Sodium Channel
Sodium channels are essential membrane proteins that allow the passage of sodium ions (Na+) across the cell membrane, generating and propagating electrical signals in neurons, muscle cells, and other excitable tissues. These channels are vital for the initiation and conduction of action potentials, making them crucial in processes such as nerve impulse transmission, muscle contraction, and cardiac function. Dysregulation of sodium channels can lead to neurological disorders, arrhythmias, and chronic pain conditions. At CymitQuimica, we provide a variety of sodium channel modulators to support your research in neurobiology, cardiology, and pain management.
Found 257 products of "Sodium Channel"
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Phrixotoxin 3
CAS:Potent NaV blocker: IC50 - 0.6 nM (NaV1.2), 42 nM (NaV1.3), 72 nM (NaV1.5); voltage-dependent inhibition.Formula:C176H269N51O48S6Purity:98%Color and Shape:SolidMolecular weight:4059.74Halazone
CAS:Halazone (Pantocid) is fine white powder with an odor of chlorine. It has been widely used to disinfect drinking water.Formula:C7H5Cl2NO4SPurity:98.64%Color and Shape:Physical Description Fine White Powder With An Odor Of Chlorine (Ntp 1992)Molecular weight:270.09µ-Conotoxin BuIIIC
CAS:μ-Conotoxin BuIIIC (Mu-Conotoxin BuIIIC) effectively inhibits the NaV1.4 sodium channel [1].Formula:C116H189N49O34S6Purity:98%Color and Shape:SolidMolecular weight:3006.44µ-Conotoxin-CnIIIC
CAS:μ-Conotoxin-CnIIIC, a 22-residue conopeptide derived from Conus consors, acts as a potent and persistent NaV1.4 channel blocker, exhibiting analgesic,Formula:C92H139N35O28S6Purity:98%Color and Shape:SolidMolecular weight:2375.7Jingzhaotoxin-V
Jingzhaotoxin-V, a 29-residue polypeptide from Chilobrachys jingzhao spider venom, selectively inhibits tetrodotoxin-resistant and tetrodotoxin-sensitive sodiumFormula:C157H243N47O37S7Purity:98%Color and Shape:SolidMolecular weight:3605.36μ-Conotoxin SxIIIC
μ-Conotoxin SxIIIC, an irreversible NaV channel inhibitor, is derived from Conus striolatus and is useful in researching neurological disorders, includingFormula:C90H142N42O27S6Purity:98%Color and Shape:SolidMolecular weight:2436.75Sodium Channel Targeted Library
A unique collection of xnum sodium channel blockers and agonists for high throughput and high content screening;Color and Shape:Odour SolidRef: TM-L7400
1mgTo inquire30μL*10mM (DMSO)To inquire50μL*10mM (DMSO)To inquire100μL*10mM (DMSO)To inquire250μL*10mM (DMSO)To inquireLifarizine FA
Lifarizine FA is a sodium channel blocker used in the treatment of neurological disorders and cardiovascular diseases, study of stroke.Formula:C30H34N4O2Purity:99.55%Color and Shape:SolidMolecular weight:482.62µ-Conotoxin-CnIIIC acetate
µ-Conotoxin-CnIIIC acetate is a NaV1.4 sodium channel antagonist, a conotoxin peptide consisting of 22 amino acids, used for muscle relaxation and pain relief.Formula:C92H139N35O28S6·xC2H4O2Purity:99.94%Color and Shape:SolidMolecular weight:2375.70 (free base)GX 201
CAS:GX 201 is a selective NaV1.7 inhibitor, IC50 of < 3.2 nM for hNaV1.7.Formula:C25H27ClF4N2O4SPurity:99.81%Color and Shape:SolidMolecular weight:563Hainantoxin-III
CAS:Jingzhaotoxin-V is a peptide that suppresses potassium currents in Xenopus laevis oocytes, exhibiting an IC50 of 604.2 nM, while concurrently targeting bothFormula:C154H228N44O45S6Purity:98%Color and Shape:SolidMolecular weight:3608.12µ-Conotoxin BuIIIB
CAS:μ-Conotoxin BuIIIB (Mu-Conotoxin BuIIIB), a selective blocker of mammalian neuronal voltage-gated sodium channels (VGSC), is derived from Cone snail venom andFormula:C106H172N46O30S6Purity:98%Color and Shape:SolidMolecular weight:2763.18GpTx-1 TFA
GpTx-1 TFA is a polypeptide NaV1.7 sodium channel antagonist isolated from the venom of the Chilean spider Grammostola porter. It exhibits potent inhibitory activity on the NaV1.7 channel with an IC50 value of 10 nM, demonstrating excellent selectivity over NaV1.4 (IC50 = 0.301 μM) and NaV1.5 (IC50 = 4.20 μM) with >20-fold and >950-fold selectivity, respectively.Color and Shape:Odour SolidPhlotoxin-1
Phlotoxin-1 (PhlTx1), a 34-amino acid peptide featuring three disulfide bridges, is derived from the Phlogiellus genus spider and acts as an antinociceptiveFormula:C183H254N46O48S6Purity:98%Color and Shape:SolidMolecular weight:4058.64Veratridine
CAS:Veratridine is a benzoate-cevane found in Veratrum and Schoenocaulon. It activates sodium channels to stay open longer than normal.Formula:C36H51NO11Purity:98.07% - 99.27%Color and Shape:Yellowish-White Amorphous Powder PowderMolecular weight:673.79δ-Buthitoxin-Hj2a
δ-Buthitoxin-Hj2a, a potent scorpion-venom peptide, acts as a NaV1.1 agonist with an EC50 value of 32 nM and is employed in Dravet syndrome (DS) research [1].Formula:C304H458N90O93S8Purity:98%Color and Shape:SolidMolecular weight:7117.96BDS-II
BDS-II, a peptide toxin comprising 43 amino acids, selectively inhibits the Kv3.4 channel [1].Formula:C214H301N57O57S6Purity:98%Color and Shape:SolidMolecular weight:4776.42Analgesic agent-2
Analgesic Agent-2, a selective orally active inhibitor of the NaV1.8 channel, demonstrates an IC50 of 50.18 nM in HEK293 cells that stably express the humanFormula:C21H21ClF2N4O2Purity:98%Color and Shape:SolidMolecular weight:434.87Mexiletine-d6 hydrochloride
CAS:Mexiletine D6 hydrochloride is a non-selective voltage-gated sodium channel blocker,is a Class IB antianhythmic.Formula:C11H18ClNOPurity:98%Color and Shape:SolidMolecular weight:221.76Bulleyaconitine A
CAS:Bulleyaconitine A, an analgesic and antiinflammatory drug isolated from Aconitum plants, has several potential targets, such as voltage-gated Na+ channels.Formula:C35H49NO9Purity:99.56% - 99.76%Color and Shape:SolidMolecular weight:627.76
