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Sodium Channel

Sodium Channel

Sodium channels are essential membrane proteins that allow the passage of sodium ions (Na+) across the cell membrane, generating and propagating electrical signals in neurons, muscle cells, and other excitable tissues. These channels are vital for the initiation and conduction of action potentials, making them crucial in processes such as nerve impulse transmission, muscle contraction, and cardiac function. Dysregulation of sodium channels can lead to neurological disorders, arrhythmias, and chronic pain conditions. At CymitQuimica, we provide a variety of sodium channel modulators to support your research in neurobiology, cardiology, and pain management.

Found 202 products of "Sodium Channel"

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  • E 0747

    CAS:
    <p>E 0747 is an antiarrhythmic agent of class 1C type. E-0747 suppresses arrhythmia by inhibiting the Na channels of cardiac cells.</p>
    Formula:C21H28ClN3O4
    Purity:95.17%
    Color and Shape:Solid
    Molecular weight:421.92
  • GX-674

    CAS:
    <p>GX-674 is a highly potent and selective voltage-gated sodium channel 1.7 (Nav1.7) antagonist with an IC50 value of 0.1 nM measured at -40 mV for the study of</p>
    Formula:C21H13ClF2N6O3S2
    Purity:98.60%
    Color and Shape:Solid
    Molecular weight:534.95
  • DPI 201-106

    CAS:
    <p>DPI 201-106: cardioselective h1 Na channel inhibitor, enhances heart contraction, blocks potassium and calcium currents.</p>
    Formula:C29H30N4O2
    Purity:99.94%
    Color and Shape:Solid
    Molecular weight:466.57
  • PF 05089771 tosylate

    CAS:
    <p>PF-05089771 inhibits Nav1.7 channels (IC50: 11-33 nM), selective over Nav1.1-1.6/1.8, Ca+, K+ channels, TRPV1; 1000x affinity for half-inactivated state.</p>
    Formula:C18H12Cl2FN5O3S2·C7H8O3S
    Purity:98.55%
    Color and Shape:Solid
    Molecular weight:672.56
  • NHE3-IN-2

    CAS:
    <p>NHE3-IN-2 is an inhibitor of NHE3 (Na+/H+ exchanger-3), applicable for treating hypertension, thrombosis, and ischaemic diseases.</p>
    Formula:C15H12ClN5
    Color and Shape:Solid
    Molecular weight:297.74
  • Halofuginone hydrobromide

    CAS:
    <p>Halofuginone specifically inhibits collagen type I and MMP-2 gene expression, which may result in the suppression of angiogenesis and tumor cell growth.</p>
    Formula:C16H17BrClN3O3·HBr
    Purity:97.01% - 99.73%
    Color and Shape:Solid
    Molecular weight:495.59
  • Phenamil

    CAS:
    <p>Phenamil is an inhibitor of epithelial sodium channels, activates the osteomorphin protein pathway to promote bone repair and induces significant fat formation.</p>
    Formula:C12H12ClN7O
    Purity:99.07%
    Color and Shape:Solid
    Molecular weight:305.72
  • GDC-0276

    CAS:
    <p>GDC-0276 is an orally active, selective, and potent NaV1.7 inhibitor that can be used for the study of pain-related diseases.</p>
    Formula:C24H31FN2O4S
    Purity:99.77%
    Color and Shape:Solid
    Molecular weight:462.58
  • KR-32568

    CAS:
    <p>KR-32568 is a sodium/hydrogen exchanger 1 (NHE-1) inhibitor (IC50: 230 nM).</p>
    Formula:C13H12FN3O2
    Purity:99.91%
    Color and Shape:Solid
    Molecular weight:261.25
  • Nisoxetine hydrochloride

    CAS:
    <p>Nisoxetine hydrochloride is a noradrenaline transporter (NET) inhibitor</p>
    Formula:C17H21NO2·HCl
    Purity:99.21%
    Color and Shape:White Solid
    Molecular weight:307.82
  • Silperisone HCl

    CAS:
    <p>Silperisone HCl is a muscle relaxant and vasodilator, treating myoclonus, hypertonia, dystonia, and myospasm by blocking Na+ and Ca2+ channels.</p>
    Formula:C15H25ClFNSi
    Purity:99.62%
    Color and Shape:Solid
    Molecular weight:301.9
  • Elpetrigine

    CAS:
    <p>Elpetrigine (GW273293) is a potential sodium channel blocker with antiepileptic activity that can be used to study epilepsy.</p>
    Formula:C10H7Cl3N4
    Purity:99.04% - 99.43%
    Color and Shape:Solid
    Molecular weight:289.55
  • NaV1.2/1.6 channel blocker-1

    CAS:
    <p>NaV1.2/1.6 channel blocker-1 is a NaV1.2/1.6 channel blocker that inhibits rNaV1.6 and can be used to study generalised epilepsy and movement disorders.</p>
    Formula:C14H14N2OS
    Purity:99.54%
    Color and Shape:Solid
    Molecular weight:258.34
  • NHE3-IN-1

    CAS:
    <p>NHE3-IN-1 是钠/质子交换剂 3 (NHE-3) 的抑制剂。</p>
    Formula:C12H10ClN3S
    Purity:99.93%
    Color and Shape:Solid
    Molecular weight:263.75
  • TC-N 1752

    CAS:
    <p>TC-N 1752 is an orally active inhibitor of Nav1.7 channel with IC50 of 0.17 μM. TC-N 1752 shows analgesic activities.</p>
    Formula:C25H27F3N6O3
    Purity:99.71%
    Color and Shape:Solid
    Molecular weight:516.52
  • Ralitoline

    CAS:
    <p>Ralitoline (Ralitolinum) is an anticonvulsant with anticancer activity and sodium channel blocking activity.</p>
    Formula:C13H13ClN2O2S
    Purity:98.45%
    Color and Shape:Solid
    Molecular weight:296.77
  • (Rac)-AMG8379

    CAS:
    <p>(Rac)-AMG8379 ((Rac)-AMG8380) is a racemate of AMG8379 which is an orally active and selective sulfonamide NaV1.7 antagonist.</p>
    Formula:C25H16ClF2N3O5S
    Purity:99.6%
    Color and Shape:Solid
    Molecular weight:543.93
  • SLC13A5-IN-1

    CAS:
    <p>SLC13A5-IN-1 is a selective inhibitor of sodium-citrate co-transporter (SLC13A5),completely blocks the uptake of 14C-citrate(IC50 : 0.022 μM in HepG2 cells).</p>
    Formula:C19H19Cl3N2O3S
    Purity:99.67%
    Color and Shape:Solid
    Molecular weight:461.79
  • PF 04531083

    CAS:
    <p>PF 04531083 is a selective blocker of the NaV1.8 channel. PF 04531083 can be used for neuropathic and inflammatory pain studies.</p>
    Formula:C17H16ClN5O2
    Purity:99.85%
    Color and Shape:Solid
    Molecular weight:357.79
  • Aneratrigine

    CAS:
    <p>Aneratrigine is a blocker of the sodium channel protein type 9 subunit alpha, utilized in research on neuropathic pain diseases [1].</p>
    Formula:C19H20ClF2N5O2S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:487.97