Sodium Channel
Sodium channels are essential membrane proteins that allow the passage of sodium ions (Na+) across the cell membrane, generating and propagating electrical signals in neurons, muscle cells, and other excitable tissues. These channels are vital for the initiation and conduction of action potentials, making them crucial in processes such as nerve impulse transmission, muscle contraction, and cardiac function. Dysregulation of sodium channels can lead to neurological disorders, arrhythmias, and chronic pain conditions. At CymitQuimica, we provide a variety of sodium channel modulators to support your research in neurobiology, cardiology, and pain management.
Found 397 products for "Sodium Channel".
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Ceratotoxin-1
Ceratotoxin-1 (CcoTx1) is a peptide toxin that functions as an inhibitor of various voltage-gated sodium channel subtypes.Formula:C172H256N52O50S6Purity:98%Color and Shape:SolidMolecular weight:4044.58Benzonatate (PEGn)
CAS:Benzonatate (PEGn) is a unique non-narcotic cough suppressant featuring sodium channel blocking properties and anesthetic effects on respiratory tract stretch receptors.Formula:(C2H4O)nC12H17NO2Color and Shape:SolidMambalgin 1
CAS:ASIC1a inhibitor; IC50: 192 nM (human), 72 nM (dimer); inactive channel binding; selective; pain response delay.Formula:C272H429N85O84S10Purity:98%Color and Shape:SolidMolecular weight:6554.51XPC-7724
XPC-7724 is a selective inhibitor of the Nav1.6 channel, with an IC50 value of 0.078 μM. It is useful in research related to neurological disorders.Formula:C25H30FN5O2SMolecular weight:483.21042Pterinotoxin-1
Pterinotoxin-1 is a peptide toxin that functions as an inhibitor of sodium channels [1].Formula:C163H251N49O53S7Purity:98%Color and Shape:SolidMolecular weight:3969.49Veratridine
CAS:Veratridine is a benzoate-cevane found in Veratrum and Schoenocaulon. It activates sodium channels to stay open longer than normal.Formula:C36H51NO11Purity:98.07% - 99.27%Color and Shape:SolidMolecular weight:673.79Ion Channel Targeted Library
A unique collection of xnum compounds targeting ion channels for research in ion channels-related diseases and ion channel drug discovery;Color and Shape:Odour SolidRef: TM-L2300
1mgTo inquire10μL*10mM (DMSO)To inquire20μL*10mM (DMSO)To inquire30μL*10mM (DMSO)To inquire50μL*10mM (DMSO)To inquire100μL*10mM (DMSO)To inquire250μL*10mM (DMSO)To inquireSolpecainol
CAS:solpecainol is a sodium channel blocker used in the study of neurological and cardiovascular diseases.Formula:C18H23NO3Purity:99.71%Color and Shape:White OilMolecular weight:301.38GpTx-1
CAS:GpTx-1 exhibits potent selectivity as a NaV1.7 antagonist, demonstrating an inhibition concentration (IC50) of 10 nM [1].Formula:C176H271N53O45S7Purity:98%Color and Shape:SolidMolecular weight:4073.82Trapencaine
CAS:Trapencaine is a newly synthesized carbamate type local anesthetic that induces conformational changes in sodium channels on hypertrophic cell membranes.Formula:C22H34N2O3Purity:97.68%Color and Shape:SolidMolecular weight:374.52Sodium Channel Targeted Library
A unique collection of xnum sodium channel blockers and agonists for high throughput and high content screening;Color and Shape:Odour SolidRef: TM-L7400
1mgTo inquire10μL*10mM (DMSO)To inquire20μL*10mM (DMSO)To inquire30μL*10mM (DMSO)To inquire50μL*10mM (DMSO)To inquire100μL*10mM (DMSO)To inquire250μL*10mM (DMSO)To inquireSodium Channel inhibitor 5
Sodium Channel inhibitor5 (compound 7d) is a potent sodium channel inhibitor with an IC50 of 2.7 μM, playing a significant role in antiarrhythmic research.Formula:C24H23F3N4O2Color and Shape:SolidMolecular weight:456.17731Nav1.8-IN-6
Nav1.8-IN-6 (Compound 2j) is a novel pyridinone amide Nav1.8 channel inhibitor with IC50 values of 513.33 nM in the resting state and 471.81 nM in the partially activated state. Nav1.8-IN-6 also exhibits analgesic activity.Formula:C19H17F6N3O2Color and Shape:SolidMolecular weight:433.1225ProTx II
CAS:Selective NaV1.7 inhibitor, alters activation, reduces current, 100x more selective for 1.7 over other Na+ channels.Formula:C168H250N46O41S8Purity:98%Color and Shape:SolidMolecular weight:3826.59Zoniporide
CAS:Zoniporide (CP-597396) is an NHE-1 inhibitor that inhibits platelet swelling and can be used in the study of cardiovascular diseases.Formula:C17H16N6OPurity:99.78%Color and Shape:SolidMolecular weight:320.35APETx2
CAS:ASIC3 inhibitor; IC50: 63 nM (rat), 175 nM (human). Blocks NaV1.8, NaV1.2; analgesic for acid/inflammatory pain.Formula:C196H280N54O61S6Purity:98%Color and Shape:SolidMolecular weight:4561.06Batrachotoxin
CAS:Batrachotoxin (BTX), a potent neurotoxin and cardiotoxin, is found in the skin of the Colombian dart frog (Phyllobates aurotaenia). As an activator of sodium channels (sodium channel), it interferes with normal sodium channel closure by binding to voltage-gated sodium channels (sodium channel) on the cell membrane. This interaction causes a continuous influx of sodium ions into the cells, leading to persistent depolarization.Formula:C31H42N2O6Color and Shape:SolidMolecular weight:538.67Anthopleurin-A
CAS:Anthopleurin-A, a sodium channel toxin, is selective for cardiac channels and has a cardiotonic effect. It can be isolated from the sea anemone [1] [2].Formula:C220H326N64O67S6Color and Shape:SolidMolecular weight:5131.72Tap1a
Theraphotoxin-Tap1a (Tap1a) is a spider venom-derived peptide that acts as an inhibitor of sodium channels, displaying IC50 values of 80 nM for Na v 1.7 and 301Formula:C174H258N52O55S7Purity:98%Color and Shape:SolidMolecular weight:4182.68Nav1.2-IN-2
CAS:Nav1.2-IN-2 is a Nav1.2 inhibitor, IC₅₀=0.18 μM for inactivated Nav1.2, inhibits Veratridine-induced calcium influx, epilepsy.Formula:C17H26N2O4Purity:99.97%Color and Shape:White SolidMolecular weight:322.4
