Sodium Channel
Sodium channels are essential membrane proteins that allow the passage of sodium ions (Na+) across the cell membrane, generating and propagating electrical signals in neurons, muscle cells, and other excitable tissues. These channels are vital for the initiation and conduction of action potentials, making them crucial in processes such as nerve impulse transmission, muscle contraction, and cardiac function. Dysregulation of sodium channels can lead to neurological disorders, arrhythmias, and chronic pain conditions. At CymitQuimica, we provide a variety of sodium channel modulators to support your research in neurobiology, cardiology, and pain management.
Found 273 products for "Sodium Channel".
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ProTx-III
ProTx-III, a spider venom peptide derived from the Peruvian green velvet tarantula, functions as a selective and potent inhibitor of the voltage-gated sodiumFormula:C162H246N52O43S6Purity:98%Color and Shape:SolidMolecular weight:3802.4mHuwentoxin-IV
mHuwentoxin-IV, a naturally modified form of Huwentoxin-IV, selectively inhibits tetrodotoxin-sensitive (TTX-S) voltage-gated sodium channels in dorsal rootFormula:C174H276N52O50S6Purity:98%Color and Shape:SolidMolecular weight:4088.76m3-Huwentoxin IV
m3-Huwentoxin IV (m3-HwTx-IV) is a potent inhibitor of sodium channels (NaV), exhibiting half-maximal inhibitory concentrations (IC50s) of 3.3 nM for hNaV1.7, 6Formula:C170H271N53O46S6Purity:98%Color and Shape:SolidMolecular weight:3985.69Mambalgin-2
Mambalgin-2 (Mamb-2), a venom peptide sourced from the African black mamba, acts as an inhibitor of acid-sensitive ion channels (ASICs).Formula:C272H431N85O83S10Purity:98%Color and Shape:SolidMolecular weight:6540.5Aah II
Aah II, a sodium channel modulator, is a toxin derived from the venom of the scorpion Androctonus australis [1] [2].Formula:C313H457N89O95S8Purity:98%Color and Shape:SolidMolecular weight:7243.04µ-Conotoxin SIIIA
CAS:μ-Conotoxin SIIIA, a tetrodotoxin (TTX)-resistant sodium channel blocker, is a toxic peptide derived from Conus snail venom.Formula:C83H123N33O27S6Purity:98%Color and Shape:SolidMolecular weight:2207.46LTGO-33
CAS:LTGO-33 is a voltage-gated sodium channel NaV1.8 inhibitor that inhibits NaV1.8, NaV1.1-NaV1.7, and NaV1.9.Formula:C21H17F4N3O3SPurity:97.6%Color and Shape:White SolidMolecular weight:467.44Nav1.2-IN-2
CAS:Nav1.2-IN-2 is a Nav1.2 inhibitor, IC₅₀=0.18 μM for inactivated Nav1.2, inhibits Veratridine-induced calcium influx, epilepsy.Formula:C17H26N2O4Purity:99.97%Color and Shape:White SolidMolecular weight:322.4Sodium Channel inhibitor 5
Sodium Channel inhibitor5 (compound 7d) is a potent sodium channel inhibitor with an IC50 of 2.7 μM, playing a significant role in antiarrhythmic research.Formula:C24H23F3N4O2Color and Shape:SolidMolecular weight:456.17731Sodium Channel Targeted Library
A unique collection of xnum sodium channel blockers and agonists for high throughput and high content screening;Color and Shape:Odour SolidRef: TM-L7400
1mgTo inquire10μL*10mM (DMSO)To inquire20μL*10mM (DMSO)To inquire30μL*10mM (DMSO)To inquire50μL*10mM (DMSO)To inquire100μL*10mM (DMSO)To inquire250μL*10mM (DMSO)To inquireAnthopleurin-A
