Calcium Channel
Calcium channels are membrane proteins that regulate the flow of calcium ions into and out of cells, which is essential for various cellular functions, including muscle contraction, neurotransmitter release, and gene expression. Dysregulation of calcium channel activity is associated with conditions such as hypertension, cardiac arrhythmias, and neurological disorders. At CymitQuimica, we provide a wide selection of calcium channel modulators to support your research in cardiovascular health, neurobiology, and signal transduction.
Found 493 products of "Calcium Channel"
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1-(aminomethyl)cyclopropanecarboxylic acid hydrochloride
CAS:<p>1-(aminomethyl)cyclopropanecarboxylic acid hydrochloride inhibits L amino acid transporter proteins and the α2δ subunit of voltage-gated calcium channels.1-(</p>Formula:C5H10ClNO2Purity:>99.99%Color and Shape:SolidMolecular weight:151.59Calcium Channel antagonist 2
CAS:<p>Calcium Channel antagonist 2 is a calcium channel antagonist (IC50=5-20 μM) that can be used to study diseases due to Ca2+ channels like pain and diabetes.</p>Formula:C23H25FN2O4SPurity:99.34%Color and Shape:SolidMolecular weight:444.52Lyso-Globotriaosylceramide (d18:1)
CAS:<p>Lyso-Gb3, lacking fatty acyl, binds Stx1 with cholesterol and phosphatidylcholine, not Stx2; lowers neutrophil viability; accumulates in Fabry disease.</p>Formula:C36H67NO17Color and Shape:SolidMolecular weight:785.922Calcium Channel Compound Library
<p>A unique collection of 140 calcium channel blockers and agonists for high throughput and high content screening;</p>Color and Shape:Odour SolidLY393615
<p>LY393615 (NCC1048) is a novel blocker of both neuronal Ca²⁺ (calcium) and Na⁺ (sodium) channels, exhibiting half-maximal inhibitory concentrations (IC₅₀) of 1.9</p>Purity:98%Color and Shape:Odour Solidγ-Glutamylserine TFA
<p>γ-Glutamylserine TFA (γ-Glu-Ser TFA) serves as a calcium receptor activator and is utilized in research focused on Parkinson's disease, diabetes, and obesity [1</p>Formula:C10H15F3N2O8Purity:98%Color and Shape:SoildMolecular weight:348.23Calcium Channel antagonist 5
CAS:<p>Calcium Channel antagonist5 (compound 32) is a calcium channel antagonist with a pIC50 of 5.50.</p>Formula:C17H18N2O6Color and Shape:SolidMolecular weight:346.34ω-Agatoxin IVA
CAS:<p>Selective blocker of P-type calcium channels (IC50 < 1 - 3 nM). Also inhibits N-type channels at micromolar concentrations.</p>Formula:C217H360N68O60S10Purity:98%Color and Shape:SolidMolecular weight:5202.25Oxodipine
CAS:<p>Oxodipine blocks rabbit aortic contraction and weakens rat cardiac force; reduces Ca currents in myocytes; side effects: mouse constipation, dog gum swelling.</p>Formula:C19H21NO6Purity:99.24%Color and Shape:SolidMolecular weight:359.372-Nitrobenzoic acid
CAS:<p>2-Nitrobenzoic acid is an anti-growth agent with an IC50 of 8.3 μM against Jurkat cells with T-type Ca²⁺ channel alpha 1H/delta 25.</p>Formula:C7H5NO4Purity:99.97%Color and Shape:SoildMolecular weight:167.12Flosatidil
CAS:<p>Flosatidil is a small molecule voltage-gated calcium channel complex (VDCCs) blocker for the treatment of neurological disorders and cardiovascular diseases,</p>Formula:C26H34F3N3O3SPurity:98.29% - 99.60%Color and Shape:SolidMolecular weight:525.63Candidalysin
