
Sodium Channel
Sodium channels are essential membrane proteins that allow the passage of sodium ions (Na+) across the cell membrane, generating and propagating electrical signals in neurons, muscle cells, and other excitable tissues. These channels are vital for the initiation and conduction of action potentials, making them crucial in processes such as nerve impulse transmission, muscle contraction, and cardiac function. Dysregulation of sodium channels can lead to neurological disorders, arrhythmias, and chronic pain conditions. At CymitQuimica, we provide a variety of sodium channel modulators to support your research in neurobiology, cardiology, and pain management.
Found 202 products of "Sodium Channel"
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E 0747
CAS:<p>E 0747 is an antiarrhythmic agent of class 1C type. E-0747 suppresses arrhythmia by inhibiting the Na channels of cardiac cells.</p>Formula:C21H28ClN3O4Purity:95.17%Color and Shape:SolidMolecular weight:421.92GX-674
CAS:<p>GX-674 is a highly potent and selective voltage-gated sodium channel 1.7 (Nav1.7) antagonist with an IC50 value of 0.1 nM measured at -40 mV for the study of</p>Formula:C21H13ClF2N6O3S2Purity:98.60%Color and Shape:SolidMolecular weight:534.95DPI 201-106
CAS:<p>DPI 201-106: cardioselective h1 Na channel inhibitor, enhances heart contraction, blocks potassium and calcium currents.</p>Formula:C29H30N4O2Purity:99.94%Color and Shape:SolidMolecular weight:466.57PF 05089771 tosylate
CAS:<p>PF-05089771 inhibits Nav1.7 channels (IC50: 11-33 nM), selective over Nav1.1-1.6/1.8, Ca+, K+ channels, TRPV1; 1000x affinity for half-inactivated state.</p>Formula:C18H12Cl2FN5O3S2·C7H8O3SPurity:98.55%Color and Shape:SolidMolecular weight:672.56NHE3-IN-2
CAS:<p>NHE3-IN-2 is an inhibitor of NHE3 (Na+/H+ exchanger-3), applicable for treating hypertension, thrombosis, and ischaemic diseases.</p>Formula:C15H12ClN5Color and Shape:SolidMolecular weight:297.74Halofuginone hydrobromide
CAS:<p>Halofuginone specifically inhibits collagen type I and MMP-2 gene expression, which may result in the suppression of angiogenesis and tumor cell growth.</p>Formula:C16H17BrClN3O3·HBrPurity:97.01% - 99.73%Color and Shape:SolidMolecular weight:495.59Phenamil
CAS:<p>Phenamil is an inhibitor of epithelial sodium channels, activates the osteomorphin protein pathway to promote bone repair and induces significant fat formation.</p>Formula:C12H12ClN7OPurity:99.07%Color and Shape:SolidMolecular weight:305.72GDC-0276
CAS:<p>GDC-0276 is an orally active, selective, and potent NaV1.7 inhibitor that can be used for the study of pain-related diseases.</p>Formula:C24H31FN2O4SPurity:99.77%Color and Shape:SolidMolecular weight:462.58KR-32568
CAS:<p>KR-32568 is a sodium/hydrogen exchanger 1 (NHE-1) inhibitor (IC50: 230 nM).</p>Formula:C13H12FN3O2Purity:99.91%Color and Shape:SolidMolecular weight:261.25Nisoxetine hydrochloride
CAS:<p>Nisoxetine hydrochloride is a noradrenaline transporter (NET) inhibitor</p>Formula:C17H21NO2·HClPurity:99.21%Color and Shape:White SolidMolecular weight:307.82Silperisone HCl
CAS:<p>Silperisone HCl is a muscle relaxant and vasodilator, treating myoclonus, hypertonia, dystonia, and myospasm by blocking Na+ and Ca2+ channels.</p>Formula:C15H25ClFNSiPurity:99.62%Color and Shape:SolidMolecular weight:301.9Elpetrigine
CAS:<p>Elpetrigine (GW273293) is a potential sodium channel blocker with antiepileptic activity that can be used to study epilepsy.</p>Formula:C10H7Cl3N4Purity:99.04% - 99.43%Color and Shape:SolidMolecular weight:289.55NaV1.2/1.6 channel blocker-1
CAS:<p>NaV1.2/1.6 channel blocker-1 is a NaV1.2/1.6 channel blocker that inhibits rNaV1.6 and can be used to study generalised epilepsy and movement disorders.</p>Formula:C14H14N2OSPurity:99.54%Color and Shape:SolidMolecular weight:258.34NHE3-IN-1
CAS:<p>NHE3-IN-1 是钠/质子交换剂 3 (NHE-3) 的抑制剂。</p>Formula:C12H10ClN3SPurity:99.93%Color and Shape:SolidMolecular weight:263.75TC-N 1752
CAS:<p>TC-N 1752 is an orally active inhibitor of Nav1.7 channel with IC50 of 0.17 μM. TC-N 1752 shows analgesic activities.</p>Formula:C25H27F3N6O3Purity:99.71%Color and Shape:SolidMolecular weight:516.52Ralitoline
CAS:<p>Ralitoline (Ralitolinum) is an anticonvulsant with anticancer activity and sodium channel blocking activity.</p>Formula:C13H13ClN2O2SPurity:98.45%Color and Shape:SolidMolecular weight:296.77(Rac)-AMG8379
CAS:<p>(Rac)-AMG8379 ((Rac)-AMG8380) is a racemate of AMG8379 which is an orally active and selective sulfonamide NaV1.7 antagonist.</p>Formula:C25H16ClF2N3O5SPurity:99.6%Color and Shape:SolidMolecular weight:543.93SLC13A5-IN-1
CAS:<p>SLC13A5-IN-1 is a selective inhibitor of sodium-citrate co-transporter (SLC13A5),completely blocks the uptake of 14C-citrate(IC50 : 0.022 μM in HepG2 cells).</p>Formula:C19H19Cl3N2O3SPurity:99.67%Color and Shape:SolidMolecular weight:461.79PF 04531083
CAS:<p>PF 04531083 is a selective blocker of the NaV1.8 channel. PF 04531083 can be used for neuropathic and inflammatory pain studies.</p>Formula:C17H16ClN5O2Purity:99.85%Color and Shape:SolidMolecular weight:357.79Aneratrigine
CAS:<p>Aneratrigine is a blocker of the sodium channel protein type 9 subunit alpha, utilized in research on neuropathic pain diseases [1].</p>Formula:C19H20ClF2N5O2S2Purity:98%Color and Shape:SolidMolecular weight:487.97