CAS:Anthopleurin-A, a sodium channel toxin, is selective for cardiac channels and has a cardiotonic effect. It can be isolated from the sea anemone [1] [2].Formula:C220H326N64O67S6Color and Shape:SolidMolecular weight:5131.72ETD001
CAS:ETD001 is a long-acting ENaC inhibitor with an IC50 value of 57.5 nM in HBE cells. It is applicable for research in cystic fibrosis.Formula:C41H57F6N9O16Color and Shape:SolidMolecular weight:1045.93µ-Conotoxin BuIIIA
μ-Conotoxin BuIIIA (Mu-Conotoxin BuIIIA), a toxin derived from Cone snail venom, functions as a voltage-gated sodium channel (VGSC) blocker.Formula:C106H172N44O31S6Purity:98%Color and Shape:SolidMolecular weight:2751.17Pe1b
Pe1b (μ-TrTx-Pe1b) is a selective inhibitor of the NaV1.7 channel, exhibiting an inhibitory concentration 50 (IC50) value of 167 nanomolar (nM) [1].Formula:C175H237N47O49S6Purity:98%Color and Shape:SolidMolecular weight:3975.43Mepivacaine hydrochloride
CAS:Mepivacaine hydrochloride (Mepivacaine HCl) is the hydrochloride salt form of mepivacaine, an amide derivative with local anesthetic properties.Formula:C15H22N2O·HClPurity:99.80% - 99.96%Color and Shape:White Or Off White Crystalline PowderMolecular weight:282.81Anthopleurin-C
Anthopleurin-C (APE 2-1) is a cardiotonic polypeptide exhibiting a potent positive inotropic effect [1].Formula:C210H316N62O61S6Purity:98%Color and Shape:SolidMolecular weight:4877.52Zandatrigine
CAS:Zandatrigine (NBI-921352) is a blocker of sodium channel protein type 8 subunit alpha and can be used in studies about nervous system pathologies of epilepsyFormula:C22H25FN4O2S2Purity:99.98%Color and Shape:SolidMolecular weight:460.59Ref: TM-T39630
1mg111.00€2mg164.00€1mL*10mM (DMSO)264.00€5mg268.00€10mg439.00€25mg707.00€50mg1,009.00€100mg1,333.00€μ-Conotoxin PIIIA
CAS:μ-Conotoxin PIIIA, isolated from Conus purpurascens [1] [2], is a blocker of the sodium channel NaV 1.4.Formula:C103H166N40O28S6Purity:98%Color and Shape:SolidMolecular weight:2605.06Benzonatate (PEGn)
CAS:Benzonatate (PEGn) is a unique non-narcotic cough suppressant featuring sodium channel blocking properties and anesthetic effects on respiratory tract stretch receptors.Formula:(C2H4O)nC12H17NO2Color and Shape:SolidPterinotoxin-2
Pterinotoxin-2 is a peptide toxin that acts as a sodium channel inhibitor [1].Formula:C156H237N45O42S7Purity:98%Color and Shape:SolidMolecular weight:3639.28Pterinotoxin-1
Pterinotoxin-1 is a peptide toxin that functions as an inhibitor of sodium channels [1].Formula:C163H251N49O53S7Purity:98%Color and Shape:SolidMolecular weight:3969.49BmK-M1
BmK-M1, a scorpion-derived toxin, consists of a 64-amino acid polypeptide stabilized by four disulfide bridges.Formula:C313H467N91O91S8Purity:98%Color and Shape:SolidMolecular weight:7217.135-Tridecanol
CAS:5-Tridecanol blocks ion flux in sodium channels.Formula:C13H28OPurity:97.87%Color and Shape:SolidMolecular weight:200.36(R)-Duloxetine
CAS:(R)-Duloxetine, an isomer of Duloxetine, induces tonic and use-dependent blockade of neuronal Na+ channels. This compound is utilized in pain research.Formula:C18H19NOSColor and Shape:SolidMolecular weight:297.42Trapencaine
CAS:Trapencaine is a newly synthesized carbamate type local anesthetic that induces conformational changes in sodium channels on hypertrophic cell membranes.Formula:C22H34N2O3Purity:97.68%Color and Shape:SolidMolecular weight:374.52Zoniporide
