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Potassium Channel

Potassium Channel

Potassium channels are a diverse group of membrane proteins that facilitate the flow of potassium ions (K+) across the cell membrane. These channels play a crucial role in maintaining the resting membrane potential, regulating cell volume, and controlling the excitability of neurons and muscle cells. Potassium channels are involved in various physiological processes, including cardiac rhythm regulation, insulin secretion, and neurotransmitter release. Dysregulation of potassium channels is linked to conditions such as arrhythmias, epilepsy, and hypertension. At CymitQuimica, we offer a wide range of potassium channel modulators to support your research in electrophysiology, cardiovascular health, and neurobiology.

Found 276 products of "Potassium Channel"

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  • KS176

    CAS:
    <p>KS176: selective BCRP inhibitor, potent against breast cancer drug resistance; ineffective on P-gp, MRP1.</p>
    Formula:C22H19N3O5
    Purity:99.61% - 99.61%
    Color and Shape:Solid
    Molecular weight:405.4
  • 5-Hydroxydecanoate sodium

    CAS:
    <p>5-Hydroxydecanoate sodium: KATP channel blocker, IC50 ~30μM; mitochondrial substrate; antioxidant.</p>
    Formula:C10H19NaO3
    Purity:99.24% - 99.89%
    Color and Shape:Solid
    Molecular weight:210.25
  • VU0810464

    CAS:
    <p>VU0810464 is a non-ureaG protein-gated inwardly-rectifying potassium channels (GIRK, Kir3) activator.</p>
    Formula:C18H21ClFN3O
    Purity:99.62%
    Color and Shape:Solid
    Molecular weight:349.83
  • Loureirin B

    CAS:
    <p>Loureirin B suppresses fibrosis by modulating MMPs/TIMPs, hindering fibroblast growth, and targeting TGF-β1/Smad2/3 pathway.</p>
    Formula:C18H20O5
    Purity:99.33% - 99.86%
    Color and Shape:Solid
    Molecular weight:316.35
  • Mitiglinide calcium hydrate

    CAS:
    <p>Mitiglinide calcium hydrate (S-21403 calcium hydrate) is a drug for the treatment of type 2 diabetes.</p>
    Formula:C38H52CaN2O8
    Purity:98.97% - 99.96%
    Color and Shape:White Solid
    Molecular weight:704.91
  • A2793

    CAS:
    <p>A2793 is a dual inhibitor of TWIK-associated acid-sensitive K+ channel 1 (TASK-1)/TRESK, with an IC50 for mTRESK of 6.8 μM.</p>
    Formula:C13H12ClNO3
    Purity:98.54%
    Color and Shape:Solid
    Molecular weight:265.69
  • O-Nornuciferine

    CAS:
    <p>O-Nornuciferine reveals distinct in vitro hERG blockages measured in HEK293 cells with the IC50 value of 2.89 uM.</p>
    Formula:C18H19NO2
    Purity:99.86%
    Color and Shape:Solid
    Molecular weight:281.35
  • ML213

    CAS:
    <p>ML213 (CID-3111211) is a selective activator of Kv7.2 (KCNQ2) and Kv7.4 (KCNQ4) channels, enhances Kv7.2 and Kv7.4 channels with EC50s of 230 and 510 nM,</p>
    Formula:C17H23NO
    Purity:>99.99%
    Color and Shape:Solid
    Molecular weight:257.37
  • Levcromakalim

    CAS:
    <p>Levcromakalim (BRL 38227) is an activator of the ATP-sensitive K+ channel.</p>
    Formula:C16H18N2O3
    Purity:99.74%
    Color and Shape:Solid
    Molecular weight:286.33
  • NS 11021

    CAS:
    <p>NS 11021 (NS11021) , a novel opener of large-conductance Ca(2+)-activated K(+) channels</p>
    Formula:C16H9BrF6N6S
    Purity:97.26%
    Color and Shape:Solid
    Molecular weight:511.24
  • Tetraethylammonium bromide

    CAS:
    <p>Tetraethylammonium bromide (TEA bromide) can selectively block potassium channels.</p>
    Formula:C8H20BrN
    Purity:98%
    Color and Shape:White Solid
    Molecular weight:210.16
  • ML133 hydrochloride

    CAS:
    <p>ML133 hydrochloride (ML133 HCl) is a selective potassium channel inhibitor for Kir2.1, has no effect on Kir1.1 and weak activity for Kir4.1 and Kir7.1.</p>
    Formula:C19H19NO·HCl
    Purity:99.48%
    Color and Shape:Solid
    Molecular weight:313.82
  • SKF-96365 hydrochloride

    CAS:
    <p>SKF-96365 hydrochloride (SKF96365) , a SOCE inhibitor, exhibits potent anti-neoplastic activity by inducing cell-cycle arrest and apoptosis in colorectal Y</p>
    Formula:C22H27ClN2O3
    Purity:99.47% - 99.92%
    Color and Shape:Solid
    Molecular weight:402.91
  • Rimtuzalcap

    CAS:
    <p>Rimtuzalcap (CAD-1883), a selective modulator for SK channels, may treat movement disorders like SCA and ET.</p>
    Formula:C18H24F2N6O
    Purity:99.64%
    Color and Shape:Solid
    Molecular weight:378.42
  • A2764 dihydrochloride

    CAS:
    <p>A2764 dihydrochloride is a highly selective inhibitor of TRESK.</p>
    Formula:C15H21Cl3N2O
    Purity:99.05%
    Color and Shape:Solid
    Molecular weight:351.7
  • (±)-Naringenin

    CAS:
    <p>(±)-Naringenin (Naringenine) is a natural product.</p>
    Formula:C15H12O5
    Purity:98.06%
    Color and Shape:Solid
    Molecular weight:272.25
  • Dihydroberberine

    CAS:
    <p>Dihydroberberine has anti-atherosclerotic, anti-inflammatory, hypolipidemic and antitumor activities.</p>
    Formula:C20H19NO4
    Purity:93.77%
    Color and Shape:Solid
    Molecular weight:337.37
  • Nateglinide

    CAS:
    <p>Nateglinide is an oral drug for type 2 diabetes, stimulating insulin release; may cause rare acute liver injury.</p>
    Formula:C19H27NO3
    Purity:99.93% - 99.94%
    Color and Shape:White Crystalline Powder
    Molecular weight:317.42
  • Guanosine 5'-diphosphate

    CAS:
    <p>Guanosine 5'-diphosphate (GDP) as Potential Iron Mobilizer, Preventing the Hepcidin-Ferroportin Interaction and Modulating the Interleukin-6/Stat-3 Pathway.</p>
    Formula:C10H15N5O11P2
    Purity:98.46% - 99.52%
    Color and Shape:Solid
    Molecular weight:443.2
  • ML 297

    CAS:
    <p>ML 297 is a selective Kir3.1/3.2 (GIRK1/2) channel activator (IC50 values are 160, 887 and 914 nM for GIRK1/2, GIRK1/4 and GIRK1/3 respectively).</p>
    Formula:C17H14F2N4O
    Purity:97.85%
    Color and Shape:Solid
    Molecular weight:328.32