Chloride channel
Chloride channels are membrane proteins that control the movement of chloride ions across cellular membranes, playing a vital role in maintaining cell volume, electrical excitability, and acid-base balance. Dysregulation of chloride channels is linked to diseases such as cystic fibrosis, epilepsy, and kidney disorders. At CymitQuimica, we offer a variety of chloride channel modulators to support your research in ion transport, cellular homeostasis, and disease mechanisms.
Found 54 products for "Chloride channel".
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CaCCinh-A01
CAS:CaCCinh-A01 is an inhibitor of the calcium-activated chloride channel (CaCC, 10 μM) and TMEM16A (IC50: 2.1 μM).Formula:C18H21NO4SPurity:99.36% - >99.99%Color and Shape:White SolidMolecular weight:347.43Adjudin
CAS:Adjudin (AF-2364) is a small molecule compound known to possess antispermatogenic function, attenuates microglia activation by suppression of the NF-κB pathway.Formula:C15H12Cl2N4OPurity:96.51% - ≥95%Color and Shape:SolidMolecular weight:335.19Selamectin
CAS:Selamectin (UK-124114) is a macrocyclic lactone derivative of ivermectin, an anthelmintic that potentiates glutamate- and GABA-gated chloride channel opening inFormula:C43H63NO11Purity:99.84%Color and Shape:Yellow SolidMolecular weight:769.96Irisolidone
CAS:Irisolidone is a potent volume-regulated anion channel (VRAC) current inhibitor, it exhibits high efficacy for VRAC blockade with IC50s of 5-13 μM.Formula:C17H14O6Purity:99.41% - 99.87%Color and Shape:SolidMolecular weight:314.29Ref: TM-TN1035
1mg105.00€5mg250.00€1mL*10mM (DMSO)255.00€10mg378.00€25mg618.00€50mg859.00€100mg1,153.00€Fenamic acid
CAS:Fenamic acid (N-Phenylanthranilic acid) is a chloride channel blocker that causes renal papillary necrosis in rats.Formula:C13H11NO2Purity:99.6%Color and Shape:SolidMolecular weight:213.2319Anthracene-9-carboxylic acid
CAS:Anthracene-9-carboxylic acid is an inhibitor of chloride transport with a moderate to strong inhibitory action on PKA activated cardiac IcI.Formula:C15H10O2Purity:99.05%Color and Shape:SolidMolecular weight:222.24Phenyl benzoate
CAS:Phenyl benzoate is a benzoate ester obtained by the formal condensation of phenol with benzoic acid.It is an important organic synthesis intermediate.Formula:C13H10O2Purity:99.63%Color and Shape:White SolidMolecular weight:198.22Lubiprostone
CAS:Lubiprostone (RU-0211), an activator of ClC-2 chloride channels, is used in the therapy of idiopathic chronic constipation.Formula:C20H32F2O5Purity:97.31% - 98.54%Color and Shape:SolidMolecular weight:390.46Talniflumate
CAS:Talniflumate (Somalgen) is a calcium-activated chloride channel (hCLCA1/mCLCA3) blocker that reduces mucin synthesis and releases in animal models and cellFormula:C21H13F3N2O4Purity:98% - 99.81%Color and Shape:Yellow SolidMolecular weight:414.33NPPB
CAS:NPPB is a chloride channel blocker with IC50 of 80 nM .Formula:C16H16N2O4Purity:99.95%Color and Shape:White SolidMolecular weight:300.31MONNA
CAS:MONNA is a potent TMEM16A (Anoctamin-1) blocker (IC50 : 80 nM). It induces vasorelaxation of rodent resistance arteries in presence or absence of chloride ions.Formula:C18H14N2O5Purity:98.29%Color and Shape:SolidMolecular weight:338.31Org 25543
CAS:Org 25543 is the development of an N-Acyl amino acid that selectively inhibits the glycine transporter 2 to produce analgesia in a rat model of chronic pain.Formula:C24H32N2O4Purity:99.31%Color and Shape:SolidMolecular weight:412.52ANO1-IN-2
CAS:ANO1-IN-2: potent ANO1 blocker (IC50: 1.75 μM), less effective on ANO2 (IC50: 7.43 μM), inhibits glioblastoma cell growth.Formula:C16H14ClN3O2S2Color and Shape:SolidMolecular weight:379.88Bts 39542
CAS:Bts 39542 is a diuretic that plays a major role in the Henle circulation and increases renal blood flow without affecting glomerular filtration rate.Formula:C16H11ClN4O3SColor and Shape:SolidMolecular weight:374.8IAA-94
CAS:IAA-94 is an inhibitor of chloride channels, it binds channels in bovine kidney cortex microsomes with a Ki value of 1 µM.Formula:C17H18Cl2O4Color and Shape:SolidMolecular weight:357.23NS-3736
CAS:NS-3736 is a chloride channel inhibitor that has been shown to prevent osteoclastic acidification and resorption.Formula:C15H9BrClF3N6OColor and Shape:SolidMolecular weight:461.62BTG-1640
CAS:BTG-1640 is used potentially for the treatment of anxiety and panic disorder.Formula:C15H19NO2Color and Shape:SolidMolecular weight:245.32ANO1-IN-4
CAS:ANO1-IN-4 (Compound 10bm) is a reversible inhibitor of the calcium-activated chloride channel transmembrane protein 16A (TMEM16A, also known as ANO1), with an IC50 of 0.030 µM. It demonstrates good metabolic stability in rat liver microsomes and can inhibit spontaneous contractions in isolated mouse ileum.Formula:C19H19BrF2N2O2SColor and Shape:SolidMolecular weight:457.33Alilusem
CAS:Alilusem is a new diuretic that is beneficial to the clinical treatment of hypertension.Formula:C17H15ClKN2O5SColor and Shape:SolidMolecular weight:433.92NS5818
CAS:NS5818 inhibits ClC.Formula:C23H19Cl2N7O2Purity:98%Color and Shape:SolidMolecular weight:496.35
