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Potassium Channel

Potassium Channel

Potassium channels are a diverse group of membrane proteins that facilitate the flow of potassium ions (K+) across the cell membrane. These channels play a crucial role in maintaining the resting membrane potential, regulating cell volume, and controlling the excitability of neurons and muscle cells. Potassium channels are involved in various physiological processes, including cardiac rhythm regulation, insulin secretion, and neurotransmitter release. Dysregulation of potassium channels is linked to conditions such as arrhythmias, epilepsy, and hypertension. At CymitQuimica, we offer a wide range of potassium channel modulators to support your research in electrophysiology, cardiovascular health, and neurobiology.

Found 276 products of "Potassium Channel"

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  • 11-deoxy-PGF2a
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    11-deoxy-PGF2a

    CAS:
    <p>11-deoxy-PGF2a is a thromboxane A2 receptor agonist that partially alleviates crowding in Lpar3(−/−) female embryos and induces smooth muscle contraction</p>
    Formula:C20H34O4
    Color and Shape:Solid
    Molecular weight:338.48

    Ref: TM-T26376

  • Glibornuride
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    Glibornuride

    CAS:
    <p>Glibornuride is a blocker of ATP-sensitive K+ channel(pKi: 5.75).</p>
    Formula:C18H26N2O4S
    Purity:99.5%
    Color and Shape:Solid
    Molecular weight:366.48

    Ref: TM-T15385

  • Sigma-1 receptor antagonist 3
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    Sigma-1 receptor antagonist 3

    CAS:
    <p>Sigma-1 receptor antagonist 3 is a more potent and selective antagonist of Sigma-1 (σ1) receptor (Ki = 1.14 nM) than σ2 receptor(Ki = 1239 nM).</p>
    Formula:C19H23ClFN3O
    Purity:99.95%
    Color and Shape:Solid
    Molecular weight:363.86

    Ref: TM-T12912

  • CLP257
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    CLP257

    CAS:
    <p>CLP257 is a selective K+-Cl− cotransporter KCC2 activator (EC50: 616 nM) and it is inactive against NKCC1, GABAA receptors, KCC1, KCC3 or KCC4.</p>
    Formula:C14H14FN3O2S
    Purity:99.5%
    Color and Shape:Solid
    Molecular weight:307.34

    Ref: TM-T14984

  • MCHR1 antagonist 2
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    MCHR1 antagonist 2

    CAS:
    <p>MCHR1 antagonist 2 is an antagonist of melanin-concentratin hormone receptor 1(MCH1-R, IC50 = 65 nM) and also inhibits hERG.</p>
    Formula:C23H21FN2O5
    Purity:98.29%
    Color and Shape:Solid
    Molecular weight:424.42

    Ref: TM-T11966

  • P-1075
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    P-1075

    CAS:
    <p>P-1075 activates SUR2-KIR6 channels at 45 nM; may open mitoKATP channels and protect the heart.</p>
    Formula:C12H17N5
    Purity:99.85%
    Color and Shape:Solid
    Molecular weight:231.3

    Ref: TM-T16420

  • C 101248
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    C 101248

    CAS:
    <p>C 101248 (KCNK13-IN-1) is a selective and potent tandem pore halogen inhibitor of K+ channel 1 (THIK-1) inhibitor and a human and mouse KCNK13 inhibitor.</p>
    Formula:C15H12N6O
    Purity:99.14% - 99.31%
    Color and Shape:Solid
    Molecular weight:292.3

    Ref: TM-T83962

  • Kv3 modulator 1
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    Kv3 modulator 1

    CAS:
    <p>Kv3 modulator 1 is a voltage-gated potassium channel Kv3 modulator that can be used to study neurologic-level diseases.</p>
    Formula:C20H20N4O4
    Purity:99.41%
    Color and Shape:Solid
    Molecular weight:380.4