CAS:<p>Candidalysin is a cytolytic peptide toxin initially isolated from *Candida albicans*, exhibiting both toxic and non-toxic properties. It activates epithelial cell signaling pathways by interacting with the epithelial growth factor receptor (EGFR) on host cells, leading to the activation of matrix metalloproteinases (MMP) and calcium ion influx, which results in inflammatory responses and immune cell recruitment. Additionally, Candidalysin exhibits cytotoxicity by causing membrane damage to host cells.</p>Formula:C153H266N38O38S2Color and Shape:SolidMolecular weight:3310.11Ziconotide
CAS:<p>Ziconotide: analgesic from cone snail for severe, chronic pain; synthetic ω-conotoxin.</p>Formula:C102H172N36O32S7Purity:98%Color and Shape:White PowderMolecular weight:2639.13Calcium Ionophore I
CAS:<p>Calcium Ionophore I has a wide range of applications in life science related research.</p>Formula:C38H72N2O8Color and Shape:SolidMolecular weight:685.0O-Desmethylcarvedilol
CAS:<p>O-Desmethylcarvedilol (Desmethylcarvedilol) is an active metabolite of Carvedilol, a non-selective β-adrenergic receptor (β-AR) antagonist. This compound inhibits store overload-induced calcium release in HEK293 cells expressing the RyR2 R4496C mutation (IC50= 7.62 µM). Additionally, O-Desmethylcarvedilol slows the increase in heart rate and prevents diastolic pressure reduction induced by Isoproterenol in conscious rabbits (ED50s = 32 and 5 µg/kg).</p>Formula:C23H24N2O4Color and Shape:SolidMolecular weight:392.45ω-Conotoxin GVIA
CAS:<p>Peptide neurotoxin; selectively and reversibly blocks N-type calcium channels (IC50 = 0.15 nM). Reduces (RS)-3,5-DHPG -induced long term depression in vivo.</p>Formula:C120H182N38O43S6Purity:98%Color and Shape:SolidMolecular weight:3037Ryanodine
CAS:<p>Ryanodine: a diterpenoid modulating Ca2+ release via ryanodine receptors; concentration-dependent effects; found in Ryania speciosa; toxic.</p>Formula:C25H35NO9Purity:98%Color and Shape:White SolidMolecular weight:493.553SNX-482
CAS:<p>Potent CaV2.3 calcium channel blocker, selective, voltage-dependent, with 30 nM IC50. Offers antinociceptive effects on C and Aδ fibres.</p>Formula:C192H274N52O60S7Purity:98%Color and Shape:SolidMolecular weight:4495.01Mast cell degranulating peptide (28-49)
CAS:<p>Mast cell degranulating peptide (28-49) is a bee venom depolarizer that can improve the cGMP content of cerebellum tablets in mice.</p>Formula:C110H196N40O24S4Purity:98%Color and Shape:SolidMolecular weight:2591.25G-Glu-Ser
CAS:<p>G-Glu-Ser is a calcium receptor activator and Flavor-enriching agent.</p>Formula:C8H14N2O6Color and Shape:SolidMolecular weight:234.21Levamlodipine besylate Hemipentahydrate
CAS:<p>Levamlodipine besylate hemipentahydrate is the besylate hemipentahydrate salt form of Levamlodipine. It is an orally effective calcium channel blocker with antioxidative and vasodilatory properties. This compound can reduce serum malondialdehyde (MDA) levels, enhance the activity of superoxide dismutase (SOD), and alleviate oxidative stress. Levamlodipine besylate hemipentahydrate is relevant for research in vascular dementia, hypertension, and cerebrovascular diseases.</p>Formula:C20H25ClN2O5·C6H6O3SH2OColor and Shape:SolidMolecular weight:1224.18NSC156529
