Calcium Channel
Calcium channels are membrane proteins that regulate the flow of calcium ions into and out of cells, which is essential for various cellular functions, including muscle contraction, neurotransmitter release, and gene expression. Dysregulation of calcium channel activity is associated with conditions such as hypertension, cardiac arrhythmias, and neurological disorders. At CymitQuimica, we provide a wide selection of calcium channel modulators to support your research in cardiovascular health, neurobiology, and signal transduction.
Found 573 products of "Calcium Channel"
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Nicardipine
CAS:Nicardipine (Cardene), a calcium channel blockers belonging to the dihydropyridine class, is a drug used to treat angina and high blood pressure.Formula:C26H29N3O6Purity:99.56%Color and Shape:SolidMolecular weight:479.52Zegocractin
CAS:Zegocractin (CM-4620) is a calcium-release activated calcium-channel (CRAC channel) inhibitor.Formula:C19H11ClF3N3O3Purity:98.82%Color and Shape:SolidMolecular weight:421.76Ref: TM-TQ0033
1mg119.00€5mg245.00€10mg409.00€25mg677.00€50mg945.00€100mg1,279.00€1mL*10mM (DMSO)268.00€MDK-4025
CAS:MDK-4025 is an inhibitor of the high voltage-activated (HVA) Ca2+ current in pyramidal neurons.Formula:C19H15ClOPurity:98.65%Color and Shape:SolidMolecular weight:294.77Bevantolol hydrochloride
CAS:Bevantolol hydrochloride (NC-1400 hydrochloride) is a β1-adrenoceptor antagonist that treatment angina pectoris and hypertension.Formula:C20H28ClNO4Purity:99.49%Color and Shape:SolidMolecular weight:381.9L-Ascorbic acid sodium salt
CAS:L-Ascorbic acid sodium salt (Vitamin C sodium salt) is a more bioavailable form of vitamin C that is an alternative to taking ascorbic acid as a supplement.Formula:C6H7NaO6Purity:98.73% - 99.75%Color and Shape:Less Solid PowderMolecular weight:198.11SN 6
CAS:SN 6 (SN6) is a selective Na+/Ca2+ exchanger (NCX) inhibitor (IC50s of NCX1: 2.9 μM , NCX2: 16 μM ,NCX3: 8.6 μM)Formula:C20H22N2O5SPurity:97.28%Color and Shape:SolidMolecular weight:402.46ZSET1446
CAS:ZSET1446 (ST-101) is a T-type calcium channel activator potentially for the treatment of learning deficits in various types of Alzheimer disease (AD) models.Formula:C15H12N2OPurity:99.32%Color and Shape:SolidMolecular weight:236.27Ref: TM-T8448
1mg50.00€5mg103.00€10mg144.00€25mg281.00€50mg409.00€100mg572.00€200mg772.00€1mL*10mM (DMSO)119.00€Menthol
CAS:Menthol (DL-Menthol) is an organic compound made synthetically or obtained from peppermint or mint oils with flavoring and local anesthetic properties.Formula:C10H20OPurity:99.84% - 99.88%Color and Shape:White Crystals /89-78-1/ Physical Description White Crystalline Solid With A Peppermint Odor And Taste (Ntp 1992)Molecular weight:156.2614-Deoxyandrographolide
CAS:14-Deoxyandrographolide is a bioactive compound of Andrographis paniculata with hepatoprotective efficacy.Formula:C20H30O4Purity:99.89% - 99.98%Color and Shape:SolidMolecular weight:334.45Cinacalcet metabolite M4
CAS:Cinacalcet metabolite M4 (Rarechem AL BW 1078) is a metabolite of Cinacalcet. Cinacalcet is an allosteric agonist of Ca receptor.Formula:C10H12F3NPurity:97.13%Color and Shape:SolidMolecular weight:203.2Ref: TM-T10814
5mg55.00€10mg74.00€25mg96.00€50mg137.00€100mg170.00€200mg244.00€500mg364.00€1mL*10mM (DMSO)51.00€Tetrandrine
CAS:Tetrandrine (Sinomenine A) is a naturally occurring biphenylisoquinoline alkaloid, a calcium channel inhibitor. Cost-effective and quality-assured.Formula:C38H42N2O6Purity:99.61% - 99.94%Color and Shape:White SolidMolecular weight:622.75HUP30
