Chloride channel
Chloride channels are membrane proteins that control the movement of chloride ions across cellular membranes, playing a vital role in maintaining cell volume, electrical excitability, and acid-base balance. Dysregulation of chloride channels is linked to diseases such as cystic fibrosis, epilepsy, and kidney disorders. At CymitQuimica, we offer a variety of chloride channel modulators to support your research in ion transport, cellular homeostasis, and disease mechanisms.
Found 54 products of "Chloride channel"
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ANO1-IN-2
CAS:ANO1-IN-2: potent ANO1 blocker (IC50: 1.75 μM), less effective on ANO2 (IC50: 7.43 μM), inhibits glioblastoma cell growth.Formula:C16H14ClN3O2S2Color and Shape:SolidMolecular weight:379.88ANO1-IN-1
CAS:ANO1-IN-1 blocks ANO1/2 channels (IC50: 2.56/15.43 μM) and hinders glioma cell growth.Formula:C18H28N2O2SPurity:99.93%Color and Shape:SolidMolecular weight:336.49Ani9
CAS:Ani9 selectively blocks ANO1/TMEM16A with a 77 nM IC50, useful for ANO1 research and treating cancer, hypertension, pain, diarrhea, asthma.
Formula:C17H17ClN2O3Purity:99.73%Color and Shape:SolidMolecular weight:332.78Stepronin
CAS:Stepronin (TTPG) shows expectorant activities and inhibits airway secretion.Formula:C10H11NO4S2Purity:99.59%Color and Shape:White Or Off White CrystallineMolecular weight:273.33Ref: TM-T21433
5mg48.00€1mL*10mM (DMSO)48.00€10mg71.00€25mg111.00€50mg187.00€100mg290.00€200mg410.00€Losigamone
CAS:Losigamone (AO-33) is an agonist of GABA receptor and can be used in studies about the treatment of partial seizures.Formula:C12H11ClO4Purity:99.98%Color and Shape:SolidMolecular weight:254.67R(+)-IAA-94
CAS:R(+)-IAA-94 (Methylindazone) blocks epithelial chloride channels; inhibits Nef-sdAb19 binding.Formula:C17H18Cl2O4Purity:98.95% - 99.17%Color and Shape:SolidMolecular weight:357.23PAT1inh-B01
CAS:PAT1inh-B01, a selective SLC26A6 inhibitor, impedes PAT1 (a Cl-/HCO3- exchanger) activity, with an IC50 of 350 nM, effectively inhibiting anion exchange.Formula:C22H18BrF3N6O2Color and Shape:SolidMolecular weight:535.32ARN 11391
CAS:ARN 11391 enhances the function of the IP3-gated calcium channel ITPR1 (Inositol 1,4,5-trisphosphate (IP3) receptor type 1), boosting intracellular calcium ionFormula:C22H29N3O3Color and Shape:SolidMolecular weight:383.49DIOA
CAS:DIOA acts as a potent antagonist of acid-sensitive outwardly rectifying (ASOR) anion channels [1].Formula:C20H24Cl2O4Color and Shape:SolidMolecular weight:399.31OADS
CAS:OADS is an inhibitor of ClC-ec1 with low micromolar affinity. OADS has no specific effect on a CLC channel (ClC-1).Formula:C30H42N2O8S2Color and Shape:SolidMolecular weight:622.79DFBTA
DFBTA inhibits ANO1 with IC50 of 24 nM, effectively treating inflammatory pain orally.Formula:C18H10ClF2NO3SColor and Shape:SolidMolecular weight:393.79S9-A13
CAS:S9-A13 is a potent and selective inhibitor of SLC26A9, exhibiting an IC50 of 90.9 nM without inhibiting other members of the SLC26 family, such as SLC26A3, SLC26A4, and SLC26A6. It also inhibits the SLC26A9 Cl- current in cells lacking CFTR expression.Formula:C20H18ClN3O2SColor and Shape:SolidMolecular weight:399.89NMD670
CAS:NMD670 is an orally active, partial inhibitor of the skeletal muscle-specific chloride channel ClC-1. It enhances muscle excitability and neuromuscular transmission, restoring muscle function and mobility. NMD670 has a favorable safety profile and improves muscle function in rats, particularly in an MG rat model [1].Formula:C12H10BrNO4Color and Shape:SolidMolecular weight:312.12T16A(inh)-C01
CAS:T16A(inh)-C01 is the Ca(2+)-activated Cl(-) Channel, Ano1 class C inhibitor.Formula:C18H16O5Purity:98%Color and Shape:SolidMolecular weight:312.32
