Potassium Channel
Potassium channels are a diverse group of membrane proteins that facilitate the flow of potassium ions (K+) across the cell membrane. These channels play a crucial role in maintaining the resting membrane potential, regulating cell volume, and controlling the excitability of neurons and muscle cells. Potassium channels are involved in various physiological processes, including cardiac rhythm regulation, insulin secretion, and neurotransmitter release. Dysregulation of potassium channels is linked to conditions such as arrhythmias, epilepsy, and hypertension. At CymitQuimica, we offer a wide range of potassium channel modulators to support your research in electrophysiology, cardiovascular health, and neurobiology.
Found 323 products for "Potassium Channel".
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Mefloquine hydrochloride
CAS:Mefloquine hydrochloride (Mefloquin hydrochloride) is a quinoline derivative used for the prevention and therapy of P. falciparum malaria.Formula:C17H17ClF6N2OPurity:99% - 99.99%Color and Shape:SolidMolecular weight:414.77Minoxidil
CAS:Minoxidil (U10858) is an orally administered vasodilator with hair growth stimulatory and antihypertensive effects.Formula:C9H15N5OPurity:99.88% - >99.99%Color and Shape:Crystals From Methanol-Acetonitrile SolidMolecular weight:209.25Dronedarone hydrochloride
CAS:Dronedarone hydrochloride (SR33589) is an amiodarone analog which has an effective and promising treatment for Atrial fibrillation.Formula:C31H44N2O5S·HClPurity:99.61%Color and Shape:White SolidMolecular weight:593.22Ref: TM-T1073
5mg35.00€1mL*10mM (DMSO)49.00€10mg50.00€25mg82.00€50mg111.00€100mg166.00€200mg236.00€500mg403.00€Tipepidine hydrochloride
CAS:Tipepidine hydrochloride: reversible DA D2 receptor inhibitor, IC50 7.0 μM, with antidepressant effects.Formula:C15H18ClNS2Purity:99.97%Color and Shape:White SolidMolecular weight:311.89Terfenadine
CAS:Terfenadine, metabolized to fexofenadine by CYP3A4, is a non-sedative antihistamine targeting H1 receptors.Formula:C32H41NO2Purity:98.76% - 99.97%Color and Shape:SolidMolecular weight:471.67AZD 7009
CAS:AZD 7009 is a novel antiarrhythmic compound that inhibits the sodium current of hNav1.5 in CHO K1 cells with an IC50 of 11 uM.Formula:C23H34N4O5Purity:98.42% - 98.51%Color and Shape:White OilMolecular weight:446.54Foslevcromakalim
CAS:Foslevcromakalim (QLS-101) is an KATP opener, converted to its active form by alkaline phosphatase in vivo, reduces intraocular pressure in normotensive mice.Formula:C16H19N2O6PPurity:99.73%Color and Shape:White SolidMolecular weight:366.31VU6080824 HCl
VU6080824 HCl is an inhibitor of the inward-rectifier potassium channel Kir2.1 (IC₅₀ = 0.35 μM), exhibiting excellent target efficacy and pharmacokinetics.Formula:C22H23NO2Purity:99.87%Color and Shape:White SolidMolecular weight:333.42κM-Conotoxin RIIIK
CAS:κM-Conotoxin RIIIK is a potassium channel antagonist that inhibits voltage-activated potassium ion channels [1].Formula:C106H178N34O33S6Purity:98%Color and Shape:SolidMolecular weight:2649.15Tertiapin
CAS:Tertiapin (reduced) is a synthetic bee venom peptide characterized by disulfide bonds between Cys3-Cys14 and Cys5-Cys18. It acts as an inhibitor of inward-rectifying potassium channels (potassium Channel) and can also block the activity of calcium-activated large conductance potassium channels. Tertiapin (reduced) is utilized in research related to diseases such as rheumatoid arthritis and multiple sclerosis.Formula:C106H180N34O23S5Color and Shape:SolidMolecular weight:2459.1Ebio2
Ebio2 is an effective activator of KCNQ2.Formula:C17H19F2N3O2Color and Shape:SolidMolecular weight:335.349Allatostatin II
CAS:Allatostatin II is an Inhibitors of juvenile hormone synthesis in insects.Formula:C49H74N14O13Purity:98%Color and Shape:SolidMolecular weight:1067.2Phe-Met-Arg-Phe, amide
CAS:Phe-Met-Arg-Phe amide activates K+ current in neurons (ED50=23 nM), co-localizes with neuropeptide Y in brain regions.Formula:C29H42N8O4SPurity:98%Color and Shape:SolidMolecular weight:598.76ShK-Dap22
CAS:Potent KV1.3 channel blocker; Kd 23 pM; selective; inhibits T cell activation; IC50 < 500 pM for mKV1.3.Formula:C166H268N54O48S7Purity:98%Color and Shape:SolidMolecular weight:4012.7MASP-2-IN-1
MASP-2-IN-1 (Compound 77) is an inhibitor of mannan-binding lectin-associated serine proteases (MASP), specifically targeting MASP2 and MASP3, with IC50 values of 11.4 nM and 13.2 µM, respectively. It shows weak inhibitory activity on hERG with an IC50 of 175 µM. This compound exhibits poor stability in mouse plasma, with a half-life of 4.4 hours.Formula:C22H21N7O3SColor and Shape:SolidMolecular weight:463.512GsAF-I
GsAF-I is a potent blocker of Na_v and hERG1 channels, exhibiting half-maximal inhibitory concentrations (IC50s) of 0.36 μM (Na_v 1.1), 0.6 μM (Na_v 1.2), 1.28Formula:C160H244N46O42S7Purity:98%Color and Shape:SolidMolecular weight:3708.39Pinacidil monohydrate
CAS:Pinacidil monohydrate is a potassium channel activator, antihypertensive drug.Formula:C13H21N5OPurity:99.94% - 99.98%Color and Shape:SolidMolecular weight:263.34Jingzhaotoxin-XII
Jingzhaotoxin-XII (JzTx-XII) functions as a potent inhibitor of the Kv4.1 channel, exhibiting an inhibitory concentration (IC50) of 0.363 μM.Formula:C161H227N41O44S7Purity:98%Color and Shape:SolidMolecular weight:3665.23Dalazatide HCl
Dalazatide HCl is a peptide and specific Kv1.3 inhibitor that suppresses the activation and proliferation of memory effector T cells,Color and Shape:SolidMolecular weight:4317.53 (Free base)Lei-Dab7 TFA
Lei-Dab7 TFA blocks SK2 channels with 3.8 nM affinity, is >200x selective, and enhances LTP in rat hippocampus.Formula:C143H237F3N46O41S6Color and Shape:SolidMolecular weight:3506.08