CAS:<p>NSC156529 suppresses AKT1, reduces cancer cell growth in vitro, and inhibits prostate tumors in vivo.</p>Formula:C28H21ClS2Purity:98%Color and Shape:SolidMolecular weight:457.05D-myo-Inositol-1,3-diphosphate (sodium salt)
CAS:<p>D-myo-Inositol-1,3-phosphate (Ins(1,3)P) is an inositol phosphate involved in cellular signal transduction.</p>Formula:C6H12Na2O12P2Color and Shape:SolidMolecular weight:384.08Mipsagargin
CAS:<p>Mipsagargin (G-202) is a new antibiotic that inhibits DNA biosynthesis.</p>Formula:C66H100N6O27Purity:98%Color and Shape:SolidMolecular weight:1409.52NAADP tetrasodium salt
CAS:<p>Ca2+ mobilizing agent</p>Formula:C21H27N6O18P3Purity:98%Color and Shape:SolidMolecular weight:744.39GTx1-15
<p>GTx1-15, an inhibitor cystine knot (ICK) peptide, antagonizes the voltage-dependent calcium channel Cav3.1, as well as voltage-dependent sodium channels Nav1.3</p>Formula:C176H271N53O45S7Purity:98%Color and Shape:SolidMolecular weight:4073.82Ins(1,4,5)-P3 hexapotassium salt
CAS:<p>D-myo-Inositol 1,4,5-trisphosphate hexapotassium salt is promotes endoplasmic The second messenger of net calcium ions.</p>Formula:C6H9K6O15P3Purity:98%Color and Shape:SolidMolecular weight:648.64Triphenylethylene
CAS:<p>Compound PDK0283, with CAS No. 58-72-0, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0283 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>Formula:C20H16Color and Shape:White PowderMolecular weight:256.34ProTx-I
CAS:<p>Selective blocker for CaV3.1 (IC50 = 0.2 μM), CaV3.2 (31.8 μM), also inhibits NaV1.8 and blocks KV2.1 channels.</p>Formula:C171H245N53O47S6Purity:98%Color and Shape:SolidMolecular weight:3987.51BTT-266
CAS:<p>BTT-266 is a blocker of voltage-gated calcium channel for pain management.</p>Formula:C34H28N4O4Purity:98.34%Color and Shape:SolidMolecular weight:556.61D-myo-Inositol-1,3,4,5-tetraphosphate (sodium salt)
CAS:<p>Ins(1,3,4,5)-P4, made via Ins(1,4,5)P3 phosphorylation, boosts calcium by opening ER and plasma membrane channels.</p>Formula:C6H8Na8O18P4Color and Shape:SolidMolecular weight:675.93Elgodipine
CAS:<p>Elgodipine decreases angina severity, inhibits muscle growth, and is voltage-sensitive, showing promise for angina treatment.</p>Formula:C29H33FN2O6Purity:98.95% - 99.50%Color and Shape:SolidMolecular weight:524.58Calcium Channel antagonist 3
CAS:<p>Calcium Channel antagonist 3 is a voltage-gated calcium channel inhibitor (IC50 : 5-20 μM).</p>Formula:C23H26N2O4SPurity:>99.99%Color and Shape:SolidMolecular weight:426.53D-myo-Inositol-1,4,5-triphosphate trisodium
CAS:<p>D-myo-Inositol-1,4,5-triphosphate trisodium (Inositol 1,4,5-trisphosphate trisodium) is a second messenger produced in cells by phospholipase C-mediated</p>Formula:C6H15Na3O15P3Purity:98%Color and Shape:SolidMolecular weight:489.06SB-237376
CAS:<p>SB-237376 is a calcium and potassium channel antagonist used to treat cardiac arrhythmias.</p>Formula:C20H25N3O5Purity:98.88% - 99.81%Color and Shape:SoildMolecular weight:387.43Ethyl 4-chloro-2-oxo-1,2-dihydroquinoline-3-carboxylate
