula:C21H26N4O2
    Purity:99.54%
    Color and Shape:Solid
    Molecular weight:366.46
  • DPO-1

    CAS:
    <p>DPO-1 可以高效抑制电压门控钾离子通道Kv1.5,也可以阻断超快速延迟整流钾电流。它能够预防房性心律失常。</p>
    Formula:C22H29OP
    Purity:99.78%
    Color and Shape:Solid
    Molecular weight:340.44
  • Clobutinol hydrochloride

    CAS:
    <p>Clobutinol hydrochloride, an antitussive agent, influences heart rate and blood pressure, and is utilized in cough-related research [1] [2] [3].</p>
    Formula:C14H23Cl2NO
    Purity:98%
    Color and Shape:Solid
    Molecular weight:292.25
  • VU0463271

    CAS:
    <p>VU0463271: KCC2 antagonist, IC50 61 nM, &gt;100x selective over NKCC1, inactive on other GPCRs, channels, transporters.</p>
    Formula:C19H18N4OS2
    Purity:97.84% - 99.55%
    Color and Shape:Solid
    Molecular weight:382.5