Sodium Channel
Sodium channels are essential membrane proteins that allow the passage of sodium ions (Na+) across the cell membrane, generating and propagating electrical signals in neurons, muscle cells, and other excitable tissues. These channels are vital for the initiation and conduction of action potentials, making them crucial in processes such as nerve impulse transmission, muscle contraction, and cardiac function. Dysregulation of sodium channels can lead to neurological disorders, arrhythmias, and chronic pain conditions. At CymitQuimica, we provide a variety of sodium channel modulators to support your research in neurobiology, cardiology, and pain management.
Found 202 products of "Sodium Channel"
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λ-Cyhalothrin
CAS:<p>λ-Cyhalothrin (Icon) is a type II synthetic pyrethroid insecticide featuring a high-efficiency, broad-spectrum formula with an α-cyano group.</p>Formula:C23H19ClF3NO3Purity:99.76%Color and Shape:SolidMolecular weight:449.85Rimeporide
CAS:<p>Rimeporide (EMD-87580) (EMD-87580) is a potent and selective Sodium hydrogen exchange 1 (NHE-1) inhibitor.</p>Formula:C11H15N3O5S2Purity:97.66%Color and Shape:SolidMolecular weight:333.38Flecainide hydrochloride
CAS:<p>Flecainide is a medication used to prevent and treat abnormally fast heart rates. This includes ventricular and supraventricular tachycardias.</p>Formula:C17H21ClF6N2O3Purity:97.79%Color and Shape:SolidMolecular weight:450.81Raxatrigine
CAS:<p>Raxatrigine (CNV 1014802) has been investigated for the treatment of Bipolar Disorder and Bipolar Depression.</p>Formula:C18H19FN2O2Purity:98% - 99.43%Color and Shape:SolidMolecular weight:314.35N-Me-aminopyrimidinone9
CAS:<p>N-Me-aminopyrimidinone9 is a sodium channel antagonist</p>Formula:C16H21N3OSPurity:99.21%Color and Shape:SolidMolecular weight:303.42Levobupivacaine
CAS:<p>Levobupivacaine is an amino-amide local anaesthetic drug belonging to the family of n-alkylsubstituted pipecoloxylidide.</p>Formula:C18H28N2OPurity:99.72%Color and Shape:SolidMolecular weight:288.43Propafenone hydrochloride
CAS:<p>Propafenone hydrochloride (Arythmol8) is a classic anti-arrhythmic medication, which treats illnesses associated with rapid heartbeats such as atrial.</p>Formula:C21H27NO3·HClPurity:99.67%Color and Shape:White SolidMolecular weight:377.9Benzocaine xHCl(94-09-7(free base))
<p>Benzocaine shares a common receptor with all othe rLAs in the voltage-gated Na+ channel(IC50 of 0.8 mM tested with a potential of +30 mV).</p>Formula:C9H11NO2·xHClPurity:99.37%Color and Shape:SolidMolecular weight:N/AVX-150
CAS:<p>VX-150 is a highly selective NaV1.8 inhibitor relative to the other sodium channel subtypes (>400-fold).</p>Formula:C21H17F4N2O7PPurity:97.58%Color and Shape:SolidMolecular weight:516.34PF-01247324
CAS:<p>PF-01247324 is a selective and orally bioavailable Nav1.8 channel blocker (IC50: 196 nM).</p>Formula:C13H10Cl3N3OPurity:99.22%Color and Shape:SolidMolecular weight:330.6PF 05089771
CAS:<p>PF 05089771 is a Selective inhibitor of Nav1.7 (IC50 = 11 nM) that interacts with the voltage-sensor domain of domain IV.</p>Formula:C18H12Cl2FN5O3S2Purity:99.03% - 99.42%Color and Shape:SolidMolecular weight:500.35PF-05186462
