Potassium Channel
Potassium channels are a diverse group of membrane proteins that facilitate the flow of potassium ions (K+) across the cell membrane. These channels play a crucial role in maintaining the resting membrane potential, regulating cell volume, and controlling the excitability of neurons and muscle cells. Potassium channels are involved in various physiological processes, including cardiac rhythm regulation, insulin secretion, and neurotransmitter release. Dysregulation of potassium channels is linked to conditions such as arrhythmias, epilepsy, and hypertension. At CymitQuimica, we offer a wide range of potassium channel modulators to support your research in electrophysiology, cardiovascular health, and neurobiology.
Found 323 products for "Potassium Channel".
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CM-TPMF
CAS:CM-TPMF is a highly efficient and potent activator of the K(Ca)2.1 channel, Ser293 in the transmembrane segment 5, neurological disorders.Formula:C16H17ClN6O2Purity:99.94%Color and Shape:SolidMolecular weight:360.8B-TPMF
CAS:B-TPMF is a highly efficient and selective KCa2.1 channel inhibitor with an IC50 of 31 nM, interacting with serine residue at position 293 to inhibit KCa2.1.Formula:C19H24N6O2Purity:99.82%Color and Shape:SolidMolecular weight:368.43TWIK-1/TREK-1-IN-2
CAS:TWIK-1/TREK-1-IN-2 (Compound 2g) serves as an inhibitor of both TWIK-1 and TREK-1, targeting the TREK-1 homodimer and TWIK-1/TREK-1 heterodimer with IC50 valuesFormula:C20H29F3N2O2Purity:98%Color and Shape:SolidMolecular weight:386.45TWIK-1/TREK-1-IN-1
CAS:Compound 2a, identified as TWIK-1/TREK-1-IN-1, acts as an inhibitor of the TREK-1, a two-pore domain potassium channel (K2p) that forms TREK-1 homodimers andFormula:C21H24F3NO3Purity:98%Color and Shape:SolidMolecular weight:395.42SKA-111
CAS:SKA-111 activates KCa3.1 potassium channels, modulates membrane potential in endothelial cells, and dilates rat coronary arteries.Formula:C12H10N2SPurity:99.9%Color and Shape:SolidMolecular weight:214.29PD-118057
CAS:PD-118057, a potent hERG activator, may treat long QT syndrome and heart failure without hERG activity inhibition.Formula:C21H17Cl2NO2Purity:99.95% - 99.97%Color and Shape:SolidMolecular weight:386.27Ref: TM-T16444
1mg79.00€2mg102.00€5mg172.00€1mL*10mM (DMSO)182.00€10mg249.00€25mg439.00€50mg655.00€100mg982.00€200mg1,324.00€MK-0448
CAS:MK-0448 is a novel and selective blocker of the Kv1.5 (KCNA5) channel, a key channel involved in cardiac repolarization current I Kur.Formula:C24H21FN4O2SPurity:99.25% - 99.79%Color and Shape:SolidMolecular weight:448.51TASK-1-IN-1
CAS:TASK-1-IN-1: Potent, selective TASK-1 blocker (IC50: 148 nM), weaker on TASK-3 (IC50: 1750 nM), anticancer properties.Formula:C22H20N2O2Purity:99.99%Color and Shape:SolidMolecular weight:344.41ZTZ240
CAS:ZTZ240 is a KCNQ2 channel activator used in the study of epilepsy.Formula:C12H8ClFN2OPurity:99.83%Color and Shape:SolidMolecular weight:250.66UK 66914
CAS:UK 66914 is a K(+) channel blocker for the study of cardiac arrhythmias.Formula:C18H24N4O3SPurity:99.04%Color and Shape:White SolidMolecular weight:376.47CyPPA
CAS:CyPPA enhances SK channels, reducing firing rate and extending apamin-sensitive afterhyperpolarization.Formula:C16H23N5Purity:99.88%Color and Shape:White SolidMolecular weight:285.39XE991
CAS:XE991 is a Kv7 (KCNQ) channel blocker.XE 991 dihydrochloride inhibits Kv7.1 (KCNQ1) and M-current and can be used in the study of neurological disorders.Formula:C26H20N2OPurity:99.54%Color and Shape:SolidMolecular weight:376.45ZM 226600
CAS:ZM 226600 is an ATP-sensitive potassium channel opener with an EC50 value of 500 nM. ZM226600 has an inhibitory effect on spontaneous bladder activity.Formula:C16H14F3NO4SPurity:99.87%Color and Shape:White SolidMolecular weight:373.35Ref: TM-T23563
2mg34.00€5mg52.00€1mL*10mM (DMSO)52.00€10mg75.00€25mg138.00€50mg215.00€100mg318.00€200mg444.00€RL648_81
CAS:RL648_81 is a selective activator of KCNQ2/3 channels (EC50 = 190 nM). RL648_81 can be used in studies about neuronal hyperexcitability neurologic disorders.Formula:C17H17F4N3O2Purity:99.82%Color and Shape:SolidMolecular weight:371.33DMP-543
CAS:DMP-543 (XR-543) is a potassium channel (KV7 channel) blocker that enhances the release of neurotransmitters.Formula:C26H18F2N2OPurity:99.74%Color and Shape:Yellow SolidMolecular weight:412.43GW 542573X
CAS:GW 542573X is a potent and selective small molecule Ca2+-activated K+ 2 (SK2) channel activator.GW 542573X induces a leftward shift in the Ca2+ response curveFormula:C19H28N2O5Purity:99.99%Color and Shape:White SolidMolecular weight:364.44TWIK-1/TREK-1-IN-3
CAS:TWIK-1/TREK-1-IN-3 is a potassium channel TREK-1 inhibitor TWIK-1/TREK-1-IN-3 has antidepressant activity and can be used to study depression.Formula:C19H27F3N2O2Purity:99.04%Color and Shape:SolidMolecular weight:372.43(+)-KCC2 blocker 1
CAS:(+)-KCC2 blocker 1 is a selective blocker of KCC2 (IC50 = 0.4 μM).Formula:C22H25NO5SPurity:99.88%Color and Shape:SolidMolecular weight:415.5Ref: TM-T12504
1mg94.00€5mg200.00€1mL*10mM (DMSO)227.00€10mg294.00€25mg522.00€50mg747.00€100mg1,035.00€500mg2,052.00€IKs124
CAS:IKs124 is a KCNE2/KCNQ1 potassium channel blocker, for hKCNE1 and hKCNE3, and can be used to study peptic ulcers.Formula:C18H26N2O3SPurity:99.53%Color and Shape:SolidMolecular weight:350.48Linaprazan
CAS:Linaprazan (AZD0865) inhibits gastric H+,K+-ATPase by K+-competitive binding with an IC50 of 1.0 μM.Formula:C21H26N4O2Purity:99.54%Color and Shape:White SolidMolecular weight:366.46