CAS:HUP30 is a potent vasodilating agent. HUP30 can stimulate soluble guanylyl cyclase, activate K+ channels, and block extracellular Ca2+ influx.Formula:C14H15N3O3SPurity:99.96%Color and Shape:SolidMolecular weight:305.35Ref: TM-TNU0864
5mg35.00€10mg52.00€25mg96.00€50mg156.00€100mg222.00€200mg310.00€1mL*10mM (DMSO)39.00€Apinocaltamide
CAS:Apinocaltamide (ACT-709478) is an orally available and selective T-type calcium channel blocker that cross BBB for Cav3.1, Cav3.2, and Cav3.3,epilepsy.Formula:C22H18F3N5OPurity:99.80%Color and Shape:SolidMolecular weight:425.41Bupivacaine
CAS:Bupivacaine (AH-250) is a NMDA receptor inhibitor.Bupivacaine can block sodium, L-calcium, and potassium channels.Bupivacaine potently blocks SCN5A channelsFormula:C18H28N2OPurity:99.83%Color and Shape:SolidMolecular weight:288.43Equilin
CAS:Equilin (7-Dehydroestrone) is a neurotrophic estrogenic steroid with vasodilatory activity used in the study of hypertension.Formula:C18H20O2Purity:98.57% - 99.72%Molecular weight:268.35Diltiazem
CAS:Diltiazem (CRD 401 free base) is an orally available L-type Ca2+ channel blocker with antihypertensive, antiarrhythmic, and cardioprotective properties that prevent post-reperfusion myocardial injury, angina pectoris, and cardiovascular-related diseases.Formula:C22H26N2O4SPurity:99.51% - 99.83%Color and Shape:White Crystalline Powder SolidMolecular weight:414.52Amlodipine maleate
CAS:Amlodipine maleate (Amvaz) is an oral dihydropyridine calcium blocker for hypertension and cancer studies.
Formula:C24H29ClN2O9Purity:99.4%Color and Shape:White To Pale Yellow Crystalline PowderMolecular weight:524.95Bupivacaine-d9
CAS:Bupivacaine-d9 is a deuterated compound of Bupivacaine. Bupivacaine has a CAS number of 38396-39-3. Bupivacaine is a NMDA receptor inhibitor.Bupivacaine can block sodium, L-calcium, and potassium channels.Bupivacaine potently blocks SCN5A channels with the IC50 of 69.5 μM. Bupivacaine can be used for the research of chronic pain.Formula:C18H19D9N2OColor and Shape:SolidMolecular weight:297.48Gabapentin enacarbil
CAS:Gabapentin enacarbil (XP-13512) is a prodrug for the anticonvulsant and analgesic gabapentin, offering sustained dose-proportional exposure and predictable bioavailability.Formula:C16H27NO6Purity:99.31%Color and Shape:SolidMolecular weight:329.39Ref: TM-T15366
1mg42.00€5mg88.00€10mg127.00€25mg274.00€50mg439.00€100mg705.00€200mg938.00€1mL*10mM (DMSO)87.00€4-(2-Chlorophenyl)-2-methyl-5-oxo-4,4a,5,7,8,10-hexahydro-1H-pyrido[2',3':2,3]azeto[2,1-c][1,4]oxazine-3-carboxylic Acid
Controlled ProductApplications 4-(2-Chlorophenyl)-2-methyl-5-oxo-4,4a,5,7,8,10-hexahydro-1H-pyrido[2',3':2,3]azeto[2,1-c][1,4]oxazine-3-carboxylic Acid is an intermediate in the synthesis of 3-O-Desethyl-5-O-desmethyl Amlodipine (D291305). 3-O-Desethyl-5-O-desmethyl Amlodipine is an impurity of Amlodipine (A633495), which is a dihydropyridine calcium channel blocker.
References Arrowsmith, J.E., et al.: J. Med. Chem., 29, 1696 (1986); Burges, R.A., et al.: J. Cardiovasc. Pharmacol., 9, 110 (1987); Haria, M., et al.: Drugs, 50, 560 (1995)Formula:C17H17ClN2O4Color and Shape:NeatMolecular weight:348.7811-tert-Butyl 3-Ethyl 5-methyl 2-((2-((tert-Butoxycarbonyl)amino)ethoxy)methyl)-4-(2-chlorophenyl)-6-methylpyridine-1,3,5(4H)-tricarboxylate
CAS:Controlled ProductApplications 1-tert-Butyl 3-Ethyl 5-methyl 2-((2-((tert-Butoxycarbonyl)amino)ethoxy)methyl)-4-(2-chlorophenyl)-6-methylpyridine-1,3,5(4H)-tricarboxylate is an intermediate in the synthesis of 3-O-Desethyl-5-O-desmethyl Amlodipine (D291305). 3-O-Desethyl-5-O-desmethyl Amlodipine is an impurity of Amlodipine (A633495), which is a dihydropyridine calcium channel blocker.