CAS:<p>PF-05186462 (PF-05150122) is a potent, state-dependent, subtype selective Nav1.7 inhibitor with IC50 of 21 nM, no significant activity against Nav1.5.</p>Formula:C19H10ClF4N5O3S2Purity:99.10% - 99.37%Color and Shape:SolidMolecular weight:531.89Ralfinamide mesylate
CAS:<p>Ralfinamide mesylate (FCE-26742A (mesylate)) is an orally available Na+ channel blocker.</p>Formula:C18H23FN2O5SPurity:99.83%Color and Shape:SolidMolecular weight:398.45Ajmaline
CAS:<p>Ajmaline, a class Ia anti-arrhythmic, diagnoses Brugada syndrome and treats tachycardia; inhibits cardiac Kv1.5/Kv4.3 channels.</p>Formula:C20H26N2O2Purity:99.67% - 99.87%Color and Shape:SolidMolecular weight:326.43ICA-121431
CAS:<p>ICA-121431: a potent Nav1.7 inhibitor (IC50=19 nM for rat), minimal effect on human Nav1.5/Nav1.7.</p>Formula:C23H19N3O3S2Purity:98.06%Color and Shape:SolidMolecular weight:449.55(+)-Kavain
CAS:<p>(+)-Kavain ((R)-KAWAIN) is one of the six major kavalactones found in the Piper methysticum (kava) plant; reversible inhibitor of MAO-B.</p>Formula:C14H14O3Purity:97% - ≥95%Color and Shape:White Fine PowderMolecular weight:230.26Benzamil
CAS:<p>Benzamil blocks ENaC, inhibiting sodium transport (IC50=4 nM) and binds with Kd=5 nM to bovine kidney membranes.</p>Formula:C13H14ClN7OPurity:99.79%Color and Shape:SolidMolecular weight:319.7520(S)-Ginsenoside Rg3
CAS:<p>20(S)-Ginsenoside Rg3 (Rg3) possess an ability to inhibit the lung metastasis of tumor cells via inhibition of the adhesion and invasion of tumor cells.</p>Formula:C42H72O13Purity:98.11% - 99.93%Color and Shape:SolidMolecular weight:785.01Dronedarone
CAS:<p>Dronedarone (SR 33589) is an amiodarone analogue which has an effective and promising treatment for Atrial fibrillation.</p>Formula:C31H44N2O5SPurity:98.85% - 99.58%Color and Shape:SolidMolecular weight:556.76Evenamide
CAS:<p>Evenamide (NW-3509) is a sodium channel blocker. Which shows efficacy in a broad spectrum of rodent models of psychosis, mania, depression, and aggressiveness.</p>Formula:C16H26N2O2Purity:96.74% - 99.15%Color and Shape:SolidMolecular weight:278.39Metaflumizone
CAS:<p>Metaflumizone (BAS-320I) is a sodium channel blocker insecticide.</p>Formula:C24H16F6N4O2Purity:98.73%Color and Shape:SolidMolecular weight:506.40Cyfluthrin
CAS:<p>Cyfluthrin binds to voltage-sensitive sodium channel such as Nav 1.8 sodium channel and modify their gating kinetics, thereby disrupting nerve function of pests</p>Formula:C22H18Cl2FNO3Purity:99.76%Color and Shape:SolidMolecular weight:434.29A-803467
CAS:<p>A-803467 is a selective NaV1.8 channel blocker.</p>Formula:C19H16ClNO4Purity:96.94% - 98%Color and Shape:SolidMolecular weight:357.79Metergoline
CAS:<p>Metergoline (Methergoline) is a dopamine agonist and serotonin antagonist.</p>Formula:C25H29N3O2Purity:99.83% - 99.97%Color and Shape:SolidMolecular weight:403.52Tenapanor
CAS:<p>Tenapanor (RDX 5791), an NHE3 inhibitor, regulates sodium in the gut and kidney with a strong preclinical safety record and minimal side effects.</p>Formula:C50H66Cl4N8O10S2Purity:99.49% - 99.85%Color and Shape:SolidMolecular weight:1145.05Dimethyl lithospermate B
CAS:<p>Dimethyl lithospermate B (dmLSB) is a selective Na+ channel agonist.</p>Formula:C38H34O16Purity:98.34% - 99.62%Color and Shape:SolidMolecular weight:746.67Eslicarbazepine Acetate
