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Sodium Channel

Sodium Channel

Sodium channels are essential membrane proteins that allow the passage of sodium ions (Na+) across the cell membrane, generating and propagating electrical signals in neurons, muscle cells, and other excitable tissues. These channels are vital for the initiation and conduction of action potentials, making them crucial in processes such as nerve impulse transmission, muscle contraction, and cardiac function. Dysregulation of sodium channels can lead to neurological disorders, arrhythmias, and chronic pain conditions. At CymitQuimica, we provide a variety of sodium channel modulators to support your research in neurobiology, cardiology, and pain management.

Found 202 products of "Sodium Channel"

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  • λ-Cyhalothrin
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    λ-Cyhalothrin

    CAS:
    <p>λ-Cyhalothrin (Icon) is a type II synthetic pyrethroid insecticide featuring a high-efficiency, broad-spectrum formula with an α-cyano group.</p>
    Formula:C23H19ClF3NO3
    Purity:99.76%
    Color and Shape:Solid
    Molecular weight:449.85

    Ref: TM-T27794

  • Rimeporide
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    Rimeporide

    CAS:
    <p>Rimeporide (EMD-87580) (EMD-87580) is a potent and selective Sodium hydrogen exchange 1 (NHE-1) inhibitor.</p>
    Formula:C11H15N3O5S2
    Purity:97.66%
    Color and Shape:Solid
    Molecular weight:333.38

    Ref: TM-T5319

  • Flecainide hydrochloride
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    Flecainide hydrochloride

    CAS:
    <p>Flecainide is a medication used to prevent and treat abnormally fast heart rates. This includes ventricular and supraventricular tachycardias.</p>
    Formula:C17H21ClF6N2O3
    Purity:97.79%
    Color and Shape:Solid
    Molecular weight:450.81

    Ref: TM-T8581

  • Raxatrigine
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    Raxatrigine

    CAS:
    <p>Raxatrigine (CNV 1014802) has been investigated for the treatment of Bipolar Disorder and Bipolar Depression.</p>
    Formula:C18H19FN2O2
    Purity:98% - 99.43%
    Color and Shape:Solid
    Molecular weight:314.35

    Ref: TM-T2342

  • N-Me-aminopyrimidinone9
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    N-Me-aminopyrimidinone9

    CAS:
    <p>N-Me-aminopyrimidinone9 is a sodium channel antagonist</p>
    Formula:C16H21N3OS
    Purity:99.21%
    Color and Shape:Solid
    Molecular weight:303.42

    Ref: TM-T8444

  • Levobupivacaine
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    Levobupivacaine

    CAS:
    <p>Levobupivacaine is an amino-amide local anaesthetic drug belonging to the family of n-alkylsubstituted pipecoloxylidide.</p>
    Formula:C18H28N2O
    Purity:99.72%
    Color and Shape:Solid
    Molecular weight:288.43

    Ref: TM-T1787

  • Propafenone hydrochloride
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    Propafenone hydrochloride

    CAS:
    <p>Propafenone hydrochloride (Arythmol8) is a classic anti-arrhythmic medication, which treats illnesses associated with rapid heartbeats such as atrial.</p>
    Formula:C21H27NO3·HCl
    Purity:99.67%
    Color and Shape:White Solid
    Molecular weight:377.9

    Ref: TM-T6955

  • Benzocaine xHCl(94-09-7(free base))
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    Benzocaine xHCl(94-09-7(free base))

    <p>Benzocaine shares a common receptor with all othe rLAs in the voltage-gated Na+ channel(IC50 of 0.8 mM tested with a potential of +30 mV).</p>
    Formula:C9H11NO2·xHCl
    Purity:99.37%
    Color and Shape:Solid
    Molecular weight:N/A

    Ref: TM-T6782L

  • VX-150
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    VX-150

    CAS:
    <p>VX-150 is a highly selective NaV1.8 inhibitor relative to the other sodium channel subtypes (&gt;400-fold).</p>
    Formula:C21H17F4N2O7P
    Purity:97.58%
    Color and Shape:Solid
    Molecular weight:516.34

    Ref: TM-T9683

  • PF-01247324
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    PF-01247324