CAS:Zoniporide (CP-597396) is an NHE-1 inhibitor that inhibits platelet swelling and can be used in the study of cardiovascular diseases.Formula:C17H16N6OPurity:99.74%Color and Shape:SolidMolecular weight:320.35PF-06456384 trihydrochloride
CAS:PF-06456384 trihydrochloride is a selective NaV1.7 inhibitor acting through protein-ligand binding. intravenous infusion and pain research.Formula:C35H35Cl3F3N7O3S2Purity:99.16%Color and Shape:White SolidMolecular weight:829.18Nav1.7-IN-18
Nav1.7-IN-18 (Compound 31) is a Nav1.7 inhibitor with a Ki value of 4.9 nM and an IC50 of 13 nM, demonstrating analgesic effects in transgenic mice with inherited erythromelalgia (IEM).Formula:C30H33Cl2F2NO4Color and Shape:SolidMolecular weight:580.49Solpecainol
CAS:solpecainol is a sodium channel blocker used in the study of neurological and cardiovascular diseases.Formula:C18H23NO3Purity:99.71%Color and Shape:White OilMolecular weight:301.38Batrachotoxin
CAS:Batrachotoxin (BTX), a potent neurotoxin and cardiotoxin, is found in the skin of the Colombian dart frog (Phyllobates aurotaenia). As an activator of sodium channels (sodium channel), it interferes with normal sodium channel closure by binding to voltage-gated sodium channels (sodium channel) on the cell membrane. This interaction causes a continuous influx of sodium ions into the cells, leading to persistent depolarization.Formula:C31H42N2O6Color and Shape:SolidMolecular weight:538.67CL-424032
CAS:CL-424032 is a defined pyrazolo[5-a]pyrimidine derivative that functions as a potent sodium channel inhibitor, effectively blocking sodium ion flux across cellular membranes. CL-424032 is extensively utilized in pharmacology and drug discovery research to investigate sodium channel–dependent excitability, signal propagation, and therapeutic modulation of ion channel activity.Formula:C12H7F3N4O2Purity:99.90%Color and Shape:Yellow SolidMolecular weight:296.21Ethacizine hydrochloride
CAS:Ethacizine hydrochloride (NIK-244) has antiarrhythmic activity and can be used to study arrhythmias and myocardial infarction.Formula:C22H28ClN3O3SPurity:98.08% - 98.08%Color and Shape:SolidMolecular weight:449.99PF-04856264
CAS:PF-04856264 is a Nav1.7 blocker.,modulates intracellular Ca 2+ signaling and chondrocyte secretome, raises the threshold of mechanical pain analgesic.Formula:C20H15N5O3S2Purity:97.43%Color and Shape:White SolidMolecular weight:437.5Ref: TM-T33943
1mg50.00€5mg105.00€1mL*10mM (DMSO)117.00€10mg170.00€25mg340.00€50mg532.00€100mg893.00€Mexiletine-D6 hydrochloride
CAS:Mexiletine D6 hydrochloride is a non-selective voltage-gated sodium channel blocker,is a Class IB antianhythmic.Formula:C11H18ClNOPurity:98%Color and Shape:SolidMolecular weight:221.76Dibucaine hydrochloride
CAS:Dibucaine hydrochloride (Cinchocaine hydrochloride), a long-acting local amide anestheticsis, is usually used for surface anesthesia.Formula:C20H30ClN3O2Purity:99.66%Color and Shape:White PowderMolecular weight:379.92AM-2099
CAS:AM-2099 is a selective voltage-gated sodium channel Nav1.7 inhibitor used in pain research.Formula:C19H13F3N4O3S2Color and Shape:SolidMolecular weight:466.46Clopamide (Standard)