References Arrowsmith, J.E., et al.: J. Med. Chem., 29, 1696 (1986); Burges, R.A., et al.: J. Cardiovasc. Pharmacol., 9, 110 (1987); Haria, M., et al.: Drugs, 50, 560 (1995)Formula:C30H41ClN2O9Color and Shape:NeatMolecular weight:609.107Amlodipine besilate impurity G
CAS:Amlodipine besilate impurity G is a Calcium Channel antagonist with potential application in the study of neurological diseases and is an impurity in theFormula:C17H18ClNO4Purity:98%Color and Shape:SolidMolecular weight:335.78Amlodipine hydrochloride
CAS:Amlodipine hydrochloride is a salt of Amlodipine --- a medication used to lower blood pressure and prevent chest pain.Formula:C20H26Cl2N2O5Color and Shape:SolidMolecular weight:445.34Cinepazide
CAS:Cinepazide: a vasodilator targeting adenosine A2 receptors, treats various vascular diseases.Formula:C22H31N3O5Color and Shape:White PowderMolecular weight:417.5Topiramate D12
CAS:Topiramate D12 is a deuterium labeled Topiramate. Topiramate is an agent of broad-spectrum antiepileptic. Topiramate is an antagonist of GluR5 receptor.Formula:C12H21NO8SPurity:98%Color and Shape:SolidMolecular weight:351.44Nifedipine-d6
CAS:Nifedipine D6 is deuterium labeled nifedipine which is a potent blocker of calcium channel.
Formula:C17H18N2O6Purity:98%Color and Shape:SolidMolecular weight:352.37Maresin 1
CAS:Maresin 1 is biosynthesized by macrophages (MΦ) and possesses significant anti-inflammatory activity that attenuates LPS-induced lung injury in mice.Formula:C22H32O4Color and Shape:SolidMolecular weight:360.49Cinnarizine D8
CAS:Cinnarizine D8 is a deuterium-labeled Cinnarizine which is an antihistamine and a calcium channel blocker.Formula:C26H28N2Purity:98%Color and Shape:SolidMolecular weight:376.573Ionomycin calcium
CAS:Ionomycin calcium (SQ23377 calcium) is an effective and selective calcium ionophore, exhibiting high specificity for calcium ions. Cost-effective and quality-assured.
Formula:C41H70CaO9Purity:98% - 98.11%Color and Shape:SolidMolecular weight:747.07ORM-10103
CAS:ORM-10103 is a novel potent and selective inhibitor of the Na+/Ca2+ exchanger (NCX).ORM-10103 inhibited NCX currents with estimated IC50 values of 55 and 67 nMFormula:C20H16N2O4Purity:99.9%Color and Shape:SolidMolecular weight:348.35Ref: TM-T12321
1mg43.00€5mg90.00€10mg135.00€25mg278.00€50mg445.00€100mg605.00€200mg817.00€1mL*10mM (DMSO)90.00€R-(-)-Niguldipine hydrochloride
CAS:R-(-)-Niguldipine HCl: L-type Ca2+ blocker, K+ agonist, α1A antagonist; lowers blood pressure; weaker enantiomer.Formula:C36H40ClN3O6Color and Shape:SolidMolecular weight:646.17(R)-Lercanidipine Hydrochloride
CAS:Controlled ProductFormula:C36H41N3O6·ClHColor and Shape:NeatMolecular weight:648.19(S)-Lercanidipine Hydrochloride
CAS:Controlled ProductFormula:C36H41N3O6·ClHColor and Shape:NeatMolecular weight:648.19Dehydro Azelnidipine
CAS:Controlled ProductFormula:C33H32N4O6Color and Shape:Light Yellow To Light GreenMolecular weight:580.63Dihydrocinnamyl Cilnidipine
Controlled ProductApplications Dihydrocinnamyl Cilnidipine is a metabolite of Cilnidipine (C441375); a dihydropyridine calcium channel blocker.
References Ikeda, K., et al.: Oyo Yakuri, 44, 433 (1992); Hosono, M., et al.: J. Pharmacobio-Dyn., 15, 547, (1992); Ishii, M.: Japan Pharmacol. Ther., 21, 59 (1993)Formula:C27H30N2O7Color and Shape:NeatMolecular weight:494.54Falipamil
CAS:Controlled ProductApplications Falipamil is a specific bradycardic agent and a calcium channel blocker.
References Boucher, M., et al.: Eur. J. Pharmacol., 306, 93 (1996), Mubagwa, K., et al.: Arch. Int. Pharmacodyn. Ther., 286, 71 (1987), Chaudhry, A., et al.: Development Cardiovascular Medicine, 46, 196 (1985), Ogiwara, Y., et al.: Jpn Heart J., 29, (1988)Formula:C24H32N2O5Color and Shape:NeatMolecular weight:428.523-Desethyl-3-(2-phthalimidoethyl) Phthaloyl Amlodipine
Controlled ProductStability Light and Temperature Sensitive
Applications 3-Desethyl-3-(2-phthalimidoethyl) Phthaloyl Amlodipine is a derivative of Amlodipine (A633495); a dihydropyridine calcium channel blocker where activity mainly resides in the (-)-isomer.
