NS309
CAS: 18711-16-5
Ref. TM-T4612
| 5mg | 56.00 € | ||
| 10mg | 68.00 € | ||
| 25mg | 118.00 € | ||
| 50mg | 212.00 € | ||
| 100mg | 317.00 € | ||
| 200mg | 460.00 € | ||
| 500mg | 734.00 € | ||
| 1ml*10 (DMSO) | 62.00 € |
Product Information
- NS-309
- 1H-Indole-2,3-dione, 6,7-dichloro-, 3-oxime
- 6,7-Dichloro-1H-indole-2,3-dione 3-oxime
- 6,7-Dichloroisatin 3-oxime
- Indole-2,3-dione, 6,7-dichloro-, 3-oxime
- Ns 309
- Ns309
NS309 is a nonselective activator of small- and intermediate-conductance Ca2+-activated K+ (SK/KCa2 and IK/KCa3.1) channels (EC50s range from 0.12-1.2 μM for SK channels and 10-90 nM for IK channels). It can also activate voltage-gated Kv11.1 channels (hERG; IC50 = 1 μM), but does not, however, affect large conductance (BK/KCa1.1) channels. NS309 can modulate neuronal firing patterns by enhancing SK-mediated hyperpolarizing effects. It is 730-fold (SK channels) and 7,400-fold (IK channels) more potent than 1-EBIO and often used in conjunction with CyPPA to distinguish between SK1 and SK3 subtypes.
Chemical properties
Technical inquiry about: TM-T4612 NS309
If you want to request a quotation or place an order, please instead add the desired products to your cart and then request a quotation or order from the cart. It is faster, cheaper, and you will be able to benefit from the available discounts and other advantages.