CAS:Clopamide (Standard) is the standard substance of Clopamide, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Clopamide (Brinaldix) is a piperidine and sulfamoylbenzamide-based diuretic with thiazide-like diuretic activity.Formula:C14H20ClN3O3SMolecular weight:345.84Bulleyaconitine A
CAS:Bulleyaconitine A, an analgesic and antiinflammatory drug isolated from Aconitum plants, has several potential targets, such as voltage-gated Na+ channels.Formula:C35H49NO9Purity:99.56% - 99.76%Color and Shape:White SolidMolecular weight:627.763,3-Diethylthiacarbocyanine iodide
CAS:3, 3-diethylthiacarbocyanine iodide is a cyanine dye. Can be used for photochemical methods.Formula:C21H21IN2S2Purity:99.79%Color and Shape:SolidMolecular weight:492.4410,11-Dihydro-10-hydroxycarbamazepine-D4
CAS:10,11-Dihydro-10-hydroxycarbamazepine-d4 is a deuterated compound of 10,11-Dihydro-10-hydroxycarbamazepine.Formula:C15H10D4N2O2Color and Shape:SolidMolecular weight:258.31Triamterene-D5
CAS:Triamterene D5 is a deuterium-labeled Triamterene and can block epithelial Na+ channel (ENaC) in a voltage-dependent manner, used as a mild diuretic.Formula:C12H11N7Purity:98%Color and Shape:SolidMolecular weight:258.29Mepivacaine
CAS:Mepivacaine (Carbocaine) is an amide local anesthetic, blocking sodium channels for nerve blocks and epidurals.Formula:C15H22N2OPurity:99.86%Color and Shape:White SolidMolecular weight:246.35BI-9627
CAS:BI-9627 is an inhibitor of sodium-hydrogen exchanger isoform 1 (NHE1) (EC50: 31 nM).Formula:C16H19F3N4O2Purity:99.77%Color and Shape:White SolidMolecular weight:356.34Ajmaline
CAS:Ajmaline, a class Ia anti-arrhythmic, diagnoses Brugada syndrome and treats tachycardia; inhibits cardiac Kv1.5/Kv4.3 channels.Formula:C20H26N2O2Purity:99.67% - 99.87%Color and Shape:White SolidMolecular weight:326.44Ranolazine
CAS:Ranolazine (RS 43285-003) inhibits calcium uptake, treats chronic angina by targeting sodium/calcium channels to modulate intracellular sodium.Formula:C24H33N3O4Purity:98.13%Color and Shape:White SolidMolecular weight:427.54Ropivacaine hydrochloride monohydrate
CAS:Ropivacaine hydrochloride monohydrate (LEA-103 HCl) is an anaesthetic agent and blocks impulse conduction through inhibiting sodium ion influx reversibly.Formula:C17H29ClN2O2Purity:99.94% - 99.95%Color and Shape:White SolidMolecular weight:328.88GNE-131
CAS:GNE-131 is a potent and specific inhibitor of human sodium channel NaV1.7 (IC50: 3 nM).Formula:C23H30N4O3SPurity:98.54% - 99.59%Color and Shape:SolidMolecular weight:442.57Ref: TM-TQ0014
1mg105.00€5mg250.00€1mL*10mM (DMSO)268.00€10mg356.00€25mg597.00€50mg835.00€100mg1,108.00€Flecainide acetate
CAS:Flecainide acetate (R-818) is a class Ic antiarrhythmic agent used to prevent and treat tachyarrhythmias (abnormal fast rhythms of the heart).Formula:C19H24F6N2O5Purity:99.42%Color and Shape:SolidMolecular weight:474.39Fosphenytoin disodium
CAS:Fosphenytoin disodium (ACC-9653) is a prodrug of phenytoin that is rapidly converted to phenytoin, a voltage-gated sodium channel blockerFormula:C16H13N2Na2O6PPurity:99.97%Color and Shape:White SolidMolecular weight:406.24DS-1971a
CAS:DS-1971a is a highly potent and selective NaV1.7 inhibitor. DS-1971a exhibits a favorable toxicological profile and analgesic effects.Formula:C20H21ClFN5O3SPurity:99.66%Color and Shape:White SolidMolecular weight:465.93