References Arrowsmith, J.E., et al.: J. Med. Chem., 29, 1696 (1986); Burges, R.A., et al.: J. Cardiovasc. Pharmacol., 9, 110 (1987); Haria, M., et al.: Drugs, 50, 560 (1995)Formula:C36H30ClN3O9Color and Shape:NeatMolecular weight:684.091N-Desmethyl-N-acetyl Diltiazem
Controlled ProductApplications N-Desmethyl-N-acetyl Diltiazem is a metabolite of Diltiazem (D460620, HCl); a calcium channel blocker with vasodilating activity. Also anti-anginal, anti-hypertensive, and anti-arrhythmic (class IV).
References Sato, et al.: Arzneim.-Forsch., 21, 1338 (1971); Smirnov, S.R.: Eur. J. Pharmacol., 360, 81 (1998); Hansson, L., et al.: Lancet, 356, 359 (2000)Formula:C23H26N2O5SColor and Shape:NeatMolecular weight:442.53Halofuginone
CAS:Halofuginone (RU-19110) inhibits prolyl-tRNA synthetase (Ki=18.3 nM), down-regulates Smad3, and blocks TGF-β at 10 ng/ml.Formula:C16H17BrClN3O3Purity:99.53%Color and Shape:Off-White SolidMolecular weight:414.68Ref: TM-T6856
1mg34.00€5mg82.00€10mg116.00€25mg227.00€50mg344.00€100mg517.00€500mg1,134.00€1mL*10mM (DMSO)92.00€Verapamil
CAS:Verapamil (CP-16533-1), an oral calcium channel blocker, inhibits P-gp and CYP3A4, used for hypertension, arrhythmias, and angina research.Formula:C27H38N2O4Purity:99.61% - 99.93%Color and Shape:OilMolecular weight:454.6Ref: TM-T20656
10mg34.00€25mg49.00€50mg70.00€100mg90.00€200mg136.00€500mg219.00€1mL*10mM (DMSO)52.00€BA 41899
CAS:BA 41899 is a positive inotropic Ca(2+)-sensitizing agent.Formula:C18H16N2O2Color and Shape:SolidMolecular weight:292.33MRS2690
CAS:MRS2690 is a potent P2Y14 receptor agonist (EC50 = 49 nM) that displays 7-fold higher potency than UDP-glucose.Formula:C15H24N2O16P2SColor and Shape:SolidMolecular weight:582.37SIM-6080
CAS:SIM-6080 is a calcium channel antagonist. SIM-6080 inhibits the proliferation of rat aortic myocytes.Formula:C29H36F2N2O3Color and Shape:SolidMolecular weight:498.6RS-93522
CAS:RS-93522: Calcium channel antagonist, inhibits phosphodiesterase (IC50=1.6x10^-5M), like milrinone, and has a negative inotropic effect.Formula:C27H30N2O9Purity:98%Color and Shape:SolidMolecular weight:526.54Ethacrynate Sodium
CAS:Ethacrynate Sodium, a sodium salt, blocks chloride, potassium, and sodium transport mainly in Henle's loop.Formula:C13H12Cl2NaO4Purity:98%Color and Shape:SolidMolecular weight:326.12A 80b
CAS:A-80b: synthetic pyridazinoindole; potent, lasting antihypertensive; lowers diastolic more; no change in heart rate; inhibits Ca2+-induced contraction.Formula:C16H17N7Purity:98%Color and Shape:SolidMolecular weight:307.35AJG-049 free base
CAS:AJG-049 free base is a calcium channel antagonist that inhibits L-type Ca2+ channels via diltiazem-binding site(s).Formula:C27H30N2O2Color and Shape:SolidMolecular weight:414.54Azelnidipine, (S)-
CAS:Azelnidipine, a selective L-type CCB, improves HF severity and cardiac function in HT and HFpEF compared to N-type CCB cilnidipine.Formula:C33H34N4O6Color and Shape:SolidMolecular weight:582.65UK-52831
CAS:UK-52831, a calcium channel antagonist, is used potentially for the treatment of hypertension and myocardia ischemia.Formula:C22H26Cl2N6O5Purity:98%Color and Shape:SolidMolecular weight:525.39
![4-(2-Chlorophenyl)-2-methyl-5-oxo-4,4a,5,7,8,10-hexahydro-1H-pyrido[2',3':2,3]azeto[2,1-c][1,4]oxa…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FC609788.webp&w=3840&q=75)