    Ref: TM-T11787

  • Kv7.2/Kv7.3 agonist 1
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    Kv7.2/Kv7.3 agonist 1

    CAS:
    <p>Kv7.2/Kv7.3 agonist 1 (Compound 16) is an orally effective agonist for the KV7.2/7.3 channels (KV7.2/7.3 channel/KCNQ2/3) with an EC50 of 1.03 μM. This compound demonstrates analgesic effects in mouse models of chronic constriction injury (CCI) and Streptozotocin-induced diabetic peripheral neuropathy (DPNP), with ED50 values of 12.02 mg/kg and 9.63 mg/kg, respectively.</p>
    Formula:C14H14FN3O2
    Color and Shape:Solid
    Molecular weight:275.28

    Ref: TM-T201063

  • KCC2 Modulator-2
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    KCC2 Modulator-2

    CAS:
    <p>KCC2 Modulator-2 (example 53) is a regulator of KCC2 with an EC50 of 0.215 μM. It is used in the research of neurological diseases.</p>
    Formula:C35H45N5O3
    Color and Shape:Solid
    Molecular weight:583.76

    Ref: TM-T201666

  • KV1.3-IN-2
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    KV1.3-IN-2

    CAS:
    <p>KV1.3-IN-2 (Compound I) selectively inhibits the kv1.3 potassium channel without affecting the hERG channel. It is applicable in research related to immune-associated diseases such as psoriasis, rheumatoid arthritis, and systemic lupus erythematosus.</p>
    Formula:C16H23ClN2O4
    Color and Shape:Solid
    Molecular weight:342.818

    Ref: TM-T205655

  • cis-KV1.3-IN-1
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    cis-KV1.3-IN-1

    CAS:
    <p>cis-KV1.3-IN-1, also known as Compound cis-18, is the cis-isomer of KV1.3-IN-1 and functions as an inhibitor of the KV1.3 channel. In Xenopus laevis oocytes expressing human hKV1.3, cis-KV1.3-IN-1 (10 μM) achieves an inhibition rate of 25.53% against KV1.3.</p>
    Formula:C23H30N2O4S
    Color and Shape:Solid
    Molecular weight:430.56

    Ref: TM-T201783

  • Kv7.2/Kv7.3 modulator-1
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    Kv7.2/Kv7.3 modulator-1

    CAS:
    <p>Kv7.2/Kv7.3 modulator-1 (compound 6a) acts as a modulator for Kv7.2/Kv7.3 channels, with a pEC50 value of 7.96 for opening these channels. Kv7.2/Kv7.3 modulator-1 is applicable in research related to epilepsy, depression, brain injury, and pain.</p>
    Formula:C20H21F4N3O3
    Color and Shape:Solid
    Molecular weight:427.393

    Ref: TM-T206950

  • Opakalim
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    Opakalim

    CAS:
    <p>Opakalim is an activator of potassium channels (potassium channel) and exhibits anticonvulsant activity.</p>
    Formula:C18H22F2N4O
    Color and Shape:Solid
    Molecular weight:348.39

    Ref: TM-T206117

  • Kv7.2/Kv7.3 activator-1
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    Kv7.2/Kv7.3 activator-1

    CAS:
    <p>Kv7.2/Kv7.3 Activator-1 (compound 517) serves as a powerful activator of the Kv7.2/Kv7.3 channels, exhibiting an EC50 value of less than 1 µM. It holds potential for use in neurological disease research.</p>
    Formula:C19H22F2N4O
    Color and Shape:Solid
    Molecular weight:360.40

    Ref: TM-T89880

  • Indapamide
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    Indapamide

    CAS:
    <p>Indapamide (Noranat) is a non-thiazide sulphonamide diuretic compound, generally used in the treatment of hypertension, as well as decompensated cardiac failure.</p>
    Formula:C16H16ClN3O3S
    Purity:98.97% - 99.83%
    Color and Shape:Solid
    Molecular weight:365.83

    Ref: TM-T1498

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