    CAS:
    <p>PF-01247324 is a selective and orally bioavailable Nav1.8 channel blocker (IC50: 196 nM).</p>
    Formula:C13H10Cl3N3O
    Purity:99.22%
    Color and Shape:Solid
    Molecular weight:330.6

    Ref: TM-T4490

  • PF 05089771
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    PF 05089771

    CAS:
    <p>PF 05089771 is a Selective inhibitor of Nav1.7 (IC50 = 11 nM) that interacts with the voltage-sensor domain of domain IV.</p>
    Formula:C18H12Cl2FN5O3S2
    Purity:99.03% - 99.42%
    Color and Shape:Solid
    Molecular weight:500.35

    Ref: TM-T7502L

  • PF-05186462
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    PF-05186462

    CAS:
    <p>PF-05186462 (PF-05150122) is a potent, state-dependent, subtype selective Nav1.7 inhibitor with IC50 of 21 nM, no significant activity against Nav1.5.</p>
    Formula:C19H10ClF4N5O3S2
    Purity:99.10% - 99.37%
    Color and Shape:Solid
    Molecular weight:531.89

    Ref: TM-T8711

  • Ralfinamide mesylate
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    Ralfinamide mesylate

    CAS:
    <p>Ralfinamide mesylate (FCE-26742A (mesylate)) is an orally available Na+ channel blocker.</p>
    Formula:C18H23FN2O5S
    Purity:99.83%
    Color and Shape:Solid
    Molecular weight:398.45

    Ref: TM-T7547

  • Ajmaline
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    Ajmaline

    CAS:
    <p>Ajmaline, a class Ia anti-arrhythmic, diagnoses Brugada syndrome and treats tachycardia; inhibits cardiac Kv1.5/Kv4.3 channels.</p>
    Formula:C20H26N2O2
    Purity:99.67% - 99.87%
    Color and Shape:Solid
    Molecular weight:326.43

    Ref: TM-T4550

  • ICA-121431
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    ICA-121431

    CAS:
    <p>ICA-121431: a potent Nav1.7 inhibitor (IC50=19 nM for rat), minimal effect on human Nav1.5/Nav1.7.</p>
    Formula:C23H19N3O3S2
    Purity:98.06%
    Color and Shape:Solid
    Molecular weight:449.55

    Ref: TM-T7336

  • (+)-Kavain
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    (+)-Kavain

    CAS:
    <p>(+)-Kavain ((R)-KAWAIN) is one of the six major kavalactones found in the Piper methysticum (kava) plant; reversible inhibitor of MAO-B.</p>
    Formula:C14H14O3
    Purity:97% - ≥95%
    Color and Shape:White Fine Powder
    Molecular weight:230.26

    Ref: TM-T4590

  • Benzamil
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    Benzamil

    CAS:
    <p>Benzamil blocks ENaC, inhibiting sodium transport (IC50=4 nM) and binds with Kd=5 nM to bovine kidney membranes.</p>
    Formula:C13H14ClN7O
    Purity:99.79%
    Color and Shape:Solid
    Molecular weight:319.75

    Ref: TM-T5850

  • 20(S)-Ginsenoside Rg3
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    20(S)-Ginsenoside Rg3

    CAS:
    <p>20(S)-Ginsenoside Rg3 (Rg3) possess an ability to inhibit the lung metastasis of tumor cells via inhibition of the adhesion and invasion of tumor cells.</p>
    Formula:C42H72O13
    Purity:98.11% - 99.93%
    Color and Shape:Solid
    Molecular weight:785.01

    Ref: TM-T3402

  • Dronedarone
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    Dronedarone

    CAS:
    <p>Dronedarone (SR 33589) is an amiodarone analogue which has an effective and promising treatment for Atrial fibrillation.</p>
    Formula:C31H44N2O5S
    Purity:98.85% - 99.58%
    Color and Shape:Solid
    Molecular weight:556.76

    Ref: TM-T7056

  • Evenamide
    Targetmol
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    Evenamide

    CAS:
    <p>Evenamide (NW-3509) is a sodium channel blocker. Which shows efficacy in a broad spectrum of rodent models of psychosis, mania, depression, and aggressiveness.</p>
    Formula:C16H26N2O2
    Purity:96.74% - 99.15%
    Color and Shape:Solid
    Molecular weight:278.39

    Ref: TM-T15260