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Proton pump

Proton pump

Proton pumps are membrane proteins that actively transport protons (H+) across the cell membrane or organelle membranes, creating a proton gradient that is essential for various cellular processes. The most well-known proton pump is the H+/K+ ATPase, found in the stomach lining, which is responsible for acid secretion. Proton pumps are also critical in cellular respiration and pH regulation. Dysregulation of proton pump activity is associated with conditions such as acid reflux, ulcers, and metabolic acidosis. At CymitQuimica, we provide a selection of proton pump inhibitors and modulators to support your research in gastroenterology, metabolism, and cellular bioenergetics.

Found 39 products of "Proton pump"

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  • Pantoprazole sodium
    Targetmol
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    Pantoprazole sodium

    CAS:
    <p>Pantoprazole sodium is a proton pump inhibitor that irreversibly blocks gastric acid secretion by bonding with H+/K+-ATPase.</p>
    Formula:C16H14F2N3NaO4S
    Purity:96.92% - 99.81%
    Color and Shape:White To Off-White Solid
    Molecular weight:405.35

    Ref: TM-T6929

  • Ilaprazole
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    Ilaprazole

    CAS:
    <p>Ilaprazole (IY-81149) is a proton pump inhibitor used in the treatment of dyspepsia gastroesophageal reflux disease (GORD/GERD) and duodenal ulcer.</p>
    Formula:C19H18N4O2S
    Purity:99.91%
    Color and Shape:Solid
    Molecular weight:366.44

    Ref: TM-T1756L

  • Rabeprazole sodium
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    Rabeprazole sodium

    CAS:
    <p>Rabeprazole sodium treats stomach ulcers and Zollinger-Ellison syndrome, blocking ATPase in gastric cells.</p>
    Formula:C18H20N3NaO3S
    Purity:98% - 99.912%
    Color and Shape:White Or Off White Crystalline Powder
    Molecular weight:381.42

    Ref: TM-T1651

  • Bafilomycin A1
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    Bafilomycin A1

    CAS:
    <p>Bafilomycin A1 belongs to the macrolide class of antibiotics and is a V-ATPase (IC50=0.44 nM) that is specific and reversible.</p>
    Formula:C35H58O9
    Purity:95.87% - 99.36%
    Color and Shape:Solid
    Molecular weight:622.83

    Ref: TM-T6740

  • Vonoprazan Fumarate
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    Vonoprazan Fumarate

    CAS:
    <p>Vonoprazan Fumarate (TAK438) , a novel potassium-competitive acid blocker, inhibits gastric acid secretion.</p>
    Formula:C21H20FN3O6S
    Purity:98.94%
    Color and Shape:Solid
    Molecular weight:461.46

    Ref: TM-T21254

  • Pantoprazole
    Targetmol
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    Pantoprazole

    CAS:
    <p>Pantoprazole (BY1023) is a proton pump inhibitor used for short-term treatment of erosion and ulceration of the esophagus caused by gastroesophageal reflux</p>
    Formula:C16H15F2N3O4S
    Purity:99.28% - 99.63%
    Color and Shape:Almost White Solid
    Molecular weight:383.37

    Ref: TM-T6928

  • KM 91104
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    KM 91104

    CAS:
    <p>KM 91104 is a cell permeable inhibitor of V-ATPase. KM91104 specifically targets the interaction between V-ATPase subunit A3 and subunit B2.</p>
    Formula:C14H12N2O4
    Purity:99.04%
    Color and Shape:Solid
    Molecular weight:272.26

    Ref: TM-T9230

  • Diphyllin
    Targetmol
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    Diphyllin

    CAS:
    <p>Diphyllin could be characterized as a new V-ATPase inhibitor in treating gastric cancer and inhibiting the phosphorylation of LRP6 in Wnt/β-catenin signaling.</p>
    Formula:C21H16O7
    Purity:99.76% - 99.98%
    Color and Shape:Solid
    Molecular weight:380.35

    Ref: TM-TN1103

  • ATP4A Protein, Human, Recombinant (His & Myc)
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    ATP4A Protein, Human, Recombinant (His & Myc)

    <p>ATP4A Protein, Human, Recombinant (His &amp; Myc) is expressed in E.</p>
    Color and Shape:Lyophilized Powder
    Molecular weight:54.6 kDa (predicted)

