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Proton pump

Proton pump

Proton pumps are membrane proteins that actively transport protons (H+) across the cell membrane or organelle membranes, creating a proton gradient that is essential for various cellular processes. The most well-known proton pump is the H+/K+ ATPase, found in the stomach lining, which is responsible for acid secretion. Proton pumps are also critical in cellular respiration and pH regulation. Dysregulation of proton pump activity is associated with conditions such as acid reflux, ulcers, and metabolic acidosis. At CymitQuimica, we provide a selection of proton pump inhibitors and modulators to support your research in gastroenterology, metabolism, and cellular bioenergetics.

Found 42 products of "Proton pump"

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  • V-ATPase-IN-1
    Targetmol
    + Info

    V-ATPase-IN-1

    CAS:
    <p>V-ATPase-IN-1 (Compound 3b-03) is an inhibitor of Vacuolar-type H+-ATPases (V-ATPase), exhibiting an inhibition constant (IC50) of 194.80 μM and effectively targeting the V-ATPase subunit A with a dissociation constant (Kd) of 0.803 μM. This compound demonstrates insecticidal activity against M. separata (LC50 = 2.64 mM), aiding in the development of chemical insecticides.</p>
    Formula:C21H20ClNO2
    Color and Shape:Solid
    Molecular weight:353.84

    Ref: TM-T200467

  • Zastaprazan
    Targetmol
    + Info

    Zastaprazan

    CAS:
    Zastaprazan (JP-1366, compound 6) is a potassium-competitive acid blocker and proton pump inhibitor that suppresses gastric acid secretion, indicated for GERD.
    Formula:C22H26N4O
    Purity:99.97%
    Color and Shape:Solid
    Molecular weight:362.48

    Ref: TM-T39583

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    Discontinued
    Discontinued product