CAS:<p>Eslicarbazepine Acetate (Zebinix) is an anticonvulsant medication approved for use as an adjunctive therapy for partial-onset seizures.</p>Formula:C17H16N2O3Purity:99.58% - >99.99%Color and Shape:White To Off-White SolidMolecular weight:296.32Nicainoprol
CAS:<p>Nicainoprol (RU-42924) is a fast-sodium-channel blocking drug. Nicainoprol is a potent antiarrhythmic agent.</p>Formula:C21H27N3O3Purity:99.54%Color and Shape:SolidMolecular weight:369.46Sodium ionophore III
CAS:<p>Sodium ionophore III (ETH2120) is a Na+ ionophore suitable for the test of sodium activity in plasma, serum, and blood.</p>Formula:C34H52N2O4Purity:99.51% - 99.78%Color and Shape:SolidMolecular weight:552.79BI 01383298
CAS:<p>BI 01383298 is a selective inhibitor of the sodium-citrate co-transporter (SLC13A5).</p>Formula:C19H19Cl2FN2O3SPurity:99.71%Color and Shape:SolidMolecular weight:445.34GS967
CAS:<p>GS967 is a potent, and selective inhibitor of cardiac late sodium current (late INa ).</p>Formula:C14H7F6N3OPurity:98% - >99.99%Color and Shape:SolidMolecular weight:347.22Ranolazine
CAS:<p>Ranolazine (RS 43285-003) inhibits calcium uptake, treats chronic angina by targeting sodium/calcium channels to modulate intracellular sodium.</p>Formula:C24H33N3O4Purity:98.13%Color and Shape:White SolidMolecular weight:427.54AZ194
CAS:<p>CRMP2-Ubc9-NaV1.7 inhibitor 194, is a CRMP2-Ubc9-NaV1.7 inhibitor.</p>Formula:C34H31F2N3O3Purity:99.61%Color and Shape:SolidMolecular weight:567.62RY785
CAS:<p>RY785 is a potent and selective inhibitor of voltage-gated potassium channel such as KV2.2 (IC50 = 50 nM). RY785 may be used in pain relief studies.</p>Formula:C21H20N4O2SPurity:99.78%Color and Shape:SolidMolecular weight:392.476-Benzoylheteratisine
CAS:<p>6-Benzoylheteratisine (Heteratisan-14-one, 6-(benzoyloxy)-20-ethyl-8-hydroxy-1-methoxy-4-meth) is a Aconitum alkaloid.</p>Formula:C29H37NO6Purity:99.87%Color and Shape:SolidMolecular weight:495.61Benzonatate
CAS:<p>Benzonatate is an antagonist of sodium channel protein.</p>Formula:C30H53NO11Purity:99.92%Color and Shape:Colorless To Faintly Yellow Oil LiquidMolecular weight:603.74PF-06869206
CAS:<p>PF-06869206 is an oral selective inhibitor of the sodium-phosphate cotransporter NaPi2a (SLC34A1, IC50: 380 nM).</p>Formula:C15H14ClF3N4O2Purity:99.79% - 99.88%Color and Shape:SolidMolecular weight:374.75Levobupivacaine hydrochloride
CAS:<p>Levobupivacaine hydrochloride ((S)-(-)-Bupivacaine monohydrochloride) is a reversible neuronal sodium channel inhibitor, used as a long-acting local anesthetic.</p>Formula:C18H28N2O·HClPurity:99.74%Color and Shape:White Crystalline PowderMolecular weight:324.893-Deoxyaconitine
CAS:<p>3- Deoxyaconitine is a derivative of Aconitine (A189875), which activates tetrodotoxin-sensitive Na+ channels, inducing presynaptic depolarization, thus</p>Formula:C34H47NO10Purity:98.31%Color and Shape:SolidMolecular weight:629.74Ralfinamide
CAS:<p>Ralfinamide (Priralfinamide) is an orally available Na-channel blocker for the treatment of neuropathic pain and other pain conditions.</p>Formula:C17H19FN2O2Purity:99.41%Color and Shape:SolidMolecular weight:302.34Riluzole