    Ref: TM-TMPH-01892

  • Omeprazole Sodium
    Targetmol
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    Omeprazole Sodium

    CAS:
    <p>Omeprazole Sodium is a proton pump inhibitor(PPI) and suppresses gastric acid secretion.</p>
    Formula:C17H18N3NaO3S
    Purity:99.84%
    Color and Shape:Clear In Water
    Molecular weight:367.4

    Ref: TM-T22391

  • WY-47766
    Targetmol
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    WY-47766

    CAS:
    <p>WY-47766, a proton pump inhibitor, is used potentially for the treatment of postmenopausal osteoporosis.</p>
    Formula:C14H13N3O2S
    Purity:97.63% - 99.83%
    Color and Shape:Solid
    Molecular weight:287.34

    Ref: TM-T29164

  • Saviprazole
    Targetmol
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    Saviprazole

    CAS:
    <p>Saviprazole (Hoe-731), a proton pump inhibitor, is used potentially for treatment of gastric ulcer.</p>
    Formula:C15H10F7N3O2S2
    Purity:97.07% - 97.17%
    Color and Shape:Solid
    Molecular weight:461.38

    Ref: TM-T28665

  • Abeprazan hydrochloride
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    Abeprazan hydrochloride

    CAS:
    <p>Abeprazan hydrochloride (Fexuprazan hydrochloride) is an effective reversible potassium-competitive acid blocker with oral activity, inhibiting H+, K+ -atPase</p>
    Formula:C19H18ClF3N2O3S
    Purity:98.57%
    Color and Shape:Solid
    Molecular weight:446.87

    Ref: TM-T10221

  • Ilaprazole sodium hydrate
    Targetmol
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    Ilaprazole sodium hydrate

    CAS:
    <p>Ilaprazole sodium hydrate (IY-81149 sodium hydrate) is a proton pump inhibitor that blocks the transport of HSV particles.</p>
    Formula:C19H21N4NaO4S
    Purity:99.2%
    Color and Shape:Solid
    Molecular weight:424.45

    Ref: TM-T78218

  • Linaprazan
    Targetmol
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    Linaprazan

    CAS:
    <p>Linaprazan (AZD0865) inhibits gastric H+,K+-ATPase by K+-competitive binding with an IC50 of 1.0 μM.</p>
    Formula:C21H26N4O2
    Purity:99.54%
    Color and Shape:Solid
    Molecular weight:366.46

    Ref: TM-T10435

  • Pumaprazole
    Targetmol
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    Pumaprazole

    CAS:
    <p>Pumaprazole (BY-841) is an antagonist of a reversible proton pump.</p>
    Formula:C19H22N4O2
    Purity:99.91%
    Color and Shape:Solid
    Molecular weight:338.4

    Ref: TM-T16682

  • Soraprazan
    Targetmol
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    Soraprazan

    CAS:
    <p>BS3 Crosslinker (Bis(sulfosuccinimidyl)suberate) is an ADC linker that can be used to synthesize antibody-coupled active molecules.</p>
    Formula:C21H25N3O3
    Purity:97.69% - 99.84%
    Color and Shape:Solid
    Molecular weight:367.44

    Ref: TM-T12977

  • V-ATPase-IN-1
    Targetmol
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    V-ATPase-IN-1

    CAS:
    <p>V-ATPase-IN-1 (Compound 3b-03) is an inhibitor of Vacuolar-type H+-ATPases (V-ATPase), exhibiting an inhibition constant (IC50) of 194.80 μM and effectively targeting the V-ATPase subunit A with a dissociation constant (Kd) of 0.803 μM. This compound demonstrates insecticidal activity against M. separata (LC50 = 2.64 mM), aiding in the development of chemical insecticides.</p>
    Formula:C21H20ClNO2
    Color and Shape:Solid
    Molecular weight:353.84

    Ref: TM-T200467

  • Zastaprazan
    Targetmol
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    Zastaprazan

    CAS:
    <p>Zastaprazan (JP-1366, compound 6) is a potassium-competitive acid blocker and proton pump inhibitor that suppresses gastric acid secretion, indicated for GERD.</p>
    Formula:C22H26N4O
    Purity:99.97%
    Color and Shape:Solid
    Molecular weight:362.48

    Ref: TM-T39583

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    Discontinued
    Discontinued product