Chloride channel
Chloride channels are membrane proteins that control the movement of chloride ions across cellular membranes, playing a vital role in maintaining cell volume, electrical excitability, and acid-base balance. Dysregulation of chloride channels is linked to diseases such as cystic fibrosis, epilepsy, and kidney disorders. At CymitQuimica, we offer a variety of chloride channel modulators to support your research in ion transport, cellular homeostasis, and disease mechanisms.
Found 49 products of "Chloride channel"
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Adjudin
CAS:<p>Adjudin (AF-2364) is a small molecule compound known to possess antispermatogenic function, attenuates microglia activation by suppression of the NF-κB pathway.</p>Formula:C15H12Cl2N4OPurity:96.51% - ≥95%Color and Shape:SolidMolecular weight:335.19Anthracene-9-carboxylic acid
CAS:<p>Anthracene-9-carboxylic acid is an inhibitor of chloride transport with a moderate to strong inhibitory action on PKA activated cardiac IcI.</p>Formula:C15H10O2Purity:99.05%Color and Shape:Yellow Cystalline PowderMolecular weight:222.24Phenyl benzoate
CAS:<p>Phenyl benzoate is a benzoate ester obtained by the formal condensation of phenol with benzoic acid.It is an important organic synthesis intermediate.</p>Formula:C13H10O2Purity:99.63%Color and Shape:White Crystalline PowderMolecular weight:198.22Org 25543
CAS:<p>Org 25543 is the development of an N-Acyl amino acid that selectively inhibits the glycine transporter 2 to produce analgesia in a rat model of chronic pain.</p>Formula:C24H32N2O4Purity:99.13%Color and Shape:SolidMolecular weight:412.52CaCCinh-A01
CAS:<p>CaCCinh-A01 is an inhibitor of the calcium-activated chloride channel (CaCC, 10 μM) and TMEM16A (IC50: 2.1 μM).</p>Formula:C18H21NO4SPurity:99.36% - >99.99%Color and Shape:SolidMolecular weight:347.43Selamectin
CAS:<p>Selamectin (UK-124114) is a macrocyclic lactone derivative of ivermectin, an anthelmintic that potentiates glutamate- and GABA-gated chloride channel opening in</p>Formula:C43H63NO11Purity:99.84%Color and Shape:SolidMolecular weight:769.96Irisolidone
CAS:<p>Irisolidone is a potent volume-regulated anion channel (VRAC) current inhibitor, it exhibits high efficacy for VRAC blockade with IC50s of 5-13 μM.</p>Formula:C17H14O6Purity:99.41% - 99.87%Color and Shape:SolidMolecular weight:314.29Fenamic acid
CAS:<p>Fenamic acid (N-Phenylanthranilic acid) is a chloride channel blocker that causes renal papillary necrosis in rats.</p>Formula:C13H11NO2Purity:99.6%Color and Shape:White To Off-White Crystalline PowderMolecular weight:213.2319Lubiprostone
CAS:<p>Lubiprostone (RU-0211), an activator of ClC-2 chloride channels, is used in the therapy of idiopathic chronic constipation.</p>Formula:C20H32F2O5Purity:97.31% - 98.54%Color and Shape:White Odorless Crystals Or Crystalline PowderMolecular weight:390.46Talniflumate
CAS:<p>Talniflumate (Somalgen) is a calcium-activated chloride channel (hCLCA1/mCLCA3) blocker that reduces mucin synthesis and releases in animal models and cell</p>Formula:C21H13F3N2O4Purity:98% - 99.81%Color and Shape:White To Pale Yellow Crystalline PowderMolecular weight:414.33NS5818
CAS:<p>NS5818 inhibits ClC.</p>Formula:C23H19Cl2N7O2Purity:98%Color and Shape:SolidMolecular weight:496.35Alilusem
CAS:<p>Alilusem is a new diuretic that is beneficial to the clinical treatment of hypertension.</p>Formula:C17H15ClKN2O5SColor and Shape:SolidMolecular weight:433.92H100
CAS:<p>H100 inhibits Cl- transport, mildly affects NaK2Cl cotransporter and Band 3 anion exchanger, not KCl cotransporter.</p>Formula:C18H16N2O6SPurity:98%Color and Shape:SolidMolecular weight:388.4ANO1-IN-2
CAS:<p>ANO1-IN-2: potent ANO1 blocker (IC50: 1.75 μM), less effective on ANO2 (IC50: 7.43 μM), inhibits glioblastoma cell growth.</p>Formula:C16H14ClN3O2S2Color and Shape:SolidMolecular weight:379.88BTG-1640
CAS:<p>BTG-1640 is used potentially for the treatment of anxiety and panic disorder.</p>Formula:C15H19NO2Color and Shape:SolidMolecular weight:245.32Bts 39542
CAS:<p>Bts 39542 is a diuretic that plays a major role in the Henle circulation and increases renal blood flow without affecting glomerular filtration rate.</p>Formula:C16H11ClN4O3SColor and Shape:SolidMolecular weight:374.8IAA-94
CAS:<p>IAA-94 is an inhibitor of chloride channels, it binds channels in bovine kidney cortex microsomes with a Ki value of 1 µM.</p>Formula:C17H18Cl2O4Color and Shape:SolidMolecular weight:357.23Hydroflumethiazide
CAS:<p>Hydroflumethiazide is a thiazide diuretic. It has also shown the activity of anti-hypertensive.</p>Formula:C8H8F3N3O4S2Color and Shape:Crystals SolidMolecular weight:331.29Losigamone
CAS:<p>Losigamone (AO-33) is an agonist of GABA receptor and can be used in studies about the treatment of partial seizures.</p>Formula:C12H11ClO4Purity:99.98%Color and Shape:SolidMolecular weight:254.67R(+)-IAA-94
CAS:<p>R(+)-IAA-94 (Methylindazone) blocks epithelial chloride channels; inhibits Nef-sdAb19 binding.</p>Formula:C17H18Cl2O4Purity:98.95% - 99.17%Color and Shape:SolidMolecular weight:357.23