CAS:<p>ethyl 4-chloro-2-oxo-1,2-dihydroquinoline-3-carboxylate inhibits NAD(P)H: quinone oxidoreductase 1.</p>Formula:C12H10ClNO3Purity:99.19%Color and Shape:SolidMolecular weight:251.67Chlorocresol
CAS:<p>Chlorocresol (4-Chloro-3-methylphenol) is an antiseptic medication.</p>Formula:C7H7ClOColor and Shape:SolidMolecular weight:142.58(±)5(6)-DiHETE
CAS:<p>Eicosapentaenoic acid is an ω-3 polyunsaturated fatty acid that is abundant in marine organisms and fish oils.</p>Formula:C20H32O4Color and Shape:SolidMolecular weight:336.472ω-Conotoxin MVIIC
CAS:<p>Peptide neurotoxin; wide spectrum blocker of N, P and Q type calcium channels.</p>Formula:C106H178N40O32S7Purity:98%Color and Shape:White Lyophilised SolidMolecular weight:2749ω-Agatoxin TK
CAS:<p>Selective blocker of CaV2.1 P/Q-type calcium channels.</p>Formula:C215H337N65O70S10Purity:98%Color and Shape:SolidMolecular weight:5273.02MRS1845
CAS:<p>MRS1845 is a selective inhibitor of store-operated calcium (SOC) channel (IC50 of 1.7 μM).</p>Formula:C21H22N2O6Purity:99.69%Color and Shape:SolidMolecular weight:398.41Almorexant hydrochloride
CAS:<p>Almorexant hydrochloride (ACT 078573 hydrochloride) is a dual orexin receptor antagonist that induces apoptosis and can be used to study sleep disorders.</p>Formula:C29H32ClF3N2O3Purity:99.85%Color and Shape:SolidMolecular weight:549.02YM-244769
CAS:<p>YM-244769 (3-Pyridinecarboxamide, N-[(3-aminophenyl)methyl]-6-[4-[(3-fluorophenyl)methoxy]phenoxy]-) is an effective inhibitor of Na+/Ca2+ exchange 3 (NCX3)</p>Formula:C26H22FN3O3Purity:95.62%Color and Shape:SolidMolecular weight:443.47YM-244769 dihydrochloride
CAS:<p>YM-244769 dihydrochloride is an effective inhibitor of Na+/Ca2+ exchange 3 (NCX3) with an IC50 of 18 nM.</p>Formula:C26H24Cl2FN3O3Purity:98%Color and Shape:SolidMolecular weight:516.39Nicardipine-d3 hydrochloride
CAS:<p>Nicardipine D3 hydrochloride is the deuterium labeled Nicardipine hydrochloride.</p>Formula:C26H30ClN3O6Purity:98%Color and Shape:SolidMolecular weight:519N-Palmitoyl Glycine
CAS:<p>Acyl amides like AEA modulate pain/inflammation. PalGly, similar to N-acyl ethanolamines, inhibits nociception and induces calcium influx in cells.</p>Formula:C18H35NO3Color and Shape:SolidMolecular weight:313.48(S)-Lercanidipine D3 hydrochloride
CAS:<p>(S)-Lercanidipine D3 hydrochloride is a deuterium labeled Lercanidipine D3 hydrochloride. (S)-Lercanidipine hydrochloride is an agent of antihypertensive.</p>Formula:C36H42ClN3O6Purity:98%Color and Shape:SolidMolecular weight:651.21(R)-Nicardipine
CAS:<p>(R)-Nicardipine is the less active R enantiomer of Nicardipine. Nicardipine is a blocker of calcium channel(IC50 of 1 μM for blocking cardiac calcium channels).</p>Formula:C26H29N3O6Color and Shape:SolidMolecular weight:479.53HSK16149
CAS:<p>HSK16149 is a novel ligand of voltage-gated calcium channel (VGCC) α 2 δ subunit with analgesic activity.</p>Formula:C12H19NO2Color and Shape:SolidMolecular weight:209.28Catharanthine
CAS:<p>Catharanthine ((+)-3,4-Didehydrocoronaridine) suppresses nicotinic receptor-mediated diaphragm contractions (IC50=59.6 μM).</p>Formula:C21H24N2O2Purity:99.11%Color and Shape:White PowderMolecular weight:336.43