CAS:<p>Riluzole (RP-54274) is an anticonvulsant, glutamate antagonist, and prolongs ALS patient survival.</p>Formula:C8H5F3N2OSPurity:99.71% - 99.88%Color and Shape:PowderMolecular weight:234.2N-Formylguanidine
CAS:Controlled ProductFormula:C2H5N3OColor and Shape:Off-WhiteMolecular weight:87.081Benzocaine N-Glucoside (a/b mixture)
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications The N-Glucoside of Benzocaine (B202970) with anesthetic activity. A potential sun-screening agent.<br>References Rybczynska, B. et al.: Parfum. Kosm., 48, 125 (1967); Nikolin, A. et al.: Glas. Hemi. Tehnol. Bosne Herceg., 16, 93 (1968);<br></p>Formula:C15H21NO7Color and Shape:NeatMolecular weight:327.33Propoxycaine hydrochloride
CAS:<p>Propoxycaine hydrochloride is an ester local anesthetic that inhibits voltage-gated sodium channels, modulates nerve impulses, and induces loss of sensation.</p>Formula:C16H27ClN2O3Purity:97.25%Color and Shape:SolidMolecular weight:330.85Eleclazine
CAS:<p>Eleclazine (GS-6615) is a novel and selective voltage-gated sodium channel inhibitor with antiarrhythmic properties that reduces peak sodium current (INaP).</p>Formula:C21H16F3N3O3Purity:98.67%Color and Shape:SolidMolecular weight:415.37Deacetamide Acetonitrile-pentisomide
CAS:Controlled Product<p>Applications Deacetamide Acetonitrile-pentisomide is an intermediate in the synthesis of Pentisomide (P275600). Pentisomide is a sodium channel blocker; derivative of disopyramide. Antiarrhythmic (class I).<br>References Kuhlkamp, V., et al.: Int. J. Cardiol., 36, 69 (1992); Yuan, S., et al.: Cardiovasc. Drug Rev., 11, 74 (1993)<br></p>Formula:C19H31N3Color and Shape:NeatMolecular weight:301.47N-(Chloroacetyl)-2,5-dimethylaniline
CAS:Controlled Product<p>Applications N-(Chloroacetyl)-2,5-dimethylaniline is an intermediate in the synthesis of impurities of Lidocaine (L397800), an anesthetic local agent and antiarrythmic class IB agent.<br>References Groningsson, K., et al.: Anal. Profiles Drug Subs., 14, 207 (1985), Davies, P.S., et al.: Drugs, 64, 937 (2004),<br></p>Formula:C10H12ClNOColor and Shape:NeatMolecular weight:197.663-(2-Chloropropionyl)amino-4-methyl-2-methoxycarbonylthiophene
CAS:Controlled Product<p>Applications 3-(2-Chloropropionyl)amino-4-methyl-2-methoxycarbonylthiophene is an intermediate in the synthesis of Articaine-d7 Hydrochloride which is the labelled form of Articaine Hydrochloride (A777905). Articaine Hydrochloride is the Hydrochloride Salt of Articaine (A777900). Articaine is an amide based short-acting local anesthetic use for regional anaesthesia in day-case settings such arthroscopy, hand, food surgery and in dentistry.<br>References Malamed, S.F., et al.: J. Am. Dent. Assoc., 132, 177 (2001); Luan, F., et al.: Bioorg. Med. Chem., 21, 1870 (2013)<br></p>Formula:C10H12ClNO3SColor and Shape:NeatMolecular weight:261.73Methocarbamol D5
CAS:<p>Methocarbamol is a central muscle relaxant. Methocarbamol D5 is deuterium labeled Methocarbamol.</p>Formula:C11H15NO5Purity:98%Color and Shape:SolidMolecular weight:246.27Propafenone D7 hydrochloride
CAS:<p>Propafenone D7 hydrochloride is the deuterium labeled Propafenone, and is a classic anti-arrhythmic medication.</p>Formula:C21H28ClNO3Purity:98%Color and Shape:SolidMolecular weight:384.95
