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Chloride channel

Chloride channel

Chloride channels are membrane proteins that control the movement of chloride ions across cellular membranes, playing a vital role in maintaining cell volume, electrical excitability, and acid-base balance. Dysregulation of chloride channels is linked to diseases such as cystic fibrosis, epilepsy, and kidney disorders. At CymitQuimica, we offer a variety of chloride channel modulators to support your research in ion transport, cellular homeostasis, and disease mechanisms.

Found 49 products of "Chloride channel"

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  • Stepronin
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    Stepronin

    CAS:
    <p>Stepronin (TTPG) shows expectorant activities and inhibits airway secretion.</p>
    Formula:C10H11NO4S2
    Purity:99.59%
    Color and Shape:White Or Off White Crystalline
    Molecular weight:273.33

    Ref: TM-T21433

  • ANO1-IN-1
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    ANO1-IN-1

    CAS:
    <p>ANO1-IN-1 blocks ANO1/2 channels (IC50: 2.56/15.43 μM) and hinders glioma cell growth.</p>
    Formula:C18H28N2O2S
    Purity:99.66%
    Color and Shape:Solid
    Molecular weight:336.49

    Ref: TM-T61051

  • Ani9
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    Ani9

    CAS:
    <p>Ani9 selectively blocks ANO1/TMEM16A with a 77 nM IC50, useful for ANO1 research and treating cancer, hypertension, pain, diarrhea, asthma.</p>
    Formula:C17H17ClN2O3
    Purity:99.73%
    Color and Shape:Solid
    Molecular weight:332.78

    Ref: TM-T26630

  • ARN 11391
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    ARN 11391

    CAS:
    <p>ARN 11391 enhances the function of the IP3-gated calcium channel ITPR1 (Inositol 1,4,5-trisphosphate (IP3) receptor type 1), boosting intracellular calcium ion</p>
    Formula:C22H29N3O3
    Color and Shape:Solid
    Molecular weight:383.49

    Ref: TM-T83950

  • OADS
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    OADS

    CAS:
    <p>OADS is an inhibitor of ClC-ec1 with low micromolar affinity. OADS has no specific effect on a CLC channel (ClC-1).</p>
    Formula:C30H42N2O8S2
    Color and Shape:Solid
    Molecular weight:622.79

    Ref: TM-T69036

  • S9-A13
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    S9-A13

    CAS:
    <p>S9-A13 is a potent and selective inhibitor of SLC26A9, exhibiting an IC50 of 90.9 nM without inhibiting other members of the SLC26 family, such as SLC26A3, SLC26A4, and SLC26A6. It also inhibits the SLC26A9 Cl- current in cells lacking CFTR expression.</p>
    Formula:C20H18ClN3O2S
    Color and Shape:Solid
    Molecular weight:399.89

    Ref: TM-T201301

  • NMD670
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    NMD670

    CAS:
    <p>NMD670 is an orally active, partial inhibitor of the skeletal muscle-specific chloride channel ClC-1. It enhances muscle excitability and neuromuscular transmission, restoring muscle function and mobility. NMD670 has a favorable safety profile and improves muscle function in rats, particularly in an MG rat model [1].</p>
    Formula:C12H10BrNO4
    Color and Shape:Solid
    Molecular weight:312.12

    Ref: TM-T87024

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    DFBTA

    <p>DFBTA inhibits ANO1 with IC50 of 24 nM, effectively treating inflammatory pain orally.</p>
    Formula:C18H10ClF2NO3S
    Color and Shape:Solid
    Molecular weight:393.79

    Ref: TM-T61818

  • T16A(inh)-C01
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    T16A(inh)-C01

    CAS:
    <p>T16A(inh)-C01 is the Ca(2+)-activated Cl(-) Channel, Ano1 class C inhibitor.</p>
    Formula:C18H16O5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:312.32

    Ref: TM-T24846

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