Sodium Channel
Sodium channels are essential membrane proteins that allow the passage of sodium ions (Na+) across the cell membrane, generating and propagating electrical signals in neurons, muscle cells, and other excitable tissues. These channels are vital for the initiation and conduction of action potentials, making them crucial in processes such as nerve impulse transmission, muscle contraction, and cardiac function. Dysregulation of sodium channels can lead to neurological disorders, arrhythmias, and chronic pain conditions. At CymitQuimica, we provide a variety of sodium channel modulators to support your research in neurobiology, cardiology, and pain management.
Found 202 products of "Sodium Channel"
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Disopyramide
CAS:<p>Disopyramide, or Triombrin, a class I anti-arrhythmic with membrane-stabilizing effects, has heart depressant, anticholinergic, and anesthetic properties.</p>Formula:C21H29N3OPurity:99.62%Color and Shape:SolidMolecular weight:339.47LTGO-33
CAS:<p>LTGO-33 is a voltage-gated sodium channel NaV1.8 inhibitor that inhibits NaV1.8, NaV1.1-NaV1.7, and NaV1.9.</p>Formula:C21H17F4N3O3SPurity:97.6%Color and Shape:SoildMolecular weight:467.44Veratridine
CAS:<p>Veratridine is a benzoate-cevane found in Veratrum and Schoenocaulon. It activates sodium channels to stay open longer than normal.</p>Formula:C36H51NO11Purity:98.07% - 99.27%Color and Shape:Yellowish-White Amorphous Powder PowderMolecular weight:673.79GpTx-1 TFA
<p>GpTx-1 TFA is a polypeptide NaV1.7 sodium channel antagonist isolated from the venom of the Chilean spider Grammostola porter. It exhibits potent inhibitory activity on the NaV1.7 channel with an IC50 value of 10 nM, demonstrating excellent selectivity over NaV1.4 (IC50 = 0.301 μM) and NaV1.5 (IC50 = 4.20 μM) with >20-fold and >950-fold selectivity, respectively.</p>Color and Shape:Odour SolidLifarizine FA
<p>Lifarizine FA is a sodium channel blocker used in the treatment of neurological disorders and cardiovascular diseases, study of stroke.</p>Formula:C30H34N4O2Purity:99.55%Color and Shape:SolidMolecular weight:482.62Indenebart
<p>Indenebart is a humanized IgG1λ2 monoclonal antibody targeting SNCA, with HumanIgG1lambda2, Isotype Control serving as the corresponding isotype control.</p>Color and Shape:Odour LiquidPF-06456384 trihydrochloride
CAS:<p>PF-06456384 trihydrochloride is a selective NaV1.7 inhibitor acting through protein-ligand binding. intravenous infusion and pain research.</p>Formula:C35H35Cl3F3N7O3S2Purity:99.16%Color and Shape:SolidMolecular weight:829.18Huwentoxin-IV
CAS:<p>Selective NaV1.7 blocker; also inhibits NaV1.2, 1.3; less effect on NaV1.4, 1.5. Binds to neurotoxin site, traps voltage sensor. IC50: 26-338 nM.</p>Formula:C174H278N52O51S6Purity:98%Color and Shape:SolidMolecular weight:4106.79Halazone
CAS:<p>Halazone (Pantocid) is fine white powder with an odor of chlorine. It has been widely used to disinfect drinking water.</p>Formula:C7H5Cl2NO4SPurity:98.64%Color and Shape:Physical Description Fine White Powder With An Odor Of Chlorine (Ntp 1992)Molecular weight:270.09SLC26A3-IN-2
CAS:<p>Vilobelimab (CaCP-29) is a human-mouse chimeric IgG antibody targeting human complement component 5a, a C5a inhibitor that inhibits neutrophil activation.</p>Formula:C19H13ClN2O2SPurity:99.86%Color and Shape:SolidMolecular weight:368.84Zandatrigine
CAS:<p>Zandatrigine (NBI-921352) is a blocker of sodium channel protein type 8 subunit alpha and can be used in studies about nervous system pathologies of epilepsy</p>Formula:C22H25FN4O2S2Purity:99.98%Color and Shape:SolidMolecular weight:460.59Amlenetug
<p>Amlenetug is a humanized IgG1κ antibody targeting SNCA, with its corresponding isotype control being HumanIgG1kappa, Isotype Control.</p>Color and Shape:Odour LiquidMepivacaine hydrochloride
CAS:<p>Mepivacaine hydrochloride (Mepivacaine HCl) is the hydrochloride salt form of mepivacaine, an amide derivative with local anesthetic properties.</p>Formula:C15H22N2O·HClPurity:98.76% - 99.94%Color and Shape:White Or Off White Crystalline PowderMolecular weight:282.81Trapencaine
CAS:<p>Trapencaine is a newly synthesized carbamate type local anesthetic that induces conformational changes in sodium channels on hypertrophic cell membranes.</p>Formula:C22H34N2O3Purity:98.96%Color and Shape:SolidMolecular weight:374.52Zoniporide
CAS:<p>Zoniporide (CP-597396) is an NHE-1 inhibitor that inhibits platelet swelling and can be used in the study of cardiovascular diseases.</p>Formula:C17H16N6OPurity:99.74%Color and Shape:SolidMolecular weight:320.351-(1-Methyl-1h-pyrazol-4-yl)-ethanone
CAS:<p>1-(1-Methyl-1h-pyrazol-4-yl)-ethanone is a high purity biochemical reagent that can be used in research related to life sciences.</p>Formula:C6H8N2OPurity:99.92%Color and Shape:SolidMolecular weight:124.14Benzonatate (PEGn)
CAS:<p>Benzonatate (PEGn) is a unique non-narcotic cough suppressant featuring sodium channel blocking properties and anesthetic effects on respiratory tract stretch receptors.</p>Formula:(C2H4O)nC12H17NO2Color and Shape:Solid5-Tridecanol
CAS:<p>5-Tridecanol blocks ion flux in sodium channels.</p>Formula:C13H28OPurity:97.87%Color and Shape:SolidMolecular weight:200.36APETx2
CAS:<p>ASIC3 inhibitor; IC50: 63 nM (rat), 175 nM (human). Blocks NaV1.8, NaV1.2; analgesic for acid/inflammatory pain.</p>Formula:C196H280N54O61S6Purity:98%Color and Shape:SolidMolecular weight:4561.06Mambalgin 1
CAS:<p>ASIC1a inhibitor; IC50: 192 nM (human), 72 nM (dimer); inactive channel binding; selective; pain response delay.</p>Formula:C272H429N85O84S10Purity:98%Color and Shape:SolidMolecular weight:6554.51
