Sodium Channel
Sodium channels are essential membrane proteins that allow the passage of sodium ions (Na+) across the cell membrane, generating and propagating electrical signals in neurons, muscle cells, and other excitable tissues. These channels are vital for the initiation and conduction of action potentials, making them crucial in processes such as nerve impulse transmission, muscle contraction, and cardiac function. Dysregulation of sodium channels can lead to neurological disorders, arrhythmias, and chronic pain conditions. At CymitQuimica, we provide a variety of sodium channel modulators to support your research in neurobiology, cardiology, and pain management.
Found 202 products of "Sodium Channel"
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APETx2
CAS:<p>ASIC3 inhibitor; IC50: 63 nM (rat), 175 nM (human). Blocks NaV1.8, NaV1.2; analgesic for acid/inflammatory pain.</p>Formula:C196H280N54O61S6Purity:98%Color and Shape:SolidMolecular weight:4561.06Mambalgin 1
CAS:<p>ASIC1a inhibitor; IC50: 192 nM (human), 72 nM (dimer); inactive channel binding; selective; pain response delay.</p>Formula:C272H429N85O84S10Purity:98%Color and Shape:SolidMolecular weight:6554.51Analgesic agent-2
<p>Analgesic Agent-2, a selective orally active inhibitor of the NaV1.8 channel, demonstrates an IC50 of 50.18 nM in HEK293 cells that stably express the human</p>Formula:C21H21ClF2N4O2Purity:98%Color and Shape:SolidMolecular weight:434.87ProTx II
CAS:<p>Selective NaV1.7 inhibitor, alters activation, reduces current, 100x more selective for 1.7 over other Na+ channels.</p>Formula:C168H250N46O41S8Purity:98%Color and Shape:SolidMolecular weight:3826.59PF-06456384 trihydrochloride
CAS:<p>PF-06456384 trihydrochloride is a selective NaV1.7 inhibitor acting through protein-ligand binding. intravenous infusion and pain research.</p>Formula:C35H35Cl3F3N7O3S2Purity:99.16%Color and Shape:SolidMolecular weight:829.18Ion Channel Targeted Library
<p>A unique collection of 931 compounds targeting ion channels for research in ion channels-related diseases and ion channel drug discovery;</p>Color and Shape:Odour SolidHuwentoxin-IV
CAS:<p>Selective NaV1.7 blocker; also inhibits NaV1.2, 1.3; less effect on NaV1.4, 1.5. Binds to neurotoxin site, traps voltage sensor. IC50: 26-338 nM.</p>Formula:C174H278N52O51S6Purity:98%Color and Shape:SolidMolecular weight:4106.79OD1
<p>Activates rat Nav1.7, human Nav1.4, rat Nav1.6 (EC50: 7, 10, 47 nM); minimal on Nav1.2, 1.3, 1.5 (EC50 >3 μM); blocks fast inactivation; triggers pain.</p>Formula:C308H466N90O95S8Purity:98%Color and Shape:SolidMolecular weight:7206.1Phrixotoxin 3
CAS:<p>Potent NaV blocker: IC50 - 0.6 nM (NaV1.2), 42 nM (NaV1.3), 72 nM (NaV1.5); voltage-dependent inhibition.</p>Formula:C176H269N51O48S6Purity:98%Color and Shape:SolidMolecular weight:4059.74Zandatrigine
CAS:<p>Zandatrigine (NBI-921352) is a blocker of sodium channel protein type 8 subunit alpha and can be used in studies about nervous system pathologies of epilepsy</p>Formula:C22H25FN4O2S2Purity:99.98%Color and Shape:SolidMolecular weight:460.59Benzonatate (PEGn)
CAS:<p>Benzonatate (PEGn) is a unique non-narcotic cough suppressant featuring sodium channel blocking properties and anesthetic effects on respiratory tract stretch receptors.</p>Formula:(C2H4O)nC12H17NO2Color and Shape:SolidSodium Channel Targeted Library
<p>A unique collection of xnum sodium channel blockers and agonists for high throughput and high content screening;</p>Color and Shape:Odour SolidLifarizine FA
<p>Lifarizine FA is a sodium channel blocker used in the treatment of neurological disorders and cardiovascular diseases, study of stroke.</p>Formula:C30H34N4O2Purity:99.55%Color and Shape:SolidMolecular weight:482.62GX 201
CAS:<p>GX 201 is a selective NaV1.7 inhibitor, IC50 of < 3.2 nM for hNaV1.7.</p>Formula:C25H27ClF4N2O4SPurity:99.81%Color and Shape:SolidMolecular weight:563Solpecainol
CAS:<p>solpecainol is a sodium channel blocker used in the study of neurological and cardiovascular diseases.</p>Formula:C18H23NO3Purity:99.71%Color and Shape:SoildMolecular weight:301.38Mepivacaine hydrochloride
CAS:<p>Mepivacaine hydrochloride (Mepivacaine HCl) is the hydrochloride salt form of mepivacaine, an amide derivative with local anesthetic properties.</p>Formula:C15H22N2O·HClPurity:98.76% - 99.94%Color and Shape:White Or Off White Crystalline PowderMolecular weight:282.81Nav1.7-IN-18
<p>Nav1.7-IN-18 (Compound 31) is a Nav1.7 inhibitor with a Ki value of 4.9 nM and an IC50 of 13 nM, demonstrating analgesic effects in transgenic mice with inherited erythromelalgia (IEM).</p>Formula:C30H33Cl2F2NO4Color and Shape:SolidMolecular weight:580.49ProTx II TFA
<p>ProTx-II TFA is a potent and highly selective Nav1.7 sodium channel blocker, exhibiting an IC50 of 0.3 nM and demonstrating at least 100-fold selectivity over</p>Formula:C168H250N46O41S8·xC2HF3O2Purity:98%Color and Shape:SolidMolecular weight:3826.59 (free base)Mexiletine-d6 hydrochloride
CAS:<p>Mexiletine D6 hydrochloride is a non-selective voltage-gated sodium channel blocker,is a Class IB antianhythmic.</p>Formula:C11H18ClNOPurity:98%Color and Shape:SolidMolecular weight:221.76AM-2099
CAS:<p>AM-2099 is a selective voltage-gated sodium channel Nav1.7 inhibitor used in pain research.</p>Formula:C19H13F3N4O3S2Color and Shape:SolidMolecular weight:466.